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The map label for this gene is manX [C]

Identifier: 17545065

GI number: 17545065

Start: 378996

End: 379505

Strand: Direct

Name: manX [C]

Synonym: RSc0346

Alternate gene names: 17545065

Gene position: 378996-379505 (Clockwise)

Preceding gene: 17545064

Following gene: 17545066

Centisome position: 10.2

GC content: 65.49

Gene sequence:

>510_bases
ATGGCCATAAACGGCCCTGATACAATCGGTCTCACACCGATTCGCTTTTCGATCATGGCAGGGATTCTGATCATCGCCCA
TGCGCCGCTGGCCAGCGCATTGCGCGATTGCGCCGCGCACGTGTATTGCGGCCAGCCGGAGCGGCTGGCGGCGATCGACG
TCCTGCCCGATGCGGAGCCGGCCGGCGTGCTCGCCCAGGCGCGCGCCAAACTCGACGAACTGATCGAGGACAACGGCGCG
CTGGTGCTCACCGACATCTTCGGCGCGACGCCCGCCAACATCGCCTCGCGCCTGGCCGACCCGGGACGGGTGCGCGTGCT
GGCCGGCGTCAATCTGCCGATGCTGGTGCGTGCCATCTGCTATCGCGCCGAGAAGCTGGATCAGCTTGCCGCCAAGGCCC
TGGCCGGCGGCTCGCAAGGCGTGCTGCAGGTCGGCTCGACCGCCGTTCAGAACCAGGTTGCCAACCATCCGGACAAATAT
GCTGCAGAGGGATATCACCATCATCAATAA

Upstream 100 bases:

>100_bases
CGGCCGGCAAGGCGAGCGGCGGACTGGGGCGCAAGCTGGCCTAGCGGACCCCGCACGCGGTCATCCCCCACCGGAGGGAG
GCGGGCCGCATCAGCGCACA

Downstream 100 bases:

>100_bases
GCTCGGGCTGCATGCCCGCGCCTCCGCCAAACTCACGCAGCTCGCCAGCAAGTTCGACAGCCAGATCAAGATGTCGCGCA
ACGGCCGCCAGGTCGATGCC

Product: hypothetical protein

Products: protein histidine; sugar phosphate

Alternate protein names: IIA Component Of Sugar Transport PTS System; PTS System Fructose Subfamily Transporter Subunit IIA; PTS System Fructose-Specific IIA Component; Protein-N P-Phosphohistidine-Sugar Phosphotransferase; PTS System IIA Component; Sugar Transport PTS System IIA Component; PTS System Fructose IIA Component Family Protein; Pts System IIa Component; PTS System Mannose-Type Transporter Subunit IIA; Pts System Fructose Subfamily IIa Component; PTS System Fructose Subfamily Transprotein Subunit IIA; PTS System Mannose/Fructose-Specific Component IIA; Pentitol Phosphotransferase IIA Component; PTS System Component IIA; Phosphotransferase System IIA Component; Phosphotransferase Mannose/Fructose-Specific Component IIA; PTS System Mannose/Fructose-Specific IIA Component; PTS System Fructose IIA Component; IIa Component Of Sugar Transport PTS System; PTS System IIAB Component; Fructose-Specific IIA Component; PTS System IIA Component Domain Protein; PTS System Transporter Subunit IIA

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MAINGPDTIGLTPIRFSIMAGILIIAHAPLASALRDCAAHVYCGQPERLAAIDVLPDAEPAGVLAQARAKLDELIEDNGA
LVLTDIFGATPANIASRLADPGRVRVLAGVNLPMLVRAICYRAEKLDQLAAKALAGGSQGVLQVGSTAVQNQVANHPDKY
AAEGYHHHQ

Sequences:

>Translated_169_residues
MAINGPDTIGLTPIRFSIMAGILIIAHAPLASALRDCAAHVYCGQPERLAAIDVLPDAEPAGVLAQARAKLDELIEDNGA
LVLTDIFGATPANIASRLADPGRVRVLAGVNLPMLVRAICYRAEKLDQLAAKALAGGSQGVLQVGSTAVQNQVANHPDKY
AAEGYHHHQ
>Mature_168_residues
AINGPDTIGLTPIRFSIMAGILIIAHAPLASALRDCAAHVYCGQPERLAAIDVLPDAEPAGVLAQARAKLDELIEDNGAL
VLTDIFGATPANIASRLADPGRVRVLAGVNLPMLVRAICYRAEKLDQLAAKALAGGSQGVLQVGSTAVQNQVANHPDKYA
AEGYHHHQ

Specific function: This Is A Component Of The Phosphoenolpyruvate-Dependent Sugar Phosphotransferase System (Pts), A Major Carbohydrate Active -Transport System. The IIcd Domains Contain The Sugar Binding Site And The Transmembrane Channel; The IIa Domain Contains The Prim

COG id: COG2893

COG function: function code G; Phosphotransferase system, mannose/fructose-specific component IIA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788120, Length=123, Percent_Identity=34.1463414634146, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.1.69

Molecular weight: Translated: 17657; Mature: 17525

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS51096 PTS_EIIA_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAINGPDTIGLTPIRFSIMAGILIIAHAPLASALRDCAAHVYCGQPERLAAIDVLPDAEP
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
AGVLAQARAKLDELIEDNGALVLTDIFGATPANIASRLADPGRVRVLAGVNLPMLVRAIC
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCEEEEECCCHHHHHHHHH
YRAEKLDQLAAKALAGGSQGVLQVGSTAVQNQVANHPDKYAAEGYHHHQ
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCC
>Mature Secondary Structure 
AINGPDTIGLTPIRFSIMAGILIIAHAPLASALRDCAAHVYCGQPERLAAIDVLPDAEP
CCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
AGVLAQARAKLDELIEDNGALVLTDIFGATPANIASRLADPGRVRVLAGVNLPMLVRAIC
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCEEEEECCCHHHHHHHHH
YRAEKLDQLAAKALAGGSQGVLQVGSTAVQNQVANHPDKYAAEGYHHHQ
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA