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The map label for this gene is lytB [H]

Identifier: 17231639

GI number: 17231639

Start: 4990744

End: 4992411

Strand: Direct

Name: lytB [H]

Synonym: alr4147

Alternate gene names: 17231639

Gene position: 4990744-4992411 (Clockwise)

Preceding gene: 17231633

Following gene: 17231641

Centisome position: 77.81

GC content: 41.13

Gene sequence:

>1668_bases
ATGCGACAAAACCACCACTTTATAAAGCAATTGCCACAAGCCGAGCGCCAAAGCACAGAGGGGAAAAATCTGATAGCAGT
AAAACATCCGTTCTGGCGTTTTTCTTACACAGTACTGATGACATTCTGTTTATTGGGATTGACAGGCGCATCGGCGACTG
AAGATAAACTTAAGGATTTAGAACTGAAAATTGGGATTGTACAGCGATTTGGCGAGGAGTCTACAGCTAAACTGCAATTG
GAACCGACAACAGGCGATCGCTTAAAGCTCAAGTTTGCCGAAGGTAACAAAGAGCGAGTTCTCCTAACGGACAAACCTGT
CAAGCTAGAAACAGTGATGCAAGCTTTACCCAAACCAGCAATTGCAGAGGTTGTGGTTTTAGGTACATATCGCACCTACG
AAACGGCGGAATACAGTGCTGAAAATTGGCGTAAGCAAGGAATAGAGGTAGAAATAGCCCAGCCGGATCGTTGGCAAGTT
TGGGCAAAACGGGATGTGTATAATACCCCCTTACTACGTCGCTTGTTATTCCAGAACATCAAAGCCGCAAGTAATAATTT
GGCTTACATTGACACAAAAGTTTTGCCGAAAGTACCAAAAATAAGTTGGACTGTGAATGGTACGAGCTACACTCCAAACC
ATGTAGAGGTTAGCACAGTTAAAAACTTAATTCGGTTGAAAAAAGGCGAAAAATTAAATACTTCTCGACTTTATTCTGGG
CGGATTAATTTTCAGCCGAATGCTTATGGTACTTACACTCTAGTAAATCAAGTATCATTAGAGACTTATTTACGTGGTGT
TGTACCTCATGAAATTGGCACTAATGCCCCAACTGCTGCTGTTGAAGCACAAGCAATTTTAGCTCGGACTTATGCTCTAA
GAAATTTGCGTAGATTTGCTATAGATAATTATCAATTATGTGCTAATACTCACTGCCAAGTTTATTATGGGTTGGGTGGT
ACAGATACTAGGATAGATAAAGCGATCGCCGCAACCAGAGGTATGGTACTTACCTATAACAATGAGCTAATAGATGCTCT
TTATTCTTCTACCACTGGCGGAATTACTGCCTCATTCAGTGATGTTTGGAACGGAGAGGATCGGCCTTACTTACGGCCAG
TAGTAGATGCACCTAATAGTGTTTGGGACTTCTCCAAACAAAATTTAAAAGACGAAAGGAACTTTCAGAGATTTATTACC
TTGCAACAAGGATTTAACGAAAGTAGTTGGGATGTGTTTCGTTGGTATAAAGAAACACCTCTTAATGAAATAGTCAAAGA
CTTGCAAAAGTTTCTCCGGGCAAAAAATAGCCCTTATGCTAAATTCCAAACCATCCAGGCAATGGCCATTACCAATCGCA
GTAAAAGCGGAAGGATACTGGAATTAGCAGTAAAGACAGATATTGGCATTTTTACCCTGCACAAAGATGAAGTGCGTAGT
GCCTTTGCTGCGCCAAGAAGCACGCTTTTTTACATAGTACCCCTTAACAAAGGCAAAGAAGAGTTGTGGGGATACGCTTT
TATTGGTGGTGGCTTAGGACACGGAGTTGGCTTAAGTCAAACTGGCGCTCAAACTTTAGCCAAACTAGGTTGGTCTAGCA
ACAAAATTCTCCAATTTTATTATCCTGGTACACAACTTCAAAGCCTGAATGAAGAAATCAAGTTTTAA

Upstream 100 bases:

>100_bases
CTAGTTCCTTTTCGTATCTCTATATAAATCATAGTCATTATGACTTCGTTTTGCAACTTTTTCTAGAGCAAAACCGGTAA
GGGTATTATTTGGAGCGTTC

Downstream 100 bases:

>100_bases
TTGGATGTAGACACAGAGTGAAAAAACAGAAAGGCTAGGGACTAGTCTGTAGCTGCTAGCCTCTAGCCTCTATTTTCCAA
GCTAACTTGACTCTTAGTAG

Product: amidase enhancer

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP76; CWBP76; Modifier protein of major autolysin [H]

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MRQNHHFIKQLPQAERQSTEGKNLIAVKHPFWRFSYTVLMTFCLLGLTGASATEDKLKDLELKIGIVQRFGEESTAKLQL
EPTTGDRLKLKFAEGNKERVLLTDKPVKLETVMQALPKPAIAEVVVLGTYRTYETAEYSAENWRKQGIEVEIAQPDRWQV
WAKRDVYNTPLLRRLLFQNIKAASNNLAYIDTKVLPKVPKISWTVNGTSYTPNHVEVSTVKNLIRLKKGEKLNTSRLYSG
RINFQPNAYGTYTLVNQVSLETYLRGVVPHEIGTNAPTAAVEAQAILARTYALRNLRRFAIDNYQLCANTHCQVYYGLGG
TDTRIDKAIAATRGMVLTYNNELIDALYSSTTGGITASFSDVWNGEDRPYLRPVVDAPNSVWDFSKQNLKDERNFQRFIT
LQQGFNESSWDVFRWYKETPLNEIVKDLQKFLRAKNSPYAKFQTIQAMAITNRSKSGRILELAVKTDIGIFTLHKDEVRS
AFAAPRSTLFYIVPLNKGKEELWGYAFIGGGLGHGVGLSQTGAQTLAKLGWSSNKILQFYYPGTQLQSLNEEIKF

Sequences:

>Translated_555_residues
MRQNHHFIKQLPQAERQSTEGKNLIAVKHPFWRFSYTVLMTFCLLGLTGASATEDKLKDLELKIGIVQRFGEESTAKLQL
EPTTGDRLKLKFAEGNKERVLLTDKPVKLETVMQALPKPAIAEVVVLGTYRTYETAEYSAENWRKQGIEVEIAQPDRWQV
WAKRDVYNTPLLRRLLFQNIKAASNNLAYIDTKVLPKVPKISWTVNGTSYTPNHVEVSTVKNLIRLKKGEKLNTSRLYSG
RINFQPNAYGTYTLVNQVSLETYLRGVVPHEIGTNAPTAAVEAQAILARTYALRNLRRFAIDNYQLCANTHCQVYYGLGG
TDTRIDKAIAATRGMVLTYNNELIDALYSSTTGGITASFSDVWNGEDRPYLRPVVDAPNSVWDFSKQNLKDERNFQRFIT
LQQGFNESSWDVFRWYKETPLNEIVKDLQKFLRAKNSPYAKFQTIQAMAITNRSKSGRILELAVKTDIGIFTLHKDEVRS
AFAAPRSTLFYIVPLNKGKEELWGYAFIGGGLGHGVGLSQTGAQTLAKLGWSSNKILQFYYPGTQLQSLNEEIKF
>Mature_555_residues
MRQNHHFIKQLPQAERQSTEGKNLIAVKHPFWRFSYTVLMTFCLLGLTGASATEDKLKDLELKIGIVQRFGEESTAKLQL
EPTTGDRLKLKFAEGNKERVLLTDKPVKLETVMQALPKPAIAEVVVLGTYRTYETAEYSAENWRKQGIEVEIAQPDRWQV
WAKRDVYNTPLLRRLLFQNIKAASNNLAYIDTKVLPKVPKISWTVNGTSYTPNHVEVSTVKNLIRLKKGEKLNTSRLYSG
RINFQPNAYGTYTLVNQVSLETYLRGVVPHEIGTNAPTAAVEAQAILARTYALRNLRRFAIDNYQLCANTHCQVYYGLGG
TDTRIDKAIAATRGMVLTYNNELIDALYSSTTGGITASFSDVWNGEDRPYLRPVVDAPNSVWDFSKQNLKDERNFQRFIT
LQQGFNESSWDVFRWYKETPLNEIVKDLQKFLRAKNSPYAKFQTIQAMAITNRSKSGRILELAVKTDIGIFTLHKDEVRS
AFAAPRSTLFYIVPLNKGKEELWGYAFIGGGLGHGVGLSQTGAQTLAKLGWSSNKILQFYYPGTQLQSLNEEIKF

Specific function: Possibly involved in cell wall metabolism during spore formation. Enhances the amidase activity approximately threefold [H]

COG id: COG2385

COG function: function code D; Sporulation protein and related proteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein. Secreted, cell wall. Note=Cell wall localization shown in PubMed:11987133 [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007253
- InterPro:   IPR013486
- InterPro:   IPR013693 [H]

Pfam domain/function: PF04122 CW_binding_2; PF08486 SpoIID [H]

EC number: NA

Molecular weight: Translated: 62878; Mature: 62878

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQNHHFIKQLPQAERQSTEGKNLIAVKHPFWRFSYTVLMTFCLLGLTGASATEDKLKDL
CCCCCHHHHHCCHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ELKIGIVQRFGEESTAKLQLEPTTGDRLKLKFAEGNKERVLLTDKPVKLETVMQALPKPA
HEEEEHHHHCCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEECCCCHHHHHHHHCCCCC
IAEVVVLGTYRTYETAEYSAENWRKQGIEVEIAQPDRWQVWAKRDVYNTPLLRRLLFQNI
CEEEEEEECCCCCCCCHHCHHHHHHCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHH
KAASNNLAYIDTKVLPKVPKISWTVNGTSYTPNHVEVSTVKNLIRLKKGEKLNTSRLYSG
HHCCCCEEEEEHHHCCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEEC
RINFQPNAYGTYTLVNQVSLETYLRGVVPHEIGTNAPTAAVEAQAILARTYALRNLRRFA
EEEECCCCCEEEEEHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IDNYQLCANTHCQVYYGLGGTDTRIDKAIAATRGMVLTYNNELIDALYSSTTGGITASFS
CCCEEEECCCCEEEEECCCCCCHHHHHHHHHHCCEEEEECHHHHHHHHHCCCCCEEEEHH
DVWNGEDRPYLRPVVDAPNSVWDFSKQNLKDERNFQRFITLQQGFNESSWDVFRWYKETP
HHCCCCCCCCCCHHHCCCCHHHHCCHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC
LNEIVKDLQKFLRAKNSPYAKFQTIQAMAITNRSKSGRILELAVKTDIGIFTLHKDEVRS
HHHHHHHHHHHHHCCCCCCHHHHHEEEEEEECCCCCCCEEEEEEECCCEEEEEEHHHHHH
AFAAPRSTLFYIVPLNKGKEELWGYAFIGGGLGHGVGLSQTGAQTLAKLGWSSNKILQFY
HHCCCCCEEEEEEECCCCHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEE
YPGTQLQSLNEEIKF
ECCHHHHHHHHHHCC
>Mature Secondary Structure
MRQNHHFIKQLPQAERQSTEGKNLIAVKHPFWRFSYTVLMTFCLLGLTGASATEDKLKDL
CCCCCHHHHHCCHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ELKIGIVQRFGEESTAKLQLEPTTGDRLKLKFAEGNKERVLLTDKPVKLETVMQALPKPA
HEEEEHHHHCCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEECCCCHHHHHHHHCCCCC
IAEVVVLGTYRTYETAEYSAENWRKQGIEVEIAQPDRWQVWAKRDVYNTPLLRRLLFQNI
CEEEEEEECCCCCCCCHHCHHHHHHCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHH
KAASNNLAYIDTKVLPKVPKISWTVNGTSYTPNHVEVSTVKNLIRLKKGEKLNTSRLYSG
HHCCCCEEEEEHHHCCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEEC
RINFQPNAYGTYTLVNQVSLETYLRGVVPHEIGTNAPTAAVEAQAILARTYALRNLRRFA
EEEECCCCCEEEEEHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IDNYQLCANTHCQVYYGLGGTDTRIDKAIAATRGMVLTYNNELIDALYSSTTGGITASFS
CCCEEEECCCCEEEEECCCCCCHHHHHHHHHHCCEEEEECHHHHHHHHHCCCCCEEEEHH
DVWNGEDRPYLRPVVDAPNSVWDFSKQNLKDERNFQRFITLQQGFNESSWDVFRWYKETP
HHCCCCCCCCCCHHHCCCCHHHHCCHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC
LNEIVKDLQKFLRAKNSPYAKFQTIQAMAITNRSKSGRILELAVKTDIGIFTLHKDEVRS
HHHHHHHHHHHHHCCCCCCHHHHHEEEEEEECCCCCCCEEEEEEECCCEEEEEEHHHHHH
AFAAPRSTLFYIVPLNKGKEELWGYAFIGGGLGHGVGLSQTGAQTLAKLGWSSNKILQFY
HHCCCCCEEEEEEECCCCHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEE
YPGTQLQSLNEEIKF
ECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1357079; 1356138; 9384377 [H]