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The map label for this gene is gpmB [H]

Identifier: 17230830

GI number: 17230830

Start: 4033727

End: 4035076

Strand: Direct

Name: gpmB [H]

Synonym: alr3338

Alternate gene names: 17230830

Gene position: 4033727-4035076 (Clockwise)

Preceding gene: 17230829

Following gene: 17230831

Centisome position: 62.89

GC content: 45.33

Gene sequence:

>1350_bases
ATGACTCGTGTCATTATTGTGCGTCACGGCCAAAGTACTTATAACATCGAACGGCGCATCCAAGGACGTGCTGACGTATC
AACATTAACGGAGCGAGGTCGTAGTGACGCTAGTAAGGTAGGCAAGGCCCTCACTAACATTTCCTTTAAGGCAATTTACA
CTAGCCCACTCCAGCGAGCAAAACAAACAGCAGAGATTATTCATAGTGAGCTGGCAAATGAGGCAGTTCAGTCTGCTGAT
GTGCAGATTTCTGAATTGTTAAGAGAAATAGACTTGCCTTTGTGGGAAAAACTGCTGACATCCGAGGTCAAGGAAAAGTT
TCCCGAAGATTACCGCATTTGGCACGAAAAACCCCAGGAACTACAAATGTTAGTGAACGACAATGGGGTGACAAGAGAAC
ATTTTCCAGTTCTATCTTTATACGAACAGGCGCGGCAGTTTTGGCAAAACATTTTGCCCAATCATCGCGGTGAAAGCATT
CTCATCGTTGGACACAACGGCATTAATCGCGCCCTCATCAGCACAGCCTTGGGTGTTCACCCCAGTCGTTACCATGCCAT
ACAGCAATCTAACTGTGGAATCAGTGTATTAAATTTTGCTGGAGGACTGGGTGAACCAGTGCAACTAGAGTCGATGAATC
AAACCCAACACACAGGCGAGACTCTACCTTCCTTGCGTCCTGGTCATCAGGGAGTGAGATTGTTATTGGTGCGTCACGGT
GAAACTGAATGGAATCGCCAAACTAGGTTTCAGGGACAAATTGACGTTCCCCTCAACGATAACGGTAGACAACAAGCACA
AAAAGCCGGGGTGTTTCTGCAAAATGTAGCAATTGACTTTGCTGTAAGTAGTTCTATGCTGCGTCCCAAAGAAACAGCCG
AGATTATCTTGCGCCACCATCCAAGTATCAATTTGGAGTTGCAAGACGGTTTAAGAGAAATCAGTCACGGACTTTGGGAA
GGAAAACTAGAAGCCGAAATAGAAGAGGAATTTCCTGGTGAATTAGAGCGTTGGCGGACTATACCAGGCCAGGTACAAAT
GCCGGAAGGTGAGAATTTACAGCAAGTGTGGGAACGTAGCACGGAAGCCTGGCAAAATATTGTGCAAACAGCCTTAGATA
ATCAACGCCAAACAGGGTTAATCGTGGCTCACGATGCCACAAATAAAACCTTACTGTGTCATATTCTCGGTTTACCCACA
GACAATTTCTGGAATTTTCGCCAAGGTAATGGTGCTGTTAGTGTCATTGATTACCCCTCTGGATTAAATGGTGTACCAGT
ACTGCAAGCCATGAATATTACTACTCATTTGGGTGGTGTATTAGATAAAACCGCAGCTGGAGCATTATAG

Upstream 100 bases:

>100_bases
CCCTTACACCCTGATTAAATTGCCAAAAACCAATCTGAAGGATAATTCTGCAAGCAGTTTGCAGTAAAATTAGTCCTTTA
GATAGAGGAGGGCAAGACGG

Downstream 100 bases:

>100_bases
GCAAAATATATATCACAATAGACAAGCAGTCCCAGCACTGATAGGTTACATGACAACTGAACTTCTGCAACAAGTAAGGG
TAATCGACCCGGTTTCGGGT

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTRVIIVRHGQSTYNIERRIQGRADVSTLTERGRSDASKVGKALTNISFKAIYTSPLQRAKQTAEIIHSELANEAVQSAD
VQISELLREIDLPLWEKLLTSEVKEKFPEDYRIWHEKPQELQMLVNDNGVTREHFPVLSLYEQARQFWQNILPNHRGESI
LIVGHNGINRALISTALGVHPSRYHAIQQSNCGISVLNFAGGLGEPVQLESMNQTQHTGETLPSLRPGHQGVRLLLVRHG
ETEWNRQTRFQGQIDVPLNDNGRQQAQKAGVFLQNVAIDFAVSSSMLRPKETAEIILRHHPSINLELQDGLREISHGLWE
GKLEAEIEEEFPGELERWRTIPGQVQMPEGENLQQVWERSTEAWQNIVQTALDNQRQTGLIVAHDATNKTLLCHILGLPT
DNFWNFRQGNGAVSVIDYPSGLNGVPVLQAMNITTHLGGVLDKTAAGAL

Sequences:

>Translated_449_residues
MTRVIIVRHGQSTYNIERRIQGRADVSTLTERGRSDASKVGKALTNISFKAIYTSPLQRAKQTAEIIHSELANEAVQSAD
VQISELLREIDLPLWEKLLTSEVKEKFPEDYRIWHEKPQELQMLVNDNGVTREHFPVLSLYEQARQFWQNILPNHRGESI
LIVGHNGINRALISTALGVHPSRYHAIQQSNCGISVLNFAGGLGEPVQLESMNQTQHTGETLPSLRPGHQGVRLLLVRHG
ETEWNRQTRFQGQIDVPLNDNGRQQAQKAGVFLQNVAIDFAVSSSMLRPKETAEIILRHHPSINLELQDGLREISHGLWE
GKLEAEIEEEFPGELERWRTIPGQVQMPEGENLQQVWERSTEAWQNIVQTALDNQRQTGLIVAHDATNKTLLCHILGLPT
DNFWNFRQGNGAVSVIDYPSGLNGVPVLQAMNITTHLGGVLDKTAAGAL
>Mature_448_residues
TRVIIVRHGQSTYNIERRIQGRADVSTLTERGRSDASKVGKALTNISFKAIYTSPLQRAKQTAEIIHSELANEAVQSADV
QISELLREIDLPLWEKLLTSEVKEKFPEDYRIWHEKPQELQMLVNDNGVTREHFPVLSLYEQARQFWQNILPNHRGESIL
IVGHNGINRALISTALGVHPSRYHAIQQSNCGISVLNFAGGLGEPVQLESMNQTQHTGETLPSLRPGHQGVRLLLVRHGE
TEWNRQTRFQGQIDVPLNDNGRQQAQKAGVFLQNVAIDFAVSSSMLRPKETAEIILRHHPSINLELQDGLREISHGLWEG
KLEAEIEEEFPGELERWRTIPGQVQMPEGENLQQVWERSTEAWQNIVQTALDNQRQTGLIVAHDATNKTLLCHILGLPTD
NFWNFRQGNGAVSVIDYPSGLNGVPVLQAMNITTHLGGVLDKTAAGAL

Specific function: Unknown

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Homo sapiens, GI9966849, Length=148, Percent_Identity=33.7837837837838, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1790856, Length=198, Percent_Identity=32.8282828282828, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786857, Length=202, Percent_Identity=26.2376237623762, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322697, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 50379; Mature: 50247

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVIIVRHGQSTYNIERRIQGRADVSTLTERGRSDASKVGKALTNISFKAIYTSPLQRA
CCEEEEEECCCCCHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCEEEEEEHHHHHHH
KQTAEIIHSELANEAVQSADVQISELLREIDLPLWEKLLTSEVKEKFPEDYRIWHEKPQE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHCCCCHH
LQMLVNDNGVTREHFPVLSLYEQARQFWQNILPNHRGESILIVGHNGINRALISTALGVH
HHEEECCCCCCHHHCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCC
PSRYHAIQQSNCGISVLNFAGGLGEPVQLESMNQTQHTGETLPSLRPGHQGVRLLLVRHG
CHHHHHHHCCCCCEEEEECCCCCCCCEEECCCCCHHHHHHHCCCCCCCCCCEEEEEEECC
ETEWNRQTRFQGQIDVPLNDNGRQQAQKAGVFLQNVAIDFAVSSSMLRPKETAEIILRHH
CCCCCCCCCCCCEEECCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
PSINLELQDGLREISHGLWEGKLEAEIEEEFPGELERWRTIPGQVQMPEGENLQQVWERS
CCCEEEHHHHHHHHHHHHCCCCHHCHHHHHCCCHHHHHCCCCCCEECCCCCCHHHHHHHH
TEAWQNIVQTALDNQRQTGLIVAHDATNKTLLCHILGLPTDNFWNFRQGNGAVSVIDYPS
HHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCEECCCCEEEEEECCC
GLNGVPVLQAMNITTHLGGVLDKTAAGAL
CCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TRVIIVRHGQSTYNIERRIQGRADVSTLTERGRSDASKVGKALTNISFKAIYTSPLQRA
CEEEEEECCCCCHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCEEEEEEHHHHHHH
KQTAEIIHSELANEAVQSADVQISELLREIDLPLWEKLLTSEVKEKFPEDYRIWHEKPQE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHCCCCHH
LQMLVNDNGVTREHFPVLSLYEQARQFWQNILPNHRGESILIVGHNGINRALISTALGVH
HHEEECCCCCCHHHCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCC
PSRYHAIQQSNCGISVLNFAGGLGEPVQLESMNQTQHTGETLPSLRPGHQGVRLLLVRHG
CHHHHHHHCCCCCEEEEECCCCCCCCEEECCCCCHHHHHHHCCCCCCCCCCEEEEEEECC
ETEWNRQTRFQGQIDVPLNDNGRQQAQKAGVFLQNVAIDFAVSSSMLRPKETAEIILRHH
CCCCCCCCCCCCEEECCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
PSINLELQDGLREISHGLWEGKLEAEIEEEFPGELERWRTIPGQVQMPEGENLQQVWERS
CCCEEEHHHHHHHHHHHHCCCCHHCHHHHHCCCHHHHHCCCCCCEECCCCCCHHHHHHHH
TEAWQNIVQTALDNQRQTGLIVAHDATNKTLLCHILGLPTDNFWNFRQGNGAVSVIDYPS
HHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCEECCCCEEEEEECCC
GLNGVPVLQAMNITTHLGGVLDKTAAGAL
CCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA