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The map label for this gene is ndk [H]

Identifier: 17230894

GI number: 17230894

Start: 4113842

End: 4114195

Strand: Direct

Name: ndk [H]

Synonym: alr3402

Alternate gene names: 17230894

Gene position: 4113842-4114195 (Clockwise)

Preceding gene: 17230892

Following gene: 17230897

Centisome position: 64.14

GC content: 46.89

Gene sequence:

>354_bases
GTGGGTTTGAAGTTCCTCCAAGTCAGTAAAGAATTGGCTGAACAACATTATGGCGTACACCGCGAAAGACCATTCTTTCC
TAGCTTAGTGGAATTTATCACCTCTGGCCCGGTGGTAGCGATGGTTTGGGAAGGTGATGGCGTGATTGCTTCTGCCAGAA
AAATTATTGGTGCGACCAATCCCCTAACAGCAGAACCCGGAACAATTCGGGGCGATTTTGGTATTAACATCGGTCGCAAC
CTCATCCACGGTTCTGATGCACCAGAAACCGCACAAAAGGAAGTAAGCCTATGGTTTACAGATGCAGAATTAGTCAATTG
GCAACCCCATTTAACACCTTGGTTGCACGAGTAA

Upstream 100 bases:

>100_bases
AGTTTTGGAACGCACATTCTTAGCAATTAAGCCTGATGGCGTACAGCGTGGACTGGTTGGGGAAATTATCCGTCGCTTTG
AAACAAAAGGTTTTACCCTT

Downstream 100 bases:

>100_bases
TTAGTTAGGGTGTGGGGAGTAGGGAGTACTGAGTGAAATATTCTAGTTACTAGTTTTCATTTCCCAGTCCCCAGTCCCCA
GTCCCTAATTCCCTTACTTC

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 117; Mature: 116

Protein sequence:

>117_residues
MGLKFLQVSKELAEQHYGVHRERPFFPSLVEFITSGPVVAMVWEGDGVIASARKIIGATNPLTAEPGTIRGDFGINIGRN
LIHGSDAPETAQKEVSLWFTDAELVNWQPHLTPWLHE

Sequences:

>Translated_117_residues
MGLKFLQVSKELAEQHYGVHRERPFFPSLVEFITSGPVVAMVWEGDGVIASARKIIGATNPLTAEPGTIRGDFGINIGRN
LIHGSDAPETAQKEVSLWFTDAELVNWQPHLTPWLHE
>Mature_116_residues
GLKFLQVSKELAEQHYGVHRERPFFPSLVEFITSGPVVAMVWEGDGVIASARKIIGATNPLTAEPGTIRGDFGINIGRNL
IHGSDAPETAQKEVSLWFTDAELVNWQPHLTPWLHE

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI37693993, Length=117, Percent_Identity=53.8461538461538, Blast_Score=141, Evalue=1e-34,
Organism=Homo sapiens, GI66392203, Length=117, Percent_Identity=52.1367521367521, Blast_Score=139, Evalue=4e-34,
Organism=Homo sapiens, GI66392227, Length=117, Percent_Identity=52.1367521367521, Blast_Score=139, Evalue=4e-34,
Organism=Homo sapiens, GI66392205, Length=117, Percent_Identity=52.1367521367521, Blast_Score=139, Evalue=4e-34,
Organism=Homo sapiens, GI4505409, Length=117, Percent_Identity=52.1367521367521, Blast_Score=139, Evalue=4e-34,
Organism=Homo sapiens, GI66392192, Length=117, Percent_Identity=52.1367521367521, Blast_Score=139, Evalue=4e-34,
Organism=Homo sapiens, GI4557797, Length=117, Percent_Identity=52.1367521367521, Blast_Score=138, Evalue=8e-34,
Organism=Homo sapiens, GI38045913, Length=117, Percent_Identity=52.1367521367521, Blast_Score=138, Evalue=9e-34,
Organism=Homo sapiens, GI4826862, Length=107, Percent_Identity=50.4672897196262, Blast_Score=125, Evalue=7e-30,
Organism=Homo sapiens, GI5031951, Length=109, Percent_Identity=34.8623853211009, Blast_Score=68, Evalue=2e-12,
Organism=Homo sapiens, GI7019465, Length=100, Percent_Identity=35, Blast_Score=66, Evalue=5e-12,
Organism=Homo sapiens, GI37574614, Length=100, Percent_Identity=35, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788866, Length=105, Percent_Identity=40.9523809523809, Blast_Score=93, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17506807, Length=118, Percent_Identity=48.3050847457627, Blast_Score=128, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17507605, Length=91, Percent_Identity=38.4615384615385, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322783, Length=117, Percent_Identity=49.5726495726496, Blast_Score=142, Evalue=1e-35,
Organism=Drosophila melanogaster, GI45549037, Length=117, Percent_Identity=56.4102564102564, Blast_Score=147, Evalue=1e-36,
Organism=Drosophila melanogaster, GI18860097, Length=95, Percent_Identity=34.7368421052632, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564
- InterPro:   IPR023005 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 12975; Mature: 12844

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLKFLQVSKELAEQHYGVHRERPFFPSLVEFITSGPVVAMVWEGDGVIASARKIIGATN
CCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCEEEHHHHHHCCCC
PLTAEPGTIRGDFGINIGRNLIHGSDAPETAQKEVSLWFTDAELVNWQPHLTPWLHE
CCCCCCCCEECCCCCCCCCCEECCCCCCCCCCCEEEEEEECHHEECCCCCCCCCCCC
>Mature Secondary Structure 
GLKFLQVSKELAEQHYGVHRERPFFPSLVEFITSGPVVAMVWEGDGVIASARKIIGATN
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCEEEHHHHHHCCCC
PLTAEPGTIRGDFGINIGRNLIHGSDAPETAQKEVSLWFTDAELVNWQPHLTPWLHE
CCCCCCCCEECCCCCCCCCCEECCCCCCCCCCCEEEEEEECHHEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA