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The map label for this gene is glyQ

Identifier: 17545245

GI number: 17545245

Start: 564077

End: 565054

Strand: Reverse

Name: glyQ

Synonym: RSc0526

Alternate gene names: 17545245

Gene position: 565054-564077 (Counterclockwise)

Preceding gene: 17545246

Following gene: 17545244

Centisome position: 15.2

GC content: 68.2

Gene sequence:

>978_bases
ATGCTCACCTTCCAGCAACTCATCCTCAAGCTGCAGTCGTACTGGGACGCCCAGGGCTGCGCGCTGCTGCAGCCGATCGA
CCTCGAAGTCGGTGCCGGCACCTCGCACGTCCACACCTTCCTGCGCGCCATCGGCCCGGAGCCGTGGCGCGCCGCCTACG
TGCAGCCGTCGCGCCGTCCCAAGGACGGCCGCTACGGCGAGAACCCCAACCGCCTGCAGCACTACTACCAGTACCAGGTG
GTGCTCAAGCCCGCGCCCGAGAACATCCTCGACCTATACCTCGGCTCGCTCCAGGCGCTAGGGCTGGACCTCAAGCAGAA
CGACGTGCGCTTCGTCGAGGACGACTGGGAAAACCCCACGCTCGGCGCCTGGGGCCTGGGCTGGGAAGTCTGGCTCAACG
GCATGGAAGTCACGCAGTTCACCTACTTCCAGCAGGTCGGCGGCCTCGACTGCAAGCCCATCACGGGCGAAATCACCTAC
GGCATCGAGCGCCTGGCGATGTACCTGCAGCAGGTCGAGAACGTCTACGACCTGGTCTGGACGGAGTGGGAAGAACCGGG
CCCCAACGGCCCCGTCAAGCGCCGCCTGACCTACGGCGACGTCTATCACCAGAACGAAGTCGAGCAGTCGACGTACAACT
TCGAGCACGCGGATACGGCCGTGCTGTTCCGCCGCTTCGCAGAACACGAGGCGGAGGCCAAGCGCCTGATGGGCGTGCGC
GAAGAAGGCGCGGCCGACGACGGCGCAGCGGTGCCGCAGCTGGCGCTGCCCGCCTACGAGCAGGTGCTCAAGGCCGGCCA
CACCTTCAACCTGCTGGACGCGCGCGGCGCCATCTCGGTGACCGAGCGCGCCGCCTACATCGGCCGCATCCGCAACCTGT
CGCGGCTGGTGGCGCAGGCCTACTACGACTCGCGCGAGCGCCTGGGCTTCCCGATGTGCGGCACGGCCGCGGCGCCGGCG
GCCACGGAGGCCGCATGA

Upstream 100 bases:

>100_bases
CGCTAAAATTCAACGTTTTACGGCGGGGCGCCCAGGCACCCCGCCGCTGCATTCGACCGCCGCGCGGCGGCCTCCTCCGC
GCCGGACCCTCGGGATCACC

Downstream 100 bases:

>100_bases
CGCTCGCTCGCGCCCGGCGCGGCCTGGCCCTGCTGATGGCCGCCGCGCTGACCCTGCCCGCGGGGATCGCGCAGGCACGG
CACCATCGGGCCGCCCGGCC

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MLTFQQLILKLQSYWDAQGCALLQPIDLEVGAGTSHVHTFLRAIGPEPWRAAYVQPSRRPKDGRYGENPNRLQHYYQYQV
VLKPAPENILDLYLGSLQALGLDLKQNDVRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLDCKPITGEITY
GIERLAMYLQQVENVYDLVWTEWEEPGPNGPVKRRLTYGDVYHQNEVEQSTYNFEHADTAVLFRRFAEHEAEAKRLMGVR
EEGAADDGAAVPQLALPAYEQVLKAGHTFNLLDARGAISVTERAAYIGRIRNLSRLVAQAYYDSRERLGFPMCGTAAAPA
ATEAA

Sequences:

>Translated_325_residues
MLTFQQLILKLQSYWDAQGCALLQPIDLEVGAGTSHVHTFLRAIGPEPWRAAYVQPSRRPKDGRYGENPNRLQHYYQYQV
VLKPAPENILDLYLGSLQALGLDLKQNDVRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLDCKPITGEITY
GIERLAMYLQQVENVYDLVWTEWEEPGPNGPVKRRLTYGDVYHQNEVEQSTYNFEHADTAVLFRRFAEHEAEAKRLMGVR
EEGAADDGAAVPQLALPAYEQVLKAGHTFNLLDARGAISVTERAAYIGRIRNLSRLVAQAYYDSRERLGFPMCGTAAAPA
ATEAA
>Mature_325_residues
MLTFQQLILKLQSYWDAQGCALLQPIDLEVGAGTSHVHTFLRAIGPEPWRAAYVQPSRRPKDGRYGENPNRLQHYYQYQV
VLKPAPENILDLYLGSLQALGLDLKQNDVRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLDCKPITGEITY
GIERLAMYLQQVENVYDLVWTEWEEPGPNGPVKRRLTYGDVYHQNEVEQSTYNFEHADTAVLFRRFAEHEAEAKRLMGVR
EEGAADDGAAVPQLALPAYEQVLKAGHTFNLLDARGAISVTERAAYIGRIRNLSRLVAQAYYDSRERLGFPMCGTAAAPA
ATEAA

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=311, Percent_Identity=68.1672025723473, Blast_Score=438, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_RALSO (Q8Y211)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_518647.1
- ProteinModelPortal:   Q8Y211
- SMR:   Q8Y211
- GeneID:   1219330
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc0526
- NMPDR:   fig|267608.1.peg.526
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- ProtClustDB:   PRK09348
- BioCyc:   RSOL267608:RSC0526-MONOMER
- BRENDA:   6.1.1.14
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 36673; Mature: 36673

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTFQQLILKLQSYWDAQGCALLQPIDLEVGAGTSHVHTFLRAIGPEPWRAAYVQPSRRP
CCCHHHHHHHHHHHCCCCCCEEECCCCEEECCCHHHHHHHHHHHCCCCCEEECCCCCCCC
KDGRYGENPNRLQHYYQYQVVLKPAPENILDLYLGSLQALGLDLKQNDVRFVEDDWENPT
CCCCCCCCHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCC
LGAWGLGWEVWLNGMEVTQFTYFQQVGGLDCKPITGEITYGIERLAMYLQQVENVYDLVW
CCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TEWEEPGPNGPVKRRLTYGDVYHQNEVEQSTYNFEHADTAVLFRRFAEHEAEAKRLMGVR
HCCCCCCCCCCHHEEEECCHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
EEGAADDGAAVPQLALPAYEQVLKAGHTFNLLDARGAISVTERAAYIGRIRNLSRLVAQA
HCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
YYDSRERLGFPMCGTAAAPAATEAA
HHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLTFQQLILKLQSYWDAQGCALLQPIDLEVGAGTSHVHTFLRAIGPEPWRAAYVQPSRRP
CCCHHHHHHHHHHHCCCCCCEEECCCCEEECCCHHHHHHHHHHHCCCCCEEECCCCCCCC
KDGRYGENPNRLQHYYQYQVVLKPAPENILDLYLGSLQALGLDLKQNDVRFVEDDWENPT
CCCCCCCCHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCC
LGAWGLGWEVWLNGMEVTQFTYFQQVGGLDCKPITGEITYGIERLAMYLQQVENVYDLVW
CCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TEWEEPGPNGPVKRRLTYGDVYHQNEVEQSTYNFEHADTAVLFRRFAEHEAEAKRLMGVR
HCCCCCCCCCCHHEEEECCHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
EEGAADDGAAVPQLALPAYEQVLKAGHTFNLLDARGAISVTERAAYIGRIRNLSRLVAQA
HCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
YYDSRERLGFPMCGTAAAPAATEAA
HHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852