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The map label for this gene is comM [H]

Identifier: 17231580

GI number: 17231580

Start: 4925883

End: 4927412

Strand: Direct

Name: comM [H]

Synonym: alr4088

Alternate gene names: 17231580

Gene position: 4925883-4927412 (Clockwise)

Preceding gene: 17231578

Following gene: 17231585

Centisome position: 76.8

GC content: 46.14

Gene sequence:

>1530_bases
ATGCTTGCTAGAGTCTGGAGTGCATCAATTGTCGGCATCGATGCCGTGAAAGTGGGCGTAGAAGTCGATATATCGGGGGG
TTTGCCGGGAATCGTAGTTTTGGGGCTACCAGATTCAGCCGTTCAGGAATCAAAAGAAAGAGTCAAAGCTACTCTCAAAA
ATGCGGGTTTTGCCTTCCCAATGCGGAAAATAGTGATTAACTTGACTCCAGCAGACTTACGCAAGGAAGGCCCCTGTTTC
GATTTGCCTATTAGTATAGGGATTTTAGCTGCTTCTGAACAGGTTAAGTCTGACTTGTTAGGAGATTATCTTTTTTTGGG
TGAAGTTTCTCTCGATGGCAGCTTACGTCCTGTGGCTGGGGTTTTACCGATCGCTGCTACTGCCAAAAAAATGGGGATTG
CAGGGTTAGTTGTACCTGTAGATAATGCTCAAGAAGCTTCAGTGGTGGAGGGTTTGGAGGTGCATGGCTGCAAGAATGTG
TCTGAGGTTGTGGATTTATTAAATAACCCTGGCAAGCATCAGCCTGTAAAGTTAGATGAATCACAAGAACTCACACCAAT
ATCTTATGCGATCGCCGACTTAAAGGACGTAAAAGGACAAGCGCATGGTCGTCGTGCTTTAGAAATTGCGGCGGCTGGCG
GACATAATTTGATTTTTGTCGGCCCTCCTGGTAGTGGGAAAACCATGCTAGCAAGGCGCTTACCTGGAATTTTACCACCT
CTGAGTTTTGCCGAAGCCTTGGAAGTGACTCGCATTCACTCTGTGGCTGGGTTGTTGAAAAATCGTGGTTCCTTAGTCCG
CGATCGCCCTTTCCGTAGTCCTCACCATTCAGCCTCCGGGCCTTCTCTTGTCGGTGGTGGTGGTTTTCCTCGTCCTGGTG
AAATCTCTCTATCACACAGAGGGATTCTTTTCCTAGACGAGTTAACAGAGTTTAAACGTGATGTTTTAGAATTTCTCCGC
CAGCCTTTAGAAGATGGTTATGTCACCATTTCTCGTACTAGACAATCTGTAATGTTCCCCGCACAGTTTACTTTGGTGGC
CAGTACCAATCCCTGTCCTTGTGGTTATTACGGTGATACTATTCAACAGTGTACCTGTTCACCAAGACAACGAGAGCAGT
ATTGGGCAAAGCTTTCTGGCCCATTAATGGATCGAATTGATTTGCAAGTAGCTGTCAATCGCTTGAAACCAGAAGAAATC
ACCCAACAGCCTACAGGAGAAGAATCCGTTTCTGTGCGGGAAAGAGTACAAAAAGCGCGAGATCGCGCCATTAACCGCTT
TAAAGACGAGCCTAATCTGCGTTGTAATGCCCAAATGCAGAGTCGTCACTTGCAAACATGGTGCAAACTAGATGATGGTA
GTCGCAGCTTATTAGAAGCGGCAATTAAGAAATTGGGTTTATCTGCTAGAGCAAGCGATCGCATTCTGAAAGTAGCCCGG
ACTATTGCAGATTTGGCTGGTGAAGACGAGCTAAAACCTAATCATGTAGCAGAAGCAATTCAGTATCGGACTATAGACAG
AATGCAGTGA

Upstream 100 bases:

>100_bases
TTTGCTGAAAATGGTCTCTGTGGTTTCACTCATGCGGTTATCAGAACTCATCTGCTAGAGATTCTAAAGGGTTACTGTCC
ATCTAAGAAATATTTAGCCA

Downstream 100 bases:

>100_bases
TAGCTAAGTGATTACTGAATTATCAGGGAAGTCAAAAGAACAATTTATATCTTGTTAACTGGCTTTCAATGGCTCCTGTG
AGAATTTTATTGAGTTCTTT

Product: competence protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MLARVWSASIVGIDAVKVGVEVDISGGLPGIVVLGLPDSAVQESKERVKATLKNAGFAFPMRKIVINLTPADLRKEGPCF
DLPISIGILAASEQVKSDLLGDYLFLGEVSLDGSLRPVAGVLPIAATAKKMGIAGLVVPVDNAQEASVVEGLEVHGCKNV
SEVVDLLNNPGKHQPVKLDESQELTPISYAIADLKDVKGQAHGRRALEIAAAGGHNLIFVGPPGSGKTMLARRLPGILPP
LSFAEALEVTRIHSVAGLLKNRGSLVRDRPFRSPHHSASGPSLVGGGGFPRPGEISLSHRGILFLDELTEFKRDVLEFLR
QPLEDGYVTISRTRQSVMFPAQFTLVASTNPCPCGYYGDTIQQCTCSPRQREQYWAKLSGPLMDRIDLQVAVNRLKPEEI
TQQPTGEESVSVRERVQKARDRAINRFKDEPNLRCNAQMQSRHLQTWCKLDDGSRSLLEAAIKKLGLSARASDRILKVAR
TIADLAGEDELKPNHVAEAIQYRTIDRMQ

Sequences:

>Translated_509_residues
MLARVWSASIVGIDAVKVGVEVDISGGLPGIVVLGLPDSAVQESKERVKATLKNAGFAFPMRKIVINLTPADLRKEGPCF
DLPISIGILAASEQVKSDLLGDYLFLGEVSLDGSLRPVAGVLPIAATAKKMGIAGLVVPVDNAQEASVVEGLEVHGCKNV
SEVVDLLNNPGKHQPVKLDESQELTPISYAIADLKDVKGQAHGRRALEIAAAGGHNLIFVGPPGSGKTMLARRLPGILPP
LSFAEALEVTRIHSVAGLLKNRGSLVRDRPFRSPHHSASGPSLVGGGGFPRPGEISLSHRGILFLDELTEFKRDVLEFLR
QPLEDGYVTISRTRQSVMFPAQFTLVASTNPCPCGYYGDTIQQCTCSPRQREQYWAKLSGPLMDRIDLQVAVNRLKPEEI
TQQPTGEESVSVRERVQKARDRAINRFKDEPNLRCNAQMQSRHLQTWCKLDDGSRSLLEAAIKKLGLSARASDRILKVAR
TIADLAGEDELKPNHVAEAIQYRTIDRMQ
>Mature_509_residues
MLARVWSASIVGIDAVKVGVEVDISGGLPGIVVLGLPDSAVQESKERVKATLKNAGFAFPMRKIVINLTPADLRKEGPCF
DLPISIGILAASEQVKSDLLGDYLFLGEVSLDGSLRPVAGVLPIAATAKKMGIAGLVVPVDNAQEASVVEGLEVHGCKNV
SEVVDLLNNPGKHQPVKLDESQELTPISYAIADLKDVKGQAHGRRALEIAAAGGHNLIFVGPPGSGKTMLARRLPGILPP
LSFAEALEVTRIHSVAGLLKNRGSLVRDRPFRSPHHSASGPSLVGGGGFPRPGEISLSHRGILFLDELTEFKRDVLEFLR
QPLEDGYVTISRTRQSVMFPAQFTLVASTNPCPCGYYGDTIQQCTCSPRQREQYWAKLSGPLMDRIDLQVAVNRLKPEEI
TQQPTGEESVSVRERVQKARDRAINRFKDEPNLRCNAQMQSRHLQTWCKLDDGSRSLLEAAIKKLGLSARASDRILKVAR
TIADLAGEDELKPNHVAEAIQYRTIDRMQ

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=513, Percent_Identity=45.0292397660819, Blast_Score=405, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 55275; Mature: 55275

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARVWSASIVGIDAVKVGVEVDISGGLPGIVVLGLPDSAVQESKERVKATLKNAGFAFP
CCCCEECCEEEEEEEEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCC
MRKIVINLTPADLRKEGPCFDLPISIGILAASEQVKSDLLGDYLFLGEVSLDGSLRPVAG
EEHEEEECCCHHHHCCCCCEECCCEEEEEECHHHHHHHHHHCEEEEEEEECCCCCCCHHH
VLPIAATAKKMGIAGLVVPVDNAQEASVVEGLEVHGCKNVSEVVDLLNNPGKHQPVKLDE
HHHHHHHHHHCCCEEEEEECCCCCHHHHHCCHHHCCCCCHHHHHHHHCCCCCCCCCCCCC
SQELTPISYAIADLKDVKGQAHGRRALEIAAAGGHNLIFVGPPGSGKTMLARRLPGILPP
CCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHCCCCCCC
LSFAEALEVTRIHSVAGLLKNRGSLVRDRPFRSPHHSASGPSLVGGGGFPRPGEISLSHR
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCEEECCC
GILFLDELTEFKRDVLEFLRQPLEDGYVTISRTRQSVMFPAQFTLVASTNPCPCGYYGDT
CEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEECCEEEEEEECCCCCCCCCCCCH
IQQCTCSPRQREQYWAKLSGPLMDRIDLQVAVNRLKPEEITQQPTGEESVSVRERVQKAR
HHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHH
DRAINRFKDEPNLRCNAQMQSRHLQTWCKLDDGSRSLLEAAIKKLGLSARASDRILKVAR
HHHHHHHCCCCCCEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
TIADLAGEDELKPNHVAEAIQYRTIDRMQ
HHHHHCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLARVWSASIVGIDAVKVGVEVDISGGLPGIVVLGLPDSAVQESKERVKATLKNAGFAFP
CCCCEECCEEEEEEEEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCC
MRKIVINLTPADLRKEGPCFDLPISIGILAASEQVKSDLLGDYLFLGEVSLDGSLRPVAG
EEHEEEECCCHHHHCCCCCEECCCEEEEEECHHHHHHHHHHCEEEEEEEECCCCCCCHHH
VLPIAATAKKMGIAGLVVPVDNAQEASVVEGLEVHGCKNVSEVVDLLNNPGKHQPVKLDE
HHHHHHHHHHCCCEEEEEECCCCCHHHHHCCHHHCCCCCHHHHHHHHCCCCCCCCCCCCC
SQELTPISYAIADLKDVKGQAHGRRALEIAAAGGHNLIFVGPPGSGKTMLARRLPGILPP
CCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHCCCCCCC
LSFAEALEVTRIHSVAGLLKNRGSLVRDRPFRSPHHSASGPSLVGGGGFPRPGEISLSHR
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCEEECCC
GILFLDELTEFKRDVLEFLRQPLEDGYVTISRTRQSVMFPAQFTLVASTNPCPCGYYGDT
CEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEECCEEEEEEECCCCCCCCCCCCH
IQQCTCSPRQREQYWAKLSGPLMDRIDLQVAVNRLKPEEITQQPTGEESVSVRERVQKAR
HHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHH
DRAINRFKDEPNLRCNAQMQSRHLQTWCKLDDGSRSLLEAAIKKLGLSARASDRILKVAR
HHHHHHHCCCCCCEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
TIADLAGEDELKPNHVAEAIQYRTIDRMQ
HHHHHCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]