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The map label for this gene is ftsZ

Identifier: 17231350

GI number: 17231350

Start: 4655902

End: 4657188

Strand: Direct

Name: ftsZ

Synonym: alr3858

Alternate gene names: 17231350

Gene position: 4655902-4657188 (Clockwise)

Preceding gene: 17231349

Following gene: 17231355

Centisome position: 72.59

GC content: 44.68

Gene sequence:

>1287_bases
ATGACACTTGATAATAACCAAGAGCTTACCTATAGAAATTCCCAATCGTTGGGACAGCCAGGTTTCTCACTGGCAGTTAA
CTCAAGCAACCCTTTCAATCACTCTGGGCTGAATTTTGGACAAAATAACGACAGTAAGAAGATTTCTGTGGAAAATAACC
GTATTGGCGAGATTGTTCCTGGGCGCGTTGCCAATATCAAAGTAATTGGTGTTGGCGGTGGTGGTGGTAATGCTGTTAAC
CGCATGATTGAATCTGATGTCTCTGGTGTAGAGTTTTGGTCAATTAATACTGATGCTCAAGCTTTGACCTTGGCAGGCGC
TCCTAGTCGTTTACAAATCGGGCAGAAACTCACGAGGGGTTTAGGTGCAGGTGGTAATCCTGCAATTGGTCAAAAAGCAG
CTGAAGAATCACGCGATGAAATTGCTACAGCCTTAGAAGGTGCTGATTTAGTATTTATCACTGCTGGGATGGGAGGTGGT
ACTGGTACTGGTGCTGCACCAATTGTTGCGGAAGTGGCAAAGGAAATGGGCGCTCTTACTGTTGGAGTGGTAACACGTCC
TTTTGTTTTTGAAGGTCGTCGCCGGACTAGTCAGGCAGAACAAGGAATTGAAGGGCTAAAAAGTAGAGTTGATACTTTAA
TTATTATTCCTAACAATAAATTATTGGAAGTGATTCCAGAACAAACACCAGTCCAAGAAGCGTTTCGTTATGCAGATGAC
GTACTACGTCAAGGGGTACAAGGCATTTCCGACATCATTACTATTCCTGGTTTGGTAAATGTAGACTTTGCTGACGTGCG
GGCTGTCATGGCCGATGCGGGATCAGCATTGATGGGTATTGGTGTGAGTTCAGGAAAATCTAGAGCCAGAGAAGCTGCGA
TCGCCGCTATATCTTCACCACTGCTAGAATGTTCTATCGAAGGTGCTAGAGGTGTTGTTTTTAACATCACTGGTGGTAGT
GACCTCACTCTACATGAAGTAAATGCTGCCGCCGAAACGATTTATGAAGTAGTTGATCCCAACGCCAACATTATTTTTGG
TGCCGTGATTGATGATAGGTTGCAAGGAGAGGTGCGAATTACCGTCATTGCTACTGGATTTACTGGGGAAATACAAGCTG
CTCCCCAACAAAACGCTGCTAATGCAAGAGTTGTATCTGCTCCCCCAAAACGGACACCCACACAAACACCACTAACTAAT
TCTCCTGCACCTACTCCTGAACCAAAAGAGAAATCTGGATTGGATATCCCTGATTTTCTTCAGAGACGGCGACCACCCAA
AAATTAA

Upstream 100 bases:

>100_bases
ATCAAGAAGAGTGCCAAAATTTTTAGTGCTGTCAAACTTAATAGTTGACTCCTAGATGTGTAACACCTAAAAAAGTCGTT
TATCTACCTTCCCGAATCCA

Downstream 100 bases:

>100_bases
GCGGTTTTAGATTTGAGATTATTTAAAATTTGTAGTCTCTAGTCAGGCTAAATGCTGTATAAAAACTGCTAATTTTCAAG
TTCAGAGGTATGTTTTTTAC

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTLDNNQELTYRNSQSLGQPGFSLAVNSSNPFNHSGLNFGQNNDSKKISVENNRIGEIVPGRVANIKVIGVGGGGGNAVN
RMIESDVSGVEFWSINTDAQALTLAGAPSRLQIGQKLTRGLGAGGNPAIGQKAAEESRDEIATALEGADLVFITAGMGGG
TGTGAAPIVAEVAKEMGALTVGVVTRPFVFEGRRRTSQAEQGIEGLKSRVDTLIIIPNNKLLEVIPEQTPVQEAFRYADD
VLRQGVQGISDIITIPGLVNVDFADVRAVMADAGSALMGIGVSSGKSRAREAAIAAISSPLLECSIEGARGVVFNITGGS
DLTLHEVNAAAETIYEVVDPNANIIFGAVIDDRLQGEVRITVIATGFTGEIQAAPQQNAANARVVSAPPKRTPTQTPLTN
SPAPTPEPKEKSGLDIPDFLQRRRPPKN

Sequences:

>Translated_428_residues
MTLDNNQELTYRNSQSLGQPGFSLAVNSSNPFNHSGLNFGQNNDSKKISVENNRIGEIVPGRVANIKVIGVGGGGGNAVN
RMIESDVSGVEFWSINTDAQALTLAGAPSRLQIGQKLTRGLGAGGNPAIGQKAAEESRDEIATALEGADLVFITAGMGGG
TGTGAAPIVAEVAKEMGALTVGVVTRPFVFEGRRRTSQAEQGIEGLKSRVDTLIIIPNNKLLEVIPEQTPVQEAFRYADD
VLRQGVQGISDIITIPGLVNVDFADVRAVMADAGSALMGIGVSSGKSRAREAAIAAISSPLLECSIEGARGVVFNITGGS
DLTLHEVNAAAETIYEVVDPNANIIFGAVIDDRLQGEVRITVIATGFTGEIQAAPQQNAANARVVSAPPKRTPTQTPLTN
SPAPTPEPKEKSGLDIPDFLQRRRPPKN
>Mature_427_residues
TLDNNQELTYRNSQSLGQPGFSLAVNSSNPFNHSGLNFGQNNDSKKISVENNRIGEIVPGRVANIKVIGVGGGGGNAVNR
MIESDVSGVEFWSINTDAQALTLAGAPSRLQIGQKLTRGLGAGGNPAIGQKAAEESRDEIATALEGADLVFITAGMGGGT
GTGAAPIVAEVAKEMGALTVGVVTRPFVFEGRRRTSQAEQGIEGLKSRVDTLIIIPNNKLLEVIPEQTPVQEAFRYADDV
LRQGVQGISDIITIPGLVNVDFADVRAVMADAGSALMGIGVSSGKSRAREAAIAAISSPLLECSIEGARGVVFNITGGSD
LTLHEVNAAAETIYEVVDPNANIIFGAVIDDRLQGEVRITVIATGFTGEIQAAPQQNAANARVVSAPPKRTPTQTPLTNS
PAPTPEPKEKSGLDIPDFLQRRRPPKN

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family

Homologues:

Organism=Escherichia coli, GI1786284, Length=360, Percent_Identity=49.4444444444444, Blast_Score=292, Evalue=2e-80,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): FTSZ_NOSS1 (P45482)

Other databases:

- EMBL:   Z31371
- EMBL:   BA000019
- EMBL:   U14408
- PIR:   AC2288
- PIR:   JC4289
- RefSeq:   NP_487898.1
- ProteinModelPortal:   P45482
- SMR:   P45482
- STRING:   P45482
- GeneID:   1107456
- GenomeReviews:   BA000019_GR
- KEGG:   ana:alr3858
- NMPDR:   fig|103690.1.peg.4165
- eggNOG:   COG0206
- HOGENOM:   HBG478075
- OMA:   VNIVPEL
- PhylomeDB:   P45482
- ProtClustDB:   PRK09330
- BioCyc:   NSP103690:ALR3858-MONOMER
- GO:   GO:0005737
- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008
- Gene3D:   G3DSA:3.30.1330.20
- Gene3D:   G3DSA:3.40.50.1440
- PRINTS:   PR00423
- SMART:   SM00864
- SMART:   SM00865
- TIGRFAMs:   TIGR00065

Pfam domain/function: PF00091 Tubulin; SSF55307 Tub_FtsZ_C; SSF52490 Tubulin_FtsZ

EC number: NA

Molecular weight: Translated: 44731; Mature: 44600

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS01134 FTSZ_1; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDNNQELTYRNSQSLGQPGFSLAVNSSNPFNHSGLNFGQNNDSKKISVENNRIGEIVP
CCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
GRVANIKVIGVGGGGGNAVNRMIESDVSGVEFWSINTDAQALTLAGAPSRLQIGQKLTRG
CCEEEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHH
LGAGGNPAIGQKAAEESRDEIATALEGADLVFITAGMGGGTGTGAAPIVAEVAKEMGALT
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCEE
VGVVTRPFVFEGRRRTSQAEQGIEGLKSRVDTLIIIPNNKLLEVIPEQTPVQEAFRYADD
EEEECCCCEECCCHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCCHHHHHHHHHH
VLRQGVQGISDIITIPGLVNVDFADVRAVMADAGSALMGIGVSSGKSRAREAAIAAISSP
HHHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCC
LLECSIEGARGVVFNITGGSDLTLHEVNAAAETIYEVVDPNANIIFGAVIDDRLQGEVRI
HHEEECCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEE
TVIATGFTGEIQAAPQQNAANARVVSAPPKRTPTQTPLTNSPAPTPEPKEKSGLDIPDFL
EEEEECCCCCEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
QRRRPPKN
HHCCCCCC
>Mature Secondary Structure 
TLDNNQELTYRNSQSLGQPGFSLAVNSSNPFNHSGLNFGQNNDSKKISVENNRIGEIVP
CCCCCCCEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
GRVANIKVIGVGGGGGNAVNRMIESDVSGVEFWSINTDAQALTLAGAPSRLQIGQKLTRG
CCEEEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHH
LGAGGNPAIGQKAAEESRDEIATALEGADLVFITAGMGGGTGTGAAPIVAEVAKEMGALT
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCEE
VGVVTRPFVFEGRRRTSQAEQGIEGLKSRVDTLIIIPNNKLLEVIPEQTPVQEAFRYADD
EEEECCCCEECCCHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCCHHHHHHHHHH
VLRQGVQGISDIITIPGLVNVDFADVRAVMADAGSALMGIGVSSGKSRAREAAIAAISSP
HHHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCC
LLECSIEGARGVVFNITGGSDLTLHEVNAAAETIYEVVDPNANIIFGAVIDDRLQGEVRI
HHEEECCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEE
TVIATGFTGEIQAAPQQNAANARVVSAPPKRTPTQTPLTNSPAPTPEPKEKSGLDIPDFL
EEEEECCCCCEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
QRRRPPKN
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8525061; 11759840; 7557485