Click here to switch to the map view.

The map label for this gene is pdhS [H]

Identifier: 17232566

GI number: 17232566

Start: 6044626

End: 6046191

Strand: Reverse

Name: pdhS [H]

Synonym: all5074

Alternate gene names: 17232566

Gene position: 6046191-6044626 (Counterclockwise)

Preceding gene: 17232568

Following gene: 17232565

Centisome position: 94.27

GC content: 42.02

Gene sequence:

>1566_bases
GTGGTGGCAATGGTAGAGCCGGAAAACAAATTATTTGCCCTCAAGGACGGTTGGGTTTCTCAGGACACAAGAGAACAACA
ACGCCTCAAAGCATTGTCAGAATTAGGTTTGCGACAACCAGAAACAATACCGGTTTTTGAGGAAGCAACTCAAACTGCGG
CTCATTTTTTGGAAGCACCAATTTCTATTTTGGGTTTTATAGATCAAGAGCGTCATTGGTTCAAATCGGCGGTAGGCTTA
TCTAGGCTGGGACTAATGAATCATTTGGCTCAAAGCCGTCAGTTGTTACGCCAGGAGTCGTTCTGCACACAAGTAGTAGA
TAGTCACCAAATACTTGTTATTAATGATACATTACGAGTAACAGATCCGGCGCTGGCAACTGGTAAGTTGATCCAAGATT
ATGGTATTCGTGCTTATCTGGGCGCTCCCTTAATTGATGCTGCGGGAAATTGCCTTGGTGCATTAGCCGTGATGGATTTA
GTCCCGCGCAATTTTACAACCAGGGATGTCGAATTTCTACAAATTATTGCCCGTTGGAGCATGAGCGAATTCGAGCGCAA
TCGCCTACTGATGCAGGTAAAATCAGATCAGAGTAGCTTCAAGAGTTCGCCCACATTCATACCTCATGACGAGCCTAATG
AGCCTAAGCTGACTCTGCCTCATGTAGAAGTAGAAAAAGACTCACATTCAACCAAGCAAGTCAAAATAGAACTCTTGGCA
CAACTTACCCAAGAATTACGTACACCCTTGACATCCGTATTAGGGATGGCAAGTGTGTTGGGACGTGAGATTTATGGGCC
TCTGACAACAAAGCAACGTGAATATCTGGATATAATCCAACACAGTGGTCGGTATTTACTCTCTTTAGTGAATGAAATTA
CCGAGCTAGGAGCAATAGATGAAAAGGCAAGTGTATTGAATCTAGCTCCTGTAGATATTGAAATGCTGTGTCAACAAGCT
ATTAATACTTTAGAGGAAGCAGCTAATCGTCGTGAACAAGACATTCGATTGTCCATAGAACCGGGACGTAGCCGTATTTG
GCCGTTAGATAAAGACAAAGTTCGGCAAATGCTGTATCACCTAATTTTCAGTGTAATTCAATTTTCTGCTACTGGTAGTA
TTGTGCGTATTCATGTCTCATATAAAGAAAATGCGCTGAACATTACTGTTTGGGTTTCTCACCCTTGGCTAGGCGATGGG
ATTACTGATGTTGACCCATATTTCCGCCTGAATTCATTGTCTGTTATGGATTTGGCTGGTGATGCTGCTATGTACAGTGT
ACCTCCTGAACCTAAGGAAGAAATAAAAAGTTTACCTGTGACACTGGAAAAGTTACGATCCTTAGCTGATTCTTATTCTG
ATCTTTTGGCTGTAAATCCTGATGGCGATTCCAGCAAAAGTAAAGGTAATTTGTCCCGTGAAAGCTTAGGTTTATTGTTG
AGTTGTCAGTTAGCTGAATTACACGGTGGTCAAATTTCTATTCAAGGTTCACGGGAATCAGGACATCGTTATTTAGTGAA
CTTACCATTACAATTGGCAAAAAATCCGGAAGTTAGCGATATTTGA

Upstream 100 bases:

>100_bases
TTGTTTATCAGCAGTCAAATTGGGGAATGCTTAAGGATAGGAAATCATAACCCAGCTTAAGTGGTTATATAAATTACATT
ATCGAAAATTTATTAAGGTA

Downstream 100 bases:

>100_bases
TGAAAATTTCTATTTCCTACTGCATTTTGATGACCGAATGCTTAACGTCAATCAGCATGGATAGGAATTAATAATTTGCA
ATTTGAGTTATTACCTTTTT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MVAMVEPENKLFALKDGWVSQDTREQQRLKALSELGLRQPETIPVFEEATQTAAHFLEAPISILGFIDQERHWFKSAVGL
SRLGLMNHLAQSRQLLRQESFCTQVVDSHQILVINDTLRVTDPALATGKLIQDYGIRAYLGAPLIDAAGNCLGALAVMDL
VPRNFTTRDVEFLQIIARWSMSEFERNRLLMQVKSDQSSFKSSPTFIPHDEPNEPKLTLPHVEVEKDSHSTKQVKIELLA
QLTQELRTPLTSVLGMASVLGREIYGPLTTKQREYLDIIQHSGRYLLSLVNEITELGAIDEKASVLNLAPVDIEMLCQQA
INTLEEAANRREQDIRLSIEPGRSRIWPLDKDKVRQMLYHLIFSVIQFSATGSIVRIHVSYKENALNITVWVSHPWLGDG
ITDVDPYFRLNSLSVMDLAGDAAMYSVPPEPKEEIKSLPVTLEKLRSLADSYSDLLAVNPDGDSSKSKGNLSRESLGLLL
SCQLAELHGGQISIQGSRESGHRYLVNLPLQLAKNPEVSDI

Sequences:

>Translated_521_residues
MVAMVEPENKLFALKDGWVSQDTREQQRLKALSELGLRQPETIPVFEEATQTAAHFLEAPISILGFIDQERHWFKSAVGL
SRLGLMNHLAQSRQLLRQESFCTQVVDSHQILVINDTLRVTDPALATGKLIQDYGIRAYLGAPLIDAAGNCLGALAVMDL
VPRNFTTRDVEFLQIIARWSMSEFERNRLLMQVKSDQSSFKSSPTFIPHDEPNEPKLTLPHVEVEKDSHSTKQVKIELLA
QLTQELRTPLTSVLGMASVLGREIYGPLTTKQREYLDIIQHSGRYLLSLVNEITELGAIDEKASVLNLAPVDIEMLCQQA
INTLEEAANRREQDIRLSIEPGRSRIWPLDKDKVRQMLYHLIFSVIQFSATGSIVRIHVSYKENALNITVWVSHPWLGDG
ITDVDPYFRLNSLSVMDLAGDAAMYSVPPEPKEEIKSLPVTLEKLRSLADSYSDLLAVNPDGDSSKSKGNLSRESLGLLL
SCQLAELHGGQISIQGSRESGHRYLVNLPLQLAKNPEVSDI
>Mature_521_residues
MVAMVEPENKLFALKDGWVSQDTREQQRLKALSELGLRQPETIPVFEEATQTAAHFLEAPISILGFIDQERHWFKSAVGL
SRLGLMNHLAQSRQLLRQESFCTQVVDSHQILVINDTLRVTDPALATGKLIQDYGIRAYLGAPLIDAAGNCLGALAVMDL
VPRNFTTRDVEFLQIIARWSMSEFERNRLLMQVKSDQSSFKSSPTFIPHDEPNEPKLTLPHVEVEKDSHSTKQVKIELLA
QLTQELRTPLTSVLGMASVLGREIYGPLTTKQREYLDIIQHSGRYLLSLVNEITELGAIDEKASVLNLAPVDIEMLCQQA
INTLEEAANRREQDIRLSIEPGRSRIWPLDKDKVRQMLYHLIFSVIQFSATGSIVRIHVSYKENALNITVWVSHPWLGDG
ITDVDPYFRLNSLSVMDLAGDAAMYSVPPEPKEEIKSLPVTLEKLRSLADSYSDLLAVNPDGDSSKSKGNLSRESLGLLL
SCQLAELHGGQISIQGSRESGHRYLVNLPLQLAKNPEVSDI

