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The map label for this gene is mpg1 [H]

Identifier: 17230892

GI number: 17230892

Start: 4110317

End: 4111486

Strand: Direct

Name: mpg1 [H]

Synonym: alr3400

Alternate gene names: 17230892

Gene position: 4110317-4111486 (Clockwise)

Preceding gene: 17230891

Following gene: 17230894

Centisome position: 64.09

GC content: 45.81

Gene sequence:

>1170_bases
ATGAAAGCGATGATTCTCGCAGCAGGTAAGGGTACTCGCGTTCGTCCGATTACCTATACGATTCCCAAACCGATGATTCC
CATCCTGCAAAAGCCAGTGATGGAATTTTTACTGGAACTTTTACGTCAACATGGTTTTGACCAGATTATGGTCAACGTCA
GCCATCTGGCTGAAGAAATTGAAAACTATTTTCGTGATGGTCAACGGTTTGGTGTACAGATTGCCTATTCTTTTGAAGGC
AAAATTGATGATGAAGGTAAGCTGGTAGGGGAAGCAATAGGTTCTGCTGGAGGGATGCGACGCATCCAAGATTTTTCACC
ATTTTTTGATGATACCTTTGTGGTGTTGTGCGGCGACGCTTTGATTGACTTAGATTTGACGGCAGCAGTGAAGTGGCATA
AATCCAAAGGCTCCATCGCTACTATCATCACCAAAACTGTCCCCGAAGAAGAAGTTTCTAGTTATGGTGTGGTCGTCACT
GATGAGAATAGTCGGGTTAAAGCCTTCCAAGAAAAACCATCGATAGAGGAAGCACTTAGTACTAATATCAACACAGGTAT
CTACATTTTTGAGCCAGAGGTGTTTAATTACATACCTTCTGGTGTGGAATATGACATCGGTGGTCAACTATTCCCCAAAC
TGGTAGAAATTGGTGCGCCCTTCTATGCGATCGCAATGGATTTTGAATGGGTGGATATTGGTAAAGTACCAGACTACTGG
CGGGCAATTCGCGGCGTTTTACAAGGGGATATTAAGAATGTGCAGATTCCCGGTCATGAGGTTGCCCCTGGTATCTATAC
TGGCTTAAATGTGGCAGTGAATTGGGACAAAGTAGATATCACTGGCCCAGTTTACATTGGTGGCATGACTCGCATCGAAG
ATGGCGCGAAAATTGTCGGCCCGGCAATGATTGGCCCCAATTGCTGGATATGCGGTGAAGCCACTGTTGATAACAGTGTC
ATCTTTGAATGGTCACGATTAGGGCATGGAGCCAGGCTAGTTGATAAACTGGTGTTCGGGCGTTACTGCGTCGATAAAAC
AGGAGCTGCTATTGACGTACAAGCTGCTGCTTTAGATTGGCTGATTACCGATGCCCGGCAAACACCACCAGAACATACCC
CAGTGGAACGGCAAGCGATCGCCGAATTGTTGGGAACAAACGCAACTTAG

Upstream 100 bases:

>100_bases
TATCCCTGTTGTCAGGGGTTACTTAGAGCAGAAATCAAAAACTGATGATTAAGTATCACACAATGAAAGTAAACTGGCTT
GTGGTTGAGGAATAAACTTT

Downstream 100 bases:

>100_bases
TCATTAGTCATGAGTCAGTTGTCAGTTGCAATTTCTACTGACAACTGACAACTAACCACTAACCACTAACTATTTAAGTA
TGTGTATCTTCTGAGACTTT

Product: mannose-1-phosphate guanyltransferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKAMILAAGKGTRVRPITYTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEEIENYFRDGQRFGVQIAYSFEG
KIDDEGKLVGEAIGSAGGMRRIQDFSPFFDDTFVVLCGDALIDLDLTAAVKWHKSKGSIATIITKTVPEEEVSSYGVVVT
DENSRVKAFQEKPSIEEALSTNINTGIYIFEPEVFNYIPSGVEYDIGGQLFPKLVEIGAPFYAIAMDFEWVDIGKVPDYW
RAIRGVLQGDIKNVQIPGHEVAPGIYTGLNVAVNWDKVDITGPVYIGGMTRIEDGAKIVGPAMIGPNCWICGEATVDNSV
IFEWSRLGHGARLVDKLVFGRYCVDKTGAAIDVQAAALDWLITDARQTPPEHTPVERQAIAELLGTNAT

Sequences:

>Translated_389_residues
MKAMILAAGKGTRVRPITYTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEEIENYFRDGQRFGVQIAYSFEG
KIDDEGKLVGEAIGSAGGMRRIQDFSPFFDDTFVVLCGDALIDLDLTAAVKWHKSKGSIATIITKTVPEEEVSSYGVVVT
DENSRVKAFQEKPSIEEALSTNINTGIYIFEPEVFNYIPSGVEYDIGGQLFPKLVEIGAPFYAIAMDFEWVDIGKVPDYW
RAIRGVLQGDIKNVQIPGHEVAPGIYTGLNVAVNWDKVDITGPVYIGGMTRIEDGAKIVGPAMIGPNCWICGEATVDNSV
IFEWSRLGHGARLVDKLVFGRYCVDKTGAAIDVQAAALDWLITDARQTPPEHTPVERQAIAELLGTNAT
>Mature_389_residues
MKAMILAAGKGTRVRPITYTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEEIENYFRDGQRFGVQIAYSFEG
KIDDEGKLVGEAIGSAGGMRRIQDFSPFFDDTFVVLCGDALIDLDLTAAVKWHKSKGSIATIITKTVPEEEVSSYGVVVT
DENSRVKAFQEKPSIEEALSTNINTGIYIFEPEVFNYIPSGVEYDIGGQLFPKLVEIGAPFYAIAMDFEWVDIGKVPDYW
RAIRGVLQGDIKNVQIPGHEVAPGIYTGLNVAVNWDKVDITGPVYIGGMTRIEDGAKIVGPAMIGPNCWICGEATVDNSV
IFEWSRLGHGARLVDKLVFGRYCVDKTGAAIDVQAAALDWLITDARQTPPEHTPVERQAIAELLGTNAT

Specific function: Glycogen biosynthesis; first step. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=354, Percent_Identity=29.9435028248588, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI11761619, Length=306, Percent_Identity=31.3725490196078, Blast_Score=131, Evalue=1e-30,
Organism=Escherichia coli, GI1789837, Length=265, Percent_Identity=25.2830188679245, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790224, Length=203, Percent_Identity=26.6009852216749, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788351, Length=196, Percent_Identity=28.0612244897959, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI133931050, Length=346, Percent_Identity=30.635838150289, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17509979, Length=358, Percent_Identity=24.8603351955307, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17509981, Length=347, Percent_Identity=24.207492795389, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320148, Length=354, Percent_Identity=27.9661016949153, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21355443, Length=334, Percent_Identity=30.5389221556886, Blast_Score=141, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24644084, Length=334, Percent_Identity=30.5389221556886, Blast_Score=141, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24653912, Length=205, Percent_Identity=28.780487804878, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 42784; Mature: 42784

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAMILAAGKGTRVRPITYTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEEI
CCEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHH
ENYFRDGQRFGVQIAYSFEGKIDDEGKLVGEAIGSAGGMRRIQDFSPFFDDTFVVLCGDA
HHHHHCCCEEEEEEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEECCE
LIDLDLTAAVKWHKSKGSIATIITKTVPEEEVSSYGVVVTDENSRVKAFQEKPSIEEALS
EEEEEEEEEEEEECCCCCEEEEEEECCCHHHHHCCCEEEECCCCCCHHHHCCCCHHHHHH
TNINTGIYIFEPEVFNYIPSGVEYDIGGQLFPKLVEIGAPFYAIAMDFEWVDIGKVPDYW
CCCCCCEEEECCHHHHHCCCCCEECCCCHHHHHHHHHCCCEEEEEEEEEEEECCCCCHHH
RAIRGVLQGDIKNVQIPGHEVAPGIYTGLNVAVNWDKVDITGPVYIGGMTRIEDGAKIVG
HHHHHHHHCCCCEEECCCCCCCCCEEECCEEEEEECEEEECCCEEECCCEEECCCCEEEC
PAMIGPNCWICGEATVDNSVIFEWSRLGHGARLVDKLVFGRYCVDKTGAAIDVQAAALDW
CEEECCCEEEECCCCCCCCEEEEHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
LITDARQTPPEHTPVERQAIAELLGTNAT
HHCCCCCCCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MKAMILAAGKGTRVRPITYTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEEI
CCEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHH
ENYFRDGQRFGVQIAYSFEGKIDDEGKLVGEAIGSAGGMRRIQDFSPFFDDTFVVLCGDA
HHHHHCCCEEEEEEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEECCE
LIDLDLTAAVKWHKSKGSIATIITKTVPEEEVSSYGVVVTDENSRVKAFQEKPSIEEALS
EEEEEEEEEEEEECCCCCEEEEEEECCCHHHHHCCCEEEECCCCCCHHHHCCCCHHHHHH
TNINTGIYIFEPEVFNYIPSGVEYDIGGQLFPKLVEIGAPFYAIAMDFEWVDIGKVPDYW
CCCCCCEEEECCHHHHHCCCCCEECCCCHHHHHHHHHCCCEEEEEEEEEEEECCCCCHHH
RAIRGVLQGDIKNVQIPGHEVAPGIYTGLNVAVNWDKVDITGPVYIGGMTRIEDGAKIVG
HHHHHHHHCCCCEEECCCCCCCCCEEECCEEEEEECEEEECCCEEECCCEEECCCCEEEC
PAMIGPNCWICGEATVDNSVIFEWSRLGHGARLVDKLVFGRYCVDKTGAAIDVQAAALDW
CEEECCCEEEECCCCCCCCEEEEHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
LITDARQTPPEHTPVERQAIAELLGTNAT
HHCCCCCCCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]