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The map label for this gene is lnt

Identifier: 17545246

GI number: 17545246

Start: 565208

End: 566779

Strand: Reverse

Name: lnt

Synonym: RSc0527

Alternate gene names: 17545246

Gene position: 566779-565208 (Counterclockwise)

Preceding gene: 17545247

Following gene: 17545245

Centisome position: 15.25

GC content: 71.82

Gene sequence:

>1572_bases
GTGCGCGCTTTGTTCTCCTCTCCTGCCGCCGACACCGCTGGCCAGCAGGAAGCCCTGGCCGTGCCGCTTGCCCGGCTGCG
CTTTGCCGCGCCGCTGGCGGCGCTGCTGGGTGTCATGCATACGCTGGCCTTCGCGCCCAACCGCTGGTGGTGGCTGCAGA
TCCTGTCGCTGGCCGGGCTGGCGGCGCTGGTCCGGCAGGCACCGCGCCTGCGCGACGTGGCCTGGGTCGGCTACGCCTTC
GGGCTGGGCTGGTTCCTGTCGGGCATCTGGTGGCTGTACATCAGCATGCACGTCTACGGCGACATGCCGGCATGGATGGC
CGCGGCCGCCGTGCTGCTGTTCTCGGCCTACCTGGCCCTGCACCCGGCGCTCGCGGCATGGCTGTGGCAGCGCCTCGCGC
GCGGCCGGCAGTTGTCCGGCGCGGCCAGCGCGCTCGTGTTCGGCGCGGCGTGGCTCGTCTCGGAATGGCTGCGCGGCACG
GAATGGACGGGCTTCCCCTGGCTCAACGGCGGTTATGCCCACACCGACGGTCCGCTGGCCGGCTATGCGCCGCTGGTCGG
CGTGTATGGCGTCGTCGCGATCGCCGCGACGCTGGCCGGCCTGCTGTGCGCGGCCGCCGAGCGCCGGCTGCACTGGCTGG
CCGGGCTCGCGGGCGTGGCCGTGCTGGCGGCCGGCTGGCCGCTGCACACCATCGCGTGGACCCAGCCGGTGGGCAAGCCG
ATCACCGTGCGGCTGCTGCAGGGCAACGTGCCGCAGGACGTGAAGTTCCAGCAGACCGGCATCGACCATTCGCTGGCGCT
GTACACCAAGATGGTGACCGAGCAGCCCGCCCAGTTGGTGGTGACGCCCGAGACGGCCTTCCCGATCCTGCTCCAGGACA
TGCCGCAGGAGATCGCGCTGGCCATCCGCACCTATGTGGACACGACCGGCTCCAGCGTGCTGTTCGGCGCGGCCAACGCG
GATTCGGCAGTGGACTACACCAACAGCGCGTTCGGCGTCGGCCCGTGGTTCAAGGGGGTGTATCGCTACGACAAGCACCA
CCTCGTGCCCTTCGGCGAATTCATCCCGTTCGGCTTCCACTGGTTCGTCCACATGATGAACATGCCGCTCGGCGACTTCC
GCCGCGGCCTGCCGGTGCAGCCGCCCATGCCGGTGGCCGGCCAGCGCGTCGCGCCCAACATCTGCTACGAGGACTTGTTC
GGCGAGGAGATCGCCGCATCGCTGCGCCAGGCGGAACGGCCGGCCACGATGCTCGCCAACGTGACCAACCTGGCCTGGTT
CGGCGACACCATCGCGCTGGACCAGCACCTGCAGATCTCGCGCATGCGGGCCCTGGAGAGCGGCCGGCCGATGCTGCGCG
CGACCAACACCGGCGCCACCGCCGTGGTGCGTCCGGACGGCAGCGTGCAGGCGCGGCTGCCCGTGTTCACGCTCGGCACG
CTGCAGGCCGACGTGCAGGGCATGCAGGGCCTGACGCCGTTCGTGCGGACCGGCAACGCGCCCGCGCTGGGCGCCGGTGT
GCTGGTGCTGCTGGCCGCGCTGGCGCGCCGCCGCCGCGCCGGAGCGGCGTAA

Upstream 100 bases:

>100_bases
GTGCTGCTGGTGCGCCACCTCGCCGCACCCGCGCCGGGCGCCGCCGCCCCGGCCGACCCGTCCCGCTCCAACCCCGCCTG
ATCGCCTGAGTTCGTTTTCC

Downstream 100 bases:

>100_bases
CCCGGCCCCGTCCGGCGGCTTTTCGCGCACTTTGCGGGACGCTGGACAAAAAACGCTAAAATTCAACGTTTTACGGCGGG
GCGCCCAGGCACCCCGCCGC

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MRALFSSPAADTAGQQEALAVPLARLRFAAPLAALLGVMHTLAFAPNRWWWLQILSLAGLAALVRQAPRLRDVAWVGYAF
GLGWFLSGIWWLYISMHVYGDMPAWMAAAAVLLFSAYLALHPALAAWLWQRLARGRQLSGAASALVFGAAWLVSEWLRGT
EWTGFPWLNGGYAHTDGPLAGYAPLVGVYGVVAIAATLAGLLCAAAERRLHWLAGLAGVAVLAAGWPLHTIAWTQPVGKP
ITVRLLQGNVPQDVKFQQTGIDHSLALYTKMVTEQPAQLVVTPETAFPILLQDMPQEIALAIRTYVDTTGSSVLFGAANA
DSAVDYTNSAFGVGPWFKGVYRYDKHHLVPFGEFIPFGFHWFVHMMNMPLGDFRRGLPVQPPMPVAGQRVAPNICYEDLF
GEEIAASLRQAERPATMLANVTNLAWFGDTIALDQHLQISRMRALESGRPMLRATNTGATAVVRPDGSVQARLPVFTLGT
LQADVQGMQGLTPFVRTGNAPALGAGVLVLLAALARRRRAGAA

Sequences:

>Translated_523_residues
MRALFSSPAADTAGQQEALAVPLARLRFAAPLAALLGVMHTLAFAPNRWWWLQILSLAGLAALVRQAPRLRDVAWVGYAF
GLGWFLSGIWWLYISMHVYGDMPAWMAAAAVLLFSAYLALHPALAAWLWQRLARGRQLSGAASALVFGAAWLVSEWLRGT
EWTGFPWLNGGYAHTDGPLAGYAPLVGVYGVVAIAATLAGLLCAAAERRLHWLAGLAGVAVLAAGWPLHTIAWTQPVGKP
ITVRLLQGNVPQDVKFQQTGIDHSLALYTKMVTEQPAQLVVTPETAFPILLQDMPQEIALAIRTYVDTTGSSVLFGAANA
DSAVDYTNSAFGVGPWFKGVYRYDKHHLVPFGEFIPFGFHWFVHMMNMPLGDFRRGLPVQPPMPVAGQRVAPNICYEDLF
GEEIAASLRQAERPATMLANVTNLAWFGDTIALDQHLQISRMRALESGRPMLRATNTGATAVVRPDGSVQARLPVFTLGT
LQADVQGMQGLTPFVRTGNAPALGAGVLVLLAALARRRRAGAA
>Mature_523_residues
MRALFSSPAADTAGQQEALAVPLARLRFAAPLAALLGVMHTLAFAPNRWWWLQILSLAGLAALVRQAPRLRDVAWVGYAF
GLGWFLSGIWWLYISMHVYGDMPAWMAAAAVLLFSAYLALHPALAAWLWQRLARGRQLSGAASALVFGAAWLVSEWLRGT
EWTGFPWLNGGYAHTDGPLAGYAPLVGVYGVVAIAATLAGLLCAAAERRLHWLAGLAGVAVLAAGWPLHTIAWTQPVGKP
ITVRLLQGNVPQDVKFQQTGIDHSLALYTKMVTEQPAQLVVTPETAFPILLQDMPQEIALAIRTYVDTTGSSVLFGAANA
DSAVDYTNSAFGVGPWFKGVYRYDKHHLVPFGEFIPFGFHWFVHMMNMPLGDFRRGLPVQPPMPVAGQRVAPNICYEDLF
GEEIAASLRQAERPATMLANVTNLAWFGDTIALDQHLQISRMRALESGRPMLRATNTGATAVVRPDGSVQARLPVFTLGT
LQADVQGMQGLTPFVRTGNAPALGAGVLVLLAALARRRRAGAA

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=521, Percent_Identity=37.0441458733205, Blast_Score=279, Evalue=4e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT_RALSO (Q8Y210)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_518648.1
- ProteinModelPortal:   Q8Y210
- GeneID:   1219331
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc0527
- NMPDR:   fig|267608.1.peg.527
- HOGENOM:   HBG616234
- OMA:   IAPYICY
- ProtClustDB:   PRK00302
- BioCyc:   RSOL267608:RSC0527-MONOMER
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 56513; Mature: 56513

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13fd1994)-; HASH(0x13b23e84)-; HASH(0x13726a14)-; HASH(0x142cedb4)-; HASH(0x13ac1568)-; HASH(0x134118dc)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure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HHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852