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The map label for this gene is mogA [H]

Identifier: 17545662

GI number: 17545662

Start: 991577

End: 992212

Strand: Reverse

Name: mogA [H]

Synonym: RSc0943

Alternate gene names: 17545662

Gene position: 992212-991577 (Counterclockwise)

Preceding gene: 17545663

Following gene: 17545660

Centisome position: 26.7

GC content: 70.6

Gene sequence:

>636_bases
ATGACCGCCTCCGCCGCCACCCGCCGCCACCCCGACGAGCTGATCGTCGGCTTCGTGTCGATTTCCGACCGCGCATCGAC
GGGCGTCTACCAGGACGAGGGGATTCCCGCGCTGCGCGACTGGTTCGGCACCGCGCTGTCGTCGCCGTGGCAAGGCGTGG
AGTGCCTGATTCCGGACGAGCAGGCCACCATCAGCGCTACGCTGATCGACCTGGTCGACCGCGTCGGCTGCGACCTCGTG
CTGACCACCGGCGGCACCGGCCCCACGCGCCGCGACGTCACGCCGGAAGCCACGTTGGCGGTCGCCACCAAGGAGATGCC
GGGCTTCGGCGAGCAGATGCGGCAGATCAGCCTGCAGTTCGTGCCGACGGCGATCCTGTCGCGGCAGGTGGCGGTGATCC
GCGAAACGCCGTCGCGCGCGGCGCTGATCATCAACCTGCCCGGCCAGCCGCGCGCCATCCGGGAAACGCTGGAAGGCCTG
AAGGACGCCGAGGGCCGCGCAACGGTGCCGGGCATCTTCGCCGCGGTGCCCTATTGCATCGACCTGATCGGCGGCCCCTA
CATCGAGACGCACGACAGCGTGGTCAAGACCTGGCGGCCCAAGCACGCCGTGCGCGCCAGGCCGCTGCAGGTCTGA

Upstream 100 bases:

>100_bases
AGTCTTCGCGCGAGCTGTTCCAGGCGGTCAAGCAGGCCTTGGCCGGCCATGATCAGGCCGGCGAAGACGCCGAACCCTCC
AACCTGGAAGACGACCAGGC

Downstream 100 bases:

>100_bases
GGCTTACGGCGCGACCGAGGAGGCCAGCGCTTCGGCTTCCGGCGTCTGCGGCACGTCGCGAATGAAATGCTGGCGGTAGT
AGCGCAGTTCTTCGATCGAT

Product: molybdenum cofactor biosynthesis protein MogA

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MTASAATRRHPDELIVGFVSISDRASTGVYQDEGIPALRDWFGTALSSPWQGVECLIPDEQATISATLIDLVDRVGCDLV
LTTGGTGPTRRDVTPEATLAVATKEMPGFGEQMRQISLQFVPTAILSRQVAVIRETPSRAALIINLPGQPRAIRETLEGL
KDAEGRATVPGIFAAVPYCIDLIGGPYIETHDSVVKTWRPKHAVRARPLQV

Sequences:

>Translated_211_residues
MTASAATRRHPDELIVGFVSISDRASTGVYQDEGIPALRDWFGTALSSPWQGVECLIPDEQATISATLIDLVDRVGCDLV
LTTGGTGPTRRDVTPEATLAVATKEMPGFGEQMRQISLQFVPTAILSRQVAVIRETPSRAALIINLPGQPRAIRETLEGL
KDAEGRATVPGIFAAVPYCIDLIGGPYIETHDSVVKTWRPKHAVRARPLQV
>Mature_210_residues
TASAATRRHPDELIVGFVSISDRASTGVYQDEGIPALRDWFGTALSSPWQGVECLIPDEQATISATLIDLVDRVGCDLVL
TTGGTGPTRRDVTPEATLAVATKEMPGFGEQMRQISLQFVPTAILSRQVAVIRETPSRAALIINLPGQPRAIRETLEGLK
DAEGRATVPGIFAAVPYCIDLIGGPYIETHDSVVKTWRPKHAVRARPLQV

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=190, Percent_Identity=34.2105263157895, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI66932975, Length=190, Percent_Identity=34.2105263157895, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1786190, Length=194, Percent_Identity=67.5257731958763, Blast_Score=265, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17564954, Length=149, Percent_Identity=33.5570469798658, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI17136978, Length=173, Percent_Identity=31.7919075144509, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24638841, Length=173, Percent_Identity=31.7919075144509, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 22767; Mature: 22636

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1 ; PS00326 TROPOMYOSIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASAATRRHPDELIVGFVSISDRASTGVYQDEGIPALRDWFGTALSSPWQGVECLIPDE
CCCCCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCC
QATISATLIDLVDRVGCDLVLTTGGTGPTRRDVTPEATLAVATKEMPGFGEQMRQISLQF
CHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHEEEEECCCCCHHHHHHHHHHHH
VPTAILSRQVAVIRETPSRAALIINLPGQPRAIRETLEGLKDAEGRATVPGIFAAVPYCI
HHHHHHHHHHHEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
DLIGGPYIETHDSVVKTWRPKHAVRARPLQV
HHHCCCCCCCCHHHHHHCCCCHHHCCCCCCC
>Mature Secondary Structure 
TASAATRRHPDELIVGFVSISDRASTGVYQDEGIPALRDWFGTALSSPWQGVECLIPDE
CCCCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCC
QATISATLIDLVDRVGCDLVLTTGGTGPTRRDVTPEATLAVATKEMPGFGEQMRQISLQF
CHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHEEEEECCCCCHHHHHHHHHHHH
VPTAILSRQVAVIRETPSRAALIINLPGQPRAIRETLEGLKDAEGRATVPGIFAAVPYCI
HHHHHHHHHHHEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
DLIGGPYIETHDSVVKTWRPKHAVRARPLQV
HHHCCCCCCCCHHHHHHCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]