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The map label for this gene is petH [H]

Identifier: 17231613

GI number: 17231613

Start: 4964228

End: 4965550

Strand: Reverse

Name: petH [H]

Synonym: all4121

Alternate gene names: 17231613

Gene position: 4965550-4964228 (Counterclockwise)

Preceding gene: 17231614

Following gene: 17231612

Centisome position: 77.42

GC content: 44.29

Gene sequence:

>1323_bases
ATGTCTAATCAAGGTGCTTTTGATGGTGCTGCCAACGTAGAATCAGGTAGCCGCGTCTTCGTTTACGAAGTGGTGGGTAT
GCGTCAGAACGAAGAAACTGATCAAACGAACTACCCAATTCGTAAAAGTGGCAGTGTGTTCATTAGAGTGCCTTACAACC
GCATGAATCAAGAAATGCAGCGTATCACTCGACTAGGCGGCAAGATTGTTAGCATTCAAACAGTAAGCGCACTACAACAA
CTCAATGGTAGAACTACCATTGCAACAGTAACAGATGCGTCTAGTGAGATTGCTAAGTCTGAGGGGAATGGTAAAGCCAC
ACCTGTAAAAACTGATAGTGGAGCTAAAGGCTTCGCTAAACCACCAGCTGAAGAACAGCTTAAGAAAAAAGACAACAAAG
GCAACACCATGACTCAAGCGAAAGCCAAACACGCTGATGTTCCTGTTAATCTTTACCGTCCCAATGCTCCATTTATTGGT
AAGGTAATCTCTAATGAACCACTGGTAAAAGAAGGCGGGATAGGTATTGTTCAGCACATTAAATTTGATCTAACTGGTGG
TAACTTAAAGTACATCGAAGGTCAAAGTATTGGTATCATTCCACCAGGAGTGGACAAGAACGGCAAGCCGGAAAAATTGA
GACTCTACTCCATTGCCTCGACCCGTCACGGCGATGATGTGGATGATAAAACCATCTCACTGTGCGTCCGTCAATTAGAG
TACAAACATCCAGAAAGCGGCGAAACAGTTTACGGTGTTTGTTCTACTTACTTGACTCACATTGAACCAGGTTCAGAAGT
GAAAATCACTGGGCCTGTGGGTAAAGAAATGCTGTTACCCGATGATCCTGAAGCTAATGTCATCATGTTGGCAACAGGTA
CTGGTATTGCGCCTATGCGGACTTACCTGTGGCGGATGTTCAAGGATGCAGAAAGAGCTGCTAACCCAGAATATCAATTC
AAAGGATTCTCTTGGTTAGTCTTTGGTGTTCCTACAACTCCTAACATTCTTTATAAAGAAGAACTGGAAGAAATCCAACA
AAAATATCCCGATAACTTCCGCCTAACTTACGCTATCAGCCGGGAGCAAAAGAATCCCCAAGGTGGCAGAATGTACATCC
AAGACCGTGTGGCAGAACACGCTGATGAACTGTGGCAATTAATCAAGAATGAAAAAACCCACACCTACATCTGTGGTTTG
CGCGGTATGGAAGAGGGCATTGATGCTGCTTTAAGTGCTGCGGCTGCGAAAGAAGGTGTTACCTGGAGTGATTACCAAAA
AGACCTCAAGAAAGCTGGTCGCTGGCACGTAGAAACATACTAA

Upstream 100 bases:

>100_bases
CTAGTTTTAGTAACGAAAAATCCGATAAACTAAAGCTGGCTTGTGAAGAGAAAAGCTTTTTTGAGAAACGGTTAAGTTAA
AGATCGGAGTGGTAGAAGGA

Downstream 100 bases:

>100_bases
GTTGGTTATTGGTCAATTGTCAGTTGTCAGTCGCAAAATACAAACAACTGACAACTGAGGACAAACAACTAACAAAATTG
ATGAATTTGTAGGGTGGGCA

Product: ferredoxin--NADP(+) reductase

Products: NA

Alternate protein names: FNR [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSNQGAFDGAANVESGSRVFVYEVVGMRQNEETDQTNYPIRKSGSVFIRVPYNRMNQEMQRITRLGGKIVSIQTVSALQQ
LNGRTTIATVTDASSEIAKSEGNGKATPVKTDSGAKGFAKPPAEEQLKKKDNKGNTMTQAKAKHADVPVNLYRPNAPFIG
KVISNEPLVKEGGIGIVQHIKFDLTGGNLKYIEGQSIGIIPPGVDKNGKPEKLRLYSIASTRHGDDVDDKTISLCVRQLE
YKHPESGETVYGVCSTYLTHIEPGSEVKITGPVGKEMLLPDDPEANVIMLATGTGIAPMRTYLWRMFKDAERAANPEYQF
KGFSWLVFGVPTTPNILYKEELEEIQQKYPDNFRLTYAISREQKNPQGGRMYIQDRVAEHADELWQLIKNEKTHTYICGL
RGMEEGIDAALSAAAAKEGVTWSDYQKDLKKAGRWHVETY

Sequences:

>Translated_440_residues
MSNQGAFDGAANVESGSRVFVYEVVGMRQNEETDQTNYPIRKSGSVFIRVPYNRMNQEMQRITRLGGKIVSIQTVSALQQ
LNGRTTIATVTDASSEIAKSEGNGKATPVKTDSGAKGFAKPPAEEQLKKKDNKGNTMTQAKAKHADVPVNLYRPNAPFIG
KVISNEPLVKEGGIGIVQHIKFDLTGGNLKYIEGQSIGIIPPGVDKNGKPEKLRLYSIASTRHGDDVDDKTISLCVRQLE
YKHPESGETVYGVCSTYLTHIEPGSEVKITGPVGKEMLLPDDPEANVIMLATGTGIAPMRTYLWRMFKDAERAANPEYQF
KGFSWLVFGVPTTPNILYKEELEEIQQKYPDNFRLTYAISREQKNPQGGRMYIQDRVAEHADELWQLIKNEKTHTYICGL
RGMEEGIDAALSAAAAKEGVTWSDYQKDLKKAGRWHVETY
>Mature_439_residues
SNQGAFDGAANVESGSRVFVYEVVGMRQNEETDQTNYPIRKSGSVFIRVPYNRMNQEMQRITRLGGKIVSIQTVSALQQL
NGRTTIATVTDASSEIAKSEGNGKATPVKTDSGAKGFAKPPAEEQLKKKDNKGNTMTQAKAKHADVPVNLYRPNAPFIGK
VISNEPLVKEGGIGIVQHIKFDLTGGNLKYIEGQSIGIIPPGVDKNGKPEKLRLYSIASTRHGDDVDDKTISLCVRQLEY
KHPESGETVYGVCSTYLTHIEPGSEVKITGPVGKEMLLPDDPEANVIMLATGTGIAPMRTYLWRMFKDAERAANPEYQFK
GFSWLVFGVPTTPNILYKEELEEIQQKYPDNFRLTYAISREQKNPQGGRMYIQDRVAEHADELWQLIKNEKTHTYICGLR
GMEEGIDAALSAAAAKEGVTWSDYQKDLKKAGRWHVETY

Specific function: Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. The Flavo-Protein Component Catalyzes The Electron Flow From Nadph -> FAD -> Fmn To The Hemoprotein Compo

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=May be bound to the thylakoid membrane or anchored to the thylakoid-bound phycobilisomes [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI40254422, Length=239, Percent_Identity=30.1255230125523, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI24041029, Length=241, Percent_Identity=29.4605809128631, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI10835173, Length=212, Percent_Identity=29.7169811320755, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1789123, Length=217, Percent_Identity=32.7188940092166, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17554134, Length=236, Percent_Identity=30.0847457627119, Blast_Score=75, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321832, Length=174, Percent_Identity=29.8850574712644, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI78706872, Length=238, Percent_Identity=30.2521008403361, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24583543, Length=238, Percent_Identity=30.2521008403361, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI78706876, Length=238, Percent_Identity=30.2521008403361, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17137192, Length=191, Percent_Identity=33.5078534031414, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24582192, Length=190, Percent_Identity=32.6315789473684, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012146
- InterPro:   IPR015701
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR008213
- InterPro:   IPR017938 [H]

Pfam domain/function: PF01383 CpcD; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 48839; Mature: 48708

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQGAFDGAANVESGSRVFVYEVVGMRQNEETDQTNYPIRKSGSVFIRVPYNRMNQEMQ
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEECCCCEEEEECHHHHHHHHH
RITRLGGKIVSIQTVSALQQLNGRTTIATVTDASSEIAKSEGNGKATPVKTDSGAKGFAK
HHHHHCCEEEEEHHHHHHHHCCCCEEEEEEECCHHHHHHCCCCCCCCCEECCCCCCCCCC
PPAEEQLKKKDNKGNTMTQAKAKHADVPVNLYRPNAPFIGKVISNEPLVKEGGIGIVQHI
CCHHHHHHHCCCCCCCCHHHHHHCCCCCEEEECCCCCHHHHHHCCCCCEECCCCEEEEEE
KFDLTGGNLKYIEGQSIGIIPPGVDKNGKPEKLRLYSIASTRHGDDVDDKTISLCVRQLE
EEEECCCCEEEECCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHH
YKHPESGETVYGVCSTYLTHIEPGSEVKITGPVGKEMLLPDDPEANVIMLATGTGIAPMR
CCCCCCCCEEHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHH
TYLWRMFKDAERAANPEYQFKGFSWLVFGVPTTPNILYKEELEEIQQKYPDNFRLTYAIS
HHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCEEEHHHHHHHHHHCCCCEEEEEEEE
REQKNPQGGRMYIQDRVAEHADELWQLIKNEKTHTYICGLRGMEEGIDAALSAAAAKEGV
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
TWSDYQKDLKKAGRWHVETY
CHHHHHHHHHHCCCEEECCC
>Mature Secondary Structure 
SNQGAFDGAANVESGSRVFVYEVVGMRQNEETDQTNYPIRKSGSVFIRVPYNRMNQEMQ
CCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEECCCCEEEEECHHHHHHHHH
RITRLGGKIVSIQTVSALQQLNGRTTIATVTDASSEIAKSEGNGKATPVKTDSGAKGFAK
HHHHHCCEEEEEHHHHHHHHCCCCEEEEEEECCHHHHHHCCCCCCCCCEECCCCCCCCCC
PPAEEQLKKKDNKGNTMTQAKAKHADVPVNLYRPNAPFIGKVISNEPLVKEGGIGIVQHI
CCHHHHHHHCCCCCCCCHHHHHHCCCCCEEEECCCCCHHHHHHCCCCCEECCCCEEEEEE
KFDLTGGNLKYIEGQSIGIIPPGVDKNGKPEKLRLYSIASTRHGDDVDDKTISLCVRQLE
EEEECCCCEEEECCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHH
YKHPESGETVYGVCSTYLTHIEPGSEVKITGPVGKEMLLPDDPEANVIMLATGTGIAPMR
CCCCCCCCEEHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHH
TYLWRMFKDAERAANPEYQFKGFSWLVFGVPTTPNILYKEELEEIQQKYPDNFRLTYAIS
HHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCEEEHHHHHHHHHHCCCCEEEEEEEE
REQKNPQGGRMYIQDRVAEHADELWQLIKNEKTHTYICGLRGMEEGIDAALSAAAAKEGV
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
TWSDYQKDLKKAGRWHVETY
CHHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8343609; 2124680; 3124746; 8890910; 9922134; 10651039; 11053838 [H]