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The map label for this gene is clpP [H]

Identifier: 17231849

GI number: 17231849

Start: 5219511

End: 5220104

Strand: Reverse

Name: clpP [H]

Synonym: all4357

Alternate gene names: 17231849

Gene position: 5220104-5219511 (Counterclockwise)

Preceding gene: 17231850

Following gene: 17231848

Centisome position: 81.39

GC content: 44.28

Gene sequence:

>594_bases
ATGCCTATAGGAGTTCCTAAAGTCCCGTATCGGATGCCAGGTGGTCAATTTACAGATTGGATTAGCATCTACGATCGCCT
ATACCGAGAACGAATTATTTTCTTGGGACGCGACGTTGATGATGAAATTGCTAACCAAATTATCGCCGTCATGTTGTACC
TGGATTCAGAAGACCCAGGTAAGGACATTTATTTGTATATCAATTCCCCCGGTGGGATGGTAACATCCGGTTTGGCAATT
TATGACACAATGCAGCACATCAAATCAGATGTGGTAACCATTTGCGTAGGTTTAGCTGCTTCTATGGGTTCTTTCTTGTT
AGCTGCTGGTACCAAAGGTAAGCGCATGGCATTACCCCATTCACGGATTATGATTCACCAACCTTCTGGTGGAACCCGTG
GACAAGCAACCGATATCGAAATCGAAGCCAGAGAAATTCTACGGATTCGCCACCAGCTCAATCAAATTTATGCCAACAAC
ACCAGTCAACCCCTAGCCAAAATCGAAAAAGATATGGATCGGGACTTTTTTATGTCAGCTCAAGAGGCGATGGAATACGG
TTTGATTGACCGTGTGATTGAAGAACGCGTCTAA

Upstream 100 bases:

>100_bases
CTACCAGCAAGTGTTCTTTAAAAAGTCAGCAGTCAATAGTTATAAAACTAATGACTAATGACTAATGACTAATGACTAAA
TTACAAACGGAGTCAAAAAA

Downstream 100 bases:

>100_bases
ACATGGGGGCAGGGGGCAGGGGAAGCAGGGGAGGCAGGGGGGCAGGGAGCAGGGGGAAAAAGGAATTTACAGAAAGATTT
CCCAGTCCCCAGTCCCCAGT

Product: ATP-dependent Clp protease proteolytic subunit

Products: NA

Alternate protein names: Endopeptidase Clp 2 [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MPIGVPKVPYRMPGGQFTDWISIYDRLYRERIIFLGRDVDDEIANQIIAVMLYLDSEDPGKDIYLYINSPGGMVTSGLAI
YDTMQHIKSDVVTICVGLAASMGSFLLAAGTKGKRMALPHSRIMIHQPSGGTRGQATDIEIEAREILRIRHQLNQIYANN
TSQPLAKIEKDMDRDFFMSAQEAMEYGLIDRVIEERV

Sequences:

>Translated_197_residues
MPIGVPKVPYRMPGGQFTDWISIYDRLYRERIIFLGRDVDDEIANQIIAVMLYLDSEDPGKDIYLYINSPGGMVTSGLAI
YDTMQHIKSDVVTICVGLAASMGSFLLAAGTKGKRMALPHSRIMIHQPSGGTRGQATDIEIEAREILRIRHQLNQIYANN
TSQPLAKIEKDMDRDFFMSAQEAMEYGLIDRVIEERV
>Mature_196_residues
PIGVPKVPYRMPGGQFTDWISIYDRLYRERIIFLGRDVDDEIANQIIAVMLYLDSEDPGKDIYLYINSPGGMVTSGLAIY
DTMQHIKSDVVTICVGLAASMGSFLLAAGTKGKRMALPHSRIMIHQPSGGTRGQATDIEIEAREILRIRHQLNQIYANNT
SQPLAKIEKDMDRDFFMSAQEAMEYGLIDRVIEERV

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=171, Percent_Identity=59.0643274853801, Blast_Score=209, Evalue=9e-55,
Organism=Escherichia coli, GI1786641, Length=174, Percent_Identity=61.4942528735632, Blast_Score=231, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17538017, Length=190, Percent_Identity=52.6315789473684, Blast_Score=193, Evalue=4e-50,
Organism=Drosophila melanogaster, GI20129427, Length=172, Percent_Identity=53.4883720930233, Blast_Score=193, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 22185; Mature: 22054

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00381 CLP_PROTEASE_SER ; PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIGVPKVPYRMPGGQFTDWISIYDRLYRERIIFLGRDVDDEIANQIIAVMLYLDSEDPG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCC
KDIYLYINSPGGMVTSGLAIYDTMQHIKSDVVTICVGLAASMGSFLLAAGTKGKRMALPH
CEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEECCC
SRIMIHQPSGGTRGQATDIEIEAREILRIRHQLNQIYANNTSQPLAKIEKDMDRDFFMSA
CEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHH
QEAMEYGLIDRVIEERV
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PIGVPKVPYRMPGGQFTDWISIYDRLYRERIIFLGRDVDDEIANQIIAVMLYLDSEDPG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCC
KDIYLYINSPGGMVTSGLAIYDTMQHIKSDVVTICVGLAASMGSFLLAAGTKGKRMALPH
CEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEECCC
SRIMIHQPSGGTRGQATDIEIEAREILRIRHQLNQIYANNTSQPLAKIEKDMDRDFFMSA
CEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHH
QEAMEYGLIDRVIEERV
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA