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The map label for this gene is eryA [H]

Identifier: 17230138

GI number: 17230138

Start: 3182357

End: 3186823

Strand: Reverse

Name: eryA [H]

Synonym: all2646

Alternate gene names: 17230138

Gene position: 3186823-3182357 (Counterclockwise)

Preceding gene: 17230139

Following gene: 17230137

Centisome position: 49.69

GC content: 39.62

Gene sequence:

>4467_bases
ATGAACAACCCCACAGGACTAGAAATAGCAATAATTGGCATAAACGGTAAATTCCCCGGTGCTAATAACCTAGAAGAATA
TTGGCAAAACCTCCGCAACGGAGTAGAATCAATCACCAACTTAACCGACGAACAAATCCAAAAAAACGGCGTAGACCCCA
CACAATTAAAACATCCCAATTACGTCAAAAGACAAGCCATAATAGACAACATAGAATACTTTGACGCAGAATTTTTTGGC
TTTAACCCCAGAGAAGCAGAAATTCTCGACCCCCAGCACAGACTATTTTTAGAATGTGCTTGGACAGCCTTAGAAGACGC
AGGATATAACCCAGAAAACTACACCGGAGCAATTGGAGTTTATGCCGGTGCAGCCATGAATAACTATTTATTAAACCTAA
TTACAAACCCACAAATTCAAAATCAAATTAGCCGCTATCAACTATTTTTATCCAACGATAAAGACTTTCTCACCACCAGA
GTTTCTTATAAATTAAATTTACGAGGCCCAAGTTTAGATATTCAAACAGCTTGTTCCACATCCTTAGTAGCAGTTCATGT
AGCTTGTCAGAGTTTATTAAGTGGAGAATGCGACATAGCCCTAGCAGGGGGTGTATCCTTAGCAAAAGCCACAGGTTACT
TATATCAAGAAGGCGGAATTTACTCACCTGATGGTCATTGTCGCGCCTTTGATGCTGATGCTCAAGGAACAATTGCAGGT
AGTGGTTTAGGTATCGTTGTCCTTAAAAGACTGCAAGAAGCTATTGAAGATAGAGATTATATTCATGCTGTAATTAAAGG
TTCAGCTATTAATAATGATGGCGGTTTAAAAGTCAGTTACACAGCACCGAGAATTGATACCCAAGCAGCAGTAATTCGCG
CCGCACAAGCATTAGCTGGAGTAGAACCAGCAGATATTAGTTATATTGAAACCCACGGAACAGGAACAGCATTAGGAGAT
CCCATTGAAATTGCTGCTTTAACTCAAGCCTTCCGCGCCGGAACAGAAAAAACTGGATTTTGTGCCATATCATCAGTAAA
AACCAACATCGGACACTTAGATGCAGCAGCAGGAATTGCCAGTTTAATCAAAACAGTTTTAGCACTCAAACACCAACAAA
TTCCCCCCAATTTACATTTTCAACAACCAAATCCCCAAATAGATTTTTCCCAAACACCCTTTTATGTGAATACTAATTTA
GTTGACTGGGAAACAGATAAAACTCCCCGCCGTGCTGGTGTCAGTTCCTTTGGAATTGGGGGGACAAATGCTCATGTAAT
TTTAGAAGAAGCACCAATTAAATTCAAAATTCAAAATTCAAAATTCAAAATTAATTATCAGATGTTATGTTTATCGGCTA
AAAGTGAAAAAGCTCTTGAAGAAGCAACAATTAATCTGGCTACATATTTACAACAGCATCCACAATTCAACCTTGCAGAT
ATTGCTTATACCCTCCACATAGGACGACAACATTTTGCATATCGCCGGATGGTGTTGTGTCAAACCACAGAAGAAGCAGC
GCAAATTTTAGAGAAAGAAACTAAATACACTCATACAAATTCCGAAAAAAGCCCAAGTATCGCCTTCATGTTTCCCGGAC
AAGGTAGTCATTACCTCAACATGGGTAAGGAATTATATGAGACAGAAGCTATATTTCGAGAGCAAATAGATCATTGCTGT
GAATTATTACAGCATGATTTGGGGTTAGATTTGCTATCCATCCTATTTGAAACAGAAAGCATTCCCAGTCCCCAGTCCCC
AGTCCCCAGTCCCCAGTCCCAAACCATCTACGCACAACCAGCATTATTTATAATCGAATATGCCTTAGCAAAATTATGGA
TATCTTGGGGTATTCAACCACAGGCCATGATTGGTCATAGTCTCGGCGAATACGTAGTAGCCACTTTAGCAGGTGTCTTT
TCTCTCCCCGATGTTTTAAAATTAGTCGCATTGCGTGGTCGTTTAATGCAGCAATGTCCAACTGGTGCAATGCTCTCAGT
AGGAATGTCAGCAGCTAAACTACAACCTCTGTTGACAGATAATTTAGTCATAGCGGCATACAATGCACCAGAATTATGTG
TAGTATCTGGTACTGAAGCGGAAATCGTTCAACTAGAAACAAACTTAAATAAACAGGGAATTTCTAACCGTAGATTACAA
ACATCTCACGCTTTCCACTCACCCTTAATGGAGTCCATGATTACTCCATTTATCGCCGCTTTCCAGAAAATTACACTGCA
AACACCCAAAATTCCCTTTATTTCTAACGTTACAGGAACTTGGATTACAGCAGAACAAGCAACTGATCCGCACTACTGGG
TAAATCACTTACGTCAACCTGTACAATTTGCCACAGGAATCAAAGAACTGCTAACAGAACCTCAGCAAATTTTACTAGAA
GTAGGAGCAGGACGAACACTTGCTACCTTAGCCAAACAACAAACCAACAGCCATACAATTTTATCTTCCTTACGTCATCC
CCAAGATACACAATCAGATGTAGCATTTTTACTGCAAACCTTGGGTCAATTGTGGTTAGCAGGTGTATCAATTGATTGGG
AAAATTTCTACACACACCAACAACGTCAACGTTTACCATTACCCACCTATCCTTTTCAACGTCAGCGTTACTGGATTGAT
TTGAAAGCAGGAGAGCAGGGGAGCGAGAATATACCCAGTCCCCGGCTTTATCTTCCCTCTTGGGAACGTAGTTTACCTCA
TCCCCAAGTAGACATAGCTGAAAAACGCTTGTGTTGGTTGGTGTTTACAGATAATTACGGTATTTATCAAGAAATAATTA
ATACGCTACAAGCGGTTGGACATGATGTAATTATTGTGAGCCAAGGTGAAAAATACGACCAACCTGCATATCGTACTTTT
ACAGTTAATCCCCAAAACTCACAGGATTTTGTGGAATTGTGGTCAGATTTAGAACTGCGAGAACTCATTCCTCACCATAT
TTTATATTTATGGGATTTAACTGATTTACAACAGCAACCACTCAGTTTGTTGTATTTAGCGCAAGCAATTTCATCACAGT
CAATTGAGCGAGAAATAACATTAACTTTGGTAACAAATGATGGGCAATTGTTGTTAGGGAATGAAAATATTCAACCCATG
AAAGCGACAGTTTGGGGTATGGGTAAAGTGATTTCTCAAGAAATACCACAATTAACTTGTCGCTGTGTTGATATTTCATT
ATCCACTGTAGCTAGTACAAATGAACAAATCGCCCAACAATTAATTACAGAATGTTTAAATAATCAGAATGATTCTGTAG
TTGCTTATCGGGGTAATTATAGATGGAATCAAATTTATAAACCCTTATTAATGGACGATGCACAATCAAAAATATCTGTA
CATGAAGGAGGAAATTATGTAATTTTGGGAGACTTAACAACGGGTTTAGGAACAGTATTTGCTGAATTTCTGATGAAAAA
TTCAGTGCGATTAGTGCTACTTAGTGATGTCATTACCGAAACTCTCAAACAAAGTTTAGATAATGTTGGTATTGATTACT
TATCACTCAATATAGATATTACCAAGCAAGCAGAATTAGAAAATGCTATAGCTCAAGCCGAAACAAAATTCGGACAAATA
AATGGGGTATTTTACTCCACACCCATGAGCAATGAGCATTCAATGGCATTTTTACCCCAATTAACTACAAAACACTGGGA
ATATAACTACCGTACCAAAATCCAGGGCTTATGTGTTTTAGCTGAAGTTTTGCGGGATAAACCTTTAGATTTCTGTGTAT
TACAATCTTCCCTGTCCACAGTGTTAGGTGGGTTAGGTTTAGCCGTATACGCTGCGGCGAATGCAGTAATTGATATGTTT
GCTATCCAACAAAATCAAAATAGCAAATTCCCCTGGATTAGCATTAACTGGGATGCTTGTCGTAGCGACTTAGAAACAGA
TATTAATCATAGTTTCGCCGCCAATTTAGTAACATTAGCACTCACACCGGCAGAAGTATGGCAATCAACCCAACATATTA
TCAAATTGGGTTTACCAGAATCGGTTGTAGTTACAAAATCTGACTTAGACAAACGTTTAGAAAAGTGGGTAACAAACACC
CCAACCAAAACCAAAACAGAAACCAATAACAGCTACACCCGTCCCCAACTCACCAATGAATATATTGCACCCCGTGACGA
AATTGAAACAGCGATCGCCCAAATTTGGCAAGACCTATTAGGAATTTCCCCCATAGGAATTAATGATAGCTTCTTCGACT
TAGGCGGACACTCCCTACTAGCCATCCAAGCCATTTCCAGATTACGCGATCGCTTTGGTGTCGAACTCTCAATGCGAAAC
CTCCTCTACGAAGCACCCACAATCGCCGCAATCGCCACAATCATCACCACCCAAAACCAAAACCTAGAACAAATGACAGC
CCTACTCACAGAAATCCAAACCCTCACCCCAGAACAAATCCGCCAACAACTCAACCACCTCTCCTAA

Upstream 100 bases:

>100_bases
CTCCAACAAAGACAAACAAGACTAAAAACCTAACCCTCAAAAAAACTCTCCGCGCACCTTTGCGCTTACCTCTGCGCCCC
TCTGCGTTTAAAAAACCTAT

Downstream 100 bases:

>100_bases
AAACTCCGCGTACCTCCGCGCCTACCTCCGCGTACCTCTGCGTTAAAAAAAATGTCAAACTACTCACAAATCCTCTCAAC
CCTAACCCCAGAACAAAAAG

Product: polyketide synthase type I

Products: NA

Alternate protein names: 6-deoxyerythronolide B synthase I; DEBS 1; ORF 1 [H]

Number of amino acids: Translated: 1488; Mature: 1488

Protein sequence:

>1488_residues
MNNPTGLEIAIIGINGKFPGANNLEEYWQNLRNGVESITNLTDEQIQKNGVDPTQLKHPNYVKRQAIIDNIEYFDAEFFG
FNPREAEILDPQHRLFLECAWTALEDAGYNPENYTGAIGVYAGAAMNNYLLNLITNPQIQNQISRYQLFLSNDKDFLTTR
VSYKLNLRGPSLDIQTACSTSLVAVHVACQSLLSGECDIALAGGVSLAKATGYLYQEGGIYSPDGHCRAFDADAQGTIAG
SGLGIVVLKRLQEAIEDRDYIHAVIKGSAINNDGGLKVSYTAPRIDTQAAVIRAAQALAGVEPADISYIETHGTGTALGD
PIEIAALTQAFRAGTEKTGFCAISSVKTNIGHLDAAAGIASLIKTVLALKHQQIPPNLHFQQPNPQIDFSQTPFYVNTNL
VDWETDKTPRRAGVSSFGIGGTNAHVILEEAPIKFKIQNSKFKINYQMLCLSAKSEKALEEATINLATYLQQHPQFNLAD
IAYTLHIGRQHFAYRRMVLCQTTEEAAQILEKETKYTHTNSEKSPSIAFMFPGQGSHYLNMGKELYETEAIFREQIDHCC
ELLQHDLGLDLLSILFETESIPSPQSPVPSPQSQTIYAQPALFIIEYALAKLWISWGIQPQAMIGHSLGEYVVATLAGVF
SLPDVLKLVALRGRLMQQCPTGAMLSVGMSAAKLQPLLTDNLVIAAYNAPELCVVSGTEAEIVQLETNLNKQGISNRRLQ
TSHAFHSPLMESMITPFIAAFQKITLQTPKIPFISNVTGTWITAEQATDPHYWVNHLRQPVQFATGIKELLTEPQQILLE
VGAGRTLATLAKQQTNSHTILSSLRHPQDTQSDVAFLLQTLGQLWLAGVSIDWENFYTHQQRQRLPLPTYPFQRQRYWID
LKAGEQGSENIPSPRLYLPSWERSLPHPQVDIAEKRLCWLVFTDNYGIYQEIINTLQAVGHDVIIVSQGEKYDQPAYRTF
TVNPQNSQDFVELWSDLELRELIPHHILYLWDLTDLQQQPLSLLYLAQAISSQSIEREITLTLVTNDGQLLLGNENIQPM
KATVWGMGKVISQEIPQLTCRCVDISLSTVASTNEQIAQQLITECLNNQNDSVVAYRGNYRWNQIYKPLLMDDAQSKISV
HEGGNYVILGDLTTGLGTVFAEFLMKNSVRLVLLSDVITETLKQSLDNVGIDYLSLNIDITKQAELENAIAQAETKFGQI
NGVFYSTPMSNEHSMAFLPQLTTKHWEYNYRTKIQGLCVLAEVLRDKPLDFCVLQSSLSTVLGGLGLAVYAAANAVIDMF
AIQQNQNSKFPWISINWDACRSDLETDINHSFAANLVTLALTPAEVWQSTQHIIKLGLPESVVVTKSDLDKRLEKWVTNT
PTKTKTETNNSYTRPQLTNEYIAPRDEIETAIAQIWQDLLGISPIGINDSFFDLGGHSLLAIQAISRLRDRFGVELSMRN
LLYEAPTIAAIATIITTQNQNLEQMTALLTEIQTLTPEQIRQQLNHLS

Sequences:

>Translated_1488_residues
MNNPTGLEIAIIGINGKFPGANNLEEYWQNLRNGVESITNLTDEQIQKNGVDPTQLKHPNYVKRQAIIDNIEYFDAEFFG
FNPREAEILDPQHRLFLECAWTALEDAGYNPENYTGAIGVYAGAAMNNYLLNLITNPQIQNQISRYQLFLSNDKDFLTTR
VSYKLNLRGPSLDIQTACSTSLVAVHVACQSLLSGECDIALAGGVSLAKATGYLYQEGGIYSPDGHCRAFDADAQGTIAG
SGLGIVVLKRLQEAIEDRDYIHAVIKGSAINNDGGLKVSYTAPRIDTQAAVIRAAQALAGVEPADISYIETHGTGTALGD
PIEIAALTQAFRAGTEKTGFCAISSVKTNIGHLDAAAGIASLIKTVLALKHQQIPPNLHFQQPNPQIDFSQTPFYVNTNL
VDWETDKTPRRAGVSSFGIGGTNAHVILEEAPIKFKIQNSKFKINYQMLCLSAKSEKALEEATINLATYLQQHPQFNLAD
IAYTLHIGRQHFAYRRMVLCQTTEEAAQILEKETKYTHTNSEKSPSIAFMFPGQGSHYLNMGKELYETEAIFREQIDHCC
ELLQHDLGLDLLSILFETESIPSPQSPVPSPQSQTIYAQPALFIIEYALAKLWISWGIQPQAMIGHSLGEYVVATLAGVF
SLPDVLKLVALRGRLMQQCPTGAMLSVGMSAAKLQPLLTDNLVIAAYNAPELCVVSGTEAEIVQLETNLNKQGISNRRLQ
TSHAFHSPLMESMITPFIAAFQKITLQTPKIPFISNVTGTWITAEQATDPHYWVNHLRQPVQFATGIKELLTEPQQILLE
VGAGRTLATLAKQQTNSHTILSSLRHPQDTQSDVAFLLQTLGQLWLAGVSIDWENFYTHQQRQRLPLPTYPFQRQRYWID
LKAGEQGSENIPSPRLYLPSWERSLPHPQVDIAEKRLCWLVFTDNYGIYQEIINTLQAVGHDVIIVSQGEKYDQPAYRTF
TVNPQNSQDFVELWSDLELRELIPHHILYLWDLTDLQQQPLSLLYLAQAISSQSIEREITLTLVTNDGQLLLGNENIQPM
KATVWGMGKVISQEIPQLTCRCVDISLSTVASTNEQIAQQLITECLNNQNDSVVAYRGNYRWNQIYKPLLMDDAQSKISV
HEGGNYVILGDLTTGLGTVFAEFLMKNSVRLVLLSDVITETLKQSLDNVGIDYLSLNIDITKQAELENAIAQAETKFGQI
NGVFYSTPMSNEHSMAFLPQLTTKHWEYNYRTKIQGLCVLAEVLRDKPLDFCVLQSSLSTVLGGLGLAVYAAANAVIDMF
AIQQNQNSKFPWISINWDACRSDLETDINHSFAANLVTLALTPAEVWQSTQHIIKLGLPESVVVTKSDLDKRLEKWVTNT
PTKTKTETNNSYTRPQLTNEYIAPRDEIETAIAQIWQDLLGISPIGINDSFFDLGGHSLLAIQAISRLRDRFGVELSMRN
LLYEAPTIAAIATIITTQNQNLEQMTALLTEIQTLTPEQIRQQLNHLS
>Mature_1488_residues
MNNPTGLEIAIIGINGKFPGANNLEEYWQNLRNGVESITNLTDEQIQKNGVDPTQLKHPNYVKRQAIIDNIEYFDAEFFG
FNPREAEILDPQHRLFLECAWTALEDAGYNPENYTGAIGVYAGAAMNNYLLNLITNPQIQNQISRYQLFLSNDKDFLTTR
VSYKLNLRGPSLDIQTACSTSLVAVHVACQSLLSGECDIALAGGVSLAKATGYLYQEGGIYSPDGHCRAFDADAQGTIAG
SGLGIVVLKRLQEAIEDRDYIHAVIKGSAINNDGGLKVSYTAPRIDTQAAVIRAAQALAGVEPADISYIETHGTGTALGD
PIEIAALTQAFRAGTEKTGFCAISSVKTNIGHLDAAAGIASLIKTVLALKHQQIPPNLHFQQPNPQIDFSQTPFYVNTNL
VDWETDKTPRRAGVSSFGIGGTNAHVILEEAPIKFKIQNSKFKINYQMLCLSAKSEKALEEATINLATYLQQHPQFNLAD
IAYTLHIGRQHFAYRRMVLCQTTEEAAQILEKETKYTHTNSEKSPSIAFMFPGQGSHYLNMGKELYETEAIFREQIDHCC
ELLQHDLGLDLLSILFETESIPSPQSPVPSPQSQTIYAQPALFIIEYALAKLWISWGIQPQAMIGHSLGEYVVATLAGVF
SLPDVLKLVALRGRLMQQCPTGAMLSVGMSAAKLQPLLTDNLVIAAYNAPELCVVSGTEAEIVQLETNLNKQGISNRRLQ
TSHAFHSPLMESMITPFIAAFQKITLQTPKIPFISNVTGTWITAEQATDPHYWVNHLRQPVQFATGIKELLTEPQQILLE
VGAGRTLATLAKQQTNSHTILSSLRHPQDTQSDVAFLLQTLGQLWLAGVSIDWENFYTHQQRQRLPLPTYPFQRQRYWID
LKAGEQGSENIPSPRLYLPSWERSLPHPQVDIAEKRLCWLVFTDNYGIYQEIINTLQAVGHDVIIVSQGEKYDQPAYRTF
TVNPQNSQDFVELWSDLELRELIPHHILYLWDLTDLQQQPLSLLYLAQAISSQSIEREITLTLVTNDGQLLLGNENIQPM
KATVWGMGKVISQEIPQLTCRCVDISLSTVASTNEQIAQQLITECLNNQNDSVVAYRGNYRWNQIYKPLLMDDAQSKISV
HEGGNYVILGDLTTGLGTVFAEFLMKNSVRLVLLSDVITETLKQSLDNVGIDYLSLNIDITKQAELENAIAQAETKFGQI
NGVFYSTPMSNEHSMAFLPQLTTKHWEYNYRTKIQGLCVLAEVLRDKPLDFCVLQSSLSTVLGGLGLAVYAAANAVIDMF
AIQQNQNSKFPWISINWDACRSDLETDINHSFAANLVTLALTPAEVWQSTQHIIKLGLPESVVVTKSDLDKRLEKWVTNT
PTKTKTETNNSYTRPQLTNEYIAPRDEIETAIAQIWQDLLGISPIGINDSFFDLGGHSLLAIQAISRLRDRFGVELSMRN
LLYEAPTIAAIATIITTQNQNLEQMTALLTEIQTLTPEQIRQQLNHLS

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Specific For Elongation From C-10 To Unsaturated C-16 And C-18 Fatty Acids. [C]

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=864, Percent_Identity=28.8194444444444, Blast_Score=320, Evalue=8e-87,
Organism=Homo sapiens, GI8923559, Length=445, Percent_Identity=26.2921348314607, Blast_Score=134, Evalue=1e-30,
Organism=Homo sapiens, GI223972627, Length=151, Percent_Identity=37.7483443708609, Blast_Score=84, Evalue=9e-16,
Organism=Homo sapiens, GI51243059, Length=345, Percent_Identity=26.0869565217391, Blast_Score=78, Evalue=5e-14,
Organism=Escherichia coli, GI1788663, Length=428, Percent_Identity=25, Blast_Score=104, Evalue=3e-23,
Organism=Escherichia coli, GI1787337, Length=275, Percent_Identity=28, Blast_Score=97, Evalue=6e-21,
Organism=Escherichia coli, GI1787334, Length=313, Percent_Identity=28.7539936102236, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17550940, Length=921, Percent_Identity=30.0760043431053, Blast_Score=361, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI212642053, Length=919, Percent_Identity=26.8770402611534, Blast_Score=282, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI71983535, Length=271, Percent_Identity=29.8892988929889, Blast_Score=94, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71983541, Length=277, Percent_Identity=30.3249097472924, Blast_Score=93, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71984332, Length=308, Percent_Identity=26.9480519480519, Blast_Score=91, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6320904, Length=456, Percent_Identity=26.0964912280702, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI221330659, Length=871, Percent_Identity=28.4730195177956, Blast_Score=307, Evalue=3e-83,
Organism=Drosophila melanogaster, GI19920632, Length=871, Percent_Identity=28.4730195177956, Blast_Score=306, Evalue=5e-83,
Organism=Drosophila melanogaster, GI24581345, Length=874, Percent_Identity=27.8032036613272, Blast_Score=283, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24644341, Length=449, Percent_Identity=25.3897550111359, Blast_Score=110, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24665753, Length=367, Percent_Identity=27.7929155313352, Blast_Score=83, Evalue=2e-15,

Paralogues:

None

Copy number: 24024 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 30,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR013968
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.94 [H]

Molecular weight: Translated: 165549; Mature: 165549

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNPTGLEIAIIGINGKFPGANNLEEYWQNLRNGVESITNLTDEQIQKNGVDPTQLKHPN
CCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHCCCCC
YVKRQAIIDNIEYFDAEFFGFNPREAEILDPQHRLFLECAWTALEDAGYNPENYTGAIGV
HHHHHHHHHHHHHHCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHH
YAGAAMNNYLLNLITNPQIQNQISRYQLFLSNDKDFLTTRVSYKLNLRGPSLDIQTACST
HHHHHHHHHHHHECCCCHHHHHHHHEEEEECCCCCEEEEEEEEEEEECCCCCCHHHHCCH
SLVAVHVACQSLLSGECDIALAGGVSLAKATGYLYQEGGIYSPDGHCRAFDADAQGTIAG
HHHHHHHHHHHHHCCCCCEEEECCCHHHHHHCEEEECCCEECCCCCEEEECCCCCCCEEC
SGLGIVVLKRLQEAIEDRDYIHAVIKGSAINNDGGLKVSYTAPRIDTQAAVIRAAQALAG
CCHHHHHHHHHHHHHHHHHHEEHEEECCEECCCCCEEEEEECCCCCHHHHHHHHHHHHHC
VEPADISYIETHGTGTALGDPIEIAALTQAFRAGTEKTGFCAISSVKTNIGHLDAAAGIA
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCHHHHHHHHH
SLIKTVLALKHQQIPPNLHFQQPNPQIDFSQTPFYVNTNLVDWETDKTPRRAGVSSFGIG
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCEEECCCCCCHHHCCCCCCCCC
GTNAHVILEEAPIKFKIQNSKFKINYQMLCLSAKSEKALEEATINLATYLQQHPQFNLAD
CCCCEEEEECCCEEEEEECCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHH
IAYTLHIGRQHFAYRRMVLCQTTEEAAQILEKETKYTHTNSEKSPSIAFMFPGQGSHYLN
EEEEEHHCHHHHHHHHHHHEECHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHH
MGKELYETEAIFREQIDHCCELLQHDLGLDLLSILFETESIPSPQSPVPSPQSQTIYAQP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECH
ALFIIEYALAKLWISWGIQPQAMIGHSLGEYVVATLAGVFSLPDVLKLVALRGRLMQQCP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
TGAMLSVGMSAAKLQPLLTDNLVIAAYNAPELCVVSGTEAEIVQLETNLNKQGISNRRLQ
CCHHHHCCCHHHHCCHHCCCCEEEEEECCCCEEEEECCCCEEEEEECCCCCCCCCCCCEE
TSHAFHSPLMESMITPFIAAFQKITLQTPKIPFISNVTGTWITAEQATDPHYWVNHLRQP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
VQFATGIKELLTEPQQILLEVGAGRTLATLAKQQTNSHTILSSLRHPQDTQSDVAFLLQT
HHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHH
LGQLWLAGVSIDWENFYTHQQRQRLPLPTYPFQRQRYWIDLKAGEQGSENIPSPRLYLPS
HHHHHHHCCEECHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEECCC
WERSLPHPQVDIAEKRLCWLVFTDNYGIYQEIINTLQAVGHDVIIVSQGEKYDQPAYRTF
HHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEE
TVNPQNSQDFVELWSDLELRELIPHHILYLWDLTDLQQQPLSLLYLAQAISSQSIEREIT
EECCCCCHHHHHHHCCCCHHHHCHHHEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LTLVTNDGQLLLGNENIQPMKATVWGMGKVISQEIPQLTCRCVDISLSTVASTNEQIAQQ
EEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHCCHHHHHHH
LITECLNNQNDSVVAYRGNYRWNQIYKPLLMDDAQSKISVHEGGNYVILGDLTTGLGTVF
HHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCEEEEECCHHHHHHHH
AEFLMKNSVRLVLLSDVITETLKQSLDNVGIDYLSLNIDITKQAELENAIAQAETKFGQI
HHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHHHCC
NGVFYSTPMSNEHSMAFLPQLTTKHWEYNYRTKIQGLCVLAEVLRDKPLDFCVLQSSLST
CCEEEECCCCCCCCEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VLGGLGLAVYAAANAVIDMFAIQQNQNSKFPWISINWDACRSDLETDINHSFAANLVTLA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHCCCHHHHHCEEEEE
LTPAEVWQSTQHIIKLGLPESVVVTKSDLDKRLEKWVTNTPTKTKTETNNSYTRPQLTNE
ECHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
YIAPRDEIETAIAQIWQDLLGISPIGINDSFFDLGGHSLLAIQAISRLRDRFGVELSMRN
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHCCEEEHHH
LLYEAPTIAAIATIITTQNQNLEQMTALLTEIQTLTPEQIRQQLNHLS
HHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MNNPTGLEIAIIGINGKFPGANNLEEYWQNLRNGVESITNLTDEQIQKNGVDPTQLKHPN
CCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHCCCCC
YVKRQAIIDNIEYFDAEFFGFNPREAEILDPQHRLFLECAWTALEDAGYNPENYTGAIGV
HHHHHHHHHHHHHHCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHH
YAGAAMNNYLLNLITNPQIQNQISRYQLFLSNDKDFLTTRVSYKLNLRGPSLDIQTACST
HHHHHHHHHHHHECCCCHHHHHHHHEEEEECCCCCEEEEEEEEEEEECCCCCCHHHHCCH
SLVAVHVACQSLLSGECDIALAGGVSLAKATGYLYQEGGIYSPDGHCRAFDADAQGTIAG
HHHHHHHHHHHHHCCCCCEEEECCCHHHHHHCEEEECCCEECCCCCEEEECCCCCCCEEC
SGLGIVVLKRLQEAIEDRDYIHAVIKGSAINNDGGLKVSYTAPRIDTQAAVIRAAQALAG
CCHHHHHHHHHHHHHHHHHHEEHEEECCEECCCCCEEEEEECCCCCHHHHHHHHHHHHHC
VEPADISYIETHGTGTALGDPIEIAALTQAFRAGTEKTGFCAISSVKTNIGHLDAAAGIA
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCHHHHHHHHH
SLIKTVLALKHQQIPPNLHFQQPNPQIDFSQTPFYVNTNLVDWETDKTPRRAGVSSFGIG
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCEEECCCCCCHHHCCCCCCCCC
GTNAHVILEEAPIKFKIQNSKFKINYQMLCLSAKSEKALEEATINLATYLQQHPQFNLAD
CCCCEEEEECCCEEEEEECCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHH
IAYTLHIGRQHFAYRRMVLCQTTEEAAQILEKETKYTHTNSEKSPSIAFMFPGQGSHYLN
EEEEEHHCHHHHHHHHHHHEECHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHH
MGKELYETEAIFREQIDHCCELLQHDLGLDLLSILFETESIPSPQSPVPSPQSQTIYAQP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECH
ALFIIEYALAKLWISWGIQPQAMIGHSLGEYVVATLAGVFSLPDVLKLVALRGRLMQQCP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
TGAMLSVGMSAAKLQPLLTDNLVIAAYNAPELCVVSGTEAEIVQLETNLNKQGISNRRLQ
CCHHHHCCCHHHHCCHHCCCCEEEEEECCCCEEEEECCCCEEEEEECCCCCCCCCCCCEE
TSHAFHSPLMESMITPFIAAFQKITLQTPKIPFISNVTGTWITAEQATDPHYWVNHLRQP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
VQFATGIKELLTEPQQILLEVGAGRTLATLAKQQTNSHTILSSLRHPQDTQSDVAFLLQT
HHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHH
LGQLWLAGVSIDWENFYTHQQRQRLPLPTYPFQRQRYWIDLKAGEQGSENIPSPRLYLPS
HHHHHHHCCEECHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEECCC
WERSLPHPQVDIAEKRLCWLVFTDNYGIYQEIINTLQAVGHDVIIVSQGEKYDQPAYRTF
HHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEE
TVNPQNSQDFVELWSDLELRELIPHHILYLWDLTDLQQQPLSLLYLAQAISSQSIEREIT
EECCCCCHHHHHHHCCCCHHHHCHHHEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LTLVTNDGQLLLGNENIQPMKATVWGMGKVISQEIPQLTCRCVDISLSTVASTNEQIAQQ
EEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHCCHHHHHHH
LITECLNNQNDSVVAYRGNYRWNQIYKPLLMDDAQSKISVHEGGNYVILGDLTTGLGTVF
HHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCEEEEECCHHHHHHHH
AEFLMKNSVRLVLLSDVITETLKQSLDNVGIDYLSLNIDITKQAELENAIAQAETKFGQI
HHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHHHCC
NGVFYSTPMSNEHSMAFLPQLTTKHWEYNYRTKIQGLCVLAEVLRDKPLDFCVLQSSLST
CCEEEECCCCCCCCEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VLGGLGLAVYAAANAVIDMFAIQQNQNSKFPWISINWDACRSDLETDINHSFAANLVTLA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHCCCHHHHHCEEEEE
LTPAEVWQSTQHIIKLGLPESVVVTKSDLDKRLEKWVTNTPTKTKTETNNSYTRPQLTNE
ECHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
YIAPRDEIETAIAQIWQDLLGISPIGINDSFFDLGGHSLLAIQAISRLRDRFGVELSMRN
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHCCEEEHHH
LLYEAPTIAAIATIITTQNQNLEQMTALLTEIQTLTPEQIRQQLNHLS
HHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2024119; 8386127 [H]