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The map label for this gene is yggW [C]

Identifier: 17232448

GI number: 17232448

Start: 5910449

End: 5911639

Strand: Reverse

Name: yggW [C]

Synonym: all4956

Alternate gene names: 17232448

Gene position: 5911639-5910449 (Counterclockwise)

Preceding gene: 17232452

Following gene: 17232447

Centisome position: 92.17

GC content: 43.32

Gene sequence:

>1191_bases
ATGCAAAAAGTTAATGTTCCTAGCCTCGCTAGTTCTGCTTATGTACATATTCCCTTTTGCAGAAGGCGGTGCTTTTATTG
TGATTTCCCGATATTTGTTGTTGGCGATCGCCAACGTGGTGAAACATCTGTTACCATCTCCGGGTATGTCGATGTTCTCT
GTGAAGAAATCGCCATTACACCAGCCTTTGGTCAACCCCTCAAGACCGTATTTTTCGGCGGTGGTACGCCTTCGCTGTTA
TCTACAGAGCAATTAGCACAAATACTAGTAACGCTAGATAAGCAGTTTGGGATTGCGCCTGACGCAGAAATATCTATGGA
GGTAGATCCAGGCACATTTGATCTAGCACATATCCAAGGCTATCGTAGTGTTGGTGTAAATCGGGTCAGTTTGGGTGTAC
AAGCGTTTCAAGAAGAATTGTTAAAAGTAGCTGGGCGATCGCACTCGCTTAAAGATATTTTTGCAGCTATAGACTTGATT
CACCAAGTCGAGATTCCCGAATTTAGCATAGACTTAATTTCTGGCTTACCGCATCAGTCTTTAGATCAATGGCAAGATTC
CCTAGACACAGCCGTTAACATCGCACCCACCCACATATCTATATATGATTTGACAATTGAGCCAGGAACAGCTTTTGGTC
GTTATTACAAACCTGGGGATAATCCCTTACCTACCGATGAAACCACGGTAAAAATGTATCAGATGGGTCAGAAGATTTTG
ACTGGTGGCGATTATGAACATTACGAAATTTCCAACTACGCCAAGCCAGGACACCAGTGTAGACATAACCGAGTTTATTG
GGAAAACCGCCCTTATTACGGCTTTGGTATGGGTGCGGCGAGCTATGTAGAAGGTAAACGCTTTACCCGTCCCCGGAAAA
CAAAGGAGTATTATCAATGGGTGCAAGAGTTGATTGCTAATCACGGTGTGATTGATTGGGAAATTACACCAAAAGCAGAT
GTATTGTTAGAAACGTTAATGTTGGGGTTACGCTTGGCTGATGGTGTGAGTTTAGCAGCACTGACGGAGGAATTTGGCAA
GGAGAAAATACAAGAACTGCATCAATGTCTGCAACCTTATTTTACTCAAGGTTGGGTACAAGTTGTGGGTGATAGGTTGC
GGTTAAGTGATCCCGATGGTTTTTTATTTTCCAATGTGGTGTTAGCCGATTTGTTTAGTCAGTTGGGGTAA

Upstream 100 bases:

>100_bases
TGTCATAGTTACGTCAAAAAACGATAGAAACCTGTAAATAAACTATTTATTTTCATTATTTCTAATTTTCCGTTAATTAA
GTTTATTCTTGTTCACAAAT

Downstream 100 bases:

>100_bases
CAGTAGGAACACTCAAGAGGGGTAAGATCGCGCTATAAAAAGAATAATGAAGAGTAAAAAGCGACGGAACCCCCTGCGCC
AATCACTGGCAGTTTTCCGT

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MQKVNVPSLASSAYVHIPFCRRRCFYCDFPIFVVGDRQRGETSVTISGYVDVLCEEIAITPAFGQPLKTVFFGGGTPSLL
STEQLAQILVTLDKQFGIAPDAEISMEVDPGTFDLAHIQGYRSVGVNRVSLGVQAFQEELLKVAGRSHSLKDIFAAIDLI
HQVEIPEFSIDLISGLPHQSLDQWQDSLDTAVNIAPTHISIYDLTIEPGTAFGRYYKPGDNPLPTDETTVKMYQMGQKIL
TGGDYEHYEISNYAKPGHQCRHNRVYWENRPYYGFGMGAASYVEGKRFTRPRKTKEYYQWVQELIANHGVIDWEITPKAD
VLLETLMLGLRLADGVSLAALTEEFGKEKIQELHQCLQPYFTQGWVQVVGDRLRLSDPDGFLFSNVVLADLFSQLG

Sequences:

>Translated_396_residues
MQKVNVPSLASSAYVHIPFCRRRCFYCDFPIFVVGDRQRGETSVTISGYVDVLCEEIAITPAFGQPLKTVFFGGGTPSLL
STEQLAQILVTLDKQFGIAPDAEISMEVDPGTFDLAHIQGYRSVGVNRVSLGVQAFQEELLKVAGRSHSLKDIFAAIDLI
HQVEIPEFSIDLISGLPHQSLDQWQDSLDTAVNIAPTHISIYDLTIEPGTAFGRYYKPGDNPLPTDETTVKMYQMGQKIL
TGGDYEHYEISNYAKPGHQCRHNRVYWENRPYYGFGMGAASYVEGKRFTRPRKTKEYYQWVQELIANHGVIDWEITPKAD
VLLETLMLGLRLADGVSLAALTEEFGKEKIQELHQCLQPYFTQGWVQVVGDRLRLSDPDGFLFSNVVLADLFSQLG
>Mature_396_residues
MQKVNVPSLASSAYVHIPFCRRRCFYCDFPIFVVGDRQRGETSVTISGYVDVLCEEIAITPAFGQPLKTVFFGGGTPSLL
STEQLAQILVTLDKQFGIAPDAEISMEVDPGTFDLAHIQGYRSVGVNRVSLGVQAFQEELLKVAGRSHSLKDIFAAIDLI
HQVEIPEFSIDLISGLPHQSLDQWQDSLDTAVNIAPTHISIYDLTIEPGTAFGRYYKPGDNPLPTDETTVKMYQMGQKIL
TGGDYEHYEISNYAKPGHQCRHNRVYWENRPYYGFGMGAASYVEGKRFTRPRKTKEYYQWVQELIANHGVIDWEITPKAD
VLLETLMLGLRLADGVSLAALTEEFGKEKIQELHQCLQPYFTQGWVQVVGDRLRLSDPDGFLFSNVVLADLFSQLG

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=269, Percent_Identity=30.8550185873606, Blast_Score=160, Evalue=2e-39,
Organism=Escherichia coli, GI1789325, Length=303, Percent_Identity=39.2739273927393, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI87082341, Length=311, Percent_Identity=28.9389067524116, Blast_Score=135, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 44400; Mature: 44400

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKVNVPSLASSAYVHIPFCRRRCFYCDFPIFVVGDRQRGETSVTISGYVDVLCEEIAIT
CCCCCCCCCCCCCEEEEEHHHCCEEEECCCEEEEECCCCCCEEEEEHHHHHHHHHHHCCC
PAFGQPLKTVFFGGGTPSLLSTEQLAQILVTLDKQFGIAPDAEISMEVDPGTFDLAHIQG
CCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEHHHHCC
YRSVGVNRVSLGVQAFQEELLKVAGRSHSLKDIFAAIDLIHQVEIPEFSIDLISGLPHQS
HHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCH
LDQWQDSLDTAVNIAPTHISIYDLTIEPGTAFGRYYKPGDNPLPTDETTVKMYQMGQKIL
HHHHHHHHHHHEEECCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TGGDYEHYEISNYAKPGHQCRHNRVYWENRPYYGFGMGAASYVEGKRFTRPRKTKEYYQW
CCCCCCCEECCCCCCCCHHHHCCCEEECCCCCEEECCCCHHHHCCCCCCCCCCHHHHHHH
VQELIANHGVIDWEITPKADVLLETLMLGLRLADGVSLAALTEEFGKEKIQELHQCLQPY
HHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FTQGWVQVVGDRLRLSDPDGFLFSNVVLADLFSQLG
HHHHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQKVNVPSLASSAYVHIPFCRRRCFYCDFPIFVVGDRQRGETSVTISGYVDVLCEEIAIT
CCCCCCCCCCCCCEEEEEHHHCCEEEECCCEEEEECCCCCCEEEEEHHHHHHHHHHHCCC
PAFGQPLKTVFFGGGTPSLLSTEQLAQILVTLDKQFGIAPDAEISMEVDPGTFDLAHIQG
CCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEHHHHCC
YRSVGVNRVSLGVQAFQEELLKVAGRSHSLKDIFAAIDLIHQVEIPEFSIDLISGLPHQS
HHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCH
LDQWQDSLDTAVNIAPTHISIYDLTIEPGTAFGRYYKPGDNPLPTDETTVKMYQMGQKIL
HHHHHHHHHHHEEECCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TGGDYEHYEISNYAKPGHQCRHNRVYWENRPYYGFGMGAASYVEGKRFTRPRKTKEYYQW
CCCCCCCEECCCCCCCCHHHHCCCEEECCCCCEEECCCCHHHHCCCCCCCCCCHHHHHHH
VQELIANHGVIDWEITPKADVLLETLMLGLRLADGVSLAALTEEFGKEKIQELHQCLQPY
HHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FTQGWVQVVGDRLRLSDPDGFLFSNVVLADLFSQLG
HHHHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]