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The map label for this gene is dprE1 [H]

Identifier: 17544891

GI number: 17544891

Start: 193131

End: 194447

Strand: Reverse

Name: dprE1 [H]

Synonym: RSc0172

Alternate gene names: 17544891

Gene position: 194447-193131 (Counterclockwise)

Preceding gene: 17544892

Following gene: 17544890

Centisome position: 5.23

GC content: 68.11

Gene sequence:

>1317_bases
ATGGGAACCGTTCAGTCGTGGGGGCGCTACCCATACGAACCGCAGCAAGCGCACGCGGTCGCGTGGCGCGATGCCCTGGA
TACGACCTGGCTTGCGGCGACGCGCGAACATGGCACAACGCTCGCGTTCGGCAACGGACGCAGCTACGGCGATAGCTGCC
TGGCGGCATCCGGCCATGTCGTGCAAACGCGGCCGCTCGACCGCCTGATCGCCGCGGACTGGAGCACAGGCATCCTGCGC
GCAGAGCCCGGCGTGACGCTCGAACAGCTGCTGGAGGTCGCGATCCCGCGCGGCTGGATGCTGCCGGTGACGCCGGGCAC
CAAATACGCGACGCTCGGCGGCGCCATCGCCAATGACGTCCACGGCAAGAACCACCATGTCCGCGGCACGTTCGGACGGC
ATGTGCGCCGCTTCGGCCTGGCCCGCAGCGACGGCACGCACCTCGAGTGCGCGCGCGACAGCCACGCCGAACTGTTCGCG
GCGACGATCGGCGGACTCGGGCTAACCGGCCTCATCCTGTGGGCCGAGATCCAGCTGATGCCGATCCGCTCGAGCCTGGT
CGACGTGACCAGCATTCGCTTCGACAACCTCGACGCGTTCTTCGCGCTGTCCGAGCGCCTCGATCCGCTGCACGAATACA
GCGTGGCCTGGGTGGACTGCCGGAGCCGGGGCAACGCGCTCGGGCGCGGTGTTTTCATGGTGGGCGACCATGCCACCGAC
GGCCCGCTCGCCGTCGATCGCCGCCCCAAGCGCACCGTGCCGTTCACCTTGCCCGTCCCGCTGTTCAACCGCGTCACGCT
GCAGGGCTTCAACGCGCTCTATTTTCGGGGCCGGCGCAGCGGTGAAGTCCGCTCGCGGGTGAGCTACGACCGCTATTTCT
ATCCGCTCGACAGCCTGCTCGAGTGGAACCGCATCTATGGCCGCGCAGGCTTCCAGCAACACCAGTCCGTGGTCCCTCCG
CACGCGGCGCGGGACGCGGTACGCGCGATTCTCGACGCCATCGCGGCCAGCGGCACCGGCTCGTTCCTGGCCGTGCTCAA
GCGCTGCGGCAATGCGGCGTCGCCCGGCCTGCTGTCCTTTCCGATGGAAGGGACGTCGCTTGCCCTCGACTTTCCGCAGC
GCGAGGCATTGAACACGCGCCTGTTCGCACGGATCGACGCGATCGTGCGGGAAGCGGGCGGGCGCATGTATCCGGCCAAG
GATGCACACATGTCCGGCGCGGACTTCCGTGCAGCCTATCCGCAATGGCAACAGCTCGAAGCGCTCCGGGACCCCGCCAT
GCTGTCACGCTTCTGGGAACGAACCACTCGAACATGA

Upstream 100 bases:

>100_bases
CCAGATGCACGACGACCCCATCGTGTTCGCCGTACGCGACCGGGTGAGCCTCGCCGTCGTGGCACTGTGCGGCTTTATCT
TCTGGGCGGCGATCTGAACA

Downstream 100 bases:

>100_bases
AGAACATCCTGATCGTTGGAGCCACCTCCGCCATCGCGATCGCCTGTGCGCGGCAATGGGCCGCCGAGGGCGCCCGCTTC
TTTCTGGTGGCACGCAACGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MGTVQSWGRYPYEPQQAHAVAWRDALDTTWLAATREHGTTLAFGNGRSYGDSCLAASGHVVQTRPLDRLIAADWSTGILR
AEPGVTLEQLLEVAIPRGWMLPVTPGTKYATLGGAIANDVHGKNHHVRGTFGRHVRRFGLARSDGTHLECARDSHAELFA
ATIGGLGLTGLILWAEIQLMPIRSSLVDVTSIRFDNLDAFFALSERLDPLHEYSVAWVDCRSRGNALGRGVFMVGDHATD
GPLAVDRRPKRTVPFTLPVPLFNRVTLQGFNALYFRGRRSGEVRSRVSYDRYFYPLDSLLEWNRIYGRAGFQQHQSVVPP
HAARDAVRAILDAIAASGTGSFLAVLKRCGNAASPGLLSFPMEGTSLALDFPQREALNTRLFARIDAIVREAGGRMYPAK
DAHMSGADFRAAYPQWQQLEALRDPAMLSRFWERTTRT

Sequences:

>Translated_438_residues
MGTVQSWGRYPYEPQQAHAVAWRDALDTTWLAATREHGTTLAFGNGRSYGDSCLAASGHVVQTRPLDRLIAADWSTGILR
AEPGVTLEQLLEVAIPRGWMLPVTPGTKYATLGGAIANDVHGKNHHVRGTFGRHVRRFGLARSDGTHLECARDSHAELFA
ATIGGLGLTGLILWAEIQLMPIRSSLVDVTSIRFDNLDAFFALSERLDPLHEYSVAWVDCRSRGNALGRGVFMVGDHATD
GPLAVDRRPKRTVPFTLPVPLFNRVTLQGFNALYFRGRRSGEVRSRVSYDRYFYPLDSLLEWNRIYGRAGFQQHQSVVPP
HAARDAVRAILDAIAASGTGSFLAVLKRCGNAASPGLLSFPMEGTSLALDFPQREALNTRLFARIDAIVREAGGRMYPAK
DAHMSGADFRAAYPQWQQLEALRDPAMLSRFWERTTRT
>Mature_437_residues
GTVQSWGRYPYEPQQAHAVAWRDALDTTWLAATREHGTTLAFGNGRSYGDSCLAASGHVVQTRPLDRLIAADWSTGILRA
EPGVTLEQLLEVAIPRGWMLPVTPGTKYATLGGAIANDVHGKNHHVRGTFGRHVRRFGLARSDGTHLECARDSHAELFAA
TIGGLGLTGLILWAEIQLMPIRSSLVDVTSIRFDNLDAFFALSERLDPLHEYSVAWVDCRSRGNALGRGVFMVGDHATDG
PLAVDRRPKRTVPFTLPVPLFNRVTLQGFNALYFRGRRSGEVRSRVSYDRYFYPLDSLLEWNRIYGRAGFQQHQSVVPPH
AARDAVRAILDAIAASGTGSFLAVLKRCGNAASPGLLSFPMEGTSLALDFPQREALNTRLFARIDAIVREAGGRMYPAKD
AHMSGADFRAAYPQWQQLEALRDPAMLSRFWERTTRT

Specific function: Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007173
- InterPro:   IPR016166
- InterPro:   IPR016168
- InterPro:   IPR006094 [H]

Pfam domain/function: PF04030 ALO; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 48426; Mature: 48294

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTVQSWGRYPYEPQQAHAVAWRDALDTTWLAATREHGTTLAFGNGRSYGDSCLAASGHV
CCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHEECCCCCEEEECCCCCCCCCHHHCCCCE
VQTRPLDRLIAADWSTGILRAEPGVTLEQLLEVAIPRGWMLPVTPGTKYATLGGAIANDV
EECCCHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCEEECCCCCCEEECCCHHHHCC
HGKNHHVRGTFGRHVRRFGLARSDGTHLECARDSHAELFAATIGGLGLTGLILWAEIQLM
CCCCCEECCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHEEEEE
PIRSSLVDVTSIRFDNLDAFFALSERLDPLHEYSVAWVDCRSRGNALGRGVFMVGDHATD
ECHHHHHHHHHEEECCCHHHHHHHHHCCHHHHHCEEEEEECCCCCCCCCCEEEECCCCCC
GPLAVDRRPKRTVPFTLPVPLFNRVTLQGFNALYFRGRRSGEVRSRVSYDRYFYPLDSLL
CCEEECCCCCCCCCEEECCCCHHHEECCCCCEEEEECCCCCHHHHHHCHHHEECCHHHHH
EWNRIYGRAGFQQHQSVVPPHAARDAVRAILDAIAASGTGSFLAVLKRCGNAASPGLLSF
HHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEC
PMEGTSLALDFPQREALNTRLFARIDAIVREAGGRMYPAKDAHMSGADFRAAYPQWQQLE
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
ALRDPAMLSRFWERTTRT
HHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GTVQSWGRYPYEPQQAHAVAWRDALDTTWLAATREHGTTLAFGNGRSYGDSCLAASGHV
CCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHEECCCCCEEEECCCCCCCCCHHHCCCCE
VQTRPLDRLIAADWSTGILRAEPGVTLEQLLEVAIPRGWMLPVTPGTKYATLGGAIANDV
EECCCHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCEEECCCCCCEEECCCHHHHCC
HGKNHHVRGTFGRHVRRFGLARSDGTHLECARDSHAELFAATIGGLGLTGLILWAEIQLM
CCCCCEECCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHEEEEE
PIRSSLVDVTSIRFDNLDAFFALSERLDPLHEYSVAWVDCRSRGNALGRGVFMVGDHATD
ECHHHHHHHHHEEECCCHHHHHHHHHCCHHHHHCEEEEEECCCCCCCCCCEEEECCCCCC
GPLAVDRRPKRTVPFTLPVPLFNRVTLQGFNALYFRGRRSGEVRSRVSYDRYFYPLDSLL
CCEEECCCCCCCCCEEECCCCHHHEECCCCCEEEEECCCCCHHHHHHCHHHEECCHHHHH
EWNRIYGRAGFQQHQSVVPPHAARDAVRAILDAIAASGTGSFLAVLKRCGNAASPGLLSF
HHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEC
PMEGTSLALDFPQREALNTRLFARIDAIVREAGGRMYPAKDAHMSGADFRAAYPQWQQLE
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
ALRDPAMLSRFWERTTRT
HHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]