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The map label for this gene is dltE [H]

Identifier: 17231503

GI number: 17231503

Start: 4831007

End: 4831777

Strand: Direct

Name: dltE [H]

Synonym: alr4011

Alternate gene names: 17231503

Gene position: 4831007-4831777 (Clockwise)

Preceding gene: 17231502

Following gene: 17231507

Centisome position: 75.32

GC content: 40.86

Gene sequence:

>771_bases
ATGGTGAAAAAAGTATTACATCCGGCTTACAACAAGAAATCTCCAATTTCAACCCAAGGCAACACAGTTTTAATCACTGG
AGGTGCATCAGGAATTGGTTTGGCACTAGCACACAAATTTCTGCAAGCGCAAAATACAGTGATAATCACTGGACGGAATG
CTGAAAAATTAGCTGGCGTAAAGGCATTATGGCCGGAAATTCTCACTGAAGTTGCTGATTTACAGGATTTAAATATCTTG
CAAAAGCTAGTCAATCGTTACCCAAATGTGAATATCCTGATCAACAATGCTGGCATTCAATATAACTACGAATTTACCAA
TCCAGAAATTACCCCAGAGTTAATCGAAGCAGAGTTACGAACTAACTTAATTGCGCCATTGCAATTGATTAAACTGATGT
TACCCCATCTGTTGAACAAGCCCGAAGCCGCGATTATAAATGTTTCCTCTGGCTTAGGATTAGTTCCCAAAGAAAGCGCA
CCTGTCTACTGTGGTAGTAAAGCAGGGATACATATTGCTACTAAAGCCTTGCGCTGGCAACTCGAAACCACATCTATTAA
AGTATTTGAAATTATCGCGCCTTTAGTTGATACACCCATGACTCAAGGACGGGGTAAAGGGAAGATTTCCCCTGATGCAC
TGGTAAATGAATTTTGGCATGATTTTACACGCGATCGCTATGAAATGCGAATCGGTAAAACCAAACTACTGTTTTTCCTC
CAGCGATGGTTTCCCCAACTAGCAGACAAAATTCTGCGCCCTGGAATTTAA

Upstream 100 bases:

>100_bases
AGGAAAAATTTCCACCCTGATTAACATAAGTTAATGACTTCACCATTGCTCCAGATTACATCTAAAGAAGATGTTCTGAA
ATGCGCTTACTAAACTGGCA

Downstream 100 bases:

>100_bases
CTTAATTGGGCGCAAGCCAGGTTTTCTCATCACTTCAATTAAACTCTTGACTCTACTATTTGCTGCGGTGCTTGTAGCGC
CTGGGGTAAACTCCAATCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MVKKVLHPAYNKKSPISTQGNTVLITGGASGIGLALAHKFLQAQNTVIITGRNAEKLAGVKALWPEILTEVADLQDLNIL
QKLVNRYPNVNILINNAGIQYNYEFTNPEITPELIEAELRTNLIAPLQLIKLMLPHLLNKPEAAIINVSSGLGLVPKESA
PVYCGSKAGIHIATKALRWQLETTSIKVFEIIAPLVDTPMTQGRGKGKISPDALVNEFWHDFTRDRYEMRIGKTKLLFFL
QRWFPQLADKILRPGI

Sequences:

>Translated_256_residues
MVKKVLHPAYNKKSPISTQGNTVLITGGASGIGLALAHKFLQAQNTVIITGRNAEKLAGVKALWPEILTEVADLQDLNIL
QKLVNRYPNVNILINNAGIQYNYEFTNPEITPELIEAELRTNLIAPLQLIKLMLPHLLNKPEAAIINVSSGLGLVPKESA
PVYCGSKAGIHIATKALRWQLETTSIKVFEIIAPLVDTPMTQGRGKGKISPDALVNEFWHDFTRDRYEMRIGKTKLLFFL
QRWFPQLADKILRPGI
>Mature_256_residues
MVKKVLHPAYNKKSPISTQGNTVLITGGASGIGLALAHKFLQAQNTVIITGRNAEKLAGVKALWPEILTEVADLQDLNIL
QKLVNRYPNVNILINNAGIQYNYEFTNPEITPELIEAELRTNLIAPLQLIKLMLPHLLNKPEAAIINVSSGLGLVPKESA
PVYCGSKAGIHIATKALRWQLETTSIKVFEIIAPLVDTPMTQGRGKGKISPDALVNEFWHDFTRDRYEMRIGKTKLLFFL
QRWFPQLADKILRPGI

Specific function: Unknown

COG id: COG3967

COG function: function code M; Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=32, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI20149619, Length=272, Percent_Identity=26.4705882352941, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI224922801, Length=166, Percent_Identity=34.3373493975904, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI7705855, Length=194, Percent_Identity=23.1958762886598, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4557649, Length=214, Percent_Identity=24.7663551401869, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI226371731, Length=196, Percent_Identity=27.0408163265306, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787820, Length=192, Percent_Identity=28.6458333333333, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17567345, Length=195, Percent_Identity=30.2564102564103, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=214, Percent_Identity=28.5046728971963, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=220, Percent_Identity=27.7272727272727, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=184, Percent_Identity=29.3478260869565, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=216, Percent_Identity=28.2407407407407, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=200, Percent_Identity=31, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI23397609, Length=180, Percent_Identity=32.7777777777778, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21358495, Length=260, Percent_Identity=26.9230769230769, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644339, Length=198, Percent_Identity=31.3131313131313, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28448; Mature: 28448

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKKVLHPAYNKKSPISTQGNTVLITGGASGIGLALAHKFLQAQNTVIITGRNAEKLAGV
CCCHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHH
KALWPEILTEVADLQDLNILQKLVNRYPNVNILINNAGIQYNYEFTNPEITPELIEAELR
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCCHHHHHHHHH
TNLIAPLQLIKLMLPHLLNKPEAAIINVSSGLGLVPKESAPVYCGSKAGIHIATKALRWQ
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEECCCCCEEEEEHHHEEE
LETTSIKVFEIIAPLVDTPMTQGRGKGKISPDALVNEFWHDFTRDRYEMRIGKTKLLFFL
EECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
QRWFPQLADKILRPGI
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVKKVLHPAYNKKSPISTQGNTVLITGGASGIGLALAHKFLQAQNTVIITGRNAEKLAGV
CCCHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHH
KALWPEILTEVADLQDLNILQKLVNRYPNVNILINNAGIQYNYEFTNPEITPELIEAELR
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCCHHHHHHHHH
TNLIAPLQLIKLMLPHLLNKPEAAIINVSSGLGLVPKESAPVYCGSKAGIHIATKALRWQ
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEECCCCCEEEEEHHHEEE
LETTSIKVFEIIAPLVDTPMTQGRGKGKISPDALVNEFWHDFTRDRYEMRIGKTKLLFFL
EECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
QRWFPQLADKILRPGI
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 7797557 [H]