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The map label for this gene is argC

Identifier: 17544861

GI number: 17544861

Start: 163788

End: 164801

Strand: Direct

Name: argC

Synonym: RSc0142

Alternate gene names: 17544861

Gene position: 163788-164801 (Clockwise)

Preceding gene: 17544860

Following gene: 17544862

Centisome position: 4.41

GC content: 68.64

Gene sequence:

>1014_bases
ATGGCATTCAAGGTTTTCGTCGACGGTCAGGAAGGCACCACCGGCCTTCGTCTGCTCGACTATCTGTCGCAGCGCGACGA
TATCGAGCTCCTGCGCATCGCCGAAGACCGACGCAAGGACCCGGCCGAGCGCGCCAAATTCCTGAACGCCGCCGACGTGG
CCTTCCTGTGCCTGCCGGACGTCGCTTCGCGCGAGGCCGTGTCGCTGGTCGACAACCCCAACACCTGCATCATCGACGCC
AGCACCGCGTTCCGCACCTCGGACGACTGGGCCTACGGCCTGCCCGAGCTGGCGCCCGGCCAGCGCGAGCGCCTGCGCAA
CAGCAAGCGCATCGCCGTGCCCGGCTGCCACGCCAGCGCCTTCGTGCTGCTGATGCGCCCGCTGGTGGAGGCCGGCATCG
TTCCGGCGGATTACCCCATCACCGCGTTCTCGCTGACCGGCTACAGCGGCGGCGGCAAGAAGATGATCGCCGACTACCTC
GCCGCCGATAACCCCAAGCTGCAGAGCCCGCGTCCCTACGCGCTGGCGTTGACGCACAAGCACCTGCCCGAGATGCGCGT
GCAGAGCAAGCTGGCCCTGCCGCCGATCTTCACGCCGGTGGTGGGCAACTTCCTGAAGGGTCTGGCCGTGACGATCGGCC
TGCATCCGCAGCACCTGGCGAGCAAGGTCAGCCCGGCCGATATCGCCAAGGTCTTCGCCGACTACTACCAGGGCGAGCAG
TTCATCCGCGTCGCCCCGGCCGACAACGTCGAGACGCTCGACAACGGCTTCTTCGACGTGCAGGGCGCCAACGACACCAA
CCGCGCCGACCTGTTCGTGTTCGGCTCGGACGAGCGCATGGTCGTCACCGCCCGCCTGGACAACCTGGGCAAGGGCGCGG
CCGGCGCCGCCGTGCAGTGCATGAACGTGCACCTGGGCGTGGACGAGGCGACCAGCCTGCACGTCGAAGCCCCCGTCAAG
GCCGAAGGCCCGGCGCACCCGGTGCGCGAGGCCGCGCCGGATTTCGCGACCTGA

Upstream 100 bases:

>100_bases
GCGATGCGGCAATTTCCACCACAGCCGCTACAATGCAAGGCTCACGCGCCGGCACGGGGCCGGCGCGGCGTTTGGCTCCT
TTGTTATTAGCGAGATCGCC

Downstream 100 bases:

>100_bases
CGCTCGACGCCGCCGCAGCATGTGGAACGCGCCTTCGGGCGCGTTTTTCTTGGGCGGCGCGCGCATCCTGTTATCAGATA
TCCGTATGGCAGAAATATCC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MAFKVFVDGQEGTTGLRLLDYLSQRDDIELLRIAEDRRKDPAERAKFLNAADVAFLCLPDVASREAVSLVDNPNTCIIDA
STAFRTSDDWAYGLPELAPGQRERLRNSKRIAVPGCHASAFVLLMRPLVEAGIVPADYPITAFSLTGYSGGGKKMIADYL
AADNPKLQSPRPYALALTHKHLPEMRVQSKLALPPIFTPVVGNFLKGLAVTIGLHPQHLASKVSPADIAKVFADYYQGEQ
FIRVAPADNVETLDNGFFDVQGANDTNRADLFVFGSDERMVVTARLDNLGKGAAGAAVQCMNVHLGVDEATSLHVEAPVK
AEGPAHPVREAAPDFAT

Sequences:

>Translated_337_residues
MAFKVFVDGQEGTTGLRLLDYLSQRDDIELLRIAEDRRKDPAERAKFLNAADVAFLCLPDVASREAVSLVDNPNTCIIDA
STAFRTSDDWAYGLPELAPGQRERLRNSKRIAVPGCHASAFVLLMRPLVEAGIVPADYPITAFSLTGYSGGGKKMIADYL
AADNPKLQSPRPYALALTHKHLPEMRVQSKLALPPIFTPVVGNFLKGLAVTIGLHPQHLASKVSPADIAKVFADYYQGEQ
FIRVAPADNVETLDNGFFDVQGANDTNRADLFVFGSDERMVVTARLDNLGKGAAGAAVQCMNVHLGVDEATSLHVEAPVK
AEGPAHPVREAAPDFAT
>Mature_336_residues
AFKVFVDGQEGTTGLRLLDYLSQRDDIELLRIAEDRRKDPAERAKFLNAADVAFLCLPDVASREAVSLVDNPNTCIIDAS
TAFRTSDDWAYGLPELAPGQRERLRNSKRIAVPGCHASAFVLLMRPLVEAGIVPADYPITAFSLTGYSGGGKKMIADYLA
ADNPKLQSPRPYALALTHKHLPEMRVQSKLALPPIFTPVVGNFLKGLAVTIGLHPQHLASKVSPADIAKVFADYYQGEQF
IRVAPADNVETLDNGFFDVQGANDTNRADLFVFGSDERMVVTARLDNLGKGAAGAAVQCMNVHLGVDEATSLHVEAPVKA
EGPAHPVREAAPDFAT

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=289, Percent_Identity=30.1038062283737, Blast_Score=88, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6320913, Length=300, Percent_Identity=29.3333333333333, Blast_Score=99, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_RALSO (Q8Y339)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_518263.1
- ProteinModelPortal:   Q8Y339
- GeneID:   1218945
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc0142
- NMPDR:   fig|267608.1.peg.142
- HOGENOM:   HBG294213
- OMA:   IFEYLSA
- ProtClustDB:   PRK11863
- BioCyc:   RSOL267608:RSC0142-MONOMER
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_01110
- InterPro:   IPR010136
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01851

Pfam domain/function: PF01118 Semialdhyde_dh

EC number: =1.2.1.38

Molecular weight: Translated: 36408; Mature: 36277

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFKVFVDGQEGTTGLRLLDYLSQRDDIELLRIAEDRRKDPAERAKFLNAADVAFLCLPD
CEEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCC
VASREAVSLVDNPNTCIIDASTAFRTSDDWAYGLPELAPGQRERLRNSKRIAVPGCHASA
CCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCHHH
FVLLMRPLVEAGIVPADYPITAFSLTGYSGGGKKMIADYLAADNPKLQSPRPYALALTHK
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEHH
HLPEMRVQSKLALPPIFTPVVGNFLKGLAVTIGLHPQHLASKVSPADIAKVFADYYQGEQ
CCCHHHHHHHCCCCCCHHHHHHHHHHHHEEEECCCHHHHHHCCCHHHHHHHHHHHHCCCE
FIRVAPADNVETLDNGFFDVQGANDTNRADLFVFGSDERMVVTARLDNLGKGAAGAAVQC
EEEECCCCCCHHHCCCEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEE
MNVHLGVDEATSLHVEAPVKAEGPAHPVREAAPDFAT
EEEEECCCCCCEEEEECCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure 
AFKVFVDGQEGTTGLRLLDYLSQRDDIELLRIAEDRRKDPAERAKFLNAADVAFLCLPD
EEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCC
VASREAVSLVDNPNTCIIDASTAFRTSDDWAYGLPELAPGQRERLRNSKRIAVPGCHASA
CCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCHHH
FVLLMRPLVEAGIVPADYPITAFSLTGYSGGGKKMIADYLAADNPKLQSPRPYALALTHK
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEHH
HLPEMRVQSKLALPPIFTPVVGNFLKGLAVTIGLHPQHLASKVSPADIAKVFADYYQGEQ
CCCHHHHHHHCCCCCCHHHHHHHHHHHHEEEECCCHHHHHHCCCHHHHHHHHHHHHCCCE
FIRVAPADNVETLDNGFFDVQGANDTNRADLFVFGSDERMVVTARLDNLGKGAAGAAVQC
EEEECCCCCCHHHCCCEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEE
MNVHLGVDEATSLHVEAPVKAEGPAHPVREAAPDFAT
EEEEECCCCCCEEEEECCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852