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The map label for this gene is hfq [H]

Identifier: 17545939

GI number: 17545939

Start: 1290132

End: 1290371

Strand: Direct

Name: hfq [H]

Synonym: RSc1220

Alternate gene names: 17545939

Gene position: 1290132-1290371 (Clockwise)

Preceding gene: 17545938

Following gene: 17545940

Centisome position: 34.71

GC content: 53.75

Gene sequence:

>240_bases
ATGAGCAACAAAGGGCAATTGCTACAAGACCCGTTTCTGAATGCGCTGCGTAAGGAGCATGTGCCGGTGTCGATCTATCT
CGTCAACGGTATCAAGCTGCAAGGCAATATCGAATCGTTCGACCAATATGTCGTTCTGCTGCGCAATACCGTCACGCAGA
TGGTGTACAAGCATGCGATTTCCACTGTGGTGCCGGCGCGTGCCGTGAATTTCCGCGTGGATGAGGCCTCCGACGCCTGA

Upstream 100 bases:

>100_bases
TGGCCGACTCTTTTGACGAACTTTTTTTGCGTCGCCTGCTTGAATCAGGGGTCCCCGGCCCCCATAACCCATCACTAAAC
CTATAAATCTGGAGTGTGCC

Downstream 100 bases:

>100_bases
GTCGTCGCCTGACCGCCCGCCGCCGTTCGCGCGGCGGGTGCATCTCCCCCGGTTTTCCCCGTTTCCCCCAATTCCCGCTT
GCCATCCCATCCCACCTCCA

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 79; Mature: 78

Protein sequence:

>79_residues
MSNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAISTVVPARAVNFRVDEASDA

Sequences:

>Translated_79_residues
MSNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAISTVVPARAVNFRVDEASDA
>Mature_78_residues
SNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAISTVVPARAVNFRVDEASDA

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=76, Percent_Identity=75, Blast_Score=122, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 8872; Mature: 8741

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAI
CCCCCCCHHHHHHHHHHHCCCCEEEEEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
STVVPARAVNFRVDEASDA
HHHCCCHHEEEECCCCCCC
>Mature Secondary Structure 
SNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAI
CCCCCCHHHHHHHHHHHCCCCEEEEEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
STVVPARAVNFRVDEASDA
HHHCCCHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA