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The map label for this gene is glsA [H]

Identifier: 17232266

GI number: 17232266

Start: 5687436

End: 5688359

Strand: Reverse

Name: glsA [H]

Synonym: all4774

Alternate gene names: 17232266

Gene position: 5688359-5687436 (Counterclockwise)

Preceding gene: 17232268

Following gene: 17232263

Centisome position: 88.69

GC content: 43.4

Gene sequence:

>924_bases
GTGAAGGGATTTGATAGACTAGACACCGTGGATTTGTCTAATTGGGTAACATTAGCAAAGACTAAGACAAATTGTGGACG
AGTGGTTGAGCGCATCCCAAAATTAGCTGTGGCTGACACCGCTTGGTTTGCCGTCCACATTTGTTGTCAATCAGGTAAAT
TCTACAGTGAAGGAGATACACAATGTGTATTTCCTCTAATGAGTGTGATTAAGCCTTTTACTTTCCTGTATCTATTGGAA
CACATGGGAGTGGAAAAGGTTTTAAGTTGGGTTGGTACGAAACCATCAGATGCACCTTTTAATTCCTTAGAACAACTAGT
TGCTGATGGTGGATATCCACGGAACCCGATGATTAATAGTGGGGCTATTACTCTCGCTGATAAATTACCAGGAGAGGATG
CTGATCATCGCACTCGCTTTTTCTGCAAATGGCTCAACCAATTGGCTGGTAGTCAGATTCAGTTAGATGAATCTATGCTG
GCTTCTGTCAGATTATCTCGCTCTCCTGCTAATCAGGCGATCGCTAATTATCTTGCAGAAAAAGGTTATTTAGAAGATCT
CGATGTAGCACTTGATACTTACGAGCAGATATGCTGTCTTTCTGGGACGGTTGAAGATTTAGCTTTACTGGGGAAACTCT
TGGCTTTAGAAAGTAGCTCAATATCACCGCAGCATCAACAGCTTGTTAACTCGGTCATGTTGACCTGTGGTTTATATGAA
GCTTCTGCTGAGTATGCTGTCACAATTGGTTTACCGATGAAATCTGGGATTGGTGGGGGTTTACTCGCTATAGTCCCAAC
AGCAGGAGCGATCGCCTGTTATAGCCCAGCTTTAGATAGGATTGGTAATCCTGTGGGAGCGATCGCCTTTGTTGAGGTTT
TATCCCGTTCTCTAGGTCTGTGTGGGAGATTTTCCCACCTTTAG

Upstream 100 bases:

>100_bases
TAATAAAAAATATTTTGTTTTTAAGAGATACAGAGGAGAGGAAAGAAGGTTTAAGGGAAAAATAGGATGACTACGATAAA
TCTTTGGGGCTGTATCTATT

Downstream 100 bases:

>100_bases
CCAAAAACTAACTCTTTGGCTGACCCATCATCAACAAAACGCTGTTCACCAACACCAACTAATTCCACAATCATTTCCCG
TTCTGTGGGGGAAAACTCGC

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKGFDRLDTVDLSNWVTLAKTKTNCGRVVERIPKLAVADTAWFAVHICCQSGKFYSEGDTQCVFPLMSVIKPFTFLYLLE
HMGVEKVLSWVGTKPSDAPFNSLEQLVADGGYPRNPMINSGAITLADKLPGEDADHRTRFFCKWLNQLAGSQIQLDESML
ASVRLSRSPANQAIANYLAEKGYLEDLDVALDTYEQICCLSGTVEDLALLGKLLALESSSISPQHQQLVNSVMLTCGLYE
ASAEYAVTIGLPMKSGIGGGLLAIVPTAGAIACYSPALDRIGNPVGAIAFVEVLSRSLGLCGRFSHL

Sequences:

>Translated_307_residues
MKGFDRLDTVDLSNWVTLAKTKTNCGRVVERIPKLAVADTAWFAVHICCQSGKFYSEGDTQCVFPLMSVIKPFTFLYLLE
HMGVEKVLSWVGTKPSDAPFNSLEQLVADGGYPRNPMINSGAITLADKLPGEDADHRTRFFCKWLNQLAGSQIQLDESML
ASVRLSRSPANQAIANYLAEKGYLEDLDVALDTYEQICCLSGTVEDLALLGKLLALESSSISPQHQQLVNSVMLTCGLYE
ASAEYAVTIGLPMKSGIGGGLLAIVPTAGAIACYSPALDRIGNPVGAIAFVEVLSRSLGLCGRFSHL
>Mature_307_residues
MKGFDRLDTVDLSNWVTLAKTKTNCGRVVERIPKLAVADTAWFAVHICCQSGKFYSEGDTQCVFPLMSVIKPFTFLYLLE
HMGVEKVLSWVGTKPSDAPFNSLEQLVADGGYPRNPMINSGAITLADKLPGEDADHRTRFFCKWLNQLAGSQIQLDESML
ASVRLSRSPANQAIANYLAEKGYLEDLDVALDTYEQICCLSGTVEDLALLGKLLALESSSISPQHQQLVNSVMLTCGLYE
ASAEYAVTIGLPMKSGIGGGLLAIVPTAGAIACYSPALDRIGNPVGAIAFVEVLSRSLGLCGRFSHL

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=285, Percent_Identity=32.9824561403509, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI20336214, Length=280, Percent_Identity=30.3571428571429, Blast_Score=137, Evalue=1e-32,
Organism=Escherichia coli, GI1787804, Length=302, Percent_Identity=34.1059602649007, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1786693, Length=306, Percent_Identity=34.3137254901961, Blast_Score=139, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17507019, Length=295, Percent_Identity=33.5593220338983, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17532727, Length=311, Percent_Identity=29.903536977492, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI193204073, Length=288, Percent_Identity=30.2083333333333, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI193204075, Length=290, Percent_Identity=30, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281363241, Length=300, Percent_Identity=31, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24653162, Length=300, Percent_Identity=31.3333333333333, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281363239, Length=300, Percent_Identity=31.3333333333333, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI116008307, Length=300, Percent_Identity=31.3333333333333, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24653156, Length=300, Percent_Identity=31.3333333333333, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24653164, Length=300, Percent_Identity=31.3333333333333, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24653158, Length=300, Percent_Identity=31.3333333333333, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24653166, Length=300, Percent_Identity=31.3333333333333, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 33145; Mature: 33145

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGFDRLDTVDLSNWVTLAKTKTNCGRVVERIPKLAVADTAWFAVHICCQSGKFYSEGDT
CCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
QCVFPLMSVIKPFTFLYLLEHMGVEKVLSWVGTKPSDAPFNSLEQLVADGGYPRNPMINS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
GAITLADKLPGEDADHRTRFFCKWLNQLAGSQIQLDESMLASVRLSRSPANQAIANYLAE
CCEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHH
KGYLEDLDVALDTYEQICCLSGTVEDLALLGKLLALESSSISPQHQQLVNSVMLTCGLYE
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
ASAEYAVTIGLPMKSGIGGGLLAIVPTAGAIACYSPALDRIGNPVGAIAFVEVLSRSLGL
CCCCEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
CGRFSHL
CHHCCCC
>Mature Secondary Structure
MKGFDRLDTVDLSNWVTLAKTKTNCGRVVERIPKLAVADTAWFAVHICCQSGKFYSEGDT
CCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
QCVFPLMSVIKPFTFLYLLEHMGVEKVLSWVGTKPSDAPFNSLEQLVADGGYPRNPMINS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
GAITLADKLPGEDADHRTRFFCKWLNQLAGSQIQLDESMLASVRLSRSPANQAIANYLAE
CCEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHH
KGYLEDLDVALDTYEQICCLSGTVEDLALLGKLLALESSSISPQHQQLVNSVMLTCGLYE
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
ASAEYAVTIGLPMKSGIGGGLLAIVPTAGAIACYSPALDRIGNPVGAIAFVEVLSRSLGL
CCCCEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
CGRFSHL
CHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]