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The map label for this gene is kdsC [H]

Identifier: 17545131

GI number: 17545131

Start: 439256

End: 439843

Strand: Reverse

Name: kdsC [H]

Synonym: RSc0412

Alternate gene names: 17545131

Gene position: 439843-439256 (Counterclockwise)

Preceding gene: 17545132

Following gene: 17545130

Centisome position: 11.84

GC content: 70.58

Gene sequence:

>588_bases
ATGTCCAGCCCGGCCGATTCCCCCGTCCACAGCAACATCGAGGCACGCTTCCCGCAGGCAATGGAGCGCGCCGCCCGCGT
GCGCCTGATGATCTTCGACGTGGACGGCGTGCTGACCGACGGCCGCCTGCTGGTCGGCCCGCAGGGCGAGATCAGCAAGG
CCTTCGATACGCTGGACGGCCACGGCATCAAGCTGCTGGCCCAGGCGGGCATTACGCCGGCCATCATCACCGGGCGCGAA
TCCGAGATCGTGGCCTGGCGCGCCGGGGAACTCGGCATCGAACATCTGTACCAAGGTGTGGCCGACAAGCGCGAGGCCTT
CGTCCACCTGCTTGCCGCCACAGCGCTGCAGCCCGCCGACGCCGGCTACATGGGCGACGACTGGCCCGACCTGCCGGTCA
TGGCGCAGGTCGGCTTTGCCGCCTGCCCCGCCCAGGCCCACGCCGAGGTGCGCAGCCGCTGCCACTATGTGACCCGGGCC
AAGGGCGGTCGCGGCGCGGCGCGTGAAGTCGCCGACCTGATCCTCAAGGCCCAGGGCGCCTACGACGACCTGCTCGCGCA
ACTGCTGCAAGCGCCCAACGCCCCCTGA

Upstream 100 bases:

>100_bases
CCGCCGGGCAGCTGATGGGCGCGCTGCACATCCACGACCTGACCCGCGCCAAGGTCATCTGAGTCTGATTCCGCTGCTCC
GACACCCCGACGCCCCGCCG

Downstream 100 bases:

>100_bases
CATGGCCAGCGAACGCTCTCAACGCCTCGTCTCCTCCCTGCTGCAGATCATGCTGCGCGGGTTGCCCATCCTGCTGATGG
CGGTGGTATGCGGCGTCACC

Product: hypothetical protein

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MSSPADSPVHSNIEARFPQAMERAARVRLMIFDVDGVLTDGRLLVGPQGEISKAFDTLDGHGIKLLAQAGITPAIITGRE
SEIVAWRAGELGIEHLYQGVADKREAFVHLLAATALQPADAGYMGDDWPDLPVMAQVGFAACPAQAHAEVRSRCHYVTRA
KGGRGAAREVADLILKAQGAYDDLLAQLLQAPNAP

Sequences:

>Translated_195_residues
MSSPADSPVHSNIEARFPQAMERAARVRLMIFDVDGVLTDGRLLVGPQGEISKAFDTLDGHGIKLLAQAGITPAIITGRE
SEIVAWRAGELGIEHLYQGVADKREAFVHLLAATALQPADAGYMGDDWPDLPVMAQVGFAACPAQAHAEVRSRCHYVTRA
KGGRGAAREVADLILKAQGAYDDLLAQLLQAPNAP
>Mature_194_residues
SSPADSPVHSNIEARFPQAMERAARVRLMIFDVDGVLTDGRLLVGPQGEISKAFDTLDGHGIKLLAQAGITPAIITGRES
EIVAWRAGELGIEHLYQGVADKREAFVHLLAATALQPADAGYMGDDWPDLPVMAQVGFAACPAQAHAEVRSRCHYVTRAK
GGRGAAREVADLILKAQGAYDDLLAQLLQAPNAP

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=154, Percent_Identity=29.2207792207792, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI2367202, Length=163, Percent_Identity=48.4662576687117, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 20775; Mature: 20644

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPADSPVHSNIEARFPQAMERAARVRLMIFDVDGVLTDGRLLVGPQGEISKAFDTLDG
CCCCCCCCCCCCHHHCCHHHHHHHHHEEEEEEECCCEEECCEEEECCCCHHHHHHHCCCC
HGIKLLAQAGITPAIITGRESEIVAWRAGELGIEHLYQGVADKREAFVHLLAATALQPAD
CCEEEEECCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGYMGDDWPDLPVMAQVGFAACPAQAHAEVRSRCHYVTRAKGGRGAAREVADLILKAQGA
CCCCCCCCCCCCHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
YDDLLAQLLQAPNAP
HHHHHHHHHHCCCCC
>Mature Secondary Structure 
SSPADSPVHSNIEARFPQAMERAARVRLMIFDVDGVLTDGRLLVGPQGEISKAFDTLDG
CCCCCCCCCCCHHHCCHHHHHHHHHEEEEEEECCCEEECCEEEECCCCHHHHHHHCCCC
HGIKLLAQAGITPAIITGRESEIVAWRAGELGIEHLYQGVADKREAFVHLLAATALQPAD
CCEEEEECCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGYMGDDWPDLPVMAQVGFAACPAQAHAEVRSRCHYVTRAKGGRGAAREVADLILKAQGA
CCCCCCCCCCCCHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
YDDLLAQLLQAPNAP
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]