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The map label for this gene is dgdR [H]

Identifier: 17545334

GI number: 17545334

Start: 662013

End: 662882

Strand: Direct

Name: dgdR [H]

Synonym: RSc0615

Alternate gene names: 17545334

Gene position: 662013-662882 (Clockwise)

Preceding gene: 17545331

Following gene: 17545337

Centisome position: 17.81

GC content: 68.28

Gene sequence:

>870_bases
ATGACACCGCAAGATCTGCAGCTGGATTGGCTCAAGTGCTTCGTCGCCGTGGTGGACGCGGGTTCGCTGTCGAGTGCGGC
AGGGGAGGTGCACCGCTCCCAGTCGGCGGTCAGCATGCAGCTCAAGAAGCTCGAGGGCGCACTGGGGAGCCGGCTCCTCG
AGCGGGATGCGCGCAAGCTTGAGCTGACCCCCGAGGGGCAGATGCTGCTCGGCTATGCGCGGCGCATCCTCGATCTGCAT
GCCGAAGCCCAGGCCGCGCTCAGCGGCGAGGAACTCACCGGCCGGGTGCGGCTTGGCGTGCCTGACGACTACGCGGCCAA
GTACCTGACGCCGGTGCTCAAGCGCTTTGCGCCCAGGCACGGCGGCGTCGAGATCGAATTGGACTGCGAGCAGTCGACCT
CGCTCATTCCGCGTGTGGCCAGCGGCGACCTTGACCTCGCCCTGGTGTCCCGCGATCACTCACGGCGCGGCATCCTGCTG
TTTCACGAGCCGATGGTCTGGGTGGGCGCCGTGCAGTTCGAGCTGTGGCGGCGGGACCCGCTGCCGATCGCCGTCTACGA
AGACACCAGCCTGGCGCGGCGCAGCGCGATCCACTCCCTGGCGCAGCAAGGACGCCGATACAAGGTGGTCTACAACAGCT
CCAGCCTGGCGGGGCAGATTGCCGCCGTCGAGAGCGGCCTGGCGGTGGCGGCGCTGACCCAATGCAGCGCACCCGGGCAC
CTGCAGATCCTGGGCAGCGAGCACGGATTGGGGCCACTCGAACCCATGGAAGTGGCCGTCTACCGCAGCCGCGCCTCGCG
CGGCTCGAAAGCGGTGGACAGCCTGCAGAACCTGCTGGTCAGGACGCTGAGGTTGTCGGGGCCGATCTGA

Upstream 100 bases:

>100_bases
GGGTTCGTATTCATGGCGGCAGTGTGTACCGCCATCGATTCGACGAGAAGCGCATAATTCTGGGATCAATCATTCGATAA
TCGAAAGCGGAAAGAACCGG

Downstream 100 bases:

>100_bases
GGCGGAGTTGGGTGCCGAGAAAGGGGCGATGGCGGGGCTCGTGATCGATGCCGCGAGGCTTGCCGAGCCGGTCGTTCTAC
TCGATGCCATGGCGAGTGAT

Product: transcription regulator protein

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTPQDLQLDWLKCFVAVVDAGSLSSAAGEVHRSQSAVSMQLKKLEGALGSRLLERDARKLELTPEGQMLLGYARRILDLH
AEAQAALSGEELTGRVRLGVPDDYAAKYLTPVLKRFAPRHGGVEIELDCEQSTSLIPRVASGDLDLALVSRDHSRRGILL
FHEPMVWVGAVQFELWRRDPLPIAVYEDTSLARRSAIHSLAQQGRRYKVVYNSSSLAGQIAAVESGLAVAALTQCSAPGH
LQILGSEHGLGPLEPMEVAVYRSRASRGSKAVDSLQNLLVRTLRLSGPI

Sequences:

>Translated_289_residues
MTPQDLQLDWLKCFVAVVDAGSLSSAAGEVHRSQSAVSMQLKKLEGALGSRLLERDARKLELTPEGQMLLGYARRILDLH
AEAQAALSGEELTGRVRLGVPDDYAAKYLTPVLKRFAPRHGGVEIELDCEQSTSLIPRVASGDLDLALVSRDHSRRGILL
FHEPMVWVGAVQFELWRRDPLPIAVYEDTSLARRSAIHSLAQQGRRYKVVYNSSSLAGQIAAVESGLAVAALTQCSAPGH
LQILGSEHGLGPLEPMEVAVYRSRASRGSKAVDSLQNLLVRTLRLSGPI
>Mature_288_residues
TPQDLQLDWLKCFVAVVDAGSLSSAAGEVHRSQSAVSMQLKKLEGALGSRLLERDARKLELTPEGQMLLGYARRILDLHA
EAQAALSGEELTGRVRLGVPDDYAAKYLTPVLKRFAPRHGGVEIELDCEQSTSLIPRVASGDLDLALVSRDHSRRGILLF
HEPMVWVGAVQFELWRRDPLPIAVYEDTSLARRSAIHSLAQQGRRYKVVYNSSSLAGQIAAVESGLAVAALTQCSAPGHL
QILGSEHGLGPLEPMEVAVYRSRASRGSKAVDSLQNLLVRTLRLSGPI

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=254, Percent_Identity=31.1023622047244, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787806, Length=248, Percent_Identity=27.8225806451613, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790262, Length=161, Percent_Identity=32.2981366459627, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788297, Length=238, Percent_Identity=30.672268907563, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790399, Length=244, Percent_Identity=27.8688524590164, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI157672245, Length=188, Percent_Identity=28.7234042553192, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI145693193, Length=119, Percent_Identity=31.9327731092437, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786401, Length=131, Percent_Identity=35.8778625954198, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790208, Length=153, Percent_Identity=28.7581699346405, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788887, Length=257, Percent_Identity=26.8482490272374, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786448, Length=142, Percent_Identity=29.5774647887324, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31431; Mature: 31300

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPQDLQLDWLKCFVAVVDAGSLSSAAGEVHRSQSAVSMQLKKLEGALGSRLLERDARKL
CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
ELTPEGQMLLGYARRILDLHAEAQAALSGEELTGRVRLGVPDDYAAKYLTPVLKRFAPRH
EECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCC
GGVEIELDCEQSTSLIPRVASGDLDLALVSRDHSRRGILLFHEPMVWVGAVQFELWRRDP
CCEEEEEECCCCCCCCCEECCCCCEEEEEECCCCCCCEEEEECCCEEHHHHEEEEECCCC
LPIAVYEDTSLARRSAIHSLAQQGRRYKVVYNSSSLAGQIAAVESGLAVAALTQCSAPGH
CCEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEEHHHHCCCCCE
LQILGSEHGLGPLEPMEVAVYRSRASRGSKAVDSLQNLLVRTLRLSGPI
EEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TPQDLQLDWLKCFVAVVDAGSLSSAAGEVHRSQSAVSMQLKKLEGALGSRLLERDARKL
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
ELTPEGQMLLGYARRILDLHAEAQAALSGEELTGRVRLGVPDDYAAKYLTPVLKRFAPRH
EECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCC
GGVEIELDCEQSTSLIPRVASGDLDLALVSRDHSRRGILLFHEPMVWVGAVQFELWRRDP
CCEEEEEECCCCCCCCCEECCCCCEEEEEECCCCCCCEEEEECCCEEHHHHEEEEECCCC
LPIAVYEDTSLARRSAIHSLAQQGRRYKVVYNSSSLAGQIAAVESGLAVAALTQCSAPGH
CCEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEEHHHHCCCCCE
LQILGSEHGLGPLEPMEVAVYRSRASRGSKAVDSLQNLLVRTLRLSGPI
EEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]