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The map label for this gene is ndhK [H]

Identifier: 17231333

GI number: 17231333

Start: 4641116

End: 4641853

Strand: Reverse

Name: ndhK [H]

Synonym: all3841

Alternate gene names: 17231333

Gene position: 4641853-4641116 (Counterclockwise)

Preceding gene: 17231334

Following gene: 17231332

Centisome position: 72.37

GC content: 46.75

Gene sequence:

>738_bases
ATGGTCTTGAATTCTGATTTAACTACTCAGGACAAAGAGCGAATCATCAACCCCATTGAACGTCCTACAATCACTCAAGA
CCTGTCGGAAAATGTGATTTTAACTACGGTTGATGACCTCTATAACTGGGCTAGGCTTTCGAGCCTGTGGCCGTTGTTGT
TTGGTACAGCTTGCTGCTTTATTGAGTTTGCAGCATTAATTGGTTCGCGTTTTGACTTTGACCGCTTCGGGTTAATTCCC
CGTTCCAGTCCCCGTCAAGCCGATTTGATTATCACAGCTGGGACAATCACCATGAAGATGGCTCCTCAATTGGTGCGTCT
TTATGAACAAATGCCCGAACCTAAGTATGTAATTGCGATGGGTGCTTGCACAATTACAGGCGGTATGTTTAGCGTTGATT
CGCCTACGGCTGTGCGGGGAGTTGATAAGTTAATTCCCGTGGATGTCTACTTACCTGGTTGTCCTCCCCGTCCGGAAGCA
ATTATCGACGCAATTATTAAGCTGCGGAAGAAGATTGCTAACGACTCTATGCAGGAACGGAGTCTGATTCGGCAAACCCA
TCGTTTCTACAGCACGACTCATAACTTGAAGCCAGTACCAGACATCTTAACTGGTAAGTATATGCAGTCAGAGACTCGCT
TCAACCCACCAAAAGAGTTGACAGAAGCGATCGGTCTTCCTGTTCCCCCAGCACTGCTGACATCACAAACCCAGAAGGAG
GAACAAAAACGTGGCTGA

Upstream 100 bases:

>100_bases
CTTTTCACCGTCTGGGGCTATTGGCATTCATTGAAGCGCTAATTTTTATTGCAATTCTTGTAGTCGCCCTAGTTTACGCA
TGGCGTAAAGGAGCATTGGA

Downstream 100 bases:

>100_bases
TGAAGAATTACAACCAGTACCCGCAGCAGAAGCCGCTATAGTTCCATCTGGGCCGACTTCCCAGTGGCTAACGGAAAATG
GCTTTGCTCATGAATCTTTG

Product: NADH dehydrogenase subunit B

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I subunit K; NDH-1 subunit K; NDH-K [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MVLNSDLTTQDKERIINPIERPTITQDLSENVILTTVDDLYNWARLSSLWPLLFGTACCFIEFAALIGSRFDFDRFGLIP
RSSPRQADLIITAGTITMKMAPQLVRLYEQMPEPKYVIAMGACTITGGMFSVDSPTAVRGVDKLIPVDVYLPGCPPRPEA
IIDAIIKLRKKIANDSMQERSLIRQTHRFYSTTHNLKPVPDILTGKYMQSETRFNPPKELTEAIGLPVPPALLTSQTQKE
EQKRG

Sequences:

>Translated_245_residues
MVLNSDLTTQDKERIINPIERPTITQDLSENVILTTVDDLYNWARLSSLWPLLFGTACCFIEFAALIGSRFDFDRFGLIP
RSSPRQADLIITAGTITMKMAPQLVRLYEQMPEPKYVIAMGACTITGGMFSVDSPTAVRGVDKLIPVDVYLPGCPPRPEA
IIDAIIKLRKKIANDSMQERSLIRQTHRFYSTTHNLKPVPDILTGKYMQSETRFNPPKELTEAIGLPVPPALLTSQTQKE
EQKRG
>Mature_245_residues
MVLNSDLTTQDKERIINPIERPTITQDLSENVILTTVDDLYNWARLSSLWPLLFGTACCFIEFAALIGSRFDFDRFGLIP
RSSPRQADLIITAGTITMKMAPQLVRLYEQMPEPKYVIAMGACTITGGMFSVDSPTAVRGVDKLIPVDVYLPGCPPRPEA
IIDAIIKLRKKIANDSMQERSLIRQTHRFYSTTHNLKPVPDILTGKYMQSETRFNPPKELTEAIGLPVPPALLTSQTQKE
EQKRG

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG0377

COG function: function code C; NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 20 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI187281616, Length=143, Percent_Identity=51.0489510489511, Blast_Score=175, Evalue=4e-44,
Organism=Escherichia coli, GI1788624, Length=173, Percent_Identity=46.242774566474, Blast_Score=170, Evalue=7e-44,
Organism=Escherichia coli, GI1788834, Length=111, Percent_Identity=40.5405405405405, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789074, Length=108, Percent_Identity=41.6666666666667, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17509685, Length=139, Percent_Identity=51.0791366906475, Blast_Score=163, Evalue=9e-41,
Organism=Drosophila melanogaster, GI18859983, Length=139, Percent_Identity=52.5179856115108, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24642371, Length=139, Percent_Identity=52.5179856115108, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24651058, Length=136, Percent_Identity=52.2058823529412, Blast_Score=168, Evalue=3e-42,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006137
- InterPro:   IPR006138
- InterPro:   IPR014406 [H]

Pfam domain/function: PF01058 Oxidored_q6 [H]

EC number: 1.6.5.3

Molecular weight: Translated: 27493; Mature: 27493

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS01150 COMPLEX1_20K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLNSDLTTQDKERIINPIERPTITQDLSENVILTTVDDLYNWARLSSLWPLLFGTACCF
CEECCCCCCCHHHHHHCCCCCCCCHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
IEFAALIGSRFDFDRFGLIPRSSPRQADLIITAGTITMKMAPQLVRLYEQMPEPKYVIAM
HHHHHHHCCCCCHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEE
GACTITGGMFSVDSPTAVRGVDKLIPVDVYLPGCPPRPEAIIDAIIKLRKKIANDSMQER
CCHHHCCCEEECCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHH
SLIRQTHRFYSTTHNLKPVPDILTGKYMQSETRFNPPKELTEAIGLPVPPALLTSQTQKE
HHHHHHHHHHHHCCCCCCCCHHHHCHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHH
EQKRG
HHHCC
>Mature Secondary Structure
MVLNSDLTTQDKERIINPIERPTITQDLSENVILTTVDDLYNWARLSSLWPLLFGTACCF
CEECCCCCCCHHHHHHCCCCCCCCHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
IEFAALIGSRFDFDRFGLIPRSSPRQADLIITAGTITMKMAPQLVRLYEQMPEPKYVIAM
HHHHHHHCCCCCHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEE
GACTITGGMFSVDSPTAVRGVDKLIPVDVYLPGCPPRPEAIIDAIIKLRKKIANDSMQER
CCHHHCCCEEECCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHH
SLIRQTHRFYSTTHNLKPVPDILTGKYMQSETRFNPPKELTEAIGLPVPPALLTSQTQKE
HHHHHHHHHHHHCCCCCCCCHHHHCHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHH
EQKRG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA