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The map label for this gene is leuE [H]

Identifier: 17544792

GI number: 17544792

Start: 83613

End: 84260

Strand: Direct

Name: leuE [H]

Synonym: RSc0073

Alternate gene names: 17544792

Gene position: 83613-84260 (Clockwise)

Preceding gene: 17544791

Following gene: 17544793

Centisome position: 2.25

GC content: 69.14

Gene sequence:

>648_bases
ATGAGTACGCTGGGCATCATCAACCTGCCGGTCTTCATGCTTGCCGTGCTCCTGCTCAACGTGACGCCCGGGCCGGATAC
CGCCTATATCGTCGGGCGCAGCGTGTCGCAGGGGCGCGCGGCGGGGCTGATGTCGAGCCTGGGTGTGTCGGCGGGGTGCT
GCGTGCACGTGCTGGCGGTGGCCTTCGGGCTGACGGCGCTGCTGGCCGCGTCGGCCGTGGCGTTCACGGTGATCAAGGCG
ATCGGCGCGGCGTATCTGATCTATCTGGGCGGCCGCATGCTGCTGGCGCCGGCCGGGAGCGACGACGCGCCCGTGGCGCA
AGCGGTCGCTACTGCCCGCCGTCCGCTGCGCGCGCTGTTCATGCAGGGGTTCCTGACCAATGTGCTGAACCCGAAGGTGG
TGCTGTTCTTCCTGTCGTTCTTCCCGCAATTCGTCGATCCGGGCGCGAGCCACAAGGCGGCGGCGTTTCTGGTGCTGGGG
GCGGTGTTCATCGTGATGTCGACGGCATGGAACAGCCTGGTCGCCTGGGTGGCGGCCAGCGTCACGCGCCGGGTGGCGGG
CAAGCCGGGTATCAAGCGCTGGCTCGACCGCGTTGTCGGGACGGCGTTCATCGGGCTGGGGGCGCGGCTGGCGTTCACGA
CCCGATGA

Upstream 100 bases:

>100_bases
CCCGCGCGCGAGTTCCTGCAGGGTTTGCCGATCCGGCCGGGGCAGCGCTTCGCTTCGCGCGCCTGAATTTCCCGCTGTCT
TTCCTGGAAGGATTGCCGCC

Downstream 100 bases:

>100_bases
CGCGCGGTTGCGGCGGCCATGGCCGGATGCGGCGAAATACCGCGCAACCCCTTGAATTTTCAGCGCTTAGCGCGATCTAA
GAGACTCGAACGTACGGACC

Product: transporter transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MSTLGIINLPVFMLAVLLLNVTPGPDTAYIVGRSVSQGRAAGLMSSLGVSAGCCVHVLAVAFGLTALLAASAVAFTVIKA
IGAAYLIYLGGRMLLAPAGSDDAPVAQAVATARRPLRALFMQGFLTNVLNPKVVLFFLSFFPQFVDPGASHKAAAFLVLG
AVFIVMSTAWNSLVAWVAASVTRRVAGKPGIKRWLDRVVGTAFIGLGARLAFTTR

Sequences:

>Translated_215_residues
MSTLGIINLPVFMLAVLLLNVTPGPDTAYIVGRSVSQGRAAGLMSSLGVSAGCCVHVLAVAFGLTALLAASAVAFTVIKA
IGAAYLIYLGGRMLLAPAGSDDAPVAQAVATARRPLRALFMQGFLTNVLNPKVVLFFLSFFPQFVDPGASHKAAAFLVLG
AVFIVMSTAWNSLVAWVAASVTRRVAGKPGIKRWLDRVVGTAFIGLGARLAFTTR
>Mature_214_residues
STLGIINLPVFMLAVLLLNVTPGPDTAYIVGRSVSQGRAAGLMSSLGVSAGCCVHVLAVAFGLTALLAASAVAFTVIKAI
GAAYLIYLGGRMLLAPAGSDDAPVAQAVATARRPLRALFMQGFLTNVLNPKVVLFFLSFFPQFVDPGASHKAAAFLVLGA
VFIVMSTAWNSLVAWVAASVTRRVAGKPGIKRWLDRVVGTAFIGLGARLAFTTR

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=208, Percent_Identity=28.8461538461538, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI48994979, Length=203, Percent_Identity=30.5418719211823, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI48994978, Length=196, Percent_Identity=30.6122448979592, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786522, Length=209, Percent_Identity=27.7511961722488, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22349; Mature: 22218

Theoretical pI: Translated: 11.70; Mature: 11.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLGIINLPVFMLAVLLLNVTPGPDTAYIVGRSVSQGRAAGLMSSLGVSAGCCVHVLAV
CCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHH
AFGLTALLAASAVAFTVIKAIGAAYLIYLGGRMLLAPAGSDDAPVAQAVATARRPLRALF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
MQGFLTNVLNPKVVLFFLSFFPQFVDPGASHKAAAFLVLGAVFIVMSTAWNSLVAWVAAS
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTRRVAGKPGIKRWLDRVVGTAFIGLGARLAFTTR
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure 
STLGIINLPVFMLAVLLLNVTPGPDTAYIVGRSVSQGRAAGLMSSLGVSAGCCVHVLAV
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHH
AFGLTALLAASAVAFTVIKAIGAAYLIYLGGRMLLAPAGSDDAPVAQAVATARRPLRALF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
MQGFLTNVLNPKVVLFFLSFFPQFVDPGASHKAAAFLVLGAVFIVMSTAWNSLVAWVAAS
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTRRVAGKPGIKRWLDRVVGTAFIGLGARLAFTTR
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA