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The map label for this gene is engA [H]

Identifier: 17545938

GI number: 17545938

Start: 1288497

End: 1289840

Strand: Direct

Name: engA [H]

Synonym: RSc1219

Alternate gene names: 17545938

Gene position: 1288497-1289840 (Clockwise)

Preceding gene: 17545937

Following gene: 17545939

Centisome position: 34.67

GC content: 65.4

Gene sequence:

>1344_bases
ATGAAACCAGTCATCGCCCTCGTGGGGCGGCCGAATGTCGGCAAATCGACCCTGTTCAACCGCCTGACGCGCTCGCGTGA
CGCGCTCGTCGCGGACATGCCGGGCCTGACGCGCGACCGCCACTACGGCGAGGGTCGCGTCGGCGAGCGTCCGTTTATCG
CCATCGATACCGGCGGCTTCGAGCCCGTTGCCAAGGAAGGCATCGTTGCCGAGATGGCCAAGCAGACACGCCAGGCCGTG
GTCGAGGCCGACGTGGTCATCTTCATCGTCGACGGACGCCTGGGGCTGGCGCCCCAGGACCGCGTGATCGCGGACTACCT
GCGCAAGACCGGCCGCCGCATCCTGCTGGCCGTCAACAAGGCCGAAGGCATGAAGTACACCGCCGTGGCCACCGACTTCT
ATGAGCTGGGCCTGGGCGATCCGCGCGCCATCTCCTCCGCTCATGGCGACGGTGTGCGCGAACTCGTGGACGAGGCGCTC
GATCTGGCGTTCGCCGAGCGTCCCGAGCTTGCCGAGGCAGCGGAGGGTCACGACCACGGCACGCGCATCGCCATCGTTGG
CCGGCCGAATGTGGGCAAGTCGACCCTGGTGAACGCGCTGATCGGCGAGGAGCGCGTGATCGCGTTCGACATGCCCGGCA
CCACGCGCGACGCCATCTACGTGGACTTCGAGCGCAACGGCAAGCCGTACACCCTCATCGATACGGCCGGCCTGCGCAAG
CGCGGCAAGGTGTTCGAGGCGATCGAGAAGTTCTCGGTGGTCAAGACGCTGCAGTCCATCGCGGATGCCAATGTGGTGGT
GCTGCTGCTCGATGCGCAGCAGGACATTTCCGACCAGGACGCGCACATCGCGGGCTTCATCGTGGAGTCGGGGCGGGCGC
TGGTGATCGGCGTCAACAAGTGGGACGGCCTGGACGGCCACGCGCGCGATCGCATCAAGCACGACATGGAGCGCAAGCTG
CAGTTCCTGTCGTTCGCCAACGTGCACTACATTTCGGCCAAGCAGCGCACCGGCATCGGCGCATTGATGAAATCGGTGGA
CGACGCTTACGCCGCTGCCATGGTCAAGCTGCCGACGCCCAAGCTCACGCGCGTGCTGCAGGAGGCGGTCGAGTTCCAGC
AGCCGCGGCGCGCCGGCGTCTCTCGACCGAAGCTGCGCTATGCGCACCAGGGCGGTTCCAATCCGCCGATCGTGGTGATC
CACGGGAATGCGCTGTCGAATATCCCGGAAACCTATCGCCGTTTTCTGGAAGGTCGGTTTCGCGACGCTTTCCAGCTCAA
AGGCACGCCGCTGCGGATCGAATTTCGTACGAACAAAAACCCGTACGCCCAATCCAACGAGTGA

Upstream 100 bases:

>100_bases
ATCGCGGGCGCGTTGCATCTGTGCGGAGGGCCGTGCCGGTGCCCGTTGAGCTGCATCAACCCGAATCTACCGCGGCGCCA
TTCGCGCGCGGCGCATACGC

Downstream 100 bases:

>100_bases
GGGCTGCGTCGGCAGTGCTCGACAGTGGGAGCGTGTGGCGCGGGGAGGCGCAAAGGCAGCGCGGGAGGAATCACCAGAAC
GCCGGGCAGGGCTGCATCGT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADMPGLTRDRHYGEGRVGERPFIAIDTGGFEPVAKEGIVAEMAKQTRQAV
VEADVVIFIVDGRLGLAPQDRVIADYLRKTGRRILLAVNKAEGMKYTAVATDFYELGLGDPRAISSAHGDGVRELVDEAL
DLAFAERPELAEAAEGHDHGTRIAIVGRPNVGKSTLVNALIGEERVIAFDMPGTTRDAIYVDFERNGKPYTLIDTAGLRK
RGKVFEAIEKFSVVKTLQSIADANVVVLLLDAQQDISDQDAHIAGFIVESGRALVIGVNKWDGLDGHARDRIKHDMERKL
QFLSFANVHYISAKQRTGIGALMKSVDDAYAAAMVKLPTPKLTRVLQEAVEFQQPRRAGVSRPKLRYAHQGGSNPPIVVI
HGNALSNIPETYRRFLEGRFRDAFQLKGTPLRIEFRTNKNPYAQSNE

Sequences:

>Translated_447_residues
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADMPGLTRDRHYGEGRVGERPFIAIDTGGFEPVAKEGIVAEMAKQTRQAV
VEADVVIFIVDGRLGLAPQDRVIADYLRKTGRRILLAVNKAEGMKYTAVATDFYELGLGDPRAISSAHGDGVRELVDEAL
DLAFAERPELAEAAEGHDHGTRIAIVGRPNVGKSTLVNALIGEERVIAFDMPGTTRDAIYVDFERNGKPYTLIDTAGLRK
RGKVFEAIEKFSVVKTLQSIADANVVVLLLDAQQDISDQDAHIAGFIVESGRALVIGVNKWDGLDGHARDRIKHDMERKL
QFLSFANVHYISAKQRTGIGALMKSVDDAYAAAMVKLPTPKLTRVLQEAVEFQQPRRAGVSRPKLRYAHQGGSNPPIVVI
HGNALSNIPETYRRFLEGRFRDAFQLKGTPLRIEFRTNKNPYAQSNE
>Mature_447_residues
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADMPGLTRDRHYGEGRVGERPFIAIDTGGFEPVAKEGIVAEMAKQTRQAV
VEADVVIFIVDGRLGLAPQDRVIADYLRKTGRRILLAVNKAEGMKYTAVATDFYELGLGDPRAISSAHGDGVRELVDEAL
DLAFAERPELAEAAEGHDHGTRIAIVGRPNVGKSTLVNALIGEERVIAFDMPGTTRDAIYVDFERNGKPYTLIDTAGLRK
RGKVFEAIEKFSVVKTLQSIADANVVVLLLDAQQDISDQDAHIAGFIVESGRALVIGVNKWDGLDGHARDRIKHDMERKL
QFLSFANVHYISAKQRTGIGALMKSVDDAYAAAMVKLPTPKLTRVLQEAVEFQQPRRAGVSRPKLRYAHQGGSNPPIVVI
HGNALSNIPETYRRFLEGRFRDAFQLKGTPLRIEFRTNKNPYAQSNE

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=469, Percent_Identity=50.5330490405117, Blast_Score=460, Evalue=1e-131,
Organism=Escherichia coli, GI2367268, Length=103, Percent_Identity=39.8058252427184, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788919, Length=124, Percent_Identity=34.6774193548387, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=179, Percent_Identity=27.3743016759777, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49226; Mature: 49226

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADMPGLTRDRHYGEGRVGERPFIAIDTGGF
CCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EPVAKEGIVAEMAKQTRQAVVEADVVIFIVDGRLGLAPQDRVIADYLRKTGRRILLAVNK
CHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEEC
AEGMKYTAVATDFYELGLGDPRAISSAHGDGVRELVDEALDLAFAERPELAEAAEGHDHG
CCCCEEEEEEHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCC
TRIAIVGRPNVGKSTLVNALIGEERVIAFDMPGTTRDAIYVDFERNGKPYTLIDTAGLRK
CEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEECCCCCH
RGKVFEAIEKFSVVKTLQSIADANVVVLLLDAQQDISDQDAHIAGFIVESGRALVIGVNK
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEECCC
WDGLDGHARDRIKHDMERKLQFLSFANVHYISAKQRTGIGALMKSVDDAYAAAMVKLPTP
CCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHEEECCCH
KLTRVLQEAVEFQQPRRAGVSRPKLRYAHQGGSNPPIVVIHGNALSNIPETYRRFLEGRF
HHHHHHHHHHHHCCHHHCCCCCCCCHHHHCCCCCCCEEEEECCHHHCCHHHHHHHHHHHC
RDAFQLKGTPLRIEFRTNKNPYAQSNE
CCCEEECCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADMPGLTRDRHYGEGRVGERPFIAIDTGGF
CCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EPVAKEGIVAEMAKQTRQAVVEADVVIFIVDGRLGLAPQDRVIADYLRKTGRRILLAVNK
CHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEEC
AEGMKYTAVATDFYELGLGDPRAISSAHGDGVRELVDEALDLAFAERPELAEAAEGHDHG
CCCCEEEEEEHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCC
TRIAIVGRPNVGKSTLVNALIGEERVIAFDMPGTTRDAIYVDFERNGKPYTLIDTAGLRK
CEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEECCCCCH
RGKVFEAIEKFSVVKTLQSIADANVVVLLLDAQQDISDQDAHIAGFIVESGRALVIGVNK
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEECCC
WDGLDGHARDRIKHDMERKLQFLSFANVHYISAKQRTGIGALMKSVDDAYAAAMVKLPTP
CCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHEEECCCH
KLTRVLQEAVEFQQPRRAGVSRPKLRYAHQGGSNPPIVVIHGNALSNIPETYRRFLEGRF
HHHHHHHHHHHHCCHHHCCCCCCCCHHHHCCCCCCCEEEEECCHHHCCHHHHHHHHHHHC
RDAFQLKGTPLRIEFRTNKNPYAQSNE
CCCEEECCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA