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The map label for this gene is ubiB [C]

Identifier: 17232452

GI number: 17232452

Start: 5916386

End: 5918398

Strand: Reverse

Name: ubiB [C]

Synonym: all4960

Alternate gene names: 17232452

Gene position: 5918398-5916386 (Counterclockwise)

Preceding gene: 17232454

Following gene: 17232448

Centisome position: 92.28

GC content: 42.87

Gene sequence:

>2013_bases
GTGGCTCTATTCATGACTGTGAAGACACTTCCCCCAAATTCCCGACCGATTGAGGGCGAACTACAGCTAAAGGATACACA
AGCCTTGGTTGTGCGCTCATCAAGACCCGTAAGCTCTGAAAGACCCCAGGTGGTGGTAACTGCAAATCTCGAACCTGAGA
CAATAGTTTACGACCCTGTAGCGGTAGCAGAGCATTATCGTCATCGACCCCTGCAAGTTTTGCGGCGGATTTTTGCTGTG
TTGGGGCCTACTTTCTCCTTTGCCTTTGGGTTGTGGTGGGATATTAAACGGGGAGTAGTCGTCAAAAATGACCGTCGTCG
AGCTATTGAGTTAAAAGAATTATTAACGCAACTGGGGCCTGCTTATATCAAAATTGGTCAAGCCTTATCTACTAGACCAG
ATTTAGTCCCTCCCGTATATTTAGAAGAACTAACAAGGTTACAAGACCAGTTACCACCCTTTCCTAATGAAATTGCTTAC
CAATTTATTCAAGAAGAATTAGGACAGCCACCACAAGAGGTTTACGCTGAACTTTCAGCCCAACCAATTGCGGCTGCTTC
TTTGGGACAAGTTTATAAAGGTAAGTTAAAAACAGGGGAAGAAGTAGCGGTTAAAGTCCAGCGCCCAGATTTACGAGAAC
GAATTACGATTGACTTATATATTTTACGTGGGCTAGCGGCTTGGATACAGAAGAAAGTCAAGAGGGTACGGAGTGACTTA
GTTGGGATTTTGGATGAATTAGGCGATCGCATTTTTGAAGAGATGGATTATATCCACGAAGGTGAAAATGCTGAACGTTT
CTTCCAACTATATGGTCATATGCAAGACGTATATGTACCGAGAATATACTGGGAATATACGAACCGTCGTGTCTTGACGA
TGGAGTGGATCAACGGCACAAAACTGACCCAGACAGAAGAGATTAGCTCCCAAGGGATAGATGCTCGTTATTTGATTGAA
GTTGGTGTGCAGTGTTCCTTAAGGCAACTTTTAGAACATGGCTTCTTTCACGCTGACCCCCATCCTGGTAACTTGTTAGC
CACACCAGACGGTAAACTCGCTTATCTTGACTTTGGGATGATGAGTGAGATTAAACCACCGCAACGTTATGGTTTAATTG
AGGCGATCGTCCACGTAGTTAATCGTGACTTTGAAGGGTTAGCAAAAGATTACGTTAAGTTAGATTTCCTTTCCCCAGAA
ACAGACCTCACCCCAATTATTCCCGCATTTGGCAAAGTTTTCGCTAATGCTCAAGGCGCTAGTGTCGCCGAATTTAACAT
TAAGAGCATCACTGATGAGCTATCAGAATTGATGTATGAGTATCCTTTCCGCGTACCTCCCTACTACGCTTTAATCATTC
GCTCTCTCGTTACCCTGGAAGGGATTGCTATCTATATAGATCCCAACTTTAAAGTTTTGAGCGAGGCTTATCCCTACGTC
GCTAAACGTTTGTTAACCGACCCAGCACCAGAATTAAGAATTTCACTGCGAGACTTGCTTTTTAAAGATGGTAGATTTCG
TTGGAATCGGTTAGAAAACTTATTACGTAATGCGCGGAAAAACCAAGACTACGACCTTAACTTAGTAGTGAATCAAGGTG
TAGATTTTCTCTCATCTGAACGCGGTTCTTTTATTAGAGATAAGTTAGTCGATGAATTTCTCAACGGAATCAATGCTTTA
AGTAAAAATGTGCTGCATAACTTTACCTACCTCCTAAGAGAAAGAGTAGGTATCACAGCCATCAACGAAACTCCAGCCGC
GACAGTTGAGCAACAACAAACCTTAGAACACGTCAAAAATATTTTAAATATTTTGCAAGAAACCCGTGGCTTTGACCCAG
CACAGTTTGCACCTCAAGTGGCTCAGTTGGCTTTCAATCCTGGTGTGCAACGTTTGGGACAGCAAGTTGCTAATCAATTA
TTTCAGAAAGCTACTGTGCGTCTAATTCGGGAATTATTAACAGCAGAAGAGGTCAAGAGTAGTGAAATTGAATACCCCAC
GAGAAAAGTGTGA

Upstream 100 bases:

>100_bases
GGTAAATTATATTCCTAGTCTCTAGTTCTCAATTCCCAAACTAAATTAGCAATTTCCTGTAAAGATATTGTTACAATACT
TAACAAGTTCAATCCGACCG

Downstream 100 bases:

>100_bases
TATCTAGTTCTGCTAGTTCTGACGATATGTTTGGTCTGGGTAGGTAATAGCTAATTGGTCATTTGTCGCACTATACAAAT
TACCAGTTAGCAACTCCAAA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 670; Mature: 669

Protein sequence:

>670_residues
MALFMTVKTLPPNSRPIEGELQLKDTQALVVRSSRPVSSERPQVVVTANLEPETIVYDPVAVAEHYRHRPLQVLRRIFAV
LGPTFSFAFGLWWDIKRGVVVKNDRRRAIELKELLTQLGPAYIKIGQALSTRPDLVPPVYLEELTRLQDQLPPFPNEIAY
QFIQEELGQPPQEVYAELSAQPIAAASLGQVYKGKLKTGEEVAVKVQRPDLRERITIDLYILRGLAAWIQKKVKRVRSDL
VGILDELGDRIFEEMDYIHEGENAERFFQLYGHMQDVYVPRIYWEYTNRRVLTMEWINGTKLTQTEEISSQGIDARYLIE
VGVQCSLRQLLEHGFFHADPHPGNLLATPDGKLAYLDFGMMSEIKPPQRYGLIEAIVHVVNRDFEGLAKDYVKLDFLSPE
TDLTPIIPAFGKVFANAQGASVAEFNIKSITDELSELMYEYPFRVPPYYALIIRSLVTLEGIAIYIDPNFKVLSEAYPYV
AKRLLTDPAPELRISLRDLLFKDGRFRWNRLENLLRNARKNQDYDLNLVVNQGVDFLSSERGSFIRDKLVDEFLNGINAL
SKNVLHNFTYLLRERVGITAINETPAATVEQQQTLEHVKNILNILQETRGFDPAQFAPQVAQLAFNPGVQRLGQQVANQL
FQKATVRLIRELLTAEEVKSSEIEYPTRKV

Sequences:

>Translated_670_residues
MALFMTVKTLPPNSRPIEGELQLKDTQALVVRSSRPVSSERPQVVVTANLEPETIVYDPVAVAEHYRHRPLQVLRRIFAV
LGPTFSFAFGLWWDIKRGVVVKNDRRRAIELKELLTQLGPAYIKIGQALSTRPDLVPPVYLEELTRLQDQLPPFPNEIAY
QFIQEELGQPPQEVYAELSAQPIAAASLGQVYKGKLKTGEEVAVKVQRPDLRERITIDLYILRGLAAWIQKKVKRVRSDL
VGILDELGDRIFEEMDYIHEGENAERFFQLYGHMQDVYVPRIYWEYTNRRVLTMEWINGTKLTQTEEISSQGIDARYLIE
VGVQCSLRQLLEHGFFHADPHPGNLLATPDGKLAYLDFGMMSEIKPPQRYGLIEAIVHVVNRDFEGLAKDYVKLDFLSPE
TDLTPIIPAFGKVFANAQGASVAEFNIKSITDELSELMYEYPFRVPPYYALIIRSLVTLEGIAIYIDPNFKVLSEAYPYV
AKRLLTDPAPELRISLRDLLFKDGRFRWNRLENLLRNARKNQDYDLNLVVNQGVDFLSSERGSFIRDKLVDEFLNGINAL
SKNVLHNFTYLLRERVGITAINETPAATVEQQQTLEHVKNILNILQETRGFDPAQFAPQVAQLAFNPGVQRLGQQVANQL
FQKATVRLIRELLTAEEVKSSEIEYPTRKV
>Mature_669_residues
ALFMTVKTLPPNSRPIEGELQLKDTQALVVRSSRPVSSERPQVVVTANLEPETIVYDPVAVAEHYRHRPLQVLRRIFAVL
GPTFSFAFGLWWDIKRGVVVKNDRRRAIELKELLTQLGPAYIKIGQALSTRPDLVPPVYLEELTRLQDQLPPFPNEIAYQ
FIQEELGQPPQEVYAELSAQPIAAASLGQVYKGKLKTGEEVAVKVQRPDLRERITIDLYILRGLAAWIQKKVKRVRSDLV
GILDELGDRIFEEMDYIHEGENAERFFQLYGHMQDVYVPRIYWEYTNRRVLTMEWINGTKLTQTEEISSQGIDARYLIEV
GVQCSLRQLLEHGFFHADPHPGNLLATPDGKLAYLDFGMMSEIKPPQRYGLIEAIVHVVNRDFEGLAKDYVKLDFLSPET
DLTPIIPAFGKVFANAQGASVAEFNIKSITDELSELMYEYPFRVPPYYALIIRSLVTLEGIAIYIDPNFKVLSEAYPYVA
KRLLTDPAPELRISLRDLLFKDGRFRWNRLENLLRNARKNQDYDLNLVVNQGVDFLSSERGSFIRDKLVDEFLNGINALS
KNVLHNFTYLLRERVGITAINETPAATVEQQQTLEHVKNILNILQETRGFDPAQFAPQVAQLAFNPGVQRLGQQVANQLF
QKATVRLIRELLTAEEVKSSEIEYPTRKV

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=269, Percent_Identity=35.3159851301115, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI40254938, Length=260, Percent_Identity=30.3846153846154, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI217035081, Length=243, Percent_Identity=27.5720164609054, Blast_Score=107, Evalue=5e-23,
Organism=Homo sapiens, GI34147522, Length=402, Percent_Identity=25.6218905472637, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI27363457, Length=290, Percent_Identity=29.6551724137931, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI217416386, Length=276, Percent_Identity=29.3478260869565, Blast_Score=86, Evalue=8e-17,
Organism=Escherichia coli, GI2367309, Length=410, Percent_Identity=28.2926829268293, Blast_Score=169, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17559152, Length=276, Percent_Identity=32.6086956521739, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32565180, Length=288, Percent_Identity=27.0833333333333, Blast_Score=89, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6323282, Length=240, Percent_Identity=30.8333333333333, Blast_Score=110, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6321319, Length=250, Percent_Identity=27.6, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325148, Length=451, Percent_Identity=22.3946784922395, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24662575, Length=282, Percent_Identity=35.4609929078014, Blast_Score=162, Evalue=7e-40,
Organism=Drosophila melanogaster, GI22024280, Length=269, Percent_Identity=31.9702602230483, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI18859849, Length=258, Percent_Identity=27.5193798449612, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 76576; Mature: 76445

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALFMTVKTLPPNSRPIEGELQLKDTQALVVRSSRPVSSERPQVVVTANLEPETIVYDPV
CEEEEEEEECCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCEEEEEECCCCCEEEECCH
AVAEHYRHRPLQVLRRIFAVLGPTFSFAFGLWWDIKRGVVVKNDRRRAIELKELLTQLGP
HHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCH
AYIKIGQALSTRPDLVPPVYLEELTRLQDQLPPFPNEIAYQFIQEELGQPPQEVYAELSA
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCC
QPIAAASLGQVYKGKLKTGEEVAVKVQRPDLRERITIDLYILRGLAAWIQKKVKRVRSDL
CCHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGILDELGDRIFEEMDYIHEGENAERFFQLYGHMQDVYVPRIYWEYTNRRVLTMEWINGT
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCC
KLTQTEEISSQGIDARYLIEVGVQCSLRQLLEHGFFHADPHPGNLLATPDGKLAYLDFGM
CCCCHHHHHHCCCCEEEHHHHCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCEEEEECCH
MSEIKPPQRYGLIEAIVHVVNRDFEGLAKDYVKLDFLSPETDLTPIIPAFGKVFANAQGA
HHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHCCCCCC
SVAEFNIKSITDELSELMYEYPFRVPPYYALIIRSLVTLEGIAIYIDPNFKVLSEAYPYV
CEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
AKRLLTDPAPELRISLRDLLFKDGRFRWNRLENLLRNARKNQDYDLNLVVNQGVDFLSSE
HHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCC
RGSFIRDKLVDEFLNGINALSKNVLHNFTYLLRERVGITAINETPAATVEQQQTLEHVKN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHH
ILNILQETRGFDPAQFAPQVAQLAFNPGVQRLGQQVANQLFQKATVRLIRELLTAEEVKS
HHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SEIEYPTRKV
CCCCCCCCCC
>Mature Secondary Structure 
ALFMTVKTLPPNSRPIEGELQLKDTQALVVRSSRPVSSERPQVVVTANLEPETIVYDPV
EEEEEEEECCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCEEEEEECCCCCEEEECCH
AVAEHYRHRPLQVLRRIFAVLGPTFSFAFGLWWDIKRGVVVKNDRRRAIELKELLTQLGP
HHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCH
AYIKIGQALSTRPDLVPPVYLEELTRLQDQLPPFPNEIAYQFIQEELGQPPQEVYAELSA
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCC
QPIAAASLGQVYKGKLKTGEEVAVKVQRPDLRERITIDLYILRGLAAWIQKKVKRVRSDL
CCHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGILDELGDRIFEEMDYIHEGENAERFFQLYGHMQDVYVPRIYWEYTNRRVLTMEWINGT
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCC
KLTQTEEISSQGIDARYLIEVGVQCSLRQLLEHGFFHADPHPGNLLATPDGKLAYLDFGM
CCCCHHHHHHCCCCEEEHHHHCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCEEEEECCH
MSEIKPPQRYGLIEAIVHVVNRDFEGLAKDYVKLDFLSPETDLTPIIPAFGKVFANAQGA
HHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHCCCCCC
SVAEFNIKSITDELSELMYEYPFRVPPYYALIIRSLVTLEGIAIYIDPNFKVLSEAYPYV
CEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
AKRLLTDPAPELRISLRDLLFKDGRFRWNRLENLLRNARKNQDYDLNLVVNQGVDFLSSE
HHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCC
RGSFIRDKLVDEFLNGINALSKNVLHNFTYLLRERVGITAINETPAATVEQQQTLEHVKN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHH
ILNILQETRGFDPAQFAPQVAQLAFNPGVQRLGQQVANQLFQKATVRLIRELLTAEEVKS
HHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SEIEYPTRKV
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]