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The map label for this gene is arnT2 [H]

Identifier: 17231839

GI number: 17231839

Start: 5208964

End: 5210511

Strand: Direct

Name: arnT2 [H]

Synonym: alr4347

Alternate gene names: 17231839

Gene position: 5208964-5210511 (Clockwise)

Preceding gene: 17231838

Following gene: 17231843

Centisome position: 81.22

GC content: 39.99

Gene sequence:

>1548_bases
ATGCGCCCAATCACACAAAGAAAATTACTATTAGTTTTGTTGGTTGCTGCTTTGGCTTTGTGGCTCACATTTTTAGGTAA
CTTACCTTTAAGAGATTGGGACGAGGGTACTATAGCACAGGTCGCTCGTGACATTTGGCAGGCTCCAGTTGGTTCTATGC
GTTGGCTTTATCCCACCTTGGCGGGGGAGGCTTATCATAACAAACCCCCTCTAATGCACGTATTAATTGCTTGGGCTTAC
TCTATTGGAGGTGTCAATGAATGGACAACACGTTTTCCTGGCGCATTTATCACTGCCTTGGGAGTACCTTTATTGTACTT
GTTAGGGCGATCGCTTTTTAACCGCAGTTTACCAGCTTTGTTTGCGGCATTAGTTTATTTAACTATGTTGCCTGTGGTAC
GCCACGGAAGACTAGCAATGTTGGATGGTACGCTTATTACCTTTTTCTTATTCGTTTTGTTTTGTCTAGTAAAAGCCCGC
CAAAATCAAAAATATGCCTTAGGTGTGGGTATCGGTTTAGGGCTAATTGCTCTAACTAAAGGGATGATGGTTTTGCTATT
AGGCGGAATTGCTGGTTTGTTTCTTTTAGCAGATAGACAATTAATTTTATTAACTAGCCCCTATTTATGGTCAGGTCTAT
TTTTAGGAAGTGCGCCAGCGATCGCCTGGTATATTGCTCAATGGCAACATTATGGAGGTAGTTTTTTAGAAACCAATTTG
CAATCACAAACCTTTAATCGGCTTTTTCAACCTGTAGAAGGACATAGCGGCCCACCTTGGTACTACGTACTGGAAATACT
CAAATATGGTTTTCCTTGGCTATTGTTTTTACCAGGAGGACTTTATTTAGCTGCAAAAAAGCGTGATACTTCTTGGGGTT
GTTTAATTCTTGTCGGGACAATTGTCTATTTGGTAAGTATTTCTGTGATGAGAACTAAACTACCTTGGTACGTTATGCCA
ATATATCCATTTTTGGCTTTGGCTATTGGTGCTAAATTAGCTGATGTTTGGCAGTACCATCATGTTAAATCAACAACTTG
GGTAGTATTATTTGTCATACTGGCGATCGCAGGTTTAGGCGGCTGCATTTACTTTGTGGCTACTGAACCTCAGCCTGTCC
TAATTGCCATGAGTCTTGTCTTAGCCGTGAGTATGTCTACGGTAGCATGGCTGATTAATCAAGGCGATCGCAACTTTATT
CCAGTTTTATTTGCAGGGATGTATTTAGTTTTAACTATGTTCGTAAGTTCCCAGTCATGGATTTGGGAATTAAACGAAGC
ATTTCCAGTCAAACCAGTTGCCGCATTAATCCGCCAATACGTTTCACCAGGCACCAAGATTTATACTTCTTTTGCCTATA
ATCGCCCTAGTCTAGATTTTTACTGTGATTGTCAAGTTCTGACTAAGCCATCCATTTCCCAGCAAATCGGAAGCAATAAT
CATTATTTGCTTTTGGATAATACAATTTTAGAAAAGATCAACTTATCTAGAAACGAAATTTTAGGAACTGTTGAAAACTT
TACTTTGATTGCTCCCGCTAAAAATTAA

Upstream 100 bases:

>100_bases
CAAGCAGACATACCAGAATTAAAAACACTGAAAACGGTGACAAATATTATGAAATTCCTGCCATTATTCCACTTCTAAAA
CATCGGCTAAAAGTTTTAAT

Downstream 100 bases:

>100_bases
TTTGGTTAAAAATCGAATAATTCGCTATCTTAATACAGTATTTAATTTTGGATAAATCAAATCACACTTGCGGATCACAA
ACCAAAGTACATAACCCAAA

Product: hypothetical protein

Products: NA

Alternate protein names: 4-amino-4-deoxy-L-arabinose lipid A transferase 2; Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase; Undecaprenyl phosphate-alpha-L-Ara4N transferase 2 [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MRPITQRKLLLVLLVAALALWLTFLGNLPLRDWDEGTIAQVARDIWQAPVGSMRWLYPTLAGEAYHNKPPLMHVLIAWAY
SIGGVNEWTTRFPGAFITALGVPLLYLLGRSLFNRSLPALFAALVYLTMLPVVRHGRLAMLDGTLITFFLFVLFCLVKAR
QNQKYALGVGIGLGLIALTKGMMVLLLGGIAGLFLLADRQLILLTSPYLWSGLFLGSAPAIAWYIAQWQHYGGSFLETNL
QSQTFNRLFQPVEGHSGPPWYYVLEILKYGFPWLLFLPGGLYLAAKKRDTSWGCLILVGTIVYLVSISVMRTKLPWYVMP
IYPFLALAIGAKLADVWQYHHVKSTTWVVLFVILAIAGLGGCIYFVATEPQPVLIAMSLVLAVSMSTVAWLINQGDRNFI
PVLFAGMYLVLTMFVSSQSWIWELNEAFPVKPVAALIRQYVSPGTKIYTSFAYNRPSLDFYCDCQVLTKPSISQQIGSNN
HYLLLDNTILEKINLSRNEILGTVENFTLIAPAKN

Sequences:

>Translated_515_residues
MRPITQRKLLLVLLVAALALWLTFLGNLPLRDWDEGTIAQVARDIWQAPVGSMRWLYPTLAGEAYHNKPPLMHVLIAWAY
SIGGVNEWTTRFPGAFITALGVPLLYLLGRSLFNRSLPALFAALVYLTMLPVVRHGRLAMLDGTLITFFLFVLFCLVKAR
QNQKYALGVGIGLGLIALTKGMMVLLLGGIAGLFLLADRQLILLTSPYLWSGLFLGSAPAIAWYIAQWQHYGGSFLETNL
QSQTFNRLFQPVEGHSGPPWYYVLEILKYGFPWLLFLPGGLYLAAKKRDTSWGCLILVGTIVYLVSISVMRTKLPWYVMP
IYPFLALAIGAKLADVWQYHHVKSTTWVVLFVILAIAGLGGCIYFVATEPQPVLIAMSLVLAVSMSTVAWLINQGDRNFI
PVLFAGMYLVLTMFVSSQSWIWELNEAFPVKPVAALIRQYVSPGTKIYTSFAYNRPSLDFYCDCQVLTKPSISQQIGSNN
HYLLLDNTILEKINLSRNEILGTVENFTLIAPAKN
>Mature_515_residues
MRPITQRKLLLVLLVAALALWLTFLGNLPLRDWDEGTIAQVARDIWQAPVGSMRWLYPTLAGEAYHNKPPLMHVLIAWAY
SIGGVNEWTTRFPGAFITALGVPLLYLLGRSLFNRSLPALFAALVYLTMLPVVRHGRLAMLDGTLITFFLFVLFCLVKAR
QNQKYALGVGIGLGLIALTKGMMVLLLGGIAGLFLLADRQLILLTSPYLWSGLFLGSAPAIAWYIAQWQHYGGSFLETNL
QSQTFNRLFQPVEGHSGPPWYYVLEILKYGFPWLLFLPGGLYLAAKKRDTSWGCLILVGTIVYLVSISVMRTKLPWYVMP
IYPFLALAIGAKLADVWQYHHVKSTTWVVLFVILAIAGLGGCIYFVATEPQPVLIAMSLVLAVSMSTVAWLINQGDRNFI
PVLFAGMYLVLTMFVSSQSWIWELNEAFPVKPVAALIRQYVSPGTKIYTSFAYNRPSLDFYCDCQVLTKPSISQQIGSNN
HYLLLDNTILEKINLSRNEILGTVENFTLIAPAKN

Specific function: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG1807

COG function: function code M; 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 83 family [H]

Homologues:

Organism=Escherichia coli, GI1788591, Length=305, Percent_Identity=28.8524590163934, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022839
- InterPro:   IPR003342 [H]

Pfam domain/function: PF02366 PMT [H]

EC number: =2.4.2.43 [H]

Molecular weight: Translated: 57550; Mature: 57550

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPITQRKLLLVLLVAALALWLTFLGNLPLRDWDEGTIAQVARDIWQAPVGSMRWLYPTL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHH
AGEAYHNKPPLMHVLIAWAYSIGGVNEWTTRFPGAFITALGVPLLYLLGRSLFNRSLPAL
CCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
FAALVYLTMLPVVRHGRLAMLDGTLITFFLFVLFCLVKARQNQKYALGVGIGLGLIALTK
HHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
GMMVLLLGGIAGLFLLADRQLILLTSPYLWSGLFLGSAPAIAWYIAQWQHYGGSFLETNL
HHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHCH
QSQTFNRLFQPVEGHSGPPWYYVLEILKYGFPWLLFLPGGLYLAAKKRDTSWGCLILVGT
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCHHHHHHHH
IVYLVSISVMRTKLPWYVMPIYPFLALAIGAKLADVWQYHHVKSTTWVVLFVILAIAGLG
HHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
GCIYFVATEPQPVLIAMSLVLAVSMSTVAWLINQGDRNFIPVLFAGMYLVLTMFVSSQSW
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
IWELNEAFPVKPVAALIRQYVSPGTKIYTSFAYNRPSLDFYCDCQVLTKPSISQQIGSNN
EEECCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEEEECCCCHHHHHCCCC
HYLLLDNTILEKINLSRNEILGTVENFTLIAPAKN
CEEEEEHHHHHHHCCCHHHHHEECCCEEEEECCCC
>Mature Secondary Structure
MRPITQRKLLLVLLVAALALWLTFLGNLPLRDWDEGTIAQVARDIWQAPVGSMRWLYPTL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHH
AGEAYHNKPPLMHVLIAWAYSIGGVNEWTTRFPGAFITALGVPLLYLLGRSLFNRSLPAL
CCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
FAALVYLTMLPVVRHGRLAMLDGTLITFFLFVLFCLVKARQNQKYALGVGIGLGLIALTK
HHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
GMMVLLLGGIAGLFLLADRQLILLTSPYLWSGLFLGSAPAIAWYIAQWQHYGGSFLETNL
HHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHCH
QSQTFNRLFQPVEGHSGPPWYYVLEILKYGFPWLLFLPGGLYLAAKKRDTSWGCLILVGT
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCHHHHHHHH
IVYLVSISVMRTKLPWYVMPIYPFLALAIGAKLADVWQYHHVKSTTWVVLFVILAIAGLG
HHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
GCIYFVATEPQPVLIAMSLVLAVSMSTVAWLINQGDRNFIPVLFAGMYLVLTMFVSSQSW
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
IWELNEAFPVKPVAALIRQYVSPGTKIYTSFAYNRPSLDFYCDCQVLTKPSISQQIGSNN
EEECCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEEEECCCCHHHHHCCCC
HYLLLDNTILEKINLSRNEILGTVENFTLIAPAKN
CEEEEEHHHHHHHCCCHHHHHEECCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA