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The map label for this gene is fadE25 [H]

Identifier: 17231550

GI number: 17231550

Start: 4885563

End: 4887371

Strand: Direct

Name: fadE25 [H]

Synonym: alr4058

Alternate gene names: 17231550

Gene position: 4885563-4887371 (Clockwise)

Preceding gene: 17231549

Following gene: 17231551

Centisome position: 76.17

GC content: 49.47

Gene sequence:

>1809_bases
ATGCAGCCACTCAAGCAATATTGGATCGCAGAAGCATTAGAGAAAGATTTGGGCGACCCTAGCAACCCAAATAATGTGAT
GTCGTTTAAGCAGGTAATTGACCTGGACGAACGAGAAGAGTTTCCCCATGAGATTATTAATTGGCTCTATAACTGGAAAC
TCCAGCACTATTACATCCCTACAGAATGCGGCGGTGAATTTACCTCCTTTGACGAGTTTATCGCCTTTGTGCGCGTCCTT
TCCCGCCGTGACCAAACCGCAGCGATCGCCTTCACCACCATGTTCTGGTCATACCTGACATGGATGGCAGGCACGGACGA
GCAGAAGCGCACCCTAGCCAGCTTCATGAAAGATGCCAACGGGGCTATGTGTCTGGCTTATTCAGAGAAAGCCCACGGTA
GCGATTTACTCGCCAGTGATGTGAGAGCGACAAAAGCCCCTGGTGGCTACATCCTCAACGGCGAAAAATGGCCGATTAAC
CGCGCCACCATCTCCGGGGTTACCTTCGTCCTAGCCAAAACCGACGAAGAAGGCGGAGCGCGTAGCCTCTCCCTATTCAT
GATAGAAAAGAGCAAAATCGACCCCGCCAACTATAGCCACCTACCAAAAATCTTTACCCACGGTGTGCGCGGTTCAGATA
TGAGTGGGATCAAATTTGAGAACTGCTTCATCCCCGAATCTATGCGGTTGGGGGCAGAAGGGGCAGGACTAGAACTAGCA
CTCAAAGGCTTCCAAATCACCCGCGCTTTATGTGCCGCCTTTTCCCAAGGGGCTGCTGATACTGCCCTGCGGACTACCCT
CAAGTTTGCCTTGGGGCGGCAGTTATACGGCAAGACCGTTTATGATATGCCCCAACCCAAACGCACTTTAACAGATGCGT
TTCTGGATATCCTGATTTGCGACTGCGCCACCATTGGCGTTACCCGTGGGTTTAACACCATGCCAGAGCAAATCAGCGTC
TGGTCAGCCGTGGTGAAATACTTCGTCACCACCAACCTAGAAACAGTCGTGCAGAATGTCTCCGTCGTTTTAGGTTCACG
CTTTTATATGCGTGAAGAACACGACTATGGCATTTTCCAAAAAGTACTGCGGGATAACGCCATCATCAGTATGTTTGATG
GCAGTACTGTAGTTAACCTCCATGCTTTGTTGCTGCAACTACGTCAACTCGCCAAGTCCCGCGCCAGAAATGCTGGACGC
AACCAAGAAACCTTACAAGCACGTCTAGCAGCCACCTTTGACTTAACCCAAACCTTACCCGCTTTTGATGGTAAGAAGTT
GGAACTAGTCAACCGGGGTGGTGATGACGTTTTGCAAGGATTAGGTTTAGCCCTGACATCTTTAATTGATTTAAAGGCAG
ACTCCAGCCTCAATTCCGAAGTATTGCAGCAAATTATCCAACTAACCGAAATAGTACAGGAGGAATTAAACACTCTTGAT
CATCAGATTACAGAGTCTACCTTCCAGTTTGGGCATGAGCAAGCACCAGAAGTCTTCGACATAGCCAAACAATACTGCGT
CCTGCACGCGGCTGCTAGCTCTGTCTATATGTGGCTTCACAACCGCCATCATTTGGGAGACTTCTTTAGTCATGGCGAGT
GGTTGGCACTCGGCCTCCGCAAACTACTGTTAACCTTCCGCCCAGCTAAAGCCTTACCAGGGCGCATTGATGACGCAGCA
GTTGCCCAAGAGTTAGTCCGGTTGTACACCGACAATCGGATGTTTTCCATCGTTCCCTTCCAATTAGCAAACCCTCAACT
ACAAGAGACTAAAACTGATGCAACTCAAAGACTCCAACTCCAAGCCTAG

Upstream 100 bases:

>100_bases
TGGAGCGAAAACCCCAAATACACCGCCAGCTATCGGCGACTACAAGGGGAAGTAAATTCTTTGCTGGAAAAGGTGCAAGT
TACTCACTAAGGAGAAAATT

Downstream 100 bases:

>100_bases
TACTAATAACGCCGTTGACACTATCCAAGGGTGGTTAGTTAACCAGATTGCCACACAATTAAACATCAATGCTCAAACCA
TCAAAGTTACTGAACCCTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
MQPLKQYWIAEALEKDLGDPSNPNNVMSFKQVIDLDEREEFPHEIINWLYNWKLQHYYIPTECGGEFTSFDEFIAFVRVL
SRRDQTAAIAFTTMFWSYLTWMAGTDEQKRTLASFMKDANGAMCLAYSEKAHGSDLLASDVRATKAPGGYILNGEKWPIN
RATISGVTFVLAKTDEEGGARSLSLFMIEKSKIDPANYSHLPKIFTHGVRGSDMSGIKFENCFIPESMRLGAEGAGLELA
LKGFQITRALCAAFSQGAADTALRTTLKFALGRQLYGKTVYDMPQPKRTLTDAFLDILICDCATIGVTRGFNTMPEQISV
WSAVVKYFVTTNLETVVQNVSVVLGSRFYMREEHDYGIFQKVLRDNAIISMFDGSTVVNLHALLLQLRQLAKSRARNAGR
NQETLQARLAATFDLTQTLPAFDGKKLELVNRGGDDVLQGLGLALTSLIDLKADSSLNSEVLQQIIQLTEIVQEELNTLD
HQITESTFQFGHEQAPEVFDIAKQYCVLHAAASSVYMWLHNRHHLGDFFSHGEWLALGLRKLLLTFRPAKALPGRIDDAA
VAQELVRLYTDNRMFSIVPFQLANPQLQETKTDATQRLQLQA

Sequences:

>Translated_602_residues
MQPLKQYWIAEALEKDLGDPSNPNNVMSFKQVIDLDEREEFPHEIINWLYNWKLQHYYIPTECGGEFTSFDEFIAFVRVL
SRRDQTAAIAFTTMFWSYLTWMAGTDEQKRTLASFMKDANGAMCLAYSEKAHGSDLLASDVRATKAPGGYILNGEKWPIN
RATISGVTFVLAKTDEEGGARSLSLFMIEKSKIDPANYSHLPKIFTHGVRGSDMSGIKFENCFIPESMRLGAEGAGLELA
LKGFQITRALCAAFSQGAADTALRTTLKFALGRQLYGKTVYDMPQPKRTLTDAFLDILICDCATIGVTRGFNTMPEQISV
WSAVVKYFVTTNLETVVQNVSVVLGSRFYMREEHDYGIFQKVLRDNAIISMFDGSTVVNLHALLLQLRQLAKSRARNAGR
NQETLQARLAATFDLTQTLPAFDGKKLELVNRGGDDVLQGLGLALTSLIDLKADSSLNSEVLQQIIQLTEIVQEELNTLD
HQITESTFQFGHEQAPEVFDIAKQYCVLHAAASSVYMWLHNRHHLGDFFSHGEWLALGLRKLLLTFRPAKALPGRIDDAA
VAQELVRLYTDNRMFSIVPFQLANPQLQETKTDATQRLQLQA
>Mature_602_residues
MQPLKQYWIAEALEKDLGDPSNPNNVMSFKQVIDLDEREEFPHEIINWLYNWKLQHYYIPTECGGEFTSFDEFIAFVRVL
SRRDQTAAIAFTTMFWSYLTWMAGTDEQKRTLASFMKDANGAMCLAYSEKAHGSDLLASDVRATKAPGGYILNGEKWPIN
RATISGVTFVLAKTDEEGGARSLSLFMIEKSKIDPANYSHLPKIFTHGVRGSDMSGIKFENCFIPESMRLGAEGAGLELA
LKGFQITRALCAAFSQGAADTALRTTLKFALGRQLYGKTVYDMPQPKRTLTDAFLDILICDCATIGVTRGFNTMPEQISV
WSAVVKYFVTTNLETVVQNVSVVLGSRFYMREEHDYGIFQKVLRDNAIISMFDGSTVVNLHALLLQLRQLAKSRARNAGR
NQETLQARLAATFDLTQTLPAFDGKKLELVNRGGDDVLQGLGLALTSLIDLKADSSLNSEVLQQIIQLTEIVQEELNTLD
HQITESTFQFGHEQAPEVFDIAKQYCVLHAAASSVYMWLHNRHHLGDFFSHGEWLALGLRKLLLTFRPAKALPGRIDDAA
VAQELVRLYTDNRMFSIVPFQLANPQLQETKTDATQRLQLQA

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=355, Percent_Identity=24.5070422535211, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI187960098, Length=351, Percent_Identity=23.3618233618234, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4557231, Length=352, Percent_Identity=24.1477272727273, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI226958412, Length=371, Percent_Identity=21.832884097035, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI226958414, Length=367, Percent_Identity=21.7983651226158, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI4557233, Length=251, Percent_Identity=25.0996015936255, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI21361497, Length=404, Percent_Identity=25.2475247524752, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI7656849, Length=344, Percent_Identity=21.8023255813953, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4501857, Length=265, Percent_Identity=26.7924528301887, Blast_Score=71, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17534899, Length=349, Percent_Identity=24.3553008595989, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17569725, Length=372, Percent_Identity=24.4623655913978, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538396, Length=347, Percent_Identity=23.6311239193084, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17570075, Length=373, Percent_Identity=24.1286863270777, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71982178, Length=254, Percent_Identity=25.9842519685039, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=356, Percent_Identity=21.3483146067416, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71985184, Length=359, Percent_Identity=21.1699164345404, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71990804, Length=251, Percent_Identity=23.5059760956175, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17533517, Length=360, Percent_Identity=23.8888888888889, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21356377, Length=274, Percent_Identity=25.1824817518248, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24660351, Length=374, Percent_Identity=22.7272727272727, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24666513, Length=359, Percent_Identity=22.8412256267409, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355753, Length=288, Percent_Identity=22.5694444444444, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 67501; Mature: 67501

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPLKQYWIAEALEKDLGDPSNPNNVMSFKQVIDLDEREEFPHEIINWLYNWKLQHYYIP
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHCCHHHHHHHHHCCEEEEEECC
TECGGEFTSFDEFIAFVRVLSRRDQTAAIAFTTMFWSYLTWMAGTDEQKRTLASFMKDAN
HHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
GAMCLAYSEKAHGSDLLASDVRATKAPGGYILNGEKWPINRATISGVTFVLAKTDEEGGA
CCEEEEECCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCEECCCEEEEEEECCCCCCC
RSLSLFMIEKSKIDPANYSHLPKIFTHGVRGSDMSGIKFENCFIPESMRLGAEGAGLELA
CEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCEECCCCCCHHHHCCCCCCCCEEE
LKGFQITRALCAAFSQGAADTALRTTLKFALGRQLYGKTVYDMPQPKRTLTDAFLDILIC
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
DCATIGVTRGFNTMPEQISVWSAVVKYFVTTNLETVVQNVSVVLGSRFYMREEHDYGIFQ
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHCCCCCCHHHHH
KVLRDNAIISMFDGSTVVNLHALLLQLRQLAKSRARNAGRNQETLQARLAATFDLTQTLP
HHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
AFDGKKLELVNRGGDDVLQGLGLALTSLIDLKADSSLNSEVLQQIIQLTEIVQEELNTLD
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HQITESTFQFGHEQAPEVFDIAKQYCVLHAAASSVYMWLHNRHHLGDFFSHGEWLALGLR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHH
KLLLTFRPAKALPGRIDDAAVAQELVRLYTDNRMFSIVPFQLANPQLQETKTDATQRLQL
HHHHHCCCHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECHHHCCCCHHHHHHHHHHHEEE
QA
CC
>Mature Secondary Structure
MQPLKQYWIAEALEKDLGDPSNPNNVMSFKQVIDLDEREEFPHEIINWLYNWKLQHYYIP
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHCCHHHHHHHHHCCEEEEEECC
TECGGEFTSFDEFIAFVRVLSRRDQTAAIAFTTMFWSYLTWMAGTDEQKRTLASFMKDAN
HHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
GAMCLAYSEKAHGSDLLASDVRATKAPGGYILNGEKWPINRATISGVTFVLAKTDEEGGA
CCEEEEECCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCEECCCEEEEEEECCCCCCC
RSLSLFMIEKSKIDPANYSHLPKIFTHGVRGSDMSGIKFENCFIPESMRLGAEGAGLELA
CEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCEECCCCCCHHHHCCCCCCCCEEE
LKGFQITRALCAAFSQGAADTALRTTLKFALGRQLYGKTVYDMPQPKRTLTDAFLDILIC
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
DCATIGVTRGFNTMPEQISVWSAVVKYFVTTNLETVVQNVSVVLGSRFYMREEHDYGIFQ
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHCCCCCCHHHHH
KVLRDNAIISMFDGSTVVNLHALLLQLRQLAKSRARNAGRNQETLQARLAATFDLTQTLP
HHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
AFDGKKLELVNRGGDDVLQGLGLALTSLIDLKADSSLNSEVLQQIIQLTEIVQEELNTLD
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HQITESTFQFGHEQAPEVFDIAKQYCVLHAAASSVYMWLHNRHHLGDFFSHGEWLALGLR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHH
KLLLTFRPAKALPGRIDDAAVAQELVRLYTDNRMFSIVPFQLANPQLQETKTDATQRLQL
HHHHHCCCHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECHHHCCCCHHHHHHHHHHHEEE
QA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]