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The map label for this gene is 17545107

Identifier: 17545107

GI number: 17545107

Start: 416629

End: 417972

Strand: Direct

Name: 17545107

Synonym: RSc0388

Alternate gene names: NA

Gene position: 416629-417972 (Clockwise)

Preceding gene: 17545106

Following gene: 17545108

Centisome position: 11.21

GC content: 71.28

Gene sequence:

>1344_bases
ATGCGCGCCATGTCCCTGACCCTGAAGACGTTCCTGGCCGGCATGCTGGCCGCCGCGGCGCACGGTGCGCTGGCCGCGCT
GCCGATCGAGCACTGGACGGCCGCCACCGGCGCACGCGTGTTCTTCGTGCCGAGCCCGTCGATCCCGATGCTCGATATCA
ACCTCGATGTCGATGCCGGCACACGCTATGAGCCGGCGGCCAAGGTCGGTCTCGCCTCGCTCACGGCGGGCATGCTCGAC
AAGGGCGTCGCAGCCGTCGGCAGCACGCCGGCGCGCGACGAGGCGGCCATCGCCGATGCCTTTGCCGACGTGGGCGCCAG
CTTCTCGGGCGGCGCCGGCGGCGACCGCACCAGCCTGCGCCTGCGCACGCTGTCCGATCCGGCCGAGCGCAAGCCCGCGG
TGGACCTGATGGCGCAGATCGTCGCCGCGCCCACCGTGCCCGACGCCGTGCTGACGCGCGACAAGCAGCGCACGGTCGCC
GCCATCCGCGAGTCGCTGACCAAGCCCCAGGTGCTGGCCGACCGCGCCTTCGGCACGGCCATCTACGGCACGCACCCGTA
CGGCCAGTCGGCGACGCCCGACACGGTGCAGAGCATCACCCGCGACGACATCCTGCGCTTCTACCACGCCAACTACACCG
CCAAGCGCGCCGTGGTCACGCTGATTGGTGCGATCAGCCGGCAGGAGGCCGAGGCCATCGCCGAGCAGGTCACGCGCGGC
CTGCCGCCGGATGGCGCCACGCCGCCTGCGCTGCCCGCCGTCGATGCGCCGCTGGCCAAGGCCGACACCGTGCGCATTGC
GCACCCGGCGCAGCAGGCGACCATCGTGATGGGGCAGCCCGGCATCGCGCGCAGCGACAAGGACTACTTCCCGCTGCTGG
TCGGCAATTACGTGCTGGGCGGCGGCGGCTTCAGCTCGCGCCTGACCAACGAAGTCCGCGAGAAGCGCGGCCTGACCTAC
AGCATCGGCAGCTATTTCGCGCCGGCCGCGCAGCTTGGCCCGTTCGAACTGGCGCTGCAGACGCGCAAGGACCAGACCGA
GCAGGCGCTGACCGTGGTGCGCGACACCGTCGTCCGCTTTGTCGCCGAGGGCCCGACCGATGCCGAGCTCAAGGCCGCCA
AGGACAACCTCGTCAACGGTTTCCCGCTGCGCCTGGACAGCAACCGCAAGCTGCTGGACAACGTCGCCAACATCGCGTGG
TACAACCTGCCGCTCGACTACCTGGACACCTGGACGCAGCGCGTCGCGGCCGTCACGCGCGAGCAGGTGCGCGTCGCGTT
CCAGCGCGTGCTGCAGCCGCAGACCATGGCGACCATCGTGGTGGGCGGTCCGGCACCGCACTGA

Upstream 100 bases:

>100_bases
ACAACCTGGTCGTGGCGACACTGTTGCCGCAACCGATCGACCCGAACAAGCCGGCGCGCAAGCCCGTTCCCGGCATGCGC
GAAGAAGGAGGGCTGCGTTG

Downstream 100 bases:

>100_bases
CGGCCGGGTTGGCTCCCGAGCGCAAAAAACCGGCGGCATCCCCGCCGGTTTTTGTTTGCGCAGGCTCTACAATCGCGCCC
ATGGCTTCCCGTACTCCCAA

Product: Zinc protease-like signal peptide protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MRAMSLTLKTFLAGMLAAAAHGALAALPIEHWTAATGARVFFVPSPSIPMLDINLDVDAGTRYEPAAKVGLASLTAGMLD
KGVAAVGSTPARDEAAIADAFADVGASFSGGAGGDRTSLRLRTLSDPAERKPAVDLMAQIVAAPTVPDAVLTRDKQRTVA
AIRESLTKPQVLADRAFGTAIYGTHPYGQSATPDTVQSITRDDILRFYHANYTAKRAVVTLIGAISRQEAEAIAEQVTRG
LPPDGATPPALPAVDAPLAKADTVRIAHPAQQATIVMGQPGIARSDKDYFPLLVGNYVLGGGGFSSRLTNEVREKRGLTY
SIGSYFAPAAQLGPFELALQTRKDQTEQALTVVRDTVVRFVAEGPTDAELKAAKDNLVNGFPLRLDSNRKLLDNVANIAW
YNLPLDYLDTWTQRVAAVTREQVRVAFQRVLQPQTMATIVVGGPAPH

Sequences:

>Translated_447_residues
MRAMSLTLKTFLAGMLAAAAHGALAALPIEHWTAATGARVFFVPSPSIPMLDINLDVDAGTRYEPAAKVGLASLTAGMLD
KGVAAVGSTPARDEAAIADAFADVGASFSGGAGGDRTSLRLRTLSDPAERKPAVDLMAQIVAAPTVPDAVLTRDKQRTVA
AIRESLTKPQVLADRAFGTAIYGTHPYGQSATPDTVQSITRDDILRFYHANYTAKRAVVTLIGAISRQEAEAIAEQVTRG
LPPDGATPPALPAVDAPLAKADTVRIAHPAQQATIVMGQPGIARSDKDYFPLLVGNYVLGGGGFSSRLTNEVREKRGLTY
SIGSYFAPAAQLGPFELALQTRKDQTEQALTVVRDTVVRFVAEGPTDAELKAAKDNLVNGFPLRLDSNRKLLDNVANIAW
YNLPLDYLDTWTQRVAAVTREQVRVAFQRVLQPQTMATIVVGGPAPH
>Mature_447_residues
MRAMSLTLKTFLAGMLAAAAHGALAALPIEHWTAATGARVFFVPSPSIPMLDINLDVDAGTRYEPAAKVGLASLTAGMLD
KGVAAVGSTPARDEAAIADAFADVGASFSGGAGGDRTSLRLRTLSDPAERKPAVDLMAQIVAAPTVPDAVLTRDKQRTVA
AIRESLTKPQVLADRAFGTAIYGTHPYGQSATPDTVQSITRDDILRFYHANYTAKRAVVTLIGAISRQEAEAIAEQVTRG
LPPDGATPPALPAVDAPLAKADTVRIAHPAQQATIVMGQPGIARSDKDYFPLLVGNYVLGGGGFSSRLTNEVREKRGLTY
SIGSYFAPAAQLGPFELALQTRKDQTEQALTVVRDTVVRFVAEGPTDAELKAAKDNLVNGFPLRLDSNRKLLDNVANIAW
YNLPLDYLDTWTQRVAAVTREQVRVAFQRVLQPQTMATIVVGGPAPH

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=409, Percent_Identity=22.9828850855746, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357875, Length=407, Percent_Identity=24.3243243243243, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646943, Length=407, Percent_Identity=24.3243243243243, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR007863 [H]

Pfam domain/function: PF05193 Peptidase_M16_C [H]

EC number: NA

Molecular weight: Translated: 47457; Mature: 47457

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAMSLTLKTFLAGMLAAAAHGALAALPIEHWTAATGARVFFVPSPSIPMLDINLDVDAG
CCCHHHHHHHHHHHHHHHHHCCCCEEECHHHHHCCCCCEEEEECCCCCCEEEEEEECCCC
TRYEPAAKVGLASLTAGMLDKGVAAVGSTPARDEAAIADAFADVGASFSGGAGGDRTSLR
CCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEE
LRTLSDPAERKPAVDLMAQIVAAPTVPDAVLTRDKQRTVAAIRESLTKPQVLADRAFGTA
EEECCCCHHCCHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCE
IYGTHPYGQSATPDTVQSITRDDILRFYHANYTAKRAVVTLIGAISRQEAEAIAEQVTRG
EECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPPDGATPPALPAVDAPLAKADTVRIAHPAQQATIVMGQPGIARSDKDYFPLLVGNYVLG
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCEEECCEEEC
GGGFSSRLTNEVREKRGLTYSIGSYFAPAAQLGPFELALQTRKDQTEQALTVVRDTVVRF
CCCHHHHHHHHHHHHCCCEEECCCHHCCHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
VAEGPTDAELKAAKDNLVNGFPLRLDSNRKLLDNVANIAWYNLPLDYLDTWTQRVAAVTR
HHCCCCCCHHHHHHHCCCCCCCEEECCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHH
EQVRVAFQRVLQPQTMATIVVGGPAPH
HHHHHHHHHHHCCCCEEEEEECCCCCC
>Mature Secondary Structure
MRAMSLTLKTFLAGMLAAAAHGALAALPIEHWTAATGARVFFVPSPSIPMLDINLDVDAG
CCCHHHHHHHHHHHHHHHHHCCCCEEECHHHHHCCCCCEEEEECCCCCCEEEEEEECCCC
TRYEPAAKVGLASLTAGMLDKGVAAVGSTPARDEAAIADAFADVGASFSGGAGGDRTSLR
CCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEE
LRTLSDPAERKPAVDLMAQIVAAPTVPDAVLTRDKQRTVAAIRESLTKPQVLADRAFGTA
EEECCCCHHCCHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCE
IYGTHPYGQSATPDTVQSITRDDILRFYHANYTAKRAVVTLIGAISRQEAEAIAEQVTRG
EECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPPDGATPPALPAVDAPLAKADTVRIAHPAQQATIVMGQPGIARSDKDYFPLLVGNYVLG
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCEEECCEEEC
GGGFSSRLTNEVREKRGLTYSIGSYFAPAAQLGPFELALQTRKDQTEQALTVVRDTVVRF
CCCHHHHHHHHHHHHCCCEEECCCHHCCHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
VAEGPTDAELKAAKDNLVNGFPLRLDSNRKLLDNVANIAWYNLPLDYLDTWTQRVAAVTR
HHCCCCCCHHHHHHHCCCCCCCEEECCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHH
EQVRVAFQRVLQPQTMATIVVGGPAPH
HHHHHHHHHHHCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]