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The map label for this gene is moeB [H]

Identifier: 17230398

GI number: 17230398

Start: 3546463

End: 3547635

Strand: Reverse

Name: moeB [H]

Synonym: all2906

Alternate gene names: 17230398

Gene position: 3547635-3546463 (Counterclockwise)

Preceding gene: 17230399

Following gene: 17230397

Centisome position: 55.31

GC content: 45.52

Gene sequence:

>1173_bases
ATGCTTAATCCCAACCTGGAAGATATCCAGTTAACTAAAGACGACTACGAACGCTACTCCCGCCACCTGATTTTGCCAGA
AGTGGGAGTGGAAGGGCAAAAACGGCTCAAAGCTGCCAGTGTACTTTGTATCGGTACAGGTGGACTAGGTTCACCACTAC
TGTTATATTTAGCCGCCGCCGGTATTGGACGCATCGGTATAGTCGATTTCGATGTCGTTGATACTTCCAACCTGCAACGC
CAAGTCATCCACGGAACATCATGGGTAGGTAAACCCAAAATTGAATCTGCAAAGAACCGCATACATGAGATTAACCCCTA
TTGTCAGGTTGACCTCTACGAAACTCGTCTCAGTTCCGAAAATGCCCTAGATATCATCAAACCTTACGATATCGTGGTGG
ATGGTACAGATAACTTCCCTACCAGATATCTAGTCAACGACGCTTGCGTATTGTTAGATAAACCCAACGTCTACGGTTCA
ATTTTCCGCTTTGAAGGACAAGCCACAGTCTTTAACTACGAAGGCGGGCCGAACTACCGCGACTTATACCCAGAACCACC
ACCACCAGGACTAGTTCCCTCCTGTGCAGAAGGTGGAGTATTAGGGATTTTGCCAGGAATTATCGGTGTAATTCAAGCCA
CGGAAACAGTGAAAATTGTTTTGGGCAATGGTAATACTCTCAGTGGTAGATTGTTGCTGTACAACGCCTTAGATATGAAA
TTCCGTGAGTTGAAACTGCGTCCCAACCCCATACGACCAGTAATTGAAAAACTGATAGATTACGAACAATTCTGTGGTAT
TCCTCAAGCCAAAGCAGCCGAGGCGCAAAAAATGCAAGAAATTCAAGAAATGACTGTTACCGAACTCAAGGAATTGCTGG
ATAGTGGGGCGAAAGATTTTGTCCTGCTAGATGTGCGTAACCCCAACGAGTACGAAATCGCCAAAATTCCTGGTTCTGTA
TTAATACCTTTACCAGACATTGAAAATGGTAATGGTGTAGCCAAAGTCAAAGAAGCCCTCAACGGACACCGCTTAATTGC
TCATTGTAAATTAGGTGGGCGATCGGCAAAAGCCCTAGCCATCCTCAAAGAATCGGGGATTGTGGGGACAAACGTTAAAG
GCGGAATCACCGCTTGGAGTCGGGAAGTAGATCCATCCGTTCCTGAATATTAA

Upstream 100 bases:

>100_bases
AATCAGAAATAATTGATAACATAACTTAAATACTTAAGACTAAAGACCGACATCATTTTTCGATACAATCAGTAGTCCGC
GCTTCCGCATTCAAACTCCT

Downstream 100 bases:

>100_bases
GACTAATAGTTGTAATGTAGAGAACAAGCGGGGGAAATTCACAACTTTGAATTTCCCCTTTTCTGTAATCTAACATTGCA
TAATTTGAATAATAGTCAAT

Product: hypothetical protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MLNPNLEDIQLTKDDYERYSRHLILPEVGVEGQKRLKAASVLCIGTGGLGSPLLLYLAAAGIGRIGIVDFDVVDTSNLQR
QVIHGTSWVGKPKIESAKNRIHEINPYCQVDLYETRLSSENALDIIKPYDIVVDGTDNFPTRYLVNDACVLLDKPNVYGS
IFRFEGQATVFNYEGGPNYRDLYPEPPPPGLVPSCAEGGVLGILPGIIGVIQATETVKIVLGNGNTLSGRLLLYNALDMK
FRELKLRPNPIRPVIEKLIDYEQFCGIPQAKAAEAQKMQEIQEMTVTELKELLDSGAKDFVLLDVRNPNEYEIAKIPGSV
LIPLPDIENGNGVAKVKEALNGHRLIAHCKLGGRSAKALAILKESGIVGTNVKGGITAWSREVDPSVPEY

Sequences:

>Translated_390_residues
MLNPNLEDIQLTKDDYERYSRHLILPEVGVEGQKRLKAASVLCIGTGGLGSPLLLYLAAAGIGRIGIVDFDVVDTSNLQR
QVIHGTSWVGKPKIESAKNRIHEINPYCQVDLYETRLSSENALDIIKPYDIVVDGTDNFPTRYLVNDACVLLDKPNVYGS
IFRFEGQATVFNYEGGPNYRDLYPEPPPPGLVPSCAEGGVLGILPGIIGVIQATETVKIVLGNGNTLSGRLLLYNALDMK
FRELKLRPNPIRPVIEKLIDYEQFCGIPQAKAAEAQKMQEIQEMTVTELKELLDSGAKDFVLLDVRNPNEYEIAKIPGSV
LIPLPDIENGNGVAKVKEALNGHRLIAHCKLGGRSAKALAILKESGIVGTNVKGGITAWSREVDPSVPEY
>Mature_390_residues
MLNPNLEDIQLTKDDYERYSRHLILPEVGVEGQKRLKAASVLCIGTGGLGSPLLLYLAAAGIGRIGIVDFDVVDTSNLQR
QVIHGTSWVGKPKIESAKNRIHEINPYCQVDLYETRLSSENALDIIKPYDIVVDGTDNFPTRYLVNDACVLLDKPNVYGS
IFRFEGQATVFNYEGGPNYRDLYPEPPPPGLVPSCAEGGVLGILPGIIGVIQATETVKIVLGNGNTLSGRLLLYNALDMK
FRELKLRPNPIRPVIEKLIDYEQFCGIPQAKAAEAQKMQEIQEMTVTELKELLDSGAKDFVLLDVRNPNEYEIAKIPGSV
LIPLPDIENGNGVAKVKEALNGHRLIAHCKLGGRSAKALAILKESGIVGTNVKGGITAWSREVDPSVPEY

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=407, Percent_Identity=43.2432432432432, Blast_Score=292, Evalue=3e-79,
Organism=Homo sapiens, GI4885649, Length=157, Percent_Identity=27.3885350318471, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI38045942, Length=189, Percent_Identity=29.1005291005291, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI38045944, Length=189, Percent_Identity=29.1005291005291, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1787048, Length=242, Percent_Identity=40.0826446280992, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI87082356, Length=242, Percent_Identity=38.0165289256198, Blast_Score=147, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17540406, Length=399, Percent_Identity=38.5964912280702, Blast_Score=250, Evalue=9e-67,
Organism=Caenorhabditis elegans, GI71984476, Length=118, Percent_Identity=34.7457627118644, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193203301, Length=166, Percent_Identity=25.3012048192771, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321903, Length=410, Percent_Identity=38.5365853658537, Blast_Score=247, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6320598, Length=144, Percent_Identity=29.8611111111111, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582879, Length=393, Percent_Identity=41.2213740458015, Blast_Score=308, Evalue=5e-84,
Organism=Drosophila melanogaster, GI24660640, Length=136, Percent_Identity=31.6176470588235, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 42654; Mature: 42654

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNPNLEDIQLTKDDYERYSRHLILPEVGVEGQKRLKAASVLCIGTGGLGSPLLLYLAAA
CCCCCCCCEEECHHHHHHHHCEEECCCCCCCHHHHHCEEEEEEEECCCCCHHHHHHHHHC
GIGRIGIVDFDVVDTSNLQRQVIHGTSWVGKPKIESAKNRIHEINPYCQVDLYETRLSSE
CCCEEEEEEEEEECCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHCCCC
NALDIIKPYDIVVDGTDNFPTRYLVNDACVLLDKPNVYGSIFRFEGQATVFNYEGGPNYR
CCEEEECCEEEEEECCCCCCCEEEECCEEEEEECCCCCEEEEEECCCEEEEEECCCCCCC
DLYPEPPPPGLVPSCAEGGVLGILPGIIGVIQATETVKIVLGNGNTLSGRLLLYNALDMK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCEEECEEEEEEECCCE
FRELKLRPNPIRPVIEKLIDYEQFCGIPQAKAAEAQKMQEIQEMTVTELKELLDSGAKDF
EEEEECCCCCCHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VLLDVRNPNEYEIAKIPGSVLIPLPDIENGNGVAKVKEALNGHRLIAHCKLGGRSAKALA
EEEEECCCCCEEEEECCCCEEEECCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCEEEE
ILKESGIVGTNVKGGITAWSREVDPSVPEY
EEECCCEEECCCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MLNPNLEDIQLTKDDYERYSRHLILPEVGVEGQKRLKAASVLCIGTGGLGSPLLLYLAAA
CCCCCCCCEEECHHHHHHHHCEEECCCCCCCHHHHHCEEEEEEEECCCCCHHHHHHHHHC
GIGRIGIVDFDVVDTSNLQRQVIHGTSWVGKPKIESAKNRIHEINPYCQVDLYETRLSSE
CCCEEEEEEEEEECCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHCCCC
NALDIIKPYDIVVDGTDNFPTRYLVNDACVLLDKPNVYGSIFRFEGQATVFNYEGGPNYR
CCEEEECCEEEEEECCCCCCCEEEECCEEEEEECCCCCEEEEEECCCEEEEEECCCCCCC
DLYPEPPPPGLVPSCAEGGVLGILPGIIGVIQATETVKIVLGNGNTLSGRLLLYNALDMK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCEEECEEEEEEECCCE
FRELKLRPNPIRPVIEKLIDYEQFCGIPQAKAAEAQKMQEIQEMTVTELKELLDSGAKDF
EEEEECCCCCCHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VLLDVRNPNEYEIAKIPGSVLIPLPDIENGNGVAKVKEALNGHRLIAHCKLGGRSAKALA
EEEEECCCCCEEEEECCCCEEEECCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCEEEE
ILKESGIVGTNVKGGITAWSREVDPSVPEY
EEECCCEEECCCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]