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The map label for this gene is yhfN [H]

Identifier: 17545660

GI number: 17545660

Start: 989593

End: 990849

Strand: Reverse

Name: yhfN [H]

Synonym: RSc0941

Alternate gene names: 17545660

Gene position: 990849-989593 (Counterclockwise)

Preceding gene: 17545662

Following gene: 17545659

Centisome position: 26.66

GC content: 66.91

Gene sequence:

>1257_bases
ATGCCCACCTTCACCGCCGTCTTCCTGATCGCCCTCGTGCTGATGGCCGCCACACGCCTGTGGCTGGCCGCCCGGCAGAT
CCGCCACGTGGCGCGCCACCGTGACACCGTGCCCGCGCAGTTCGCCGAATCCATCACACTGGACATGCACCACAAGGCCG
CCGACTACACCATCGCCCGCACGCGCCTGGCGATGCTGGAAGTCCCCGTGCAGGCCACGCTGCTGATCGCGCTGACGCTG
CTGGGCGGGCTGAACGGGCTCAACCAGGCCTGGCTGTCCGCCTTCGGCCCCGGCTACGCGTATGGCGTGGCCCTGATCGC
CTCGGTCATCGCCATCAGCAGCCTGATCGAGCTGCCGTTCTCGCTGTACAGCCAGTTCGTCGTCGAAGAGCGCTTCGGCT
TCAACCGCATGACCTGGAAGCTGTGGCTGGCCGACAACCTCAAGGGGCTGGCCATCGGCACCGCGCTGGGGCTGCCGCTG
CTGCTGGCGGTGCTGTGGCTGATGCACTCGATGGGCGAGCGCTGGTGGCTGTACACCTGGCTGGTGTGGATGGCCTTCAC
GCTGTTCGTCCAGGCGATCTACCCCAACGTGATCGCCCCGCTCTACAACAAGTTCACCCCGCTCGAGGACGGCGAGATGC
GCACGCGCATCGAGGGCTTGCTCAAGCGCTGCGGCTTTGCCAGCAAGGGCCTGTTCGTGATGGACGGCAGCCGCCGCAGC
GCCCACGGCAACGCCTATTTCAGCGGCTTCGGCGCCACCAAGCGCATCGTCTTCTTCGACACGCTGCTCGCGCGGCTGGA
TGCCCCCGAGATGGAAGCCGTGCTGGCGCATGAGCTGGGCCATTTCAAGCGCCACCACGTCACCAAGCGCATCGCCGTGA
TGTTCGTGCTGAGCCTGGGGCTGCTGGCCCTGCTCGGCTGGCTGATGACGCGCGCGTGGTTCTACCTGGGCCTGGGCGTG
GCGCCCAACCTGCTCGCCGACAACCATGCGCTGGCGCTGATGCTGTTCTTCCTGGTACTGCCGGTCTTCATGTTCTTCGT
CTCGCCGCTGTCGAGCCTGTCGTCCCGCAAGCACGAGTTCGAGGCGGATGCCTTCGCGGCGCAGCATGCCGATGCGTCGC
GCCTGGTCTCGGCGCTGGTCAAGCTGTTCCAGGACAATGCTTCGACCCTGACGCCCGACCCGGTCTACTCGGCGTTCTAC
TACTCCCACCCCACCGCGTCGCAGCGCGTGGCACGACTGGTGCAGGCTGCCGCATGA

Upstream 100 bases:

>100_bases
AGATGCCGCAGCCGGCTGGGAAAGAGGGGTGCTCACGCGAAAGCCTTGAGAAATGAACGGAAGGCTATAATTTTCGCATA
TCTGATAGCTGTTCCCACAC

Downstream 100 bases:

>100_bases
CGCGCGGCAAACCGGGCCGCGCGGGTCACGACAGGCGGCACGCCAGCACCGGCGAACATGGGCTGGTGATCGCCGCGCAT
GGCCGTCATTACCTCGTCGA

Product: integral membrane protease transmembrane protein

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MPTFTAVFLIALVLMAATRLWLAARQIRHVARHRDTVPAQFAESITLDMHHKAADYTIARTRLAMLEVPVQATLLIALTL
LGGLNGLNQAWLSAFGPGYAYGVALIASVIAISSLIELPFSLYSQFVVEERFGFNRMTWKLWLADNLKGLAIGTALGLPL
LLAVLWLMHSMGERWWLYTWLVWMAFTLFVQAIYPNVIAPLYNKFTPLEDGEMRTRIEGLLKRCGFASKGLFVMDGSRRS
AHGNAYFSGFGATKRIVFFDTLLARLDAPEMEAVLAHELGHFKRHHVTKRIAVMFVLSLGLLALLGWLMTRAWFYLGLGV
APNLLADNHALALMLFFLVLPVFMFFVSPLSSLSSRKHEFEADAFAAQHADASRLVSALVKLFQDNASTLTPDPVYSAFY
YSHPTASQRVARLVQAAA

Sequences:

>Translated_418_residues
MPTFTAVFLIALVLMAATRLWLAARQIRHVARHRDTVPAQFAESITLDMHHKAADYTIARTRLAMLEVPVQATLLIALTL
LGGLNGLNQAWLSAFGPGYAYGVALIASVIAISSLIELPFSLYSQFVVEERFGFNRMTWKLWLADNLKGLAIGTALGLPL
LLAVLWLMHSMGERWWLYTWLVWMAFTLFVQAIYPNVIAPLYNKFTPLEDGEMRTRIEGLLKRCGFASKGLFVMDGSRRS
AHGNAYFSGFGATKRIVFFDTLLARLDAPEMEAVLAHELGHFKRHHVTKRIAVMFVLSLGLLALLGWLMTRAWFYLGLGV
APNLLADNHALALMLFFLVLPVFMFFVSPLSSLSSRKHEFEADAFAAQHADASRLVSALVKLFQDNASTLTPDPVYSAFY
YSHPTASQRVARLVQAAA
>Mature_417_residues
PTFTAVFLIALVLMAATRLWLAARQIRHVARHRDTVPAQFAESITLDMHHKAADYTIARTRLAMLEVPVQATLLIALTLL
GGLNGLNQAWLSAFGPGYAYGVALIASVIAISSLIELPFSLYSQFVVEERFGFNRMTWKLWLADNLKGLAIGTALGLPLL
LAVLWLMHSMGERWWLYTWLVWMAFTLFVQAIYPNVIAPLYNKFTPLEDGEMRTRIEGLLKRCGFASKGLFVMDGSRRSA
HGNAYFSGFGATKRIVFFDTLLARLDAPEMEAVLAHELGHFKRHHVTKRIAVMFVLSLGLLALLGWLMTRAWFYLGLGVA
PNLLADNHALALMLFFLVLPVFMFFVSPLSSLSSRKHEFEADAFAAQHADASRLVSALVKLFQDNASTLTPDPVYSAFYY
SHPTASQRVARLVQAAA

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=473, Percent_Identity=29.8097251585624, Blast_Score=191, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI17505484, Length=431, Percent_Identity=31.322505800464, Blast_Score=187, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6322577, Length=424, Percent_Identity=31.8396226415094, Blast_Score=210, Evalue=4e-55,
Organism=Drosophila melanogaster, GI19922414, Length=431, Percent_Identity=32.2505800464037, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI78707252, Length=418, Percent_Identity=24.8803827751196, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI78707254, Length=418, Percent_Identity=24.8803827751196, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24654305, Length=447, Percent_Identity=26.1744966442953, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 46611; Mature: 46480

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTFTAVFLIALVLMAATRLWLAARQIRHVARHRDTVPAQFAESITLDMHHKAADYTIAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
TRLAMLEVPVQATLLIALTLLGGLNGLNQAWLSAFGPGYAYGVALIASVIAISSLIELPF
HHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SLYSQFVVEERFGFNRMTWKLWLADNLKGLAIGTALGLPLLLAVLWLMHSMGERWWLYTW
HHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LVWMAFTLFVQAIYPNVIAPLYNKFTPLEDGEMRTRIEGLLKRCGFASKGLFVMDGSRRS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCC
AHGNAYFSGFGATKRIVFFDTLLARLDAPEMEAVLAHELGHFKRHHVTKRIAVMFVLSLG
CCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLALLGWLMTRAWFYLGLGVAPNLLADNHALALMLFFLVLPVFMFFVSPLSSLSSRKHEF
HHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EADAFAAQHADASRLVSALVKLFQDNASTLTPDPVYSAFYYSHPTASQRVARLVQAAA
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PTFTAVFLIALVLMAATRLWLAARQIRHVARHRDTVPAQFAESITLDMHHKAADYTIAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
TRLAMLEVPVQATLLIALTLLGGLNGLNQAWLSAFGPGYAYGVALIASVIAISSLIELPF
HHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SLYSQFVVEERFGFNRMTWKLWLADNLKGLAIGTALGLPLLLAVLWLMHSMGERWWLYTW
HHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LVWMAFTLFVQAIYPNVIAPLYNKFTPLEDGEMRTRIEGLLKRCGFASKGLFVMDGSRRS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCC
AHGNAYFSGFGATKRIVFFDTLLARLDAPEMEAVLAHELGHFKRHHVTKRIAVMFVLSLG
CCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLALLGWLMTRAWFYLGLGVAPNLLADNHALALMLFFLVLPVFMFFVSPLSSLSSRKHEF
HHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EADAFAAQHADASRLVSALVKLFQDNASTLTPDPVYSAFYYSHPTASQRVARLVQAAA
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]