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The map label for this gene is gap1 [H]

Identifier: 17230058

GI number: 17230058

Start: 3065473

End: 3066504

Strand: Reverse

Name: gap1 [H]

Synonym: all2566

Alternate gene names: 17230058

Gene position: 3066504-3065473 (Counterclockwise)

Preceding gene: 17230059

Following gene: 17230056

Centisome position: 47.81

GC content: 46.32

Gene sequence:

>1032_bases
TTGGCGAAATTAAAAGTTGGCATCAATGGATTCGGTCGTATCGGGCGACTTGTGCTTCGTGCTGGCATTAACAACCCCAA
CATTGAGTTTGTCGGGATTAACGACCTCGTACCACCCGATAACCTAGCTTACTTATTAAAGTACGACTCTACCCACGGTA
GGTTAAGAAGCCAGGTTGAAACCAAAGATGATGGTATTGTTATCGATGGACATTTTATTCCCTGTGTATCAGTCAGAAAC
CCAGCAGAATTACCTTGGGGAAAATTAGGTGCTGATTACGTCGTAGAATCGACTGGATTATTTACTGATTCTGAGGGCGC
ATCTAAGCATCTACAAGCAGGGGCGAGGCGCGTCATAATTTCCGCACCTACCAAAGACCCGGATAGAGTGCGGACGCTGT
TGGTTGGGGTGAACCATGATTTATTTGACCCCAGCAAAGATTTAATTGTCTCCAATGCTAGCTGTACCACTAACTGCCTA
GCACCCATTGCTAAGGTAATCAACGACAACTTTGGTTTAACCGAAGGGTTAATGACCACAGTTCATGCCATGACTGCTAC
CCAACCCACGGTAGACGGCCCCAGCAAAAAAGACTGGCGCGGTGGTAGAGGTGCAGCCCAAAATATTATTCCCTCTTCCA
CAGGTGCAGCCAAAGCAGTGGCGTTGGTTTTACCAGAGTTGAAAGGTAAGTTAACTGGTATGGCTTTCCGCGTTCCTACC
CCAGATGTTTCCGTTGTAGATTTAACATTCAAAACTGCCAAAGCCACCAGCTACAAAGAAATTTGTGCAGCGATGAAGCA
AGCATCTGAAGGTTCACTAGCTGGTATTCTTGGTTACACCGACGAAGAAGTAGTTTCCACAGATTTTCAGGGTGATACTC
ATTCCAGCATCTTCGACGCAGGCGCGGGGATCGAGCTAAACTCCAACTTCTTCAAGGTAGTAGCTTGGTATGACAACGAG
TGGGGCTACTCTAATCGTGTAGTTGACCTGATGTTGTCAATGGTACAAAAAGAACAACTGGCTGCTGTTTAA

Upstream 100 bases:

>100_bases
CACGATCAGCTCAGTCAGACTAAAATTCACCTGGCTATTTGCAGTGTTGAAGCTAGGGTAAACGCCCAGATTAATTTGAC
AAAAATGTAGGAGGTTAGTT

Downstream 100 bases:

>100_bases
CAGTTATCAGTTATTCGGTGAGCAGTTAGTCTGACTTTTCACTGTATCTGGAAAACCCCTCTCCAAACCTCTCCCCTGCA
AGGAGAGAGGCTTTGATTGC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MAKLKVGINGFGRIGRLVLRAGINNPNIEFVGINDLVPPDNLAYLLKYDSTHGRLRSQVETKDDGIVIDGHFIPCVSVRN
PAELPWGKLGADYVVESTGLFTDSEGASKHLQAGARRVIISAPTKDPDRVRTLLVGVNHDLFDPSKDLIVSNASCTTNCL
APIAKVINDNFGLTEGLMTTVHAMTATQPTVDGPSKKDWRGGRGAAQNIIPSSTGAAKAVALVLPELKGKLTGMAFRVPT
PDVSVVDLTFKTAKATSYKEICAAMKQASEGSLAGILGYTDEEVVSTDFQGDTHSSIFDAGAGIELNSNFFKVVAWYDNE
WGYSNRVVDLMLSMVQKEQLAAV

Sequences:

>Translated_343_residues
MAKLKVGINGFGRIGRLVLRAGINNPNIEFVGINDLVPPDNLAYLLKYDSTHGRLRSQVETKDDGIVIDGHFIPCVSVRN
PAELPWGKLGADYVVESTGLFTDSEGASKHLQAGARRVIISAPTKDPDRVRTLLVGVNHDLFDPSKDLIVSNASCTTNCL
APIAKVINDNFGLTEGLMTTVHAMTATQPTVDGPSKKDWRGGRGAAQNIIPSSTGAAKAVALVLPELKGKLTGMAFRVPT
PDVSVVDLTFKTAKATSYKEICAAMKQASEGSLAGILGYTDEEVVSTDFQGDTHSSIFDAGAGIELNSNFFKVVAWYDNE
WGYSNRVVDLMLSMVQKEQLAAV
>Mature_342_residues
AKLKVGINGFGRIGRLVLRAGINNPNIEFVGINDLVPPDNLAYLLKYDSTHGRLRSQVETKDDGIVIDGHFIPCVSVRNP
AELPWGKLGADYVVESTGLFTDSEGASKHLQAGARRVIISAPTKDPDRVRTLLVGVNHDLFDPSKDLIVSNASCTTNCLA
PIAKVINDNFGLTEGLMTTVHAMTATQPTVDGPSKKDWRGGRGAAQNIIPSSTGAAKAVALVLPELKGKLTGMAFRVPTP
DVSVVDLTFKTAKATSYKEICAAMKQASEGSLAGILGYTDEEVVSTDFQGDTHSSIFDAGAGIELNSNFFKVVAWYDNEW
GYSNRVVDLMLSMVQKEQLAAV

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=339, Percent_Identity=61.3569321533923, Blast_Score=421, Evalue=1e-118,
Organism=Homo sapiens, GI7657116, Length=338, Percent_Identity=59.1715976331361, Blast_Score=414, Evalue=1e-116,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=62.5, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=36.8263473053892, Blast_Score=235, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI17534677, Length=337, Percent_Identity=61.7210682492582, Blast_Score=414, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI32566163, Length=343, Percent_Identity=60.3498542274053, Blast_Score=412, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17568413, Length=343, Percent_Identity=60.3498542274053, Blast_Score=412, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17534679, Length=337, Percent_Identity=61.1275964391691, Blast_Score=412, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6322409, Length=329, Percent_Identity=61.0942249240122, Blast_Score=409, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6321631, Length=330, Percent_Identity=60.3030303030303, Blast_Score=404, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6322468, Length=330, Percent_Identity=60.3030303030303, Blast_Score=403, Evalue=1e-113,
Organism=Drosophila melanogaster, GI17933600, Length=335, Percent_Identity=60.8955223880597, Blast_Score=404, Evalue=1e-113,
Organism=Drosophila melanogaster, GI18110149, Length=335, Percent_Identity=60.8955223880597, Blast_Score=404, Evalue=1e-113,
Organism=Drosophila melanogaster, GI85725000, Length=335, Percent_Identity=60.8955223880597, Blast_Score=403, Evalue=1e-113,
Organism=Drosophila melanogaster, GI22023983, Length=335, Percent_Identity=60.8955223880597, Blast_Score=403, Evalue=1e-113,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=51.5243902439024, Blast_Score=341, Evalue=4e-94,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36752; Mature: 36621

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLKVGINGFGRIGRLVLRAGINNPNIEFVGINDLVPPDNLAYLLKYDSTHGRLRSQVE
CCEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHCC
TKDDGIVIDGHFIPCVSVRNPAELPWGKLGADYVVESTGLFTDSEGASKHLQAGARRVII
CCCCCEEECCCEEEEEECCCCCCCCCCCCCCCEEEECCCCEECCCCCHHHHHCCCEEEEE
SAPTKDPDRVRTLLVGVNHDLFDPSKDLIVSNASCTTNCLAPIAKVINDNFGLTEGLMTT
ECCCCCHHHHEEEEEECCCCCCCCCHHEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHH
VHAMTATQPTVDGPSKKDWRGGRGAAQNIIPSSTGAAKAVALVLPELKGKLTGMAFRVPT
HHHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCC
PDVSVVDLTFKTAKATSYKEICAAMKQASEGSLAGILGYTDEEVVSTDFQGDTHSSIFDA
CCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHCCCCCCCCCCHHHHC
GAGIELNSNFFKVVAWYDNEWGYSNRVVDLMLSMVQKEQLAAV
CCCEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKLKVGINGFGRIGRLVLRAGINNPNIEFVGINDLVPPDNLAYLLKYDSTHGRLRSQVE
CEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHCC
TKDDGIVIDGHFIPCVSVRNPAELPWGKLGADYVVESTGLFTDSEGASKHLQAGARRVII
CCCCCEEECCCEEEEEECCCCCCCCCCCCCCCEEEECCCCEECCCCCHHHHHCCCEEEEE
SAPTKDPDRVRTLLVGVNHDLFDPSKDLIVSNASCTTNCLAPIAKVINDNFGLTEGLMTT
ECCCCCHHHHEEEEEECCCCCCCCCHHEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHH
VHAMTATQPTVDGPSKKDWRGGRGAAQNIIPSSTGAAKAVALVLPELKGKLTGMAFRVPT
HHHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCC
PDVSVVDLTFKTAKATSYKEICAAMKQASEGSLAGILGYTDEEVVSTDFQGDTHSSIFDA
CCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHCCCCCCCCCCHHHHC
GAGIELNSNFFKVVAWYDNEWGYSNRVVDLMLSMVQKEQLAAV
CCCEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]