Specific function: Functions as a polar differentiation marker. Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Note=Localizes at the old pole of dividing cells. Colocalizes with divK (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58273; Mature: 58273

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAMVEPENKLFALKDGWVSQDTREQQRLKALSELGLRQPETIPVFEEATQTAAHFLEAP
CEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
ISILGFIDQERHWFKSAVGLSRLGLMNHLAQSRQLLRQESFCTQVVDSHQILVINDTLRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEE
TDPALATGKLIQDYGIRAYLGAPLIDAAGNCLGALAVMDLVPRNFTTRDVEFLQIIARWS
CCCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
MSEFERNRLLMQVKSDQSSFKSSPTFIPHDEPNEPKLTLPHVEVEKDSHSTKQVKIELLA
HHHHHHHHEEEEECCCHHHHCCCCCCCCCCCCCCCCEECCCEEECCCCCCHHHHHHHHHH
QLTQELRTPLTSVLGMASVLGREIYGPLTTKQREYLDIIQHSGRYLLSLVNEITELGAID
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
EKASVLNLAPVDIEMLCQQAINTLEEAANRREQDIRLSIEPGRSRIWPLDKDKVRQMLYH
CCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
LIFSVIQFSATGSIVRIHVSYKENALNITVWVSHPWLGDGITDVDPYFRLNSLSVMDLAG
HHHHHHHHCCCCCEEEEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCEECCEEEEEECC
DAAMYSVPPEPKEEIKSLPVTLEKLRSLADSYSDLLAVNPDGDSSKSKGNLSRESLGLLL
CCEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHCCEE
SCQLAELHGGQISIQGSRESGHRYLVNLPLQLAKNPEVSDI
EEEEHHCCCCEEEEECCCCCCCEEEEECCHHHCCCCCCCCC
>Mature Secondary Structure
MVAMVEPENKLFALKDGWVSQDTREQQRLKALSELGLRQPETIPVFEEATQTAAHFLEAP
CEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
ISILGFIDQERHWFKSAVGLSRLGLMNHLAQSRQLLRQESFCTQVVDSHQILVINDTLRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEE
TDPALATGKLIQDYGIRAYLGAPLIDAAGNCLGALAVMDLVPRNFTTRDVEFLQIIARWS
CCCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
MSEFERNRLLMQVKSDQSSFKSSPTFIPHDEPNEPKLTLPHVEVEKDSHSTKQVKIELLA
HHHHHHHHEEEEECCCHHHHCCCCCCCCCCCCCCCCEECCCEEECCCCCCHHHHHHHHHH
QLTQELRTPLTSVLGMASVLGREIYGPLTTKQREYLDIIQHSGRYLLSLVNEITELGAID
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
EKASVLNLAPVDIEMLCQQAINTLEEAANRREQDIRLSIEPGRSRIWPLDKDKVRQMLYH
CCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
LIFSVIQFSATGSIVRIHVSYKENALNITVWVSHPWLGDGITDVDPYFRLNSLSVMDLAG
HHHHHHHHCCCCCEEEEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCEECCEEEEEECC
DAAMYSVPPEPKEEIKSLPVTLEKLRSLADSYSDLLAVNPDGDSSKSKGNLSRESLGLLL
CCEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHCCEE
SCQLAELHGGQISIQGSRESGHRYLVNLPLQLAKNPEVSDI
EEEEHHCCCCEEEEECCCCCCCEEEEECCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA