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The map label for this gene is dctD2 [H]

Identifier: 17545051

GI number: 17545051

Start: 364559

End: 365875

Strand: Direct

Name: dctD2 [H]

Synonym: RSc0332

Alternate gene names: 17545051

Gene position: 364559-365875 (Clockwise)

Preceding gene: 17545050

Following gene: 17545054

Centisome position: 9.81

GC content: 70.16

Gene sequence:

>1317_bases
ATGTCCGAAGGCTTGAACGTTCTCTTCATCGAAGACGATCCGCCCGTCCGCCAGGCCACCGCGCAGAGCCTGGAGCTTGC
CGGCTTCCAGGTCCAGGCCTACGCCAGCGCCGAGGAGGCGGTCGGCCGGATCGACGCCGATTTCTACGGCGTGGTCGTCA
GCGACCTGCGCCTGCCGGGCGCCAGCGGGCTCGACGTGCTGGCGCATTGCCAGTCGTTCGGCACCGGCATTCCGGTGGTG
CTCGTGACCGGCCACGGCGATATCACGATGGCCGTGCAGGCGATGCGCGACGGCGCGTTCGATTTCATCGAGAAGCCGTT
CCCCGCCGAGCGCCTGACCGAGACCGTGCGCCGCGCCGTCGAGCGCCGCGCGCTGGAGCTGGAAAACCGCGCCCTGCGCC
GCGAGCTGGCGGGGCCGGCGGCGGGCACGCGCATCATCGGCCGCTCCCAGGCGATGGCCTCGGTGCGCGCGCTGATCGAC
AACGTGGCCGCCACCGACGCGCCGGTGCTCATCAACGGCGAGACCGGCACCGGCAAGGAACTGGTCGCGCGCAGCCTGCA
CACGCTGTCGCCGCGCCACGACAAGCCGTTCATCGCGCTGAACTGCGGCGCGGTGCCCGAGCAGATCTTCGAGAGCGAGA
TGTTCGGCCATGAGGCCGGCGCCTTCACCGGCGCGGGCAAGCGGCGCATCGGCAAGATCGAGCACGCATCGGGCGGCACG
CTCTTCCTCGACGAGATCGAGAGCATGCCGCTGGCGCTGCAGGTCAAGCTGCTGCGTGTGCTGCAGGAGGGCATGCTCGA
GCGCCTGGGCTCCAACGCCTCGGTGCGCATCGACGTGCGCATCGTCGCCGCCGCCAAGGGCGACATGGAGGCGCTGATCG
AGGCCGGCGGCTTCCGGCGCGACCTGTACTATCGCCTGAACGTCGTCGCCATCGACCTGCCGCCACTGCGCGAGCGCCGC
GAAGACATCATCCCGCTGTTCGAGCACTTCCTGCTGGAGGCCGCCGTGCGCTATCAGCGTCCGTTGCCGATGCTGTCCGA
GCGCCAGCGGCACGAACTGATGCAATCGAACTGGCCCGGCAACGTGCGCGAGCTGCGCAATGCCGCCGATCGCCTGGTGC
TGGGCGTCGGCCGCACGCCCGTCGTCTCCGATGCGGCGGAAGACGGCATGCCGCTCAAGGAGCGGGTCGAGCGCTACGAG
CGCACGGTGATCGCGGAGACGCTGGCGCGCACCGGTGGCTCCGTCCACCAGGCCGCCGACATCCTGCAGGTCGGGCGCGC
GACGCTGTACGACAAGATCAAGCGCTACGGCCTCTGA

Upstream 100 bases:

>100_bases
AATGTGCCGGGCGGCGGCGCCCAGTTCACGCTGTCGCTGGTCCGCGCCGAGGTGGTGCCGGCCGCGACGCCCTGACCCAT
TCCTTTCACCCAAACGATCC

Downstream 100 bases:

>100_bases
CCGGCCGTTGCCGATCCGAATGAAAAACGCCCGGCATCGACCGGGCGTTTCTGTTTCGGCGGGGGGCTGGCCTGGCTGTC
AGGCCTGCTTGGCGAGCGTG

Product: C4-dicarboxylate transport response regulator transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MSEGLNVLFIEDDPPVRQATAQSLELAGFQVQAYASAEEAVGRIDADFYGVVVSDLRLPGASGLDVLAHCQSFGTGIPVV
LVTGHGDITMAVQAMRDGAFDFIEKPFPAERLTETVRRAVERRALELENRALRRELAGPAAGTRIIGRSQAMASVRALID
NVAATDAPVLINGETGTGKELVARSLHTLSPRHDKPFIALNCGAVPEQIFESEMFGHEAGAFTGAGKRRIGKIEHASGGT
LFLDEIESMPLALQVKLLRVLQEGMLERLGSNASVRIDVRIVAAAKGDMEALIEAGGFRRDLYYRLNVVAIDLPPLRERR
EDIIPLFEHFLLEAAVRYQRPLPMLSERQRHELMQSNWPGNVRELRNAADRLVLGVGRTPVVSDAAEDGMPLKERVERYE
RTVIAETLARTGGSVHQAADILQVGRATLYDKIKRYGL

Sequences:

>Translated_438_residues
MSEGLNVLFIEDDPPVRQATAQSLELAGFQVQAYASAEEAVGRIDADFYGVVVSDLRLPGASGLDVLAHCQSFGTGIPVV
LVTGHGDITMAVQAMRDGAFDFIEKPFPAERLTETVRRAVERRALELENRALRRELAGPAAGTRIIGRSQAMASVRALID
NVAATDAPVLINGETGTGKELVARSLHTLSPRHDKPFIALNCGAVPEQIFESEMFGHEAGAFTGAGKRRIGKIEHASGGT
LFLDEIESMPLALQVKLLRVLQEGMLERLGSNASVRIDVRIVAAAKGDMEALIEAGGFRRDLYYRLNVVAIDLPPLRERR
EDIIPLFEHFLLEAAVRYQRPLPMLSERQRHELMQSNWPGNVRELRNAADRLVLGVGRTPVVSDAAEDGMPLKERVERYE
RTVIAETLARTGGSVHQAADILQVGRATLYDKIKRYGL
>Mature_437_residues
SEGLNVLFIEDDPPVRQATAQSLELAGFQVQAYASAEEAVGRIDADFYGVVVSDLRLPGASGLDVLAHCQSFGTGIPVVL
VTGHGDITMAVQAMRDGAFDFIEKPFPAERLTETVRRAVERRALELENRALRRELAGPAAGTRIIGRSQAMASVRALIDN
VAATDAPVLINGETGTGKELVARSLHTLSPRHDKPFIALNCGAVPEQIFESEMFGHEAGAFTGAGKRRIGKIEHASGGTL
FLDEIESMPLALQVKLLRVLQEGMLERLGSNASVRIDVRIVAAAKGDMEALIEAGGFRRDLYYRLNVVAIDLPPLRERRE
DIIPLFEHFLLEAAVRYQRPLPMLSERQRHELMQSNWPGNVRELRNAADRLVLGVGRTPVVSDAAEDGMPLKERVERYER
TVIAETLARTGGSVHQAADILQVGRATLYDKIKRYGL

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=451, Percent_Identity=39.0243902439024, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1790299, Length=473, Percent_Identity=38.4778012684989, Blast_Score=301, Evalue=5e-83,
Organism=Escherichia coli, GI1790437, Length=448, Percent_Identity=37.9464285714286, Blast_Score=298, Evalue=6e-82,
Organism=Escherichia coli, GI1788905, Length=442, Percent_Identity=39.5927601809955, Blast_Score=292, Evalue=2e-80,
Organism=Escherichia coli, GI87082117, Length=341, Percent_Identity=41.6422287390029, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789087, Length=335, Percent_Identity=43.5820895522388, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1789233, Length=320, Percent_Identity=41.25, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI87082152, Length=318, Percent_Identity=42.1383647798742, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI87081872, Length=255, Percent_Identity=45.4901960784314, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1786524, Length=310, Percent_Identity=40.6451612903226, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI1787583, Length=314, Percent_Identity=38.5350318471338, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI87081858, Length=290, Percent_Identity=31.7241379310345, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1789828, Length=239, Percent_Identity=35.1464435146443, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789809, Length=127, Percent_Identity=31.496062992126, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=32.7731092436975, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 47971; Mature: 47839

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEGLNVLFIEDDPPVRQATAQSLELAGFQVQAYASAEEAVGRIDADFYGVVVSDLRLPG
CCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCHHHHHHHHHHCCCC
ASGLDVLAHCQSFGTGIPVVLVTGHGDITMAVQAMRDGAFDFIEKPFPAERLTETVRRAV
CCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHH
ERRALELENRALRRELAGPAAGTRIIGRSQAMASVRALIDNVAATDAPVLINGETGTGKE
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHH
LVARSLHTLSPRHDKPFIALNCGAVPEQIFESEMFGHEAGAFTGAGKRRIGKIEHASGGT
HHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHCCCCEECCCCE
LFLDEIESMPLALQVKLLRVLQEGMLERLGSNASVRIDVRIVAAAKGDMEALIEAGGFRR
EEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHCCCCCE
DLYYRLNVVAIDLPPLRERREDIIPLFEHFLLEAAVRYQRPLPMLSERQRHELMQSNWPG
EEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
NVRELRNAADRLVLGVGRTPVVSDAAEDGMPLKERVERYERTVIAETLARTGGSVHQAAD
CHHHHHHHHHHEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ILQVGRATLYDKIKRYGL
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEGLNVLFIEDDPPVRQATAQSLELAGFQVQAYASAEEAVGRIDADFYGVVVSDLRLPG
CCCCEEEEECCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCHHHHHHHHHHCCCC
ASGLDVLAHCQSFGTGIPVVLVTGHGDITMAVQAMRDGAFDFIEKPFPAERLTETVRRAV
CCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHH
ERRALELENRALRRELAGPAAGTRIIGRSQAMASVRALIDNVAATDAPVLINGETGTGKE
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHH
LVARSLHTLSPRHDKPFIALNCGAVPEQIFESEMFGHEAGAFTGAGKRRIGKIEHASGGT
HHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHCCCCEECCCCE
LFLDEIESMPLALQVKLLRVLQEGMLERLGSNASVRIDVRIVAAAKGDMEALIEAGGFRR
EEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHCCCCCE
DLYYRLNVVAIDLPPLRERREDIIPLFEHFLLEAAVRYQRPLPMLSERQRHELMQSNWPG
EEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
NVRELRNAADRLVLGVGRTPVVSDAAEDGMPLKERVERYERTVIAETLARTGGSVHQAAD
CHHHHHHHHHHEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ILQVGRATLYDKIKRYGL
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]