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The map label for this gene is eda [H]

Identifier: 17232263

GI number: 17232263

Start: 5683594

End: 5684226

Strand: Reverse

Name: eda [H]

Synonym: all4771

Alternate gene names: 17232263

Gene position: 5684226-5683594 (Counterclockwise)

Preceding gene: 17232266

Following gene: 17232262

Centisome position: 88.63

GC content: 46.29

Gene sequence:

>633_bases
ATGTCTACTCAAGATTGGTTATCACAGTTGCAAAAACAGCGAGCGATCGCAGTCATCCGCGCGCCACAGATCGAATTAGG
GTTGCAAATGGCTCTGGCTGTAGCTTCTGGGGGAATGCAGCTAATTGAAATTACCTGGAGTAGCGATCGCCCAGGGGAAT
TAATCGCCCAATTACGTGAGCAGTTACCGGAATGTACTATTGGTACTGGTACACTATTTAATTTGCAGCAACTAGAAGAA
GCGATCGCCTGTGGGGCAGAATTTCTATTTACGCCTCATGTTGACCCAGACATGATCAAAGCATCTGTCATTAAAAACAT
ACCCATCATTCCCGGCGCACTCACCCCCACGGAAATTGTGAGTGCTTGGGCTTATGGTGCAAGTTGTGTCAAAATATTCC
CCGTGCAAGCTGTAGGGGGTGCTGATTATATTAAAAGTCTGCAAGGGCCGTTAGGTCATATTCCCTTAATTCCCACTGGG
GGGGTAACTCTGGAAAATGCCAAAGGACTAATTCAAGCAGGTGCGATCGCTGTTGGTTTGGGTGGGGAGTTATTTCCACA
GCAACTAGTAAAAGAGGAAAATTGGCCAGCGATCGCCCAATTAGCTAAAGACTTAATTCAAGAATTAGCGTAA

Upstream 100 bases:

>100_bases
CATGAAAGTGTCTTGTTCTCCCACTCCCCACTTTCAAGCTAGAAAGCTATATCTATGTCAGTCTGGTAATTGAGAATCGA
ACGCTTCTGCCGCCGTTACA

Downstream 100 bases:

>100_bases
TTTTCAGGATGAAATTATTTAAAAACCACTGTTATAGTTGATTTCTCAAAATCTGCTTTAACTCCATGATTGATGTGTTT
CAACTATGAAATCACTGATT

Product: keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase; 2-keto-4-hydroxyglutarate aldolase; KHG-aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MSTQDWLSQLQKQRAIAVIRAPQIELGLQMALAVASGGMQLIEITWSSDRPGELIAQLREQLPECTIGTGTLFNLQQLEE
AIACGAEFLFTPHVDPDMIKASVIKNIPIIPGALTPTEIVSAWAYGASCVKIFPVQAVGGADYIKSLQGPLGHIPLIPTG
GVTLENAKGLIQAGAIAVGLGGELFPQQLVKEENWPAIAQLAKDLIQELA

Sequences:

>Translated_210_residues
MSTQDWLSQLQKQRAIAVIRAPQIELGLQMALAVASGGMQLIEITWSSDRPGELIAQLREQLPECTIGTGTLFNLQQLEE
AIACGAEFLFTPHVDPDMIKASVIKNIPIIPGALTPTEIVSAWAYGASCVKIFPVQAVGGADYIKSLQGPLGHIPLIPTG
GVTLENAKGLIQAGAIAVGLGGELFPQQLVKEENWPAIAQLAKDLIQELA
>Mature_209_residues
STQDWLSQLQKQRAIAVIRAPQIELGLQMALAVASGGMQLIEITWSSDRPGELIAQLREQLPECTIGTGTLFNLQQLEEA
IACGAEFLFTPHVDPDMIKASVIKNIPIIPGALTPTEIVSAWAYGASCVKIFPVQAVGGADYIKSLQGPLGHIPLIPTGG
VTLENAKGLIQAGAIAVGLGGELFPQQLVKEENWPAIAQLAKDLIQELA

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1788156, Length=184, Percent_Identity=28.804347826087, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI48994954, Length=172, Percent_Identity=31.3953488372093, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.3.16; =4.1.2.14 [H]

Molecular weight: Translated: 22326; Mature: 22195

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQDWLSQLQKQRAIAVIRAPQIELGLQMALAVASGGMQLIEITWSSDRPGELIAQLRE
CCCHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHH
QLPECTIGTGTLFNLQQLEEAIACGAEFLFTPHVDPDMIKASVIKNIPIIPGALTPTEIV
HCCCCCCCCCCCHHHHHHHHHHHCCHHHEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHH
SAWAYGASCVKIFPVQAVGGADYIKSLQGPLGHIPLIPTGGVTLENAKGLIQAGAIAVGL
HHHHCCCCEEEEEEEHCCCCHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHHCEEEEEC
GGELFPQQLVKEENWPAIAQLAKDLIQELA
CCHHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STQDWLSQLQKQRAIAVIRAPQIELGLQMALAVASGGMQLIEITWSSDRPGELIAQLRE
CCHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHH
QLPECTIGTGTLFNLQQLEEAIACGAEFLFTPHVDPDMIKASVIKNIPIIPGALTPTEIV
HCCCCCCCCCCCHHHHHHHHHHHCCHHHEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHH
SAWAYGASCVKIFPVQAVGGADYIKSLQGPLGHIPLIPTGGVTLENAKGLIQAGAIAVGL
HHHHCCCCEEEEEEEHCCCCHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHHCEEEEEC
GGELFPQQLVKEENWPAIAQLAKDLIQELA
CCHHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]