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The map label for this gene is gntK [H]

Identifier: 17230578

GI number: 17230578

Start: 3734056

End: 3734538

Strand: Direct

Name: gntK [H]

Synonym: alr3086

Alternate gene names: 17230578

Gene position: 3734056-3734538 (Clockwise)

Preceding gene: 17230577

Following gene: 17230580

Centisome position: 58.22

GC content: 38.51

Gene sequence:

>483_bases
ATGATAATTATCATCATGGGTGTATCTGGTTCCGGTAAAACCACCATCGGACAAATGTTGGCGGAATCTTTACACTGGGA
ATTTCATGATGCTGACAGTTTCCACTCACCAGACAATATTGAAAAAATGCGGCGTGGTATTCCTCTGGATGATAACGATA
GAATACCCTGGTTACAAAGTTTGCAAACCGCTATTATCAATTGGCTGCAAGACAATAGAAATGTTGTCTTAGCCTGTTCT
GCCCTCAAAGCTAGTTATCGGCAATTCTTAGTTTTAGATAGTGATATTAAACTCGTCTACCTGCAAGGGACATTTGAACT
CATTCAAACAAGACTGCAAAAGCGTGAGAATCATTTTATGAATAGAGAATTGCTCACAAGTCAATTTGCATCACTTGAGG
AACCGGATAATGTCATACTTGTAGATATTTCCCAGTCGCCTCAAGTTATTGTACAAGCTATTAGAACCATGATAAAAGTT
TAG

Upstream 100 bases:

>100_bases
CGATCGCCTTAGGTTTAGAAGTTTTACCTTGTCGTTTTGATGTTACCCCAGAAGGCATCCGTTATCTAGGTTTAGCAAAA
CTGGTAATTTAATTTCATCA

Downstream 100 bases:

>100_bases
TAAAAAGAAGAATTTATATATTTAATTCTTCTGTTATCTACCTCATTTATTGGCAAAAATATATTATGTAAGAGCAAGAT
TAAAAAATTGAAAATCACAC

Product: gluconokinase

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MIIIIMGVSGSGKTTIGQMLAESLHWEFHDADSFHSPDNIEKMRRGIPLDDNDRIPWLQSLQTAIINWLQDNRNVVLACS
ALKASYRQFLVLDSDIKLVYLQGTFELIQTRLQKRENHFMNRELLTSQFASLEEPDNVILVDISQSPQVIVQAIRTMIKV

Sequences:

>Translated_160_residues
MIIIIMGVSGSGKTTIGQMLAESLHWEFHDADSFHSPDNIEKMRRGIPLDDNDRIPWLQSLQTAIINWLQDNRNVVLACS
ALKASYRQFLVLDSDIKLVYLQGTFELIQTRLQKRENHFMNRELLTSQFASLEEPDNVILVDISQSPQVIVQAIRTMIKV
>Mature_160_residues
MIIIIMGVSGSGKTTIGQMLAESLHWEFHDADSFHSPDNIEKMRRGIPLDDNDRIPWLQSLQTAIINWLQDNRNVVLACS
ALKASYRQFLVLDSDIKLVYLQGTFELIQTRLQKRENHFMNRELLTSQFASLEEPDNVILVDISQSPQVIVQAIRTMIKV

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=180, Percent_Identity=41.6666666666667, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI87082265, Length=163, Percent_Identity=40.4907975460123, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1790719, Length=161, Percent_Identity=39.7515527950311, Blast_Score=122, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI25146487, Length=166, Percent_Identity=42.1686746987952, Blast_Score=132, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6320454, Length=145, Percent_Identity=33.7931034482759, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 18337; Mature: 18337

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIIIMGVSGSGKTTIGQMLAESLHWEFHDADSFHSPDNIEKMRRGIPLDDNDRIPWLQS
CEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHH
LQTAIINWLQDNRNVVLACSALKASYRQFLVLDSDIKLVYLQGTFELIQTRLQKRENHFM
HHHHHHHHHHCCCCEEEEEHHHHHHHHHEEEECCCCEEEEECCHHHHHHHHHHHHHHHHH
NRELLTSQFASLEEPDNVILVDISQSPQVIVQAIRTMIKV
HHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIIIIMGVSGSGKTTIGQMLAESLHWEFHDADSFHSPDNIEKMRRGIPLDDNDRIPWLQS
CEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHH
LQTAIINWLQDNRNVVLACSALKASYRQFLVLDSDIKLVYLQGTFELIQTRLQKRENHFM
HHHHHHHHHHCCCCEEEEEHHHHHHHHHEEEECCCCEEEEECCHHHHHHHHHHHHHHHHH
NRELLTSQFASLEEPDNVILVDISQSPQVIVQAIRTMIKV
HHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]