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The map label for this gene is yodT [H]

Identifier: 17544801

GI number: 17544801

Start: 95113

End: 96465

Strand: Direct

Name: yodT [H]

Synonym: RSc0082

Alternate gene names: 17544801

Gene position: 95113-96465 (Clockwise)

Preceding gene: 17544800

Following gene: 17544802

Centisome position: 2.56

GC content: 71.54

Gene sequence:

>1353_bases
ATGACACCCTCCACCACTTCCGTTTTCCATCGCGACCCGCGCAAGACGCTGCCGACCGCCGTCGGCGGCGAAAGCATGAT
GCTGATCGATGCCGAAGGCAAGCGTTACCTCGACGCCAGCGGCGGCGCGGCGGTTTCGTGCCTGGGCCATGGGCATCCGC
GCGTGGTCGAGGCCATCTGCAAGCAGGTGCGCGCGCTGGCCTATGCGCACACGTCGTTCTTCACCACCGCCGTGGCGGAG
GAGTTGGCCGCGCGCCTGGCCGCGGCCGCGCCGGGTGACCTGGGCCATGTCTATTTCGTCTCCGGCGGCTCGGAGGCCAT
CGAGGCGGCGCTGAAGCTGGCGCGGCAGTACTTCGTCGAGATCGGCCAGCCGCAGCGCCAGTACTTCATCGCGCGTCGGC
AGAGCTATCACGGCAACACGCTGGGCGCGCTGGCGATCGGCGGCAACGCGTGGCGGCGCGAGCCGTTCCTGCCGCTGCTG
GTGCCGGCGCACCATGTGTCGCCGTGCTTCGCTTACCGCGAGCGGCGCGACGGCGAGACCGACGCGCAATACGTGCAGCG
CCTGGCCGACGAGCTGGACGCCAAGATCGTCGAGCTGGGGGCGGACCGCGTCGCCGCGTTCATCGCCGAGACGGTGGTGG
GCGCCACGGCCGGCGCGGTGCCGCCGGTGGCTGACTACTTCCGCAAGATCCGAGCGGTGTGCGACCGCCACGGCGTGCTG
CTGATCCTGGACGAGGTGATGTCCGGCATGGGTCGCACCGGCCATCTCTTCGCGTGCGAGGAGGACGGCGTGGTGCCCGA
CCTGATCGCCATCGCCAAGGGGCTGGGCGGCGGCTACCAGCCGATCGGCGCGATGATCGCCAGCGACCGCATCTATGACG
CGATCACGCGCGGCTCGGGCTTCTTCCAGCACGGCCACACCTACATCGGCCATGCCACGGCGTGCGCGGCGGCGCTGGAG
GTGCAGAAGGTGATCGCCGAAGAGAACCTGCTCGCCAATGTGCTGGCGCGCGGCGAGCAGTTGCGCGCTGCGCTGCGCGA
GCGCTTTGCCGCGCATCCGCACGTGGGCGACGTGCGCGGCCGCGGCCTGTTCGTCGGCGTGGAGCTGGTGGCGGACCGGG
GCACCAAGGCGCCCCTGCCGCCCGCGCGCAAGACGCACGCGCGCGTGCGGGCCGAGGCGATGCAGCGCGGCCTGATGGTG
TATCCGATGGGCGGCACCATCGACGGCCAGCGCGGCGACCACATCCTGCTGGCGCCGCCGTTCATCGCCACCGCGCAGGA
CATCGACGCGATCGTCGCGCGCCTGGGCGACGCGGTCGAGGCGGCCACCGCCAACGCGCTGGAGGCGGCATGA

Upstream 100 bases:

>100_bases
GCAACAGCAAGCCTATGTACGCAACGCGCGCCGCAGCGAAGCGGCCATCGCCGTGCCCGCGCAGCCCTGACCCAGCCAAC
CGCCTCCAGCCCCATCGACC

Downstream 100 bases:

>100_bases
CGCTGCCGCTGTCCATCGCCGTCGCGCCCAACGGTGCGCGCAAGACCCACGCCGACCATCCCGCGCTGCCGATCACGCCG
GACGAGCTGGCCGCCTGCGC

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MTPSTTSVFHRDPRKTLPTAVGGESMMLIDAEGKRYLDASGGAAVSCLGHGHPRVVEAICKQVRALAYAHTSFFTTAVAE
ELAARLAAAAPGDLGHVYFVSGGSEAIEAALKLARQYFVEIGQPQRQYFIARRQSYHGNTLGALAIGGNAWRREPFLPLL
VPAHHVSPCFAYRERRDGETDAQYVQRLADELDAKIVELGADRVAAFIAETVVGATAGAVPPVADYFRKIRAVCDRHGVL
LILDEVMSGMGRTGHLFACEEDGVVPDLIAIAKGLGGGYQPIGAMIASDRIYDAITRGSGFFQHGHTYIGHATACAAALE
VQKVIAEENLLANVLARGEQLRAALRERFAAHPHVGDVRGRGLFVGVELVADRGTKAPLPPARKTHARVRAEAMQRGLMV
YPMGGTIDGQRGDHILLAPPFIATAQDIDAIVARLGDAVEAATANALEAA

Sequences:

>Translated_450_residues
MTPSTTSVFHRDPRKTLPTAVGGESMMLIDAEGKRYLDASGGAAVSCLGHGHPRVVEAICKQVRALAYAHTSFFTTAVAE
ELAARLAAAAPGDLGHVYFVSGGSEAIEAALKLARQYFVEIGQPQRQYFIARRQSYHGNTLGALAIGGNAWRREPFLPLL
VPAHHVSPCFAYRERRDGETDAQYVQRLADELDAKIVELGADRVAAFIAETVVGATAGAVPPVADYFRKIRAVCDRHGVL
LILDEVMSGMGRTGHLFACEEDGVVPDLIAIAKGLGGGYQPIGAMIASDRIYDAITRGSGFFQHGHTYIGHATACAAALE
VQKVIAEENLLANVLARGEQLRAALRERFAAHPHVGDVRGRGLFVGVELVADRGTKAPLPPARKTHARVRAEAMQRGLMV
YPMGGTIDGQRGDHILLAPPFIATAQDIDAIVARLGDAVEAATANALEAA
>Mature_449_residues
TPSTTSVFHRDPRKTLPTAVGGESMMLIDAEGKRYLDASGGAAVSCLGHGHPRVVEAICKQVRALAYAHTSFFTTAVAEE
LAARLAAAAPGDLGHVYFVSGGSEAIEAALKLARQYFVEIGQPQRQYFIARRQSYHGNTLGALAIGGNAWRREPFLPLLV
PAHHVSPCFAYRERRDGETDAQYVQRLADELDAKIVELGADRVAAFIAETVVGATAGAVPPVADYFRKIRAVCDRHGVLL
ILDEVMSGMGRTGHLFACEEDGVVPDLIAIAKGLGGGYQPIGAMIASDRIYDAITRGSGFFQHGHTYIGHATACAAALEV
QKVIAEENLLANVLARGEQLRAALRERFAAHPHVGDVRGRGLFVGVELVADRGTKAPLPPARKTHARVRAEAMQRGLMVY
PMGGTIDGQRGDHILLAPPFIATAQDIDAIVARLGDAVEAATANALEAA

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=449, Percent_Identity=30.0668151447661, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI13994255, Length=437, Percent_Identity=30.8924485125858, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI226442705, Length=449, Percent_Identity=29.3986636971047, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI226442709, Length=404, Percent_Identity=30.1980198019802, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI4557809, Length=439, Percent_Identity=28.246013667426, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI24119277, Length=456, Percent_Identity=27.6315789473684, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI284507298, Length=333, Percent_Identity=29.1291291291291, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI188536080, Length=386, Percent_Identity=23.0569948186528, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI38679950, Length=386, Percent_Identity=23.0569948186528, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI38679946, Length=386, Percent_Identity=23.0569948186528, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI145693181, Length=353, Percent_Identity=35.4107648725212, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1789016, Length=407, Percent_Identity=34.6437346437346, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1788044, Length=421, Percent_Identity=32.541567695962, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1789759, Length=428, Percent_Identity=31.7757009345794, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1786991, Length=424, Percent_Identity=30.6603773584906, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1787560, Length=447, Percent_Identity=29.3064876957494, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1786349, Length=320, Percent_Identity=30.3125, Blast_Score=89, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71992977, Length=449, Percent_Identity=30.9576837416481, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI32564660, Length=444, Percent_Identity=30.4054054054054, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI25144271, Length=449, Percent_Identity=26.0579064587973, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI25144274, Length=239, Percent_Identity=30.1255230125523, Blast_Score=111, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6324432, Length=392, Percent_Identity=30.3571428571429, Blast_Score=166, Evalue=9e-42,
Organism=Saccharomyces cerevisiae, GI6323470, Length=421, Percent_Identity=28.978622327791, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6324386, Length=343, Percent_Identity=25.9475218658892, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356575, Length=453, Percent_Identity=31.3465783664459, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI161085790, Length=441, Percent_Identity=29.9319727891156, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28574759, Length=378, Percent_Identity=32.2751322751323, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI21357415, Length=413, Percent_Identity=30.0242130750605, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281366494, Length=377, Percent_Identity=23.6074270557029, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24667139, Length=377, Percent_Identity=23.6074270557029, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24667143, Length=377, Percent_Identity=23.6074270557029, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 47934; Mature: 47803

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSTTSVFHRDPRKTLPTAVGGESMMLIDAEGKRYLDASGGAAVSCLGHGHPRVVEAIC
CCCCCCHHHHCCCHHHCCCCCCCCEEEEEECCCCEEEECCCCCEEEECCCCCHHHHHHHH
KQVRALAYAHTSFFTTAVAEELAARLAAAAPGDLGHVYFVSGGSEAIEAALKLARQYFVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
IGQPQRQYFIARRQSYHGNTLGALAIGGNAWRREPFLPLLVPAHHVSPCFAYRERRDGET
CCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEECCHHHCCHHHHHHHHCCCCH
DAQYVQRLADELDAKIVELGADRVAAFIAETVVGATAGAVPPVADYFRKIRAVCDRHGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEE
LILDEVMSGMGRTGHLFACEEDGVVPDLIAIAKGLGGGYQPIGAMIASDRIYDAITRGSG
EEHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
FFQHGHTYIGHATACAAALEVQKVIAEENLLANVLARGEQLRAALRERFAAHPHVGDVRG
CHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCC
RGLFVGVELVADRGTKAPLPPARKTHARVRAEAMQRGLMVYPMGGTIDGQRGDHILLAPP
CEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCEECCCCCCEEEECCC
FIATAQDIDAIVARLGDAVEAATANALEAA
CHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPSTTSVFHRDPRKTLPTAVGGESMMLIDAEGKRYLDASGGAAVSCLGHGHPRVVEAIC
CCCCCHHHHCCCHHHCCCCCCCCEEEEEECCCCEEEECCCCCEEEECCCCCHHHHHHHH
KQVRALAYAHTSFFTTAVAEELAARLAAAAPGDLGHVYFVSGGSEAIEAALKLARQYFVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
IGQPQRQYFIARRQSYHGNTLGALAIGGNAWRREPFLPLLVPAHHVSPCFAYRERRDGET
CCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEECCHHHCCHHHHHHHHCCCCH
DAQYVQRLADELDAKIVELGADRVAAFIAETVVGATAGAVPPVADYFRKIRAVCDRHGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEE
LILDEVMSGMGRTGHLFACEEDGVVPDLIAIAKGLGGGYQPIGAMIASDRIYDAITRGSG
EEHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
FFQHGHTYIGHATACAAALEVQKVIAEENLLANVLARGEQLRAALRERFAAHPHVGDVRG
CHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCC
RGLFVGVELVADRGTKAPLPPARKTHARVRAEAMQRGLMVYPMGGTIDGQRGDHILLAPP
CEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCEECCCCCCEEEECCC
FIATAQDIDAIVARLGDAVEAATANALEAA
CHHHHHHHHHHHHHHCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]