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The map label for this gene is uxuR [H]

Identifier: 17545797

GI number: 17545797

Start: 1133936

End: 1134703

Strand: Reverse

Name: uxuR [H]

Synonym: RSc1078

Alternate gene names: 17545797

Gene position: 1134703-1133936 (Counterclockwise)

Preceding gene: 17545803

Following gene: 17545789

Centisome position: 30.53

GC content: 71.74

Gene sequence:

>768_bases
ATGTCCGCCCCCGGCTCTCCCGCCACGCTTGCGCGCCGCACCCAAAGCCTCGCAGAGGCCGTGGTCGACCACATCGGCCA
GCGCATCGCCTCGGGGTCGCTGCGCCCCGGCGACAAGCTGCCCACCGAGTCCGAACTGATGGGCATGCTGGGCGTGAGCC
GCACCGTGGTGCGCGAGGCCATCTCGCGGCTGCAGGCCAAGGCCCTGATCGAAACCCGCCACGGCATCGGCAGCTTCGTG
CTGGAGCCGCGGGCCGAGACCGCGATCCAGCTGGGTGCCGCCTCCACGCTCCAGGACATCCTGGCGATGCTGGAGCTGCG
CGTCGCCCTGGAGACCGAATGCGCCGGCCTGGCCGCCCAGCGCGCCACGCCGGAAGACCTTACCGGCCTGCGCAACGCGC
TGGACGCGTTCGAGCAGGACCAGGCCAGCGGCAGCGACAGCGCCGCCTCCGACCTGCGCTTCCACCTCGCGATCGCGCAC
GCCACCCGCAACCAGCACTTCGTCGCCGTGCTCGACCAGCTCGGCAAGACGCTGATCCCCCGCAGCCGGATCGCGCCGAC
GCAGGTCGGCTACCTGAATACACCGGAATCGCGCGCGACCGTCAGCCGCGAACACCGCAGCATCTACGAAGCCATCTCGC
GCCAGGACCCGGAAGCCGCGCGCGCGGCCATGCGCATGCACCTGTCCAACAGCCGCGAACGGCTGCGCCGCGCGCACGGC
CAGGCCGGACATCCCGCCCCGGAAACAGTCCCACCGGAATCGACCTGA

Upstream 100 bases:

>100_bases
CGTATGTTATCAGTCGTCGTACAACATGCGATCGGACTATAATGGACACGTCCTTGCAGGTACACCCCTGGTAAACCCCG
AACACCCCACCGGAAACAGC

Downstream 100 bases:

>100_bases
GGCTCTCCGCCTTCACGATCGGCCAGGCTGCGGACCAAGTCATACGACATCCTATAAGTTAGCGTATAAGGCATCTCCGG
GACGCCTGTGGCCACCCTCA

Product: transcriptional regulatory DNA-binding transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSAPGSPATLARRTQSLAEAVVDHIGQRIASGSLRPGDKLPTESELMGMLGVSRTVVREAISRLQAKALIETRHGIGSFV
LEPRAETAIQLGAASTLQDILAMLELRVALETECAGLAAQRATPEDLTGLRNALDAFEQDQASGSDSAASDLRFHLAIAH
ATRNQHFVAVLDQLGKTLIPRSRIAPTQVGYLNTPESRATVSREHRSIYEAISRQDPEAARAAMRMHLSNSRERLRRAHG
QAGHPAPETVPPEST

Sequences:

>Translated_255_residues
MSAPGSPATLARRTQSLAEAVVDHIGQRIASGSLRPGDKLPTESELMGMLGVSRTVVREAISRLQAKALIETRHGIGSFV
LEPRAETAIQLGAASTLQDILAMLELRVALETECAGLAAQRATPEDLTGLRNALDAFEQDQASGSDSAASDLRFHLAIAH
ATRNQHFVAVLDQLGKTLIPRSRIAPTQVGYLNTPESRATVSREHRSIYEAISRQDPEAARAAMRMHLSNSRERLRRAHG
QAGHPAPETVPPEST
>Mature_254_residues
SAPGSPATLARRTQSLAEAVVDHIGQRIASGSLRPGDKLPTESELMGMLGVSRTVVREAISRLQAKALIETRHGIGSFVL
EPRAETAIQLGAASTLQDILAMLELRVALETECAGLAAQRATPEDLTGLRNALDAFEQDQASGSDSAASDLRFHLAIAHA
TRNQHFVAVLDQLGKTLIPRSRIAPTQVGYLNTPESRATVSREHRSIYEAISRQDPEAARAAMRMHLSNSRERLRRAHGQ
AGHPAPETVPPEST

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=214, Percent_Identity=34.5794392523364, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1790032, Length=251, Percent_Identity=32.2709163346614, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082208, Length=215, Percent_Identity=32.093023255814, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786303, Length=234, Percent_Identity=32.9059829059829, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI48994955, Length=232, Percent_Identity=31.4655172413793, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789353, Length=245, Percent_Identity=29.7959183673469, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789621, Length=240, Percent_Identity=31.25, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27440; Mature: 27309

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPGSPATLARRTQSLAEAVVDHIGQRIASGSLRPGDKLPTESELMGMLGVSRTVVREA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ISRLQAKALIETRHGIGSFVLEPRAETAIQLGAASTLQDILAMLELRVALETECAGLAAQ
HHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RATPEDLTGLRNALDAFEQDQASGSDSAASDLRFHLAIAHATRNQHFVAVLDQLGKTLIP
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
RSRIAPTQVGYLNTPESRATVSREHRSIYEAISRQDPEAARAAMRMHLSNSRERLRRAHG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
QAGHPAPETVPPEST
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAPGSPATLARRTQSLAEAVVDHIGQRIASGSLRPGDKLPTESELMGMLGVSRTVVREA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ISRLQAKALIETRHGIGSFVLEPRAETAIQLGAASTLQDILAMLELRVALETECAGLAAQ
HHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RATPEDLTGLRNALDAFEQDQASGSDSAASDLRFHLAIAHATRNQHFVAVLDQLGKTLIP
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
RSRIAPTQVGYLNTPESRATVSREHRSIYEAISRQDPEAARAAMRMHLSNSRERLRRAHG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
QAGHPAPETVPPEST
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]