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The map label for this gene is fnr [H]

Identifier: 17546002

GI number: 17546002

Start: 1364728

End: 1365456

Strand: Reverse

Name: fnr [H]

Synonym: RSc1283

Alternate gene names: 17546002

Gene position: 1365456-1364728 (Counterclockwise)

Preceding gene: 17546011

Following gene: 17545992

Centisome position: 36.74

GC content: 62.55

Gene sequence:

>729_bases
GTGCTCACACGAATCGCACTCACCGATCAAACCTCCCGTTGCTCCACCTGCGTGCTCGGACAAATCTGTCTGCCGGTAGG
CATGAACGCGGACGACGTGCGCAAGATGGATGATCTGGTCACCGAACGCATCCGCATCAAGAAAGGCCAGGTGCTCTACG
CACTGGGTGAACCGCTGGAAGCGGTCTACGGCATCCGTTTCGGCACACTGAAAACCCATCTGACGCTGGAAGACGGCCGC
CACCAGATCACAGGCTTCCATCTGCCCGGCGAAATCGTCGGGCTCGACGGCATCGGCGAAATGCGCCACGTATCGGATGC
CACCGCGCTGGAAGATACCGAAGTCTGCGTGGTGCGCTATGCCGAACTGCAGCAGCTGTCGCGCCGACTGCCTTCGCTGC
AGCACCAGTTCCTGCGCATCATGAGCAAGGAGATTTCGCAGGATCACCTGATGCTGCTGACCCTCGGCTCGATGCGCGCG
GAAGAGCGCCTCGCCGCCTTCCTGCTGAACCTGTCGCGCCGCTCGGCTGAGCGTGGCTATTCCTCGACCGAATTCGTCCT
GCGCATGAGCCGCGAAGAACTCGGCAGCTATCTGGGCCTGAAGCTGGAGACCGTCAGCCGCCTGTTCTCGCGCTTTGCCG
AAGCGGGGCTGATCCAGATCCGCCAACGCCACGTCAAGCTGATCGACATGGCCGGCCTGCGCCAGGTGATGACCGGCCAC
GCCGGCTGA

Upstream 100 bases:

>100_bases
AACATCGAAGACCGCCGATAACAGCGGGGGCGCCGTTATAATGCGGCTGCGGTTGCTCACAGATTTTCGATCTCACTTTC
CTCGGAATTTCTTCGCCCCC

Downstream 100 bases:

>100_bases
TCGCCTACCACGGCATCCGCTCAGATGAGCGGATGTTCGTGCGCTTCCAGCTTGCCGATTCCCGGCGACACATACAGCGT
CAGCGCGCTCGACAACCCGC

Product: fumarate and nitrate reduction regulatory transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MLTRIALTDQTSRCSTCVLGQICLPVGMNADDVRKMDDLVTERIRIKKGQVLYALGEPLEAVYGIRFGTLKTHLTLEDGR
HQITGFHLPGEIVGLDGIGEMRHVSDATALEDTEVCVVRYAELQQLSRRLPSLQHQFLRIMSKEISQDHLMLLTLGSMRA
EERLAAFLLNLSRRSAERGYSSTEFVLRMSREELGSYLGLKLETVSRLFSRFAEAGLIQIRQRHVKLIDMAGLRQVMTGH
AG

Sequences:

>Translated_242_residues
MLTRIALTDQTSRCSTCVLGQICLPVGMNADDVRKMDDLVTERIRIKKGQVLYALGEPLEAVYGIRFGTLKTHLTLEDGR
HQITGFHLPGEIVGLDGIGEMRHVSDATALEDTEVCVVRYAELQQLSRRLPSLQHQFLRIMSKEISQDHLMLLTLGSMRA
EERLAAFLLNLSRRSAERGYSSTEFVLRMSREELGSYLGLKLETVSRLFSRFAEAGLIQIRQRHVKLIDMAGLRQVMTGH
AG
>Mature_242_residues
MLTRIALTDQTSRCSTCVLGQICLPVGMNADDVRKMDDLVTERIRIKKGQVLYALGEPLEAVYGIRFGTLKTHLTLEDGR
HQITGFHLPGEIVGLDGIGEMRHVSDATALEDTEVCVVRYAELQQLSRRLPSLQHQFLRIMSKEISQDHLMLLTLGSMRA
EERLAAFLLNLSRRSAERGYSSTEFVLRMSREELGSYLGLKLETVSRLFSRFAEAGLIQIRQRHVKLIDMAGLRQVMTGH
AG

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=227, Percent_Identity=42.7312775330396, Blast_Score=206, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27225; Mature: 27225

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRIALTDQTSRCSTCVLGQICLPVGMNADDVRKMDDLVTERIRIKKGQVLYALGEPLE
CCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHH
AVYGIRFGTLKTHLTLEDGRHQITGFHLPGEIVGLDGIGEMRHVSDATALEDTEVCVVRY
HHHCCCCCCEEEEEEECCCCEEEEEEECCCCEEECCCCCHHHHHCCCHHCCCCHHHHHHH
AELQQLSRRLPSLQHQFLRIMSKEISQDHLMLLTLGSMRAEERLAAFLLNLSRRSAERGY
HHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
SSTEFVLRMSREELGSYLGLKLETVSRLFSRFAEAGLIQIRQRHVKLIDMAGLRQVMTGH
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AG
CC
>Mature Secondary Structure
MLTRIALTDQTSRCSTCVLGQICLPVGMNADDVRKMDDLVTERIRIKKGQVLYALGEPLE
CCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHH
AVYGIRFGTLKTHLTLEDGRHQITGFHLPGEIVGLDGIGEMRHVSDATALEDTEVCVVRY
HHHCCCCCCEEEEEEECCCCEEEEEEECCCCEEECCCCCHHHHHCCCHHCCCCHHHHHHH
AELQQLSRRLPSLQHQFLRIMSKEISQDHLMLLTLGSMRAEERLAAFLLNLSRRSAERGY
HHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
SSTEFVLRMSREELGSYLGLKLETVSRLFSRFAEAGLIQIRQRHVKLIDMAGLRQVMTGH
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]