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The map label for this gene is nreC [H]

Identifier: 17544911

GI number: 17544911

Start: 213632

End: 214279

Strand: Direct

Name: nreC [H]

Synonym: RSc0192

Alternate gene names: 17544911

Gene position: 213632-214279 (Clockwise)

Preceding gene: 17544910

Following gene: 17544913

Centisome position: 5.75

GC content: 61.27

Gene sequence:

>648_bases
ATGATCCGCGTGATGATTGCCGACGATCACGCCGTGATGCGCGATGGCGTGCGCCATATTCTGGAGCGCGCCGGAGATTT
CGAGGTTGCGTGCGAAGCCTCTGACGGCACTCAGGTATTGCAACTGGTGCGTGACCACCAGCCACAGGTGATCGTGCTTG
ACCTGTCAATGCCGGGGCGCAGCGGGCTGGAGCTGTTGCGTCAGTTACATGACGATCATCCGACGGTGCGCGTGTTGGTG
CTGACGATGCACGCAGAGGAGCAGTATGTGGCGCGCGCCTTCCGCGCAGGGGCGGCAGCCTACCTGACCAAGGAAAGTGC
CGCGACTGAATTGGTAACGGCGCTGCAGAAGGTGGCACGCGGTGGTACCTATGTCAGTCCACCCATGGCCGAGAAGCTTG
CGCACAGCCTGGGCGAGACCAGCGATGAGGCCGCGCACATGCGCCTGTCTGATCGCGAGATGGAGGTCTATCGCCGGCTA
GTGCTGGGTGAACCGCTCACGGAGATTGCCGCCAGCCTGTGTGTGAGCGCCAAGACCATTAGCACCTACAAGATGCGGTT
GATGGACAAGCTGCAGTTGTCTAGTGAGGCCGCACTCGTGCGCTACGCCATTCGTCATCGCTTGTTCTCTGACGACGACA
CCCTGTAG

Upstream 100 bases:

>100_bases
TGCTAGGCGGCCAGGCCACGATCGCACACACGCCTGACAGCGGCTTTCGCTTGAGCGTACGTTTTCCCGCTACTCAAGAA
GTGACTGAGGAGACCTGATC

Downstream 100 bases:

>100_bases
TCGATCGGCCCCAAGACTCGGCCTGCCATGTTGAGGCGACTACACGTTGCGATCTGTGCTATCCATTGCGCTACTAGGCC
GCCTCTACAGGCGTGAGGCT

Product: response regulator transcription regulator protein

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MIRVMIADDHAVMRDGVRHILERAGDFEVACEASDGTQVLQLVRDHQPQVIVLDLSMPGRSGLELLRQLHDDHPTVRVLV
LTMHAEEQYVARAFRAGAAAYLTKESAATELVTALQKVARGGTYVSPPMAEKLAHSLGETSDEAAHMRLSDREMEVYRRL
VLGEPLTEIAASLCVSAKTISTYKMRLMDKLQLSSEAALVRYAIRHRLFSDDDTL

Sequences:

>Translated_215_residues
MIRVMIADDHAVMRDGVRHILERAGDFEVACEASDGTQVLQLVRDHQPQVIVLDLSMPGRSGLELLRQLHDDHPTVRVLV
LTMHAEEQYVARAFRAGAAAYLTKESAATELVTALQKVARGGTYVSPPMAEKLAHSLGETSDEAAHMRLSDREMEVYRRL
VLGEPLTEIAASLCVSAKTISTYKMRLMDKLQLSSEAALVRYAIRHRLFSDDDTL
>Mature_215_residues
MIRVMIADDHAVMRDGVRHILERAGDFEVACEASDGTQVLQLVRDHQPQVIVLDLSMPGRSGLELLRQLHDDHPTVRVLV
LTMHAEEQYVARAFRAGAAAYLTKESAATELVTALQKVARGGTYVSPPMAEKLAHSLGETSDEAAHMRLSDREMEVYRRL
VLGEPLTEIAASLCVSAKTISTYKMRLMDKLQLSSEAALVRYAIRHRLFSDDDTL

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=211, Percent_Identity=35.0710900473934, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=35.8208955223881, Blast_Score=113, Evalue=8e-27,
Organism=Escherichia coli, GI1788712, Length=207, Percent_Identity=27.536231884058, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788521, Length=206, Percent_Identity=33.0097087378641, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786747, Length=205, Percent_Identity=28.2926829268293, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788546, Length=206, Percent_Identity=31.5533980582524, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787473, Length=182, Percent_Identity=31.8681318681319, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786599, Length=153, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI87082052, Length=104, Percent_Identity=33.6538461538462, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23910; Mature: 23910

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVMIADDHAVMRDGVRHILERAGDFEVACEASDGTQVLQLVRDHQPQVIVLDLSMPGR
CEEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCEEEEEECCCCH
SGLELLRQLHDDHPTVRVLVLTMHAEEQYVARAFRAGAAAYLTKESAATELVTALQKVAR
HHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
GGTYVSPPMAEKLAHSLGETSDEAAHMRLSDREMEVYRRLVLGEPLTEIAASLCVSAKTI
CCCCCCCHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
STYKMRLMDKLQLSSEAALVRYAIRHRLFSDDDTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIRVMIADDHAVMRDGVRHILERAGDFEVACEASDGTQVLQLVRDHQPQVIVLDLSMPGR
CEEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCEEEEEECCCCH
SGLELLRQLHDDHPTVRVLVLTMHAEEQYVARAFRAGAAAYLTKESAATELVTALQKVAR
HHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
GGTYVSPPMAEKLAHSLGETSDEAAHMRLSDREMEVYRRLVLGEPLTEIAASLCVSAKTI
CCCCCCCHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
STYKMRLMDKLQLSSEAALVRYAIRHRLFSDDDTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]