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The map label for this gene is mtnA [H]

Identifier: 17231058

GI number: 17231058

Start: 4307340

End: 4308383

Strand: Reverse

Name: mtnA [H]

Synonym: all3566

Alternate gene names: 17231058

Gene position: 4308383-4307340 (Counterclockwise)

Preceding gene: 17231059

Following gene: 17231056

Centisome position: 67.17

GC content: 45.02

Gene sequence:

>1044_bases
ATGATTTACCCCGTTATTTGGCAAAATAATTGTGTCTTACTAATTGACCAAACTCGTTTACCCAATGAGTATGCAGTTGT
AGAAATTCACCGTAGTGAAGATATGGCGCGGGCGATTCAAACTATGATTGTCCGGGGTGCGCCTGCGATTGGCGTGGCGG
CGGCTTATGGGATGTATTTGGGGGCGAGGGAAATTGAGACAGGCGAACGCCAGGAGTTTTTGCAAGAATTAGAAAAAGTA
GCACAGTTATTACGGGCTACCCGTCCCACAGCCGTCAATTTATTTTGGGCAATTAGTAGGATGCAGAAAACTGCCTATAA
GACTTTAGGAACAGTCGCCCAAATTAAAGAAAATCTCTTACAAACTGCCCAAGCCATCAACGCAGAAGACTTGCAAACTT
GTCAGGCGATCGGTGACAATGGCTTGGCTATCTTACCCAAAACACCAGAAAAGCTGACATTGCTGACCCATTGTAATGCA
GGGGCTTTAGCTACTGCTGGTTATGGTACAGCCTTGGGGGTTGTCCGTTCAGCTTGGCGAGAAGGGCGTTTAGAAAGGTT
GTTTGCTGATGAAACCCGTCCACGTCTGCAAGGTGCAAAACTTACCACTTGGGAATGTGTGCAAGAAGGTATTCCCGTAA
CGCTAATTACTGATAATATGGCAGCCCATTGCATGAAACAGGGTTTAATTCATGCTGTTGTTGTGGGTGCGGATCGAATT
GCGGCTAATGGTGATGCTGCAAATAAAATCGGCACTTATAGTTTAGCTATAGTCGCCAAAGCACATAATGTTCCTTTCTT
CGTCGCTGCGCCTGTCTCTACAATTGATTTTGAATTAGCTGATGGTAGTCAAATCCCCATTGAAGAACGCAACCCAGTAG
AAATTTATCAAGTCGGTGATACTACTTTGACACCTCCAGGCGTGAAATTCTACAATCCCGCTTTTGATGTCACCCCAGCA
GAGTTAATTACAGCCATCATTACCGAGAATGGTGCTTTTGCTCCTCATGTTTTAACTAAATCCTCACAACAAGCGGTGGT
TTAG

Upstream 100 bases:

>100_bases
ACTTTCCACAGTAGAAACTAGGGATTGGGGAGATAGGACAGATAAGGTATATTATATTCCCAATCCCCAATCCCCAATCC
CCAGTCCTCAATCCCCATCT

Downstream 100 bases:

>100_bases
TCATGCGGATATGTGACATGGACTAAGCGATCGCACTCTCTGTGATAACATTCCTACCAAAAGCAAACCATAGGCTAAGT
TTTGATTTATCATCAAGTAC

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MIYPVIWQNNCVLLIDQTRLPNEYAVVEIHRSEDMARAIQTMIVRGAPAIGVAAAYGMYLGAREIETGERQEFLQELEKV
AQLLRATRPTAVNLFWAISRMQKTAYKTLGTVAQIKENLLQTAQAINAEDLQTCQAIGDNGLAILPKTPEKLTLLTHCNA
GALATAGYGTALGVVRSAWREGRLERLFADETRPRLQGAKLTTWECVQEGIPVTLITDNMAAHCMKQGLIHAVVVGADRI
AANGDAANKIGTYSLAIVAKAHNVPFFVAAPVSTIDFELADGSQIPIEERNPVEIYQVGDTTLTPPGVKFYNPAFDVTPA
ELITAIITENGAFAPHVLTKSSQQAVV

Sequences:

>Translated_347_residues
MIYPVIWQNNCVLLIDQTRLPNEYAVVEIHRSEDMARAIQTMIVRGAPAIGVAAAYGMYLGAREIETGERQEFLQELEKV
AQLLRATRPTAVNLFWAISRMQKTAYKTLGTVAQIKENLLQTAQAINAEDLQTCQAIGDNGLAILPKTPEKLTLLTHCNA
GALATAGYGTALGVVRSAWREGRLERLFADETRPRLQGAKLTTWECVQEGIPVTLITDNMAAHCMKQGLIHAVVVGADRI
AANGDAANKIGTYSLAIVAKAHNVPFFVAAPVSTIDFELADGSQIPIEERNPVEIYQVGDTTLTPPGVKFYNPAFDVTPA
ELITAIITENGAFAPHVLTKSSQQAVV
>Mature_347_residues
MIYPVIWQNNCVLLIDQTRLPNEYAVVEIHRSEDMARAIQTMIVRGAPAIGVAAAYGMYLGAREIETGERQEFLQELEKV
AQLLRATRPTAVNLFWAISRMQKTAYKTLGTVAQIKENLLQTAQAINAEDLQTCQAIGDNGLAILPKTPEKLTLLTHCNA
GALATAGYGTALGVVRSAWREGRLERLFADETRPRLQGAKLTTWECVQEGIPVTLITDNMAAHCMKQGLIHAVVVGADRI
AANGDAANKIGTYSLAIVAKAHNVPFFVAAPVSTIDFELADGSQIPIEERNPVEIYQVGDTTLTPPGVKFYNPAFDVTPA
ELITAIITENGAFAPHVLTKSSQQAVV

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=351, Percent_Identity=44.1595441595442, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI23943880, Length=149, Percent_Identity=57.7181208053691, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI78000158, Length=186, Percent_Identity=31.1827956989247, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI78000156, Length=186, Percent_Identity=31.1827956989247, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI187607323, Length=186, Percent_Identity=31.1827956989247, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4503503, Length=227, Percent_Identity=25.9911894273128, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17557462, Length=331, Percent_Identity=37.1601208459215, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17557123, Length=186, Percent_Identity=29.0322580645161, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6325375, Length=388, Percent_Identity=35.0515463917526, Blast_Score=203, Evalue=4e-53,
Organism=Drosophila melanogaster, GI21357667, Length=350, Percent_Identity=42.8571428571429, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24651647, Length=350, Percent_Identity=42.8571428571429, Blast_Score=263, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 37634; Mature: 37634

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYPVIWQNNCVLLIDQTRLPNEYAVVEIHRSEDMARAIQTMIVRGAPAIGVAAAYGMYL
CEEEEEECCCEEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GAREIETGERQEFLQELEKVAQLLRATRPTAVNLFWAISRMQKTAYKTLGTVAQIKENLL
CCHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTAQAINAEDLQTCQAIGDNGLAILPKTPEKLTLLTHCNAGALATAGYGTALGVVRSAWR
HHHHHCCHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHH
EGRLERLFADETRPRLQGAKLTTWECVQEGIPVTLITDNMAAHCMKQGLIHAVVVGADRI
HCHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEECCHHHHHHHHCCCEEEEECCCCE
AANGDAANKIGTYSLAIVAKAHNVPFFVAAPVSTIDFELADGSQIPIEERNPVEIYQVGD
ECCCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEECC
TTLTPPGVKFYNPAFDVTPAELITAIITENGAFAPHVLTKSSQQAVV
CEECCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCHHCCCCCCCCCC
>Mature Secondary Structure
MIYPVIWQNNCVLLIDQTRLPNEYAVVEIHRSEDMARAIQTMIVRGAPAIGVAAAYGMYL
CEEEEEECCCEEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GAREIETGERQEFLQELEKVAQLLRATRPTAVNLFWAISRMQKTAYKTLGTVAQIKENLL
CCHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTAQAINAEDLQTCQAIGDNGLAILPKTPEKLTLLTHCNAGALATAGYGTALGVVRSAWR
HHHHHCCHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHH
EGRLERLFADETRPRLQGAKLTTWECVQEGIPVTLITDNMAAHCMKQGLIHAVVVGADRI
HCHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEECCHHHHHHHHCCCEEEEECCCCE
AANGDAANKIGTYSLAIVAKAHNVPFFVAAPVSTIDFELADGSQIPIEERNPVEIYQVGD
ECCCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEECC
TTLTPPGVKFYNPAFDVTPAELITAIITENGAFAPHVLTKSSQQAVV
CEECCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA