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The map label for this gene is lgrC [H]

Identifier: 17230139

GI number: 17230139

Start: 3186891

End: 3190151

Strand: Reverse

Name: lgrC [H]

Synonym: all2647

Alternate gene names: 17230139

Gene position: 3190151-3186891 (Counterclockwise)

Preceding gene: 17230140

Following gene: 17230138

Centisome position: 49.74

GC content: 41.31

Gene sequence:

>3261_bases
ATGAATACAACTCTAAATCAAAAAATGATTGAGGATATTTATCCCCTCTCATCTTTGCAGCAGGGTATGTTATTTCATAG
TCTGTATGCGCCTAACTCTGGTGCTTATGTGGTACAGGTAAGTTATGAGTTACATGGTAATTTAAATATTGCGGCTTTTG
AGGCTGCTTGGCAAGATTTAATCAATCGTCATCCTGTTTTACGCACAGCTTTTGTTTGGGATAATTTAGAAAAGCCGCTA
CAAGTAGTTGGGAAGCAAGTAAAATGTCAGATTAATCATCTTGATTGGAGTGATGTTTCAGTTCAGCAACAACAGGAAGC
TTTAAAAGTTCTGCTGCTACAAAAACAGCGCGAACAGGGATTTAATTTATCCCAAGCACCTCTGATGCAAATGACACTCA
TTCAGTTAAAATCTGAAGTTTATCAGTTTGTTTGGAGTTATCACCATTTATTATTAGATGGTTGGTCTGTTCAGGTACTT
TTAAAAGAATTTATTGTTATTTATCAAGCATATATTCAACAACAAACACCTGTTTTACTCAACCCACGTCGCTATCGAGA
TTATATTGGGTGGTTACAGCAACAAAACTTGGCGGAAGCTGAGACTTTTTGGAAACAGCAATTACAGGGGTTTGTGTCGC
CAACGCAGTTAAATGTTGGTCAAAACCTAGATGTTCGTCCCGATAATTTACATAGTCATTATCACGAGGAAAAAATTCAG
CTTTCAGTCGAATTAACTAGCAAACTGCAAACCCTAGCCAAACAACAACAATTAACCATCAATACCTTTGTCCAAGGTGC
TTGGGCGTTGTTGTTAAGTCGCTATAGTGGGGAAAAAAATGTTTTATTTGCTACCGTTAGTGCAGGTCGTCCCAGTGCGC
TGAATGGTGCTGATGCAATGGTGGGATTATTTATCAATACCTTACCATTCCGGGTGTTAGTTTCTCCTGAAGAGACACTA
TATCAATGGTTGCAAAAGCTACAAAATCAGCAAGTAGAAATACGGCAATATGAATATAGTTCTTTAGTAGATATTCATCG
TTGGAGTCAAGTTTCACCATCCATACCACTATTTGAAACCTTGGTGGTATTTGAAAATTATCCCATTGAACCTGCTCTGA
AACAGTCTTTAGCATCTTTGGAAATTCGCAATATTCAAGCTACGGAACAGACGAATTATCCTCTGACGCTGTATGCAGTG
GTGGATTCTCAGCTTGCTTTGAGAATTTTATATGATAGCGATCGCTTTCACCATACCACCATCACCCAAATCTTAGAACA
GTTAGAAACCCTGTTGTTAGGAATGACACAGGGAGATTGTAATTTAGCCACACTCCCATTTCTCAGTCCCACCCAACAAC
AGCAAATACTCATTGACTGGAACGCCACAACACAGGAAATTCCTCAGCAATGTGTTCATGAAATCATCAGCCAGCAAGCA
CAACAAACACCGGACGCGACAGCAGTTGTATTTGCAGATAAAACCCTAACTTATGCCGAATTAAACGCCAAATCCAACCA
AATCGCCCATTATCTACTACAACTAGGAATCAAACCAGAAGCCAGAATTGGGGTTTATTTAGAGCGTTCATCGCCATTAT
TAATCATAGCCCTACTGGGTATCCTCAAAGCTGGTGCAGCCTACGTACCACTAGACCCCACCTTCCCCCCAGAACGTCTG
CGTTTCATGATGGCAGATGCAGAGTTAAAATTGTTGCTTACACAAACATCTTTAACTAGTGTTATTACTGACAAAATAGC
AACAATTAACCTCGATGAATTAGAGGAAGATATTAGCCAGCAGCCAATATTTGACCCACAAATTAAAGTAACACCAGAAC
AACTAACTTATTTAATTTATACATCTGGGTCAACAGGGCAACCAAAAGGGGTGATGATTGAAGGGCGATCGCTCGTTAAC
ATCTTAACAGACCTGAAACAACGTTTATCAATCACCCCTAACGACAAACTCCTAGCAGTCACCACCATCGCCTTTGACAT
CGCCGCCTTAGAATTATTTCTCCCCTTAATTGCAGGCGCACAAGTCGTATTACCCCCCCAAACAGCCTTAGTTGACCCTC
GCCAACTCGCCAACTGCATAGAACACCATCAAATTACCATCATGCAAGCCACCCCCGCAACTTGGCGGTTACTTCTAGCC
AGTGGTTGGGAAGGGAAACAGGACTTAAAAATCCTCTGTGGTGGCGAAGCACTAGAGAATACCCTAGCCCAACAGTTATT
ATCTTGCAGTCAAGAAGTCTGGAATCTATACGGCCCAACAGAAACCACAATTTGGTCAGCAGCCCAGAAACTAAGTATAG
ATGAACCCGTAACCATCGGTCATCCCATCGCCAACACACAATTTTACATCCTCGACGAACAGTTACAACCCGTCCCCATC
GGCGTACCAGGAGAATTATATATTGGTGGTGCAGGAGTCGCCAGAGGATATTGGAAACGCCCAGACTTAACAGCAGAGAG
ATTTAAGGGACTGGGGACTGGGCAGAGAAATTACCCTACTCCCTACTCCCTACTCCCTACTCCCTTATACAAAACAGGCG
ATCGCGTCCGCTACCTAAGAGATGGTAAACTCGAATACTTAGGGAGACTAGATTATCAAATCAAAATTCGCGGATTTCGC
ATCGAACTAGGAGAAATAGAAGCGGTACTAGCACAACATCCCGCAGTAGAACAAGCAGTAGTCACCCTGCGAGAAGATGA
ACCAGGAGAACAGCGTTTAGTAGCCTATATAGTCTCCCACCCTGAAATTATCCCCACAGAACTACGCACATTTTTAGGTG
AAAAACTACCTATATATATGATGCCATCGGCATTCATATTATTAGAAAAATTCCCCCTCACACCCAACGGTAAAATAGAC
CGCAAAGCATTACCAAAATCCAACAATTTACCTTTAACAACCACTAATAATTTCATACCACCGCAAACCCAAATCGAACA
AACCCTGTCTGATATTTGGCAACAATTATTAGGTAGAGAAAAAATCAGCATTCATGATAACTTCTTCGACTTAGGAGGAC
ATTCATTATTAATAGTAAGAATGCAAGGACAACTCACCCTAAAACTCAATCAAAACATACCCCTAGTAGACCTATTCCGT
TATCCCACCATCAACTCCCTAGCAAAATACCTAACCCAAAACACCCCCACATCAGATAAAGAAATAGAAAACAGAATCTC
CCAACAACAAACCGGAAAACAAAGACTCCTCCAACAAAGACAAACAAGACTAAAAACCTAA

Upstream 100 bases:

>100_bases
TGGGAGGTTACACACCTTCTGATTTTGAGTTAGCAAATTTAAATCAAGAAACTTTAGATTTGGTGATGGGGATGATTAGT
TTTGCACCGGAGGGTTTGCA

Downstream 100 bases:

>100_bases
CCCTCAAAAAAACTCTCCGCGCACCTTTGCGCTTACCTCTGCGCCCCTCTGCGTTTAAAAAACCTATATGAACAACCCCA
CAGGACTAGAAATAGCAATA

Product: microcystin synthetase B

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1086; Mature: 1086

Protein sequence:

>1086_residues
MNTTLNQKMIEDIYPLSSLQQGMLFHSLYAPNSGAYVVQVSYELHGNLNIAAFEAAWQDLINRHPVLRTAFVWDNLEKPL
QVVGKQVKCQINHLDWSDVSVQQQQEALKVLLLQKQREQGFNLSQAPLMQMTLIQLKSEVYQFVWSYHHLLLDGWSVQVL
LKEFIVIYQAYIQQQTPVLLNPRRYRDYIGWLQQQNLAEAETFWKQQLQGFVSPTQLNVGQNLDVRPDNLHSHYHEEKIQ
LSVELTSKLQTLAKQQQLTINTFVQGAWALLLSRYSGEKNVLFATVSAGRPSALNGADAMVGLFINTLPFRVLVSPEETL
YQWLQKLQNQQVEIRQYEYSSLVDIHRWSQVSPSIPLFETLVVFENYPIEPALKQSLASLEIRNIQATEQTNYPLTLYAV
VDSQLALRILYDSDRFHHTTITQILEQLETLLLGMTQGDCNLATLPFLSPTQQQQILIDWNATTQEIPQQCVHEIISQQA
QQTPDATAVVFADKTLTYAELNAKSNQIAHYLLQLGIKPEARIGVYLERSSPLLIIALLGILKAGAAYVPLDPTFPPERL
RFMMADAELKLLLTQTSLTSVITDKIATINLDELEEDISQQPIFDPQIKVTPEQLTYLIYTSGSTGQPKGVMIEGRSLVN
ILTDLKQRLSITPNDKLLAVTTIAFDIAALELFLPLIAGAQVVLPPQTALVDPRQLANCIEHHQITIMQATPATWRLLLA
SGWEGKQDLKILCGGEALENTLAQQLLSCSQEVWNLYGPTETTIWSAAQKLSIDEPVTIGHPIANTQFYILDEQLQPVPI
GVPGELYIGGAGVARGYWKRPDLTAERFKGLGTGQRNYPTPYSLLPTPLYKTGDRVRYLRDGKLEYLGRLDYQIKIRGFR
IELGEIEAVLAQHPAVEQAVVTLREDEPGEQRLVAYIVSHPEIIPTELRTFLGEKLPIYMMPSAFILLEKFPLTPNGKID
RKALPKSNNLPLTTTNNFIPPQTQIEQTLSDIWQQLLGREKISIHDNFFDLGGHSLLIVRMQGQLTLKLNQNIPLVDLFR
YPTINSLAKYLTQNTPTSDKEIENRISQQQTGKQRLLQQRQTRLKT

Sequences:

>Translated_1086_residues
MNTTLNQKMIEDIYPLSSLQQGMLFHSLYAPNSGAYVVQVSYELHGNLNIAAFEAAWQDLINRHPVLRTAFVWDNLEKPL
QVVGKQVKCQINHLDWSDVSVQQQQEALKVLLLQKQREQGFNLSQAPLMQMTLIQLKSEVYQFVWSYHHLLLDGWSVQVL
LKEFIVIYQAYIQQQTPVLLNPRRYRDYIGWLQQQNLAEAETFWKQQLQGFVSPTQLNVGQNLDVRPDNLHSHYHEEKIQ
LSVELTSKLQTLAKQQQLTINTFVQGAWALLLSRYSGEKNVLFATVSAGRPSALNGADAMVGLFINTLPFRVLVSPEETL
YQWLQKLQNQQVEIRQYEYSSLVDIHRWSQVSPSIPLFETLVVFENYPIEPALKQSLASLEIRNIQATEQTNYPLTLYAV
VDSQLALRILYDSDRFHHTTITQILEQLETLLLGMTQGDCNLATLPFLSPTQQQQILIDWNATTQEIPQQCVHEIISQQA
QQTPDATAVVFADKTLTYAELNAKSNQIAHYLLQLGIKPEARIGVYLERSSPLLIIALLGILKAGAAYVPLDPTFPPERL
RFMMADAELKLLLTQTSLTSVITDKIATINLDELEEDISQQPIFDPQIKVTPEQLTYLIYTSGSTGQPKGVMIEGRSLVN
ILTDLKQRLSITPNDKLLAVTTIAFDIAALELFLPLIAGAQVVLPPQTALVDPRQLANCIEHHQITIMQATPATWRLLLA
SGWEGKQDLKILCGGEALENTLAQQLLSCSQEVWNLYGPTETTIWSAAQKLSIDEPVTIGHPIANTQFYILDEQLQPVPI
GVPGELYIGGAGVARGYWKRPDLTAERFKGLGTGQRNYPTPYSLLPTPLYKTGDRVRYLRDGKLEYLGRLDYQIKIRGFR
IELGEIEAVLAQHPAVEQAVVTLREDEPGEQRLVAYIVSHPEIIPTELRTFLGEKLPIYMMPSAFILLEKFPLTPNGKID
RKALPKSNNLPLTTTNNFIPPQTQIEQTLSDIWQQLLGREKISIHDNFFDLGGHSLLIVRMQGQLTLKLNQNIPLVDLFR
YPTINSLAKYLTQNTPTSDKEIENRISQQQTGKQRLLQQRQTRLKT
>Mature_1086_residues
MNTTLNQKMIEDIYPLSSLQQGMLFHSLYAPNSGAYVVQVSYELHGNLNIAAFEAAWQDLINRHPVLRTAFVWDNLEKPL
QVVGKQVKCQINHLDWSDVSVQQQQEALKVLLLQKQREQGFNLSQAPLMQMTLIQLKSEVYQFVWSYHHLLLDGWSVQVL
LKEFIVIYQAYIQQQTPVLLNPRRYRDYIGWLQQQNLAEAETFWKQQLQGFVSPTQLNVGQNLDVRPDNLHSHYHEEKIQ
LSVELTSKLQTLAKQQQLTINTFVQGAWALLLSRYSGEKNVLFATVSAGRPSALNGADAMVGLFINTLPFRVLVSPEETL
YQWLQKLQNQQVEIRQYEYSSLVDIHRWSQVSPSIPLFETLVVFENYPIEPALKQSLASLEIRNIQATEQTNYPLTLYAV
VDSQLALRILYDSDRFHHTTITQILEQLETLLLGMTQGDCNLATLPFLSPTQQQQILIDWNATTQEIPQQCVHEIISQQA
QQTPDATAVVFADKTLTYAELNAKSNQIAHYLLQLGIKPEARIGVYLERSSPLLIIALLGILKAGAAYVPLDPTFPPERL
RFMMADAELKLLLTQTSLTSVITDKIATINLDELEEDISQQPIFDPQIKVTPEQLTYLIYTSGSTGQPKGVMIEGRSLVN
ILTDLKQRLSITPNDKLLAVTTIAFDIAALELFLPLIAGAQVVLPPQTALVDPRQLANCIEHHQITIMQATPATWRLLLA
SGWEGKQDLKILCGGEALENTLAQQLLSCSQEVWNLYGPTETTIWSAAQKLSIDEPVTIGHPIANTQFYILDEQLQPVPI
GVPGELYIGGAGVARGYWKRPDLTAERFKGLGTGQRNYPTPYSLLPTPLYKTGDRVRYLRDGKLEYLGRLDYQIKIRGFR
IELGEIEAVLAQHPAVEQAVVTLREDEPGEQRLVAYIVSHPEIIPTELRTFLGEKLPIYMMPSAFILLEKFPLTPNGKID
RKALPKSNNLPLTTTNNFIPPQTQIEQTLSDIWQQLLGREKISIHDNFFDLGGHSLLIVRMQGQLTLKLNQNIPLVDLFR
YPTINSLAKYLTQNTPTSDKEIENRISQQQTGKQRLLQQRQTRLKT

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=685, Percent_Identity=23.6496350364963, Blast_Score=141, Evalue=3e-33,
Organism=Homo sapiens, GI187761345, Length=549, Percent_Identity=24.9544626593807, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI187761343, Length=549, Percent_Identity=24.9544626593807, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI38505220, Length=568, Percent_Identity=22.1830985915493, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI156151445, Length=566, Percent_Identity=22.0848056537102, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI157311624, Length=527, Percent_Identity=23.719165085389, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI157311622, Length=527, Percent_Identity=23.719165085389, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI42544132, Length=504, Percent_Identity=21.2301587301587, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI58082049, Length=523, Percent_Identity=23.3269598470363, Blast_Score=81, Evalue=5e-15,
Organism=Homo sapiens, GI122937307, Length=367, Percent_Identity=26.158038147139, Blast_Score=79, Evalue=3e-14,
Organism=Escherichia coli, GI1786801, Length=1088, Percent_Identity=29.2279411764706, Blast_Score=333, Evalue=3e-92,
Organism=Escherichia coli, GI145693145, Length=525, Percent_Identity=26.2857142857143, Blast_Score=128, Evalue=2e-30,
Organism=Escherichia coli, GI1788107, Length=558, Percent_Identity=25.2688172043011, Blast_Score=120, Evalue=5e-28,
Organism=Escherichia coli, GI1786810, Length=533, Percent_Identity=26.078799249531, Blast_Score=114, Evalue=4e-26,
Organism=Escherichia coli, GI1790505, Length=570, Percent_Identity=23.859649122807, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1789201, Length=370, Percent_Identity=23.7837837837838, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17556356, Length=516, Percent_Identity=28.8759689922481, Blast_Score=164, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17550940, Length=952, Percent_Identity=21.6386554621849, Blast_Score=146, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI32564420, Length=446, Percent_Identity=24.8878923766816, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32564422, Length=446, Percent_Identity=24.8878923766816, Blast_Score=100, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI32563687, Length=514, Percent_Identity=22.3735408560311, Blast_Score=94, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17538037, Length=554, Percent_Identity=23.1046931407942, Blast_Score=92, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560308, Length=579, Percent_Identity=22.7979274611399, Blast_Score=91, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17558820, Length=526, Percent_Identity=24.3346007604563, Blast_Score=89, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71985884, Length=404, Percent_Identity=23.019801980198, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17557194, Length=546, Percent_Identity=23.0769230769231, Blast_Score=85, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17531443, Length=545, Percent_Identity=21.8348623853211, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560140, Length=563, Percent_Identity=19.538188277087, Blast_Score=79, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534440, Length=502, Percent_Identity=22.9083665338645, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17559526, Length=388, Percent_Identity=25.2577319587629, Blast_Score=68, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=677, Percent_Identity=29.9852289512555, Blast_Score=275, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6319699, Length=195, Percent_Identity=28.7179487179487, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648676, Length=613, Percent_Identity=28.7112561174551, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24582852, Length=643, Percent_Identity=23.950233281493, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24581924, Length=554, Percent_Identity=22.3826714801444, Blast_Score=87, Evalue=7e-17,
Organism=Drosophila melanogaster, GI19922652, Length=531, Percent_Identity=22.0338983050847, Blast_Score=74, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24648260, Length=497, Percent_Identity=20.523138832998, Blast_Score=68, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 123041; Mature: 123041

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTLNQKMIEDIYPLSSLQQGMLFHSLYAPNSGAYVVQVSYELHGNLNIAAFEAAWQDL
CCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCEEEEEHHHHHHHH
INRHPVLRTAFVWDNLEKPLQVVGKQVKCQINHLDWSDVSVQQQQEALKVLLLQKQREQG
HCCCCCCEEHHHHHCCCHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
FNLSQAPLMQMTLIQLKSEVYQFVWSYHHLLLDGWSVQVLLKEFIVIYQAYIQQQTPVLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEE
NPRRYRDYIGWLQQQNLAEAETFWKQQLQGFVSPTQLNVGQNLDVRPDNLHSHYHEEKIQ
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHCCCCEE
LSVELTSKLQTLAKQQQLTINTFVQGAWALLLSRYSGEKNVLFATVSAGRPSALNGADAM
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHH
VGLFINTLPFRVLVSPEETLYQWLQKLQNQQVEIRQYEYSSLVDIHRWSQVSPSIPLFET
HHHHHHCCCEEEEECCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCCCCCHHHH
LVVFENYPIEPALKQSLASLEIRNIQATEQTNYPLTLYAVVDSQLALRILYDSDRFHHTT
HHHHCCCCCCHHHHHHHHHHEEECEECCCCCCCCEEEEEEECCCEEEEEEECCCCCCHHH
ITQILEQLETLLLGMTQGDCNLATLPFLSPTQQQQILIDWNATTQEIPQQCVHEIISQQA
HHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
QQTPDATAVVFADKTLTYAELNAKSNQIAHYLLQLGIKPEARIGVYLERSSPLLIIALLG
HCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHH
ILKAGAAYVPLDPTFPPERLRFMMADAELKLLLTQTSLTSVITDKIATINLDELEEDISQ
HHHCCCEEECCCCCCCHHHHHHHEECCEEEEEEEHHHHHHHHHHHHEECCHHHHHHHHHH
QPIFDPQIKVTPEQLTYLIYTSGSTGQPKGVMIEGRSLVNILTDLKQRLSITPNDKLLAV
CCCCCCCEEECHHHEEEEEEECCCCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCEEEE
TTIAFDIAALELFLPLIAGAQVVLPPQTALVDPRQLANCIEHHQITIMQATPATWRLLLA
HHHHHHHHHHHHHHHHHCCCEEEECCCHHCCCHHHHHHHHHHCEEEEEEECCHHEEEEEE
SGWEGKQDLKILCGGEALENTLAQQLLSCSQEVWNLYGPTETTIWSAAQKLSIDEPVTIG
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
HPIANTQFYILDEQLQPVPIGVPGELYIGGAGVARGYWKRPDLTAERFKGLGTGQRNYPT
CCCCCCEEEEEECCCCCCCCCCCCCEEECCCHHCCCCCCCCCCCHHHHCCCCCCCCCCCC
PYSLLPTPLYKTGDRVRYLRDGKLEYLGRLDYQIKIRGFRIELGEIEAVLAQHPAVEQAV
CCCCCCCCCCCCCCCEEEEECCCCHHHCCCCEEEEEEEEEEEHHHHHHHHHCCCCHHHHH
VTLREDEPGEQRLVAYIVSHPEIIPTELRTFLGEKLPIYMMPSAFILLEKFPLTPNGKID
HEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEECCCCEEEEEECCCCCCCCCC
RKALPKSNNLPLTTTNNFIPPQTQIEQTLSDIWQQLLGREKISIHDNFFDLGGHSLLIVR
CCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCCEEEEEE
MQGQLTLKLNQNIPLVDLFRYPTINSLAKYLTQNTPTSDKEIENRISQQQTGKQRLLQQR
ECCEEEEEECCCCCEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QTRLKT
HHHCCC
