Click here to switch to the map view.

The map label for this gene is avaIR

Identifier: 17231123

GI number: 17231123

Start: 4381849

End: 4382796

Strand: Reverse

Name: avaIR

Synonym: all3631

Alternate gene names: 17231123

Gene position: 4382796-4381849 (Counterclockwise)

Preceding gene: 17231124

Following gene: 17231122

Centisome position: 68.33

GC content: 38.29

Gene sequence:

>948_bases
GTGCCATATCAATATCATATTCAAAGCAATGATGATCTTGTGACTCCATATCAAGAAGTCCGAGCAGGATTTGTTGCTTT
AGCTTTAGAAAGAAATCGAAAAGCAACACCATTTGTTGAGCAGGCAAGAGCATTAAAGATCCGAGTAAGCCAAATTGAAA
GGCCTCAAGACCTTTTACAAATGAGGGATATTAGACCTACTCTACTAGCTGCCTCTGGGGTATCAGATAAAGCTGCTGGA
CACCTTCAAGAACAAGATAAAGTCGATGCAATAGAAGGTTTAATTCAAAACTTCCTAGAGCCTGCTGGAGAAAACTTTGT
AGAAGAACTAGTTTACCGTTTCCTGCTTACGCGTGGAGATACACTTGGTGGATCAATGCGAAATGTTGGTGGTATCCTTG
CTGAACGTAAATTTGCAAGATATATTATTTCTGCACTAACTTTATCGAATACCTCTTATAAATGGCTAGATAAAAACAGC
AAAACTTGGCTTAATCAACCTGATGATGATACAGACATTGAATTACGTCTTAGGGGATTAAGTTGGAACTTGGAGGGTAG
GAATAGGACTTTCATTTATAATGTAAATGTTCCGATTGTGCGAAAAAACATTGATATTTGTTTGTTTGATTGCAGACAAA
ATGAAATTGAAAAGAATATAATTTCAAACCCAAATATCTACATAGCTCTAGGTGAATTAAAGGGCGGTATTGACCCAGCA
GGAGCAGACGAACATTGGAAAACAGCGAACAGTGCTTTAGCCAGAATCAGAACAGCATTTGATCGGCACAGTCTTAAGCC
ATATACTTTTTTTGTGGGATCTGCTATAGAAAAAAGCATGGCAGAAGAAATTTGGCATCAACTAAATTCTGGCATTCTTA
CTAATGCAGCAAACCTCACTCAGCCTGACCAAGTTGCCTCTTTGTGCGCTTGGTTTATTCAACTTTGA

Upstream 100 bases:

>100_bases
TTCTTGTCTTACCTACTGGCAAAGGTAACAGTAGCCAACAAATGGGGACACATGGAAGAAAGACACTTCGCAAATGTGTG
TATGTTTGGAGAAAACCCTA

Downstream 100 bases:

>100_bases
TGTACAGTGACTAATTATTTGTCACTGTACACAAGATGTACAGTGACTAATTATTTGTCACTGTACACAAGATGTACAGT
GACTAATTGTTTGTCGTCGT

Product: type II site-specific deoxyribonuclease

Products: NA

Alternate protein names: R.AvaI; Endonuclease AvaI; Type II restriction enzyme AvaI

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MPYQYHIQSNDDLVTPYQEVRAGFVALALERNRKATPFVEQARALKIRVSQIERPQDLLQMRDIRPTLLAASGVSDKAAG
HLQEQDKVDAIEGLIQNFLEPAGENFVEELVYRFLLTRGDTLGGSMRNVGGILAERKFARYIISALTLSNTSYKWLDKNS
KTWLNQPDDDTDIELRLRGLSWNLEGRNRTFIYNVNVPIVRKNIDICLFDCRQNEIEKNIISNPNIYIALGELKGGIDPA
GADEHWKTANSALARIRTAFDRHSLKPYTFFVGSAIEKSMAEEIWHQLNSGILTNAANLTQPDQVASLCAWFIQL

Sequences:

>Translated_315_residues
MPYQYHIQSNDDLVTPYQEVRAGFVALALERNRKATPFVEQARALKIRVSQIERPQDLLQMRDIRPTLLAASGVSDKAAG
HLQEQDKVDAIEGLIQNFLEPAGENFVEELVYRFLLTRGDTLGGSMRNVGGILAERKFARYIISALTLSNTSYKWLDKNS
KTWLNQPDDDTDIELRLRGLSWNLEGRNRTFIYNVNVPIVRKNIDICLFDCRQNEIEKNIISNPNIYIALGELKGGIDPA
GADEHWKTANSALARIRTAFDRHSLKPYTFFVGSAIEKSMAEEIWHQLNSGILTNAANLTQPDQVASLCAWFIQL
>Mature_314_residues
PYQYHIQSNDDLVTPYQEVRAGFVALALERNRKATPFVEQARALKIRVSQIERPQDLLQMRDIRPTLLAASGVSDKAAGH
LQEQDKVDAIEGLIQNFLEPAGENFVEELVYRFLLTRGDTLGGSMRNVGGILAERKFARYIISALTLSNTSYKWLDKNSK
TWLNQPDDDTDIELRLRGLSWNLEGRNRTFIYNVNVPIVRKNIDICLFDCRQNEIEKNIISNPNIYIALGELKGGIDPAG
ADEHWKTANSALARIRTAFDRHSLKPYTFFVGSAIEKSMAEEIWHQLNSGILTNAANLTQPDQVASLCAWFIQL

Specific function: Recognizes the double-stranded sequence CYCGRG and cleaves after C-1

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): T2A1_ANAVA (P0A458)

Other databases:

- EMBL:   X98339
- PIR:   S72472
- ProteinModelPortal:   P0A458
- SMR:   P0A458
- REBASE:   165
- BRENDA:   3.1.21.4
- InterPro:   IPR011335
- InterPro:   IPR015277
- InterPro:   IPR011544
- Gene3D:   G3DSA:3.40.91.10
- ProDom:   PD040871

Pfam domain/function: PF09194 Endonuc-BsobI; SSF52980 Restrict_endonuc_II-like_core

EC number: =3.1.21.4

Molecular weight: Translated: 35679; Mature: 35548

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYQYHIQSNDDLVTPYQEVRAGFVALALERNRKATPFVEQARALKIRVSQIERPQDLLQ
CCEEEEECCCCCCCCCHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
MRDIRPTLLAASGVSDKAAGHLQEQDKVDAIEGLIQNFLEPAGENFVEELVYRFLLTRGD
HHCCCHHHEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
TLGGSMRNVGGILAERKFARYIISALTLSNTSYKWLDKNSKTWLNQPDDDTDIELRLRGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEE
SWNLEGRNRTFIYNVNVPIVRKNIDICLFDCRQNEIEKNIISNPNIYIALGELKGGIDPA
EEEECCCCEEEEEECCCEEEECCCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCCC
GADEHWKTANSALARIRTAFDRHSLKPYTFFVGSAIEKSMAEEIWHQLNSGILTNAANLT
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEECCCCCC
QPDQVASLCAWFIQL
CHHHHHHHHHHHHCC
>Mature Secondary Structure 
PYQYHIQSNDDLVTPYQEVRAGFVALALERNRKATPFVEQARALKIRVSQIERPQDLLQ
CEEEEECCCCCCCCCHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
MRDIRPTLLAASGVSDKAAGHLQEQDKVDAIEGLIQNFLEPAGENFVEELVYRFLLTRGD
HHCCCHHHEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
TLGGSMRNVGGILAERKFARYIISALTLSNTSYKWLDKNSKTWLNQPDDDTDIELRLRGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEE
SWNLEGRNRTFIYNVNVPIVRKNIDICLFDCRQNEIEKNIISNPNIYIALGELKGGIDPA
EEEECCCCEEEEEECCCEEEECCCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCCC
GADEHWKTANSALARIRTAFDRHSLKPYTFFVGSAIEKSMAEEIWHQLNSGILTNAANLT
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEECCCCCC
QPDQVASLCAWFIQL
CHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8917312