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The map label for this gene is aapQ [H]

Identifier: 17231657

GI number: 17231657

Start: 5011668

End: 5012594

Strand: Direct

Name: aapQ [H]

Synonym: alr4165

Alternate gene names: 17231657

Gene position: 5011668-5012594 (Clockwise)

Preceding gene: 17231656

Following gene: 17231658

Centisome position: 78.14

GC content: 40.35

Gene sequence:

>927_bases
ATGACCAACGAAAAACCTCCTTTTTGGCGTGATAATCGCTTCTGGTATATTGCTGGGCAATTGATTGCTTTATTTTTAGC
TGCATTTGTAGTAGCTATCCTTTTAGGTAATCTTAACCGCAATTTGCAACGATTGGGCATTCAATTTGGCTTTGATTTCC
TCAAGCAGCAAGCATCTTTTGATATCGGTGAAACCCTGATTGCTTATAAACCAACTGATACTTATAGTTTGGCTTTATGG
GTAGGACTAATTAATTCATTACGAATAGCATTTGTCGGCATCATTCTGACAACAATCGTTGGTATACTTGCGGGGATAGC
TAGATTATCTGATAACTGGCTAGTGCGGAATATTTCACTAGTTTATGTAGAGATATTTCGTAATACACCATTACTTTTAC
AATTGTTGTTTTGGTACTTTGCAGTTTTTTTAGGGCTTCCCAGAGCAGATAACAAAATTTCTCTTGGGGGATTTATTGGT
CTGAGCCAAAACGGATTAGAACTACCTTGGTTCACCTTTTCACCAGAGTTTTCTGCATTACTGCTGGGGCTAATTTTTTA
TACTGGAGCTTTTATTGCGGAAATTGTTCGGGGCGGGATTCAGTCAGTATCCAAAGGACAATGGGAAGCAGGGCGATCGC
TAGGATTAAACCCAAGCTTAATCATGCGCCTAGTTATTTTCCCTCAAGCCTTGCGAGTCATCATTCCGCCACTCACAAGC
CAGTATCTCAATCTCACCAAAAATTCCAGTTTAGCGATCGCCATCGGCTACCCCGATATTTATTTTGTCGCCTCCACCAC
CTTTAATCAAACGGGAAAAGCAGTAGAAGTCATGTTACTCCTAATGCTTACCTATCTCTCTCTCAGTTTGACTATCTCCC
TCATCATGAATGCCTTTAATCGCACCGTACAGATTAAAGAAAGGTAA

Upstream 100 bases:

>100_bases
GGCGGGTTATTATACTCTCCACCATTCCGGTAAAAGAGTAAGGAAAAATGACTATTGACTATCTATATACAGAAATTGCA
CCGCAACGTCTCAATGACCA

Downstream 100 bases:

>100_bases
TGGAGACCGGGAGAAAATTACCTTTGACTAATTACCAATGACTAAACTAACTTGGTTACGCAAAAATCTATTTAGTACTT
GGTATAACAGCCTATTAACT

Product: permease protein of amino acid ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTNEKPPFWRDNRFWYIAGQLIALFLAAFVVAILLGNLNRNLQRLGIQFGFDFLKQQASFDIGETLIAYKPTDTYSLALW
VGLINSLRIAFVGIILTTIVGILAGIARLSDNWLVRNISLVYVEIFRNTPLLLQLLFWYFAVFLGLPRADNKISLGGFIG
LSQNGLELPWFTFSPEFSALLLGLIFYTGAFIAEIVRGGIQSVSKGQWEAGRSLGLNPSLIMRLVIFPQALRVIIPPLTS
QYLNLTKNSSLAIAIGYPDIYFVASTTFNQTGKAVEVMLLLMLTYLSLSLTISLIMNAFNRTVQIKER

Sequences:

>Translated_308_residues
MTNEKPPFWRDNRFWYIAGQLIALFLAAFVVAILLGNLNRNLQRLGIQFGFDFLKQQASFDIGETLIAYKPTDTYSLALW
VGLINSLRIAFVGIILTTIVGILAGIARLSDNWLVRNISLVYVEIFRNTPLLLQLLFWYFAVFLGLPRADNKISLGGFIG
LSQNGLELPWFTFSPEFSALLLGLIFYTGAFIAEIVRGGIQSVSKGQWEAGRSLGLNPSLIMRLVIFPQALRVIIPPLTS
QYLNLTKNSSLAIAIGYPDIYFVASTTFNQTGKAVEVMLLLMLTYLSLSLTISLIMNAFNRTVQIKER
>Mature_307_residues
TNEKPPFWRDNRFWYIAGQLIALFLAAFVVAILLGNLNRNLQRLGIQFGFDFLKQQASFDIGETLIAYKPTDTYSLALWV
GLINSLRIAFVGIILTTIVGILAGIARLSDNWLVRNISLVYVEIFRNTPLLLQLLFWYFAVFLGLPRADNKISLGGFIGL
SQNGLELPWFTFSPEFSALLLGLIFYTGAFIAEIVRGGIQSVSKGQWEAGRSLGLNPSLIMRLVIFPQALRVIIPPLTSQ
YLNLTKNSSLAIAIGYPDIYFVASTTFNQTGKAVEVMLLLMLTYLSLSLTISLIMNAFNRTVQIKER

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4597

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994930, Length=135, Percent_Identity=62.2222222222222, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788226, Length=223, Percent_Identity=33.1838565022422, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787030, Length=220, Percent_Identity=31.8181818181818, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1786874, Length=261, Percent_Identity=31.0344827586207, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1786873, Length=221, Percent_Identity=30.7692307692308, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082239, Length=182, Percent_Identity=35.1648351648352, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788645, Length=230, Percent_Identity=25.6521739130435, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787087, Length=188, Percent_Identity=26.5957446808511, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34473; Mature: 34342

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNEKPPFWRDNRFWYIAGQLIALFLAAFVVAILLGNLNRNLQRLGIQFGFDFLKQQASF
CCCCCCCCEECCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
DIGETLIAYKPTDTYSLALWVGLINSLRIAFVGIILTTIVGILAGIARLSDNWLVRNISL
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHH
VYVEIFRNTPLLLQLLFWYFAVFLGLPRADNKISLGGFIGLSQNGLELPWFTFSPEFSAL
EEEEEHHCCHHHHHHHHHHHHHHHCCCCCCCEEEECEEEECCCCCCCCCEEECCCCHHHH
LLGLIFYTGAFIAEIVRGGIQSVSKGQWEAGRSLGLNPSLIMRLVIFPQALRVIIPPLTS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHH
QYLNLTKNSSLAIAIGYPDIYFVASTTFNQTGKAVEVMLLLMLTYLSLSLTISLIMNAFN
HHHHHCCCCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RTVQIKER
CEEEEECC
>Mature Secondary Structure 
TNEKPPFWRDNRFWYIAGQLIALFLAAFVVAILLGNLNRNLQRLGIQFGFDFLKQQASF
CCCCCCCEECCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
DIGETLIAYKPTDTYSLALWVGLINSLRIAFVGIILTTIVGILAGIARLSDNWLVRNISL
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHH
VYVEIFRNTPLLLQLLFWYFAVFLGLPRADNKISLGGFIGLSQNGLELPWFTFSPEFSAL
EEEEEHHCCHHHHHHHHHHHHHHHCCCCCCCEEEECEEEECCCCCCCCCEEECCCCHHHH
LLGLIFYTGAFIAEIVRGGIQSVSKGQWEAGRSLGLNPSLIMRLVIFPQALRVIIPPLTS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHH
QYLNLTKNSSLAIAIGYPDIYFVASTTFNQTGKAVEVMLLLMLTYLSLSLTISLIMNAFN
HHHHHCCCCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RTVQIKER
CEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]