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The map label for this gene is erpA [H]

Identifier: 17545213

GI number: 17545213

Start: 529814

End: 530188

Strand: Direct

Name: erpA [H]

Synonym: RSc0494

Alternate gene names: 17545213

Gene position: 529814-530188 (Clockwise)

Preceding gene: 17545212

Following gene: 17545215

Centisome position: 14.26

GC content: 58.93

Gene sequence:

>375_bases
ATGAACGCAGTCGCGCAGGCAGCCACGCCCGATGTGAACGAGGTTCCGGCTCCGCTGGTCTTTACCGACAGCGCTGCGGA
CAAGGTCAAGCAACTGATCGAAGAGGAAGGCAATCCGGAGCTGAAGCTGCGCGTGTTCGTGCAAGGCGGCGGGTGCTCGG
GCTTCCAGTACGGCTTCACCTTTGACGAAGACACCAACGAAGACGACACGACCATGACCAAGAATGGCGTGACGCTTCTG
ATCGACTCGATGAGCTACCAGTACCTGGTGGGCGCCGAGATCGACTACAAGGAAGACATCAACGGTGCCCAGTTCGTCAT
CAAGAACCCGAATGCCTCGACCACCTGCGGTTGCGGTTCGTCGTTCTCGGTCTGA

Upstream 100 bases:

>100_bases
GCACCGCACAATGTCCTCTTGAAAGCTGGGGCTTCGGCACGATTTACCGTCTGCGCTTAAAATAGCAGCAGATTTGAGAC
GTTCCCACAGGAGATTTTTC

Downstream 100 bases:

>100_bases
AACCGGCATCGACAAAAGAAAAAGCGCACTTCGGTGCGCTTTTTTGTTGCCCATTGCCACCGTCTAGGCCGGATAGATCG
TGCCCAGCACGCGGGGGCCG

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MNAVAQAATPDVNEVPAPLVFTDSAADKVKQLIEEEGNPELKLRVFVQGGGCSGFQYGFTFDEDTNEDDTTMTKNGVTLL
IDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSFSV

Sequences:

>Translated_124_residues
MNAVAQAATPDVNEVPAPLVFTDSAADKVKQLIEEEGNPELKLRVFVQGGGCSGFQYGFTFDEDTNEDDTTMTKNGVTLL
IDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSFSV
>Mature_124_residues
MNAVAQAATPDVNEVPAPLVFTDSAADKVKQLIEEEGNPELKLRVFVQGGGCSGFQYGFTFDEDTNEDDTTMTKNGVTLL
IDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSFSV

Specific function: Required for insertion of 4Fe-4S clusters (Potential) [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=121, Percent_Identity=38.0165289256198, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI52426768, Length=109, Percent_Identity=36.697247706422, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1786351, Length=112, Percent_Identity=61.6071428571429, Blast_Score=155, Evalue=1e-39,
Organism=Escherichia coli, GI1788877, Length=107, Percent_Identity=35.5140186915888, Blast_Score=67, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71998452, Length=105, Percent_Identity=39.0476190476191, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25146411, Length=113, Percent_Identity=31.858407079646, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193209025, Length=108, Percent_Identity=32.4074074074074, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=97, Percent_Identity=38.1443298969072, Blast_Score=75, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=46.9879518072289, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24642263, Length=109, Percent_Identity=33.9449541284404, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 13304; Mature: 13304

Theoretical pI: Translated: 3.80; Mature: 3.80

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVAQAATPDVNEVPAPLVFTDSAADKVKQLIEEEGNPELKLRVFVQGGGCSGFQYGFT
CCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEE
FDEDTNEDDTTMTKNGVTLLIDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGS
ECCCCCCCCCEEECCCEEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCCCCCEECCCC
SFSV
CCCC
>Mature Secondary Structure
MNAVAQAATPDVNEVPAPLVFTDSAADKVKQLIEEEGNPELKLRVFVQGGGCSGFQYGFT
CCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEE
FDEDTNEDDTTMTKNGVTLLIDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGS
ECCCCCCCCCEEECCCEEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCCCCCEECCCC
SFSV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA