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The map label for this gene is clpX [H]

Identifier: 17231176

GI number: 17231176

Start: 4443983

End: 4445320

Strand: Direct

Name: clpX [H]

Synonym: alr3684

Alternate gene names: 17231176

Gene position: 4443983-4445320 (Clockwise)

Preceding gene: 17231175

Following gene: 17231177

Centisome position: 69.29

GC content: 46.41

Gene sequence:

>1338_bases
ATGTCTAAGTACGACTCCCATTTAAAATGTTCTTTCTGTGGCAAGTCTCAAGAGCAGGTGCGGAAATTGATCGCAGGGCC
GGGAGTCTACATCTGCGATGAATGTGTAGACTTGTGTAATGAAATACTAGATGAGGAGTTGCTAGATACTAGCGGTGCGG
CGGCGCAACCAGCACCAAAATCAGAACCCCCTCAAAAACGCCGCGCCCGTTCTTCTAATCTCTCCCTGAGCCAAATACCC
AAGCCTAGAGAGATTAAAAAGTACCTAGACGAACACGTTATCGGCCAAGATGAAGCAAAGAAAGTTTTATCTGTAGCCGT
TTACAACCACTACAAACGGTTGGCAATCTTGCAGTCTAAAGGTAGCGGTAAAAATGGAGATGATGCAGTAGAACTGCAAA
AATCTAATATTCTTTTAATTGGCCCTACTGGTTGTGGCAAAACTCTCCTAGCCCAAACCCTAGCCAAAATTCTCGATGTC
CCCTTTGCTGTGGCTGATGCGACAACACTCACAGAAGCAGGGTATGTAGGGGAAGACGTAGAAAATATCTTACTGCGATT
ATTACAAGTAGCTGATTTGGATGTAGAAGAAGCCCAGCGCGGCATCATCTACATTGATGAAATTGACAAAATTGCCCGCA
AGAGTGAAAACCCCTCCATCACTAGGGACGTTTCTGGTGAAGGTGTACAGCAAGCTTTGTTAAAAATGCTGGAAGGCACA
GTTGCCAACGTCCCACCCCAAGGAGGACGGAAACACCCTTACCAAGATTGCATCCAAATTGATACCAGCAATATTTTATT
TATCTGTGGCGGAGCCTTTGTTGGTTTAGAGAAGGTTGTAGACCAGAGAGGGGGCAAAAAGTCAATAGGCTTTGTGCAAC
CTGGAGAAGGGCAATCTAAAGAAAAACGGGCAGCAGATGTGTTGCGCCATCTGGAACCAGATGACTTGGTGAAATTCGGC
ATGATTCCCGAATTTATCGGTCGGGTACCAATGGTAGCCGTAGTAGATCCTCTAGATGAAGAAGCCTTGATGGCGATTCT
GACTCAACCACGTAGCGCCCTAGTTAAGCAGTACCAAAAACTGCTGAAGATGGACAATGTCCAATTAGACTTTAAACCAG
ATGCACTCAAGGCGATCGCTCAAGAAGCCTACCGCCGGAAAACTGGCGCGAGGGCATTACGGGGCATTGTGGAAGAACTT
ATGCTAGATGTGATGTACGAGTTACCATCCCGTAAAGATGTGACGCGATGCACAGTCACCAGGGAAATGGTAGAGAAGCG
ATCAACCGCAGAATTGCTAGTTCATCCGTCTTCATTGCCTAAACCGGAATCAGCTTAG

Upstream 100 bases:

>100_bases
AGAAGAAGCAAAAAATTACGGTTTGATCGATCAAGTCATCTCCAGACAAAATCTTCCCACAGCAGGGGAAAACGTCACCA
TCGTGAAATAAGAGGCTGGT

Downstream 100 bases:

>100_bases
TAGTCATGAGTCAATGGTCATTAGTTAATAGACTGTTGACTGTTGACTGTTGACTGTTGACTGTTGACTTTGGACTATTG
ACTATTGACTTTGAGCAAAT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVDLCNEILDEELLDTSGAAAQPAPKSEPPQKRRARSSNLSLSQIP
KPREIKKYLDEHVIGQDEAKKVLSVAVYNHYKRLAILQSKGSGKNGDDAVELQKSNILLIGPTGCGKTLLAQTLAKILDV
PFAVADATTLTEAGYVGEDVENILLRLLQVADLDVEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGT
VANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLEKVVDQRGGKKSIGFVQPGEGQSKEKRAADVLRHLEPDDLVKFG
MIPEFIGRVPMVAVVDPLDEEALMAILTQPRSALVKQYQKLLKMDNVQLDFKPDALKAIAQEAYRRKTGARALRGIVEEL
MLDVMYELPSRKDVTRCTVTREMVEKRSTAELLVHPSSLPKPESA

Sequences:

>Translated_445_residues
MSKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVDLCNEILDEELLDTSGAAAQPAPKSEPPQKRRARSSNLSLSQIP
KPREIKKYLDEHVIGQDEAKKVLSVAVYNHYKRLAILQSKGSGKNGDDAVELQKSNILLIGPTGCGKTLLAQTLAKILDV
PFAVADATTLTEAGYVGEDVENILLRLLQVADLDVEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGT
VANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLEKVVDQRGGKKSIGFVQPGEGQSKEKRAADVLRHLEPDDLVKFG
MIPEFIGRVPMVAVVDPLDEEALMAILTQPRSALVKQYQKLLKMDNVQLDFKPDALKAIAQEAYRRKTGARALRGIVEEL
MLDVMYELPSRKDVTRCTVTREMVEKRSTAELLVHPSSLPKPESA
>Mature_444_residues
SKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVDLCNEILDEELLDTSGAAAQPAPKSEPPQKRRARSSNLSLSQIPK
PREIKKYLDEHVIGQDEAKKVLSVAVYNHYKRLAILQSKGSGKNGDDAVELQKSNILLIGPTGCGKTLLAQTLAKILDVP
FAVADATTLTEAGYVGEDVENILLRLLQVADLDVEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGTV
ANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLEKVVDQRGGKKSIGFVQPGEGQSKEKRAADVLRHLEPDDLVKFGM
IPEFIGRVPMVAVVDPLDEEALMAILTQPRSALVKQYQKLLKMDNVQLDFKPDALKAIAQEAYRRKTGARALRGIVEELM
LDVMYELPSRKDVTRCTVTREMVEKRSTAELLVHPSSLPKPESA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=509, Percent_Identity=39.0962671905697, Blast_Score=325, Evalue=4e-89,
Organism=Escherichia coli, GI1786642, Length=440, Percent_Identity=58.8636363636364, Blast_Score=503, Evalue=1e-144,
Organism=Escherichia coli, GI1790366, Length=110, Percent_Identity=42.7272727272727, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=308, Percent_Identity=45.1298701298701, Blast_Score=268, Evalue=4e-72,
Organism=Caenorhabditis elegans, GI71982905, Length=308, Percent_Identity=45.1298701298701, Blast_Score=267, Evalue=9e-72,
Organism=Caenorhabditis elegans, GI71988663, Length=394, Percent_Identity=39.8477157360406, Blast_Score=259, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI71988660, Length=255, Percent_Identity=40.3921568627451, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=412, Percent_Identity=40.7766990291262, Blast_Score=279, Evalue=8e-76,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=48.1132075471698, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=48.1132075471698, Blast_Score=290, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 48940; Mature: 48809

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVDLCNEILDEELLDTSGAAAQPAPK
CCCCCCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SEPPQKRRARSSNLSLSQIPKPREIKKYLDEHVIGQDEAKKVLSVAVYNHYKRLAILQSK
CCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEECC
GSGKNGDDAVELQKSNILLIGPTGCGKTLLAQTLAKILDVPFAVADATTLTEAGYVGEDV
CCCCCCCCHHEEECCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHH
ENILLRLLQVADLDVEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGT
HHHHHHHHHHHCCCHHHHHCCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCH
VANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLEKVVDQRGGKKSIGFVQPGEGQSK
HCCCCCCCCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
EKRAADVLRHLEPDDLVKFGMIPEFIGRVPMVAVVDPLDEEALMAILTQPRSALVKQYQK
HHHHHHHHHHCCHHHHHHHCCCHHHHCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHH
LLKMDNVQLDFKPDALKAIAQEAYRRKTGARALRGIVEELMLDVMYELPSRKDVTRCTVT
HHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
REMVEKRSTAELLVHPSSLPKPESA
HHHHHCCCCHHEEECCCCCCCCCCC
>Mature Secondary Structure 
SKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVDLCNEILDEELLDTSGAAAQPAPK
CCCCCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SEPPQKRRARSSNLSLSQIPKPREIKKYLDEHVIGQDEAKKVLSVAVYNHYKRLAILQSK
CCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEECC
GSGKNGDDAVELQKSNILLIGPTGCGKTLLAQTLAKILDVPFAVADATTLTEAGYVGEDV
CCCCCCCCHHEEECCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHH
ENILLRLLQVADLDVEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGT
HHHHHHHHHHHCCCHHHHHCCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCH
VANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLEKVVDQRGGKKSIGFVQPGEGQSK
HCCCCCCCCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
EKRAADVLRHLEPDDLVKFGMIPEFIGRVPMVAVVDPLDEEALMAILTQPRSALVKQYQK
HHHHHHHHHHCCHHHHHHHCCCHHHHCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHH
LLKMDNVQLDFKPDALKAIAQEAYRRKTGARALRGIVEELMLDVMYELPSRKDVTRCTVT
HHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
REMVEKRSTAELLVHPSSLPKPESA
HHHHHCCCCHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA