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The map label for this gene is lpxP [H]

Identifier: 17544854

GI number: 17544854

Start: 157732

End: 158649

Strand: Direct

Name: lpxP [H]

Synonym: RSc0135

Alternate gene names: 17544854

Gene position: 157732-158649 (Clockwise)

Preceding gene: 17544852

Following gene: 17544855

Centisome position: 4.24

GC content: 66.67

Gene sequence:

>918_bases
TTGCCGGACGGCGATTCGAGGCCCTTTTTTCCCCTGTCTCACGCGACCAACACTCCCGCGCATGCACGCATGACCTTCCT
GTTCTGGCTGTTTTCACGCTGGCCCTTGTCGTGGCTGCAGGCGCTGGGCGGCTGGCTGGGAGCCTTGGCGGCACGGGTGC
CGGGCCGCTATCACGACCGGCTCGTCGCCAATTTCCGCCACGCCTATCCCGACGTCACGCCCGCCATGCTCAAGGAAGCG
GGGCGATCCGCCGGCCGCATGGTGTTCGAGATGCCGTACTTCTGGATGCGCAAGAACGGGACGGACATCACGCCGGACCT
GATCGACGACTGCTGGCCGACTTGCGAGCGCCTGCTAGAGAACGGCCGCGGCGTCATTTTCTTGACCCCGCACCTGGGTT
GCTTTGAAGTGCTGCCGCAGGCTTACGCGCGGCGCCTGCCGGTCACGTCGATGTTCAAGCCGCCCCACCAGGAAAGCTTG
CGCGCCTGGATCGAGCGCATGCGCACGCGGCCGAACATGCAGATGGCGCCCGCCGACTCGCGCGGCGTGCGCATGGTGGT
GCGCGCACTCAAACGAGGCGAGGCTGTAGGCATCCTGCCCGACCAGACGCCCACGGCGGGCGAGGGCGTCTGGGCGCCGT
TCTTCGGCAAGCCCGCCTATACGATGACGCTGGTGCACCGCCTGCACCGGCTGACCGGTGCCCCTGTGGCCGTGGTGTTC
AGCGAGCGCCTGCCGCGCGGCAAGGGCTATCGTCTACACCTGCGTGTGATCGGTGATTTACCCGAAGACGCGACTGCCGC
CGCCACCCGCATCAACGCCGAAATCGAACAGTTGATTGCCCTGGCACCGACGCAATATCTCTGGGGCTATAACCGCTACA
AGCGACCGAAGGGCGTGGACGCCCCGCCCGCTGCCTGA

Upstream 100 bases:

>100_bases
TTTATCAACCTCATCCAGGTTTGTGGCCGGACAAGGATTCGCCCCGCAAGTTGTCAGTTAACTCAGCGAATCGCGCTATT
ATACGCGGCACTTCGGGGTC

Downstream 100 bases:

>100_bases
CGCTGCTGCCGCACTTTATGGAACGTTTCACTGCCAAACTCGGACTCGGCTTCCTGTGGCTGCTGTCCTTCTTCCCGTAC
GGTTTCGTCGCCCGCTTCGG

Product: lipid A biosynthesis lauroyl acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MPDGDSRPFFPLSHATNTPAHARMTFLFWLFSRWPLSWLQALGGWLGALAARVPGRYHDRLVANFRHAYPDVTPAMLKEA
GRSAGRMVFEMPYFWMRKNGTDITPDLIDDCWPTCERLLENGRGVIFLTPHLGCFEVLPQAYARRLPVTSMFKPPHQESL
RAWIERMRTRPNMQMAPADSRGVRMVVRALKRGEAVGILPDQTPTAGEGVWAPFFGKPAYTMTLVHRLHRLTGAPVAVVF
SERLPRGKGYRLHLRVIGDLPEDATAAATRINAEIEQLIALAPTQYLWGYNRYKRPKGVDAPPAA

Sequences:

>Translated_305_residues
MPDGDSRPFFPLSHATNTPAHARMTFLFWLFSRWPLSWLQALGGWLGALAARVPGRYHDRLVANFRHAYPDVTPAMLKEA
GRSAGRMVFEMPYFWMRKNGTDITPDLIDDCWPTCERLLENGRGVIFLTPHLGCFEVLPQAYARRLPVTSMFKPPHQESL
RAWIERMRTRPNMQMAPADSRGVRMVVRALKRGEAVGILPDQTPTAGEGVWAPFFGKPAYTMTLVHRLHRLTGAPVAVVF
SERLPRGKGYRLHLRVIGDLPEDATAAATRINAEIEQLIALAPTQYLWGYNRYKRPKGVDAPPAA
>Mature_304_residues
PDGDSRPFFPLSHATNTPAHARMTFLFWLFSRWPLSWLQALGGWLGALAARVPGRYHDRLVANFRHAYPDVTPAMLKEAG
RSAGRMVFEMPYFWMRKNGTDITPDLIDDCWPTCERLLENGRGVIFLTPHLGCFEVLPQAYARRLPVTSMFKPPHQESLR
AWIERMRTRPNMQMAPADSRGVRMVVRALKRGEAVGILPDQTPTAGEGVWAPFFGKPAYTMTLVHRLHRLTGAPVAVVFS
ERLPRGKGYRLHLRVIGDLPEDATAAATRINAEIEQLIALAPTQYLWGYNRYKRPKGVDAPPAA

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=288, Percent_Identity=30.5555555555556, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787292, Length=288, Percent_Identity=27.4305555555556, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 34425; Mature: 34294

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDGDSRPFFPLSHATNTPAHARMTFLFWLFSRWPLSWLQALGGWLGALAARVPGRYHDR
CCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHH
LVANFRHAYPDVTPAMLKEAGRSAGRMVFEMPYFWMRKNGTDITPDLIDDCWPTCERLLE
HHHHHHHHCCCCCHHHHHHHHHHHCCEEEECCHHEEECCCCCCCHHHHHHHHHHHHHHHH
NGRGVIFLTPHLGCFEVLPQAYARRLPVTSMFKPPHQESLRAWIERMRTRPNMQMAPADS
CCCEEEEECCCCCHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHCCCCCEECCCCC
RGVRMVVRALKRGEAVGILPDQTPTAGEGVWAPFFGKPAYTMTLVHRLHRLTGAPVAVVF
HHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHH
SERLPRGKGYRLHLRVIGDLPEDATAAATRINAEIEQLIALAPTQYLWGYNRYKRPKGVD
HHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHCCCCCCCC
APPAA
CCCCC
>Mature Secondary Structure 
PDGDSRPFFPLSHATNTPAHARMTFLFWLFSRWPLSWLQALGGWLGALAARVPGRYHDR
CCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHH
LVANFRHAYPDVTPAMLKEAGRSAGRMVFEMPYFWMRKNGTDITPDLIDDCWPTCERLLE
HHHHHHHHCCCCCHHHHHHHHHHHCCEEEECCHHEEECCCCCCCHHHHHHHHHHHHHHHH
NGRGVIFLTPHLGCFEVLPQAYARRLPVTSMFKPPHQESLRAWIERMRTRPNMQMAPADS
CCCEEEEECCCCCHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHCCCCCEECCCCC
RGVRMVVRALKRGEAVGILPDQTPTAGEGVWAPFFGKPAYTMTLVHRLHRLTGAPVAVVF
HHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHH
SERLPRGKGYRLHLRVIGDLPEDATAAATRINAEIEQLIALAPTQYLWGYNRYKRPKGVD
HHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHCCCCCCCC
APPAA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]