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The map label for this gene is nagL [H]

Identifier: 17545804

GI number: 17545804

Start: 1143569

End: 1144210

Strand: Reverse

Name: nagL [H]

Synonym: RSc1085

Alternate gene names: 17545804

Gene position: 1144210-1143569 (Counterclockwise)

Preceding gene: 17545805

Following gene: 17545803

Centisome position: 30.79

GC content: 72.12

Gene sequence:

>642_bases
ATGCAGCTCTACAGCTTCTTCAACAGCTCCACGTCGTACCGCGTGCGCATCGCGCTGGCGCTCAAGGGGCTGCCGTACGA
CTACCTGCCGGTCAACATCCGCACCGGCGAGCATCGCGCGGCAGACTACGTCGCGCACGTCAACCCGTCGGCGGGCGTCC
CCACGCTGGTCGACGGCGCGCTGCGGCTCGGCCAGTCGCTGGCGATCATCGACTACCTCGACGCGCGCCATCCGCAGCCG
CGCCTCGTTCCCGCCGATCCGCTGCGGCGGGCCCGCGTGCTGGAGCTGGCCAGCGCCATCGCCTGCGACATCCACCCGGT
CAACAACCTGCGCGTGCTGCGCTACCTGCAGGACGAACTGAAGGTGACGCCGCAGCAGAAGGACGCCTGGTACCGCCACT
GGATCGACGAGGGGCTGGCCAGCGTGGAGCGCCTGCTGGCCCGCCACGGGCACGGCCCCTGGTGCTTCGGCGACGCACCG
ACGCTGGCGGACGTGGCGCTCGTGCCGCAGGTCGCCAACGCGCTGCGCATGGGTTGCCCGCTCGATCGGTTCGAGCGCGT
GCTGGCCGTGCATGCGCACGCGGGCACGCACCCCGCCTTCGCCGAGGCCGCGCCGGCGCGCCAGCCCGACTACACGGCCT
GA

Upstream 100 bases:

>100_bases
ACCGGCACCCCGGAGGGCGTGGGTGCGGTCAAGCCCGGCGACACCATCGCGACGGGGGTCGACGGCCTGGGTGAACTGAA
CGTCCGCATCGCCTGACGCC

Downstream 100 bases:

>100_bases
CGGCGAGCCCACAACCCAGCGCCATGTCCTGACCGGGAGGTACCGCACACACGCACATCACCGGACCGAGTCCGCCCATC
GCTCCAGCACCGTACCGGCC

Product: GST-related protein

Products: NA

Alternate protein names: MAAI [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MQLYSFFNSSTSYRVRIALALKGLPYDYLPVNIRTGEHRAADYVAHVNPSAGVPTLVDGALRLGQSLAIIDYLDARHPQP
RLVPADPLRRARVLELASAIACDIHPVNNLRVLRYLQDELKVTPQQKDAWYRHWIDEGLASVERLLARHGHGPWCFGDAP
TLADVALVPQVANALRMGCPLDRFERVLAVHAHAGTHPAFAEAAPARQPDYTA

Sequences:

>Translated_213_residues
MQLYSFFNSSTSYRVRIALALKGLPYDYLPVNIRTGEHRAADYVAHVNPSAGVPTLVDGALRLGQSLAIIDYLDARHPQP
RLVPADPLRRARVLELASAIACDIHPVNNLRVLRYLQDELKVTPQQKDAWYRHWIDEGLASVERLLARHGHGPWCFGDAP
TLADVALVPQVANALRMGCPLDRFERVLAVHAHAGTHPAFAEAAPARQPDYTA
>Mature_213_residues
MQLYSFFNSSTSYRVRIALALKGLPYDYLPVNIRTGEHRAADYVAHVNPSAGVPTLVDGALRLGQSLAIIDYLDARHPQP
RLVPADPLRRARVLELASAIACDIHPVNNLRVLRYLQDELKVTPQQKDAWYRHWIDEGLASVERLLARHGHGPWCFGDAP
TLADVALVPQVANALRMGCPLDRFERVLAVHAHAGTHPAFAEAAPARQPDYTA

Specific function: Forms An Equimolar Complex With The RNA Polymerase Holoenzyme (Rnap) But Not With The Core Enzyme. It Is Synthesized Predominantly When Cells Are Exposed To Amino Acid Starvation, At Which Time It Accounts For Over 50% Of The Total Protein Synthesized. It

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI22202624, Length=209, Percent_Identity=40.6698564593301, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI22202622, Length=158, Percent_Identity=38.6075949367089, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17551302, Length=213, Percent_Identity=36.150234741784, Blast_Score=128, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17510461, Length=209, Percent_Identity=34.4497607655502, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17556142, Length=209, Percent_Identity=34.4497607655502, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI21355859, Length=209, Percent_Identity=38.755980861244, Blast_Score=140, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24645375, Length=209, Percent_Identity=38.755980861244, Blast_Score=140, Evalue=5e-34,
Organism=Drosophila melanogaster, GI45553325, Length=209, Percent_Identity=38.755980861244, Blast_Score=140, Evalue=6e-34,
Organism=Drosophila melanogaster, GI21355857, Length=210, Percent_Identity=36.1904761904762, Blast_Score=137, Evalue=6e-33,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1982 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR005955
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =5.2.1.2 [H]

Molecular weight: Translated: 23607; Mature: 23607

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLYSFFNSSTSYRVRIALALKGLPYDYLPVNIRTGEHRAADYVAHVNPSAGVPTLVDGA
CCHHHHHCCCCCEEEEEEEEECCCCCCEEEEEEECCCCHHHHHEEECCCCCCCCHHHHHH
LRLGQSLAIIDYLDARHPQPRLVPADPLRRARVLELASAIACDIHPVNNLRVLRYLQDEL
HHHCCCHHEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
KVTPQQKDAWYRHWIDEGLASVERLLARHGHGPWCFGDAPTLADVALVPQVANALRMGCP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCC
LDRFERVLAVHAHAGTHPAFAEAAPARQPDYTA
HHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MQLYSFFNSSTSYRVRIALALKGLPYDYLPVNIRTGEHRAADYVAHVNPSAGVPTLVDGA
CCHHHHHCCCCCEEEEEEEEECCCCCCEEEEEEECCCCHHHHHEEECCCCCCCCHHHHHH
LRLGQSLAIIDYLDARHPQPRLVPADPLRRARVLELASAIACDIHPVNNLRVLRYLQDEL
HHHCCCHHEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
KVTPQQKDAWYRHWIDEGLASVERLLARHGHGPWCFGDAPTLADVALVPQVANALRMGCP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCC
LDRFERVLAVHAHAGTHPAFAEAAPARQPDYTA
HHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]