>Mature Secondary Structure
MNTTLNQKMIEDIYPLSSLQQGMLFHSLYAPNSGAYVVQVSYELHGNLNIAAFEAAWQDL
CCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCEEEEEHHHHHHHH
INRHPVLRTAFVWDNLEKPLQVVGKQVKCQINHLDWSDVSVQQQQEALKVLLLQKQREQG
HCCCCCCEEHHHHHCCCHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
FNLSQAPLMQMTLIQLKSEVYQFVWSYHHLLLDGWSVQVLLKEFIVIYQAYIQQQTPVLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEE
NPRRYRDYIGWLQQQNLAEAETFWKQQLQGFVSPTQLNVGQNLDVRPDNLHSHYHEEKIQ
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHCCCCEE
LSVELTSKLQTLAKQQQLTINTFVQGAWALLLSRYSGEKNVLFATVSAGRPSALNGADAM
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHH
VGLFINTLPFRVLVSPEETLYQWLQKLQNQQVEIRQYEYSSLVDIHRWSQVSPSIPLFET
HHHHHHCCCEEEEECCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCCCCCHHHH
LVVFENYPIEPALKQSLASLEIRNIQATEQTNYPLTLYAVVDSQLALRILYDSDRFHHTT
HHHHCCCCCCHHHHHHHHHHEEECEECCCCCCCCEEEEEEECCCEEEEEEECCCCCCHHH
ITQILEQLETLLLGMTQGDCNLATLPFLSPTQQQQILIDWNATTQEIPQQCVHEIISQQA
HHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
QQTPDATAVVFADKTLTYAELNAKSNQIAHYLLQLGIKPEARIGVYLERSSPLLIIALLG
HCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHH
ILKAGAAYVPLDPTFPPERLRFMMADAELKLLLTQTSLTSVITDKIATINLDELEEDISQ
HHHCCCEEECCCCCCCHHHHHHHEECCEEEEEEEHHHHHHHHHHHHEECCHHHHHHHHHH
QPIFDPQIKVTPEQLTYLIYTSGSTGQPKGVMIEGRSLVNILTDLKQRLSITPNDKLLAV
CCCCCCCEEECHHHEEEEEEECCCCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCEEEE
TTIAFDIAALELFLPLIAGAQVVLPPQTALVDPRQLANCIEHHQITIMQATPATWRLLLA
HHHHHHHHHHHHHHHHHCCCEEEECCCHHCCCHHHHHHHHHHCEEEEEEECCHHEEEEEE
SGWEGKQDLKILCGGEALENTLAQQLLSCSQEVWNLYGPTETTIWSAAQKLSIDEPVTIG
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
HPIANTQFYILDEQLQPVPIGVPGELYIGGAGVARGYWKRPDLTAERFKGLGTGQRNYPT
CCCCCCEEEEEECCCCCCCCCCCCCEEECCCHHCCCCCCCCCCCHHHHCCCCCCCCCCCC
PYSLLPTPLYKTGDRVRYLRDGKLEYLGRLDYQIKIRGFRIELGEIEAVLAQHPAVEQAV
CCCCCCCCCCCCCCCEEEEECCCCHHHCCCCEEEEEEEEEEEHHHHHHHHHCCCCHHHHH
VTLREDEPGEQRLVAYIVSHPEIIPTELRTFLGEKLPIYMMPSAFILLEKFPLTPNGKID
HEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEECCCCEEEEEECCCCCCCCCC
RKALPKSNNLPLTTTNNFIPPQTQIEQTLSDIWQQLLGREKISIHDNFFDLGGHSLLIVR
CCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCCEEEEEE
MQGQLTLKLNQNIPLVDLFRYPTINSLAKYLTQNTPTSDKEIENRISQQQTGKQRLLQQR
ECCEEEEEECCCCCEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QTRLKT
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA