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The map label for this gene is moaC [H]

Identifier: 17230874

GI number: 17230874

Start: 4093990

End: 4094496

Strand: Direct

Name: moaC [H]

Synonym: alr3382

Alternate gene names: 17230874

Gene position: 4093990-4094496 (Clockwise)

Preceding gene: 17230873

Following gene: 17230876

Centisome position: 63.83

GC content: 44.58

Gene sequence:

>507_bases
ATGCAAGCCCCTTTTCCCAAAAATTCTGCAAACCTTACTCATCTAGATGGCCAGGGACAGGCACAGATGGTGGATGTGTC
TGATAAAGCACAAACAATTCGCCAGGCGGTGGCGGCGGCTCAGGTACGGATGCTACCTGCAACTTTAGAAGCCATCCAAG
CTGGTAACACACCTAAAGGTGATGTATTAGCCACCGCTAGGCTAGCTGGGATTATGGCTGCTAAACAAACAGCCAATTTG
ATTCCCCTGTGTCATCCTTTGCCATTACAAAAAGTTGCGGTCGAGATTACGCCAGACCCCCAACTTCCTGGTTATCAAAT
CCAAGCCACAGTCAAAACTAAAGCCGAAACTGGTGTGGAAATGGAAGCTTTAACTGCCGTTTCTATTGCTGCTTTAACTT
TGTATGATATGGCAAAAGCTCTAGAAAAATCGATGCAAATTGAATCAATTAGATTAGTTAGTAAAACTGGCGGAAAATCA
GGAGATTATTTTCCACCAGCACCATAA

Upstream 100 bases:

>100_bases
GGATTCGAACCCCCGACACCGTGGTCCGTAGCCACGTGCTCTAGTCCACTGAGCTACACGCCCTTACAAGAAATATATAC
TATCACCATTTTTCCTAATT

Downstream 100 bases:

>100_bases
TTTAATCTATTTCACCTATAGCTTTGTTCACATCTGTGGGGTTTTCATATTCCTCATCTTCTGGCAATTGCTCTAATAGG
GAAATTATTTTTTGATCGGC

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MQAPFPKNSANLTHLDGQGQAQMVDVSDKAQTIRQAVAAAQVRMLPATLEAIQAGNTPKGDVLATARLAGIMAAKQTANL
IPLCHPLPLQKVAVEITPDPQLPGYQIQATVKTKAETGVEMEALTAVSIAALTLYDMAKALEKSMQIESIRLVSKTGGKS
GDYFPPAP

Sequences:

>Translated_168_residues
MQAPFPKNSANLTHLDGQGQAQMVDVSDKAQTIRQAVAAAQVRMLPATLEAIQAGNTPKGDVLATARLAGIMAAKQTANL
IPLCHPLPLQKVAVEITPDPQLPGYQIQATVKTKAETGVEMEALTAVSIAALTLYDMAKALEKSMQIESIRLVSKTGGKS
GDYFPPAP
>Mature_168_residues
MQAPFPKNSANLTHLDGQGQAQMVDVSDKAQTIRQAVAAAQVRMLPATLEAIQAGNTPKGDVLATARLAGIMAAKQTANL
IPLCHPLPLQKVAVEITPDPQLPGYQIQATVKTKAETGVEMEALTAVSIAALTLYDMAKALEKSMQIESIRLVSKTGGKS
GDYFPPAP

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=154, Percent_Identity=54.5454545454545, Blast_Score=168, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=44.9664429530201, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28574490, Length=153, Percent_Identity=50.9803921568627, Blast_Score=147, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28574492, Length=146, Percent_Identity=47.945205479452, Blast_Score=125, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17688; Mature: 17688

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAPFPKNSANLTHLDGQGQAQMVDVSDKAQTIRQAVAAAQVRMLPATLEAIQAGNTPKG
CCCCCCCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DVLATARLAGIMAAKQTANLIPLCHPLPLQKVAVEITPDPQLPGYQIQATVKTKAETGVE
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCCC
MEALTAVSIAALTLYDMAKALEKSMQIESIRLVSKTGGKSGDYFPPAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHCCCCCCCCCCCCC
>Mature Secondary Structure
MQAPFPKNSANLTHLDGQGQAQMVDVSDKAQTIRQAVAAAQVRMLPATLEAIQAGNTPKG
CCCCCCCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DVLATARLAGIMAAKQTANLIPLCHPLPLQKVAVEITPDPQLPGYQIQATVKTKAETGVE
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCCC
MEALTAVSIAALTLYDMAKALEKSMQIESIRLVSKTGGKSGDYFPPAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA