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The map label for this gene is gph [C]

Identifier: 17545300

GI number: 17545300

Start: 624749

End: 625450

Strand: Reverse

Name: gph [C]

Synonym: RSc0581

Alternate gene names: 17545300

Gene position: 625450-624749 (Counterclockwise)

Preceding gene: 17545301

Following gene: 17545298

Centisome position: 16.83

GC content: 62.82

Gene sequence:

>702_bases
ATGCCCAATATGTCCACCCATTTCCATCATCAGCCGGTAGAGGCGTTCATCATCGATCTCGATGGAACGATGGTCGACAC
CATCGACGATCTGGCCATCGCGTTCAATACCGCCCTGAACCAGCTGGGGCTGGCGCCTGTCGCGACGGCATTCGTGGAGC
GGATGATCAACAAGGGGCCCGAACACCTTGTGCGCGCGGCGCTCGGCGATGCCGGTACCGACATGGCGCTCTACGAGCGC
TGCCTGCAGCTGTATAGAAAGGCCTATGGCGAGATCAACGGCAAATATGCTCGCGTCTATCCCGGCGTCGGGGAGAGCCT
GGCGGAACTCCGGGCCCTCGGGATGAAACTCGCCTGCCTGACCAACAAGCCGGGTTCGTTCGCACGTGCATTGCTCAAGG
AGAAACAGCTCGATGGCTTCTTCAGCGTGGTGTTCGGGGGAGACGCCTTCCCGTGCCAGAAACCCGATCCGCTGCCGGTC
ATCAGGACATGCGAGGCACTCGGTACCGCGCCGTCCCGGACGCTGATGGTCGGGGACTCGAACAACGACGCGCTGGCCGC
GAAGGCGGCCGGCTGCCGGGTCGTGCTGGTGAAGTACGGGTATCACCATGGTGAATCCCGCAGCCGCACCCACGTCGATG
GCGTCATTGACGGCCTGCATCAACTGCGGCCGTTCTGCCGTCTTGCCGATCAGGACGCGTGA

Upstream 100 bases:

>100_bases
AATGATTATTGGCGCAGCGCCGATGTATTCTGCATCTTCTGCAATACCAATATCGTTTGCCGGGTCGCGCACAAACTCTG
AATGCAATCGGGTTCATGCC

Downstream 100 bases:

>100_bases
CCACCGGAATCCCCTTCGTGGAGACGAACGCGGTTGCATGACCGTGGCGCCCGATACGGGTCGGAGCACCAGCGGTCCGT
CCAGTTGCGCCCCCCGAAAG

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MPNMSTHFHHQPVEAFIIDLDGTMVDTIDDLAIAFNTALNQLGLAPVATAFVERMINKGPEHLVRAALGDAGTDMALYER
CLQLYRKAYGEINGKYARVYPGVGESLAELRALGMKLACLTNKPGSFARALLKEKQLDGFFSVVFGGDAFPCQKPDPLPV
IRTCEALGTAPSRTLMVGDSNNDALAAKAAGCRVVLVKYGYHHGESRSRTHVDGVIDGLHQLRPFCRLADQDA

Sequences:

>Translated_233_residues
MPNMSTHFHHQPVEAFIIDLDGTMVDTIDDLAIAFNTALNQLGLAPVATAFVERMINKGPEHLVRAALGDAGTDMALYER
CLQLYRKAYGEINGKYARVYPGVGESLAELRALGMKLACLTNKPGSFARALLKEKQLDGFFSVVFGGDAFPCQKPDPLPV
IRTCEALGTAPSRTLMVGDSNNDALAAKAAGCRVVLVKYGYHHGESRSRTHVDGVIDGLHQLRPFCRLADQDA
>Mature_232_residues
PNMSTHFHHQPVEAFIIDLDGTMVDTIDDLAIAFNTALNQLGLAPVATAFVERMINKGPEHLVRAALGDAGTDMALYERC
LQLYRKAYGEINGKYARVYPGVGESLAELRALGMKLACLTNKPGSFARALLKEKQLDGFFSVVFGGDAFPCQKPDPLPVI
RTCEALGTAPSRTLMVGDSNNDALAAKAAGCRVVLVKYGYHHGESRSRTHVDGVIDGLHQLRPFCRLADQDA

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=231, Percent_Identity=33.7662337662338, Blast_Score=124, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 25273; Mature: 25142

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNMSTHFHHQPVEAFIIDLDGTMVDTIDDLAIAFNTALNQLGLAPVATAFVERMINKGP
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCH
EHLVRAALGDAGTDMALYERCLQLYRKAYGEINGKYARVYPGVGESLAELRALGMKLACL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHEEEE
TNKPGSFARALLKEKQLDGFFSVVFGGDAFPCQKPDPLPVIRTCEALGTAPSRTLMVGDS
CCCCHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECC
NNDALAAKAAGCRVVLVKYGYHHGESRSRTHVDGVIDGLHQLRPFCRLADQDA
CCCEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PNMSTHFHHQPVEAFIIDLDGTMVDTIDDLAIAFNTALNQLGLAPVATAFVERMINKGP
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCH
EHLVRAALGDAGTDMALYERCLQLYRKAYGEINGKYARVYPGVGESLAELRALGMKLACL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHEEEE
TNKPGSFARALLKEKQLDGFFSVVFGGDAFPCQKPDPLPVIRTCEALGTAPSRTLMVGDS
CCCCHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECC
NNDALAAKAAGCRVVLVKYGYHHGESRSRTHVDGVIDGLHQLRPFCRLADQDA
CCCEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA