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The map label for this gene is rocF [H]

Identifier: 17544877

GI number: 17544877

Start: 177682

End: 178611

Strand: Reverse

Name: rocF [H]

Synonym: RSc0158

Alternate gene names: 17544877

Gene position: 178611-177682 (Counterclockwise)

Preceding gene: 17544878

Following gene: 17544874

Centisome position: 4.81

GC content: 74.3

Gene sequence:

>930_bases
ATGACCATCATCGACCTGATCGGCGCGGCCATCGGCTGCGGAGCGCGGGACGACGGCTGCAAGGACGGCCCGCGCGCGCT
GCTCCAGGCCGGCGCGCAGCAACGGCTGCAGACGCCCGACACGCACGGCGGCCTGGTGCACGGCATCGAACTGGCGACGC
CGGCCGGCCACAGCCGCGCGGCCCGGCTGGCGGCGCTGCCCGGCGTGGCCGGTTTCTCGCGCGCGCTGGCCGACGCGACG
GCGCACAGCGTGCACGAAAGGCGCGTGCCGGTAGTCATCGGTGGCGACCACTCGTGCGCGATCGGCACGTGGTCGGGCGT
GGCCTCGGCGCTGCGGCCGGCCGGGCCGCTCGGACTGATCTGGATCGACGCCCACCTGGACAGCCACACCCCGCAGAGCA
GCGATTCCGGCGCCATCCACGGCATGCCGCTGGCCGCGCTGCTCGGCCACGGCGCGCGCGAACTGACGCAGGTGCGCGAT
ACGCTTCCCAAGCTGCTGCCGCAGCACGTGGTGGTGATCGGCGCGCGCAGCTACGAGCCGGCCGAACGCGCGCTGATCGA
CCAGTTGGGCGTGCGCGTGATCGACGCCGCGGAAGTCGCCCGCAGCGGTCTGCGCGCGGTGATGGCCGAGGCCATCCGCA
TCGCCGCGGCCGACACCGCGGCCTTCGGGGTGACGGTCGATCTGGATGCCTTCGATCCGGCGGTGGCACCCGGCGTCGGA
TCGCCGGAGCCGGGCGGCCTCACGGGGCAGGACATGACGCAGGCACTGGCCGCCTGCGCCCGCCATGCGCGCTTCGCGGC
GTTCGAGCTGGTGGAATACAACCCGCGCCACGACAAGGGCGGGATCACGGCACGGCTGGCGCTGGACCTGCTGGGCGCCG
TCGCGGGCGCGTTGCACGCCCAGCGCCGCGAATATGCGAGTGCGGCCTGA

Upstream 100 bases:

>100_bases
TGGCGCGGGACGTCATCCGCCGCACGCTGGCCGACTGGCCGCGCCGCAAGGCGGCCTGAGCCGGCGCATCGCACCGCATC
CGGATTCACGGGGAATCGAC

Downstream 100 bases:

>100_bases
GTCGGCCGGCGCTCAGTCCTTGATGCGGAACACTTCCACGCCCACCGACTCGCAATCCGGATAAGCGTCCGGCTTCTCCG
CCGAGACCCGCGCGGCCAGC

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTIIDLIGAAIGCGARDDGCKDGPRALLQAGAQQRLQTPDTHGGLVHGIELATPAGHSRAARLAALPGVAGFSRALADAT
AHSVHERRVPVVIGGDHSCAIGTWSGVASALRPAGPLGLIWIDAHLDSHTPQSSDSGAIHGMPLAALLGHGARELTQVRD
TLPKLLPQHVVVIGARSYEPAERALIDQLGVRVIDAAEVARSGLRAVMAEAIRIAAADTAAFGVTVDLDAFDPAVAPGVG
SPEPGGLTGQDMTQALAACARHARFAAFELVEYNPRHDKGGITARLALDLLGAVAGALHAQRREYASAA

Sequences:

>Translated_309_residues
MTIIDLIGAAIGCGARDDGCKDGPRALLQAGAQQRLQTPDTHGGLVHGIELATPAGHSRAARLAALPGVAGFSRALADAT
AHSVHERRVPVVIGGDHSCAIGTWSGVASALRPAGPLGLIWIDAHLDSHTPQSSDSGAIHGMPLAALLGHGARELTQVRD
TLPKLLPQHVVVIGARSYEPAERALIDQLGVRVIDAAEVARSGLRAVMAEAIRIAAADTAAFGVTVDLDAFDPAVAPGVG
SPEPGGLTGQDMTQALAACARHARFAAFELVEYNPRHDKGGITARLALDLLGAVAGALHAQRREYASAA
>Mature_308_residues
TIIDLIGAAIGCGARDDGCKDGPRALLQAGAQQRLQTPDTHGGLVHGIELATPAGHSRAARLAALPGVAGFSRALADATA
HSVHERRVPVVIGGDHSCAIGTWSGVASALRPAGPLGLIWIDAHLDSHTPQSSDSGAIHGMPLAALLGHGARELTQVRDT
LPKLLPQHVVVIGARSYEPAERALIDQLGVRVIDAAEVARSGLRAVMAEAIRIAAADTAAFGVTVDLDAFDPAVAPGVGS
PEPGGLTGQDMTQALAACARHARFAAFELVEYNPRHDKGGITARLALDLLGAVAGALHAQRREYASAA

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=315, Percent_Identity=29.5238095238095, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI10947139, Length=276, Percent_Identity=29.3478260869565, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI37537722, Length=229, Percent_Identity=28.82096069869, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71996843, Length=305, Percent_Identity=39.0163934426229, Blast_Score=225, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6325146, Length=279, Percent_Identity=27.2401433691756, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24638886, Length=284, Percent_Identity=30.2816901408451, Blast_Score=104, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 31685; Mature: 31554

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIIDLIGAAIGCGARDDGCKDGPRALLQAGAQQRLQTPDTHGGLVHGIELATPAGHSRA
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHH
ARLAALPGVAGFSRALADATAHSVHERRVPVVIGGDHSCAIGTWSGVASALRPAGPLGLI
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEECHHHHHHHHCCCCCEEEE
WIDAHLDSHTPQSSDSGAIHGMPLAALLGHGARELTQVRDTLPKLLPQHVVVIGARSYEP
EEEEECCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCH
AERALIDQLGVRVIDAAEVARSGLRAVMAEAIRIAAADTAAFGVTVDLDAFDPAVAPGVG
HHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCCCCC
SPEPGGLTGQDMTQALAACARHARFAAFELVEYNPRHDKGGITARLALDLLGAVAGALHA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QRREYASAA
HHHHHHCCC
>Mature Secondary Structure 
TIIDLIGAAIGCGARDDGCKDGPRALLQAGAQQRLQTPDTHGGLVHGIELATPAGHSRA
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHH
ARLAALPGVAGFSRALADATAHSVHERRVPVVIGGDHSCAIGTWSGVASALRPAGPLGLI
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEECHHHHHHHHCCCCCEEEE
WIDAHLDSHTPQSSDSGAIHGMPLAALLGHGARELTQVRDTLPKLLPQHVVVIGARSYEP
EEEEECCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCH
AERALIDQLGVRVIDAAEVARSGLRAVMAEAIRIAAADTAAFGVTVDLDAFDPAVAPGVG
HHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCCCCC
SPEPGGLTGQDMTQALAACARHARFAAFELVEYNPRHDKGGITARLALDLLGAVAGALHA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QRREYASAA